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PGM5 Gene

protein-coding   GIFtS: 58
GCID: GC09P070971

Phosphoglucomutase 5

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Phosphoglucomutase 51 2     aciculin2
Phosphoglucomutase-Related Protein1 2 3     Phosphoglucomutase-Like Protein 52
PGM-RP2 3     Aciculin3
PGMRP2 3     EC 5.4.2.28

External Ids:    HGNC: 89081   Entrez Gene: 52392   Ensembl: ENSG000001543307   OMIM: 6009815   UniProtKB: Q151243   

Export aliases for PGM5 gene to outside databases

Previous GC identifers: GC09P062016 GC09P062828 GC09P064541 GC09P066429 GC09P066428 GC09P068201 GC09P070161 GC09P040808


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for PGM5 Gene:
Phosphoglucomutases (EC 5.2.2.2.), such as PGM5, are phosphotransferases involved in interconversion of
glucose-1-phosphate and glucose-6-phosphate. PGM activity is essential in formation of carbohydrates from
glucose-6-phosphate and in formation of glucose-6-phosphate from galactose and glycogen (Edwards et al., 1995
(PubMed 8586438)).(supplied by OMIM, Mar 2008)

GeneCards Summary for PGM5 Gene:
PGM5 (phosphoglucomutase 5) is a protein-coding gene. GO annotations related to this gene include structural molecule activity and phosphoglucomutase activity. An important paralog of this gene is PGM1.

UniProtKB/Swiss-Prot: PGM5_HUMAN, Q15124
Function: Component of adherens-type cell-cell and cell-matrix junctions. Lacks phosphoglucomutase activity

Gene Wiki entry for PGM5 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000009.11  NC_018920.2  NT_008470.20  
Regulatory elements:
   Regulatory transcription factor binding sites in the PGM5 gene promoter:
         RP58   AML1a   GATA-3   NF-kappaB   CREB   HFH-1   deltaCREB   FOXJ2 (long isoform)   FOXJ2   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidPGM5 promoter sequence
   Search Chromatin IP Primers for PGM5

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat PGM5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q13   Ensembl cytogenetic band:  9q21.11   HGNC cytogenetic band: 9q13

PGM5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PGM5 gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09P070971:  view genomic region     (about GC identifiers)

Start:
70,943,224 bp from pter      End:
71,145,977 bp from pter
Size:
202,754 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: PGM5_HUMAN, Q15124 (See protein sequence)
Recommended Name: Phosphoglucomutase-like protein 5  
Size: 567 amino acids; 62225 Da
Cofactor: Binds 1 magnesium ion per subunit (Potential)
Subunit: Interacts with cytoskeletal proteins dystrophin and utrophin
Developmental stage: In the developing aorta, expressed at low levels in 10-12 week old fetuses. Levels increase
progressively in 24 week fetus, 6 month old child and 1.5 year old child aortic smooth muscle, reaching a maximum
at maturity
Sequence caution: Sequence=AAC41948.1; Type=Erroneous initiation; Sequence=AAH33073.1; Type=Erroneous initiation;
Sequence=CAA73882.1; Type=Erroneous initiation;
Secondary accessions: B1AM46 B4DLQ6 Q5VYV3 Q8N527 Q9UDH4
Alternative splicing: 2 isoforms:  Q15124-1   Q15124-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for PGM5: NX_Q15124

Explore proteomics data for PGM5 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus
  • 4 DME Specific Peptides for PGM5 (Q15124)
     LSTPAVS  GILSTPA  HPDPNLTYA  CGEESFGTG 


    See PGM5 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_068800.2  
    ENSEMBL proteins: 
     ENSP00000379674   ENSP00000379678   ENSP00000394864  

    PGM5 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for PGM5

     
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    antibodies-online proteins for PGM5 (5 products) 

     
    antibodies-online peptides for PGM5

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    antibodies-online antibodies for PGM5 (16 products) 

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    Selected InterPro protein domains (see all 6):
     IPR016066 A-D-PHexomutase_CS
     IPR016055 A-D-PHexomutase_a/b/a-I/II/III
     IPR005841 Alpha-D-phosphohexomutase_SF
     IPR005844 A-D-PHexomutase_a/b/a-I
     IPR005846 A-D-PHexomutase_a/b/a-III

    Graphical View of Domain Structure for InterPro Entry Q15124

    ProtoNet protein and cluster: Q15124

    1 Blocks protein domain: IPB001254 Serine protease

    UniProtKB/Swiss-Prot: PGM5_HUMAN, Q15124
    Similarity: Belongs to the phosphohexose mutase family


    Find genes that share domains with PGM5           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: PGM5_HUMAN, Q15124
    Function: Component of adherens-type cell-cell and cell-matrix junctions. Lacks phosphoglucomutase activity

         Genatlas biochemistry entry for PGM5:
    phosphoglucomutase 5,with homology to PGM1 but unknown function,widely expressed in fetal and adult tissues

         Enzyme Number (IUBMB): EC 5.4.2.22

         Gene Ontology (GO): 5 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000287magnesium ion binding IEA--
    GO:0004614NOT phosphoglucomutase activity IDA8175905
    GO:0005198structural molecule activity NAS8631316
    GO:0005515protein binding ----
    GO:0016868intramolecular transferase activity, phosphotransferases ----
         
    Find genes that share ontologies with PGM5           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for PGM5:
     Increased gamma-H2AX phosphory 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for PGM5

    miRNA
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    miRTarBase miRNAs that target PGM5:
    hsa-mir-335-5p (MIRT017304), hsa-mir-124-3p (MIRT022385)

    Block miRNA regulation of human, mouse, rat PGM5 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate PGM5 (see all 11):
    hsa-miR-3910 hsa-miR-548p hsa-miR-328 hsa-miR-3660 hsa-miR-1224-3p hsa-miR-1260b hsa-miR-1260 hsa-miR-1291
    SwitchGear 3'UTR luciferase reporter plasmidPGM5 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat PGM5

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    PGM5_HUMAN, Q15124: Cell junction, adherens junction. Cytoplasm, cytoskeleton. Note=Adherens-type cellular
    junctions. Concentrated in focal contacts at the ends of actin bundles, and associated with actin filaments
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton5
    plasma membrane5
    cytosol3

    Gene Ontology (GO): Selected cellular component terms (see all 12):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001725stress fiber IDA8175905
    GO:0005829NOT cytosol IBA--
    GO:0005913cell-cell adherens junction IDA8175905
    GO:0005914spot adherens junction IDA8175905
    GO:0005925focal adhesion IDA8175905

    Find genes that share ontologies with PGM5           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for PGM5 About    
    See pathways by source

    SuperPathContained pathways About
    1Glucuronidation
    Glucuronidation0.61


    1 BioSystems Pathway for PGM5
        Glucuronidation


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for PGM5
    Interactions:

        Search GeneGlobe Interaction Network for PGM5

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for PGM5 (Q151243 ENSP000003796784) via UniProtKB, MINT, STRING, and/or I2D (see all 33)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UTRNP469393, ENSP000003565154I2D: score=2 STRING: ENSP00000356515
    DMDP115323, ENSP000003549234I2D: score=3 STRING: ENSP00000354923
    CAV3ENSP000003419404STRING: ENSP00000341940
    DAG1ENSP000003124354STRING: ENSP00000312435
    SGCAENSP000002620184STRING: ENSP00000262018
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005975carbohydrate metabolic process ----
    GO:0005978NOT glycogen biosynthetic process IBA--
    GO:0005992NOT trehalose biosynthetic process IBA--
    GO:0006006glucose metabolic process IEA--
    GO:0007155cell adhesion IEA--

    Find genes that share ontologies with PGM5           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for PGM5

    1 HMDB Compound for PGM5    About this table
    CompoundSynonyms CAS #PubMed Ids
    MagnesiumMagnesium (see all 2)7439-95-4--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for PGM5 gene: 
    NM_021965.3  

    Unigene Cluster for PGM5:

    Phosphoglucomutase 5
    Hs.307835  [show with all ESTs]
    Unigene Representative Sequence: AL137698
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000604870 ENST00000396392 ENST00000396396(uc004agr.3) ENST00000431583
    ENST00000587852 ENST00000472639 ENST00000496758
    miRNA
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    Block miRNA regulation of human, mouse, rat PGM5 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate PGM5 (see all 11):
    hsa-miR-3910 hsa-miR-548p hsa-miR-328 hsa-miR-3660 hsa-miR-1224-3p hsa-miR-1260b hsa-miR-1260 hsa-miR-1291
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    Inhib. RNA
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      QuantiTect SYBR Green Assays in human, mouse, rat PGM5
      QuantiFast Probe-based Assays in human, mouse, rat PGM5

    Additional mRNA sequence: 

    AK297108.1 AL137698.1 BC033073.1 

    6 DOTS entries:

    DT.414970  DT.95311414  DT.100025722  DT.121153071  DT.75127860  DT.97817207 

    Selected AceView cDNA sequences (see all 94):

    BF793292 NM_021965 AA709405 AA688336 BQ890368 BM699018 CB269083 BQ001679 
    CA437740 BX094630 AI095018 AA070085 AI078570 AL046941 AA715132 BP379938 
    AL710966 AI361547 AL137698 N48799 CA444223 AA706810 CA431930 AA151401 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for PGM5    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11
    SP1:                                                                              
    SP2:                                            -     -                           
    SP3:                                                                              
    SP4:                                                                              


    ECgene alternative splicing isoforms for PGM5

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    PGM5 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGTGAGAGCT
    PGM5 Expression
    About this image


    PGM5 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 6) fully expand
     
     Heart (Cardiovascular System)
             Cardiomyocyte-like progenitor cells
     
     Kidney (Urinary System)
             Metanephric Mesenchyme Cells Metanephric Mesenchyme
     
     Esophagus (Gastrointestinal Tract)
     
     Adrenal Gland (Endocrine System)
     
     Uterus (Reproductive System)
    PGM5 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    PGM5 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.307835

    UniProtKB/Swiss-Prot: PGM5_HUMAN, Q15124
    Tissue specificity: Detected in smooth and cardiac muscle at high levels and in skeletal muscle at low level.
    Present in other tissues due to vascular or other smooth muscle component. Low levels are present in liver,
    kidney, skin and brain (at protein level)

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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for PGM5 gene from Selected species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Pgm51 , 5 phosphoglucomutase 51, 5 90.83(n)1
    97.53(a)1
      19 (19.78 cM)5
    2260411  NM_175013.21  NP_778178.31 
     246830165 
    chicken
    (Gallus gallus)
    Aves PGM51 phosphoglucomutase 5 80.6(n)
    88.54(a)
      427215  XM_424802.4  XP_424802.3 
    lizard
    (Anolis carolinensis)
    Reptilia PGM56
    phosphoglucomutase 5
    87(a)
    1 ↔ 1
    2(49911652-49971753)
    zebrafish
    (Danio rerio)
    Actinopterygii pgm51 phosphoglucomutase 5 72.73(n)
    77.21(a)
      560297  NM_001126396.1  NP_001119868.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Pgm6
    Phosphogluconate mutase
    49(a)
    1 → many
    3L(16119118-16121631)
    worm
    (Caenorhabditis elegans)
    Secernentea R05F9.63 phosphoglucomutase 53(a)   II(4889433-4891290)   --
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes PGM26
    PGM16
    Phosphoglucomutase, catalyzes the conversion from ...
    Phosphoglucomutase, minor isoform; catalyzes the c...
    43(a)
    41(a)
    many ↔ many
    many ↔ many
    XIII(475897-477606) YMR105C
    XI(203541-205253) YKL127W
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT1G707301 AT1G70730 54.91(n)
    54.07(a)
      843410  NM_001160993.1  NP_001154465.1 
    rice
    (Oryza sativa)
    Liliopsida Os03g07127001 Os03g0712700 56.02(n)
    52.37(a)
      4333895  NM_001057601.1  NP_001051066.1 


    ENSEMBL Gene Tree for PGM5 (if available)
    TreeFam Gene Tree for PGM5 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for PGM5 gene
    PGM12  
    1 SIMAP similar gene for PGM5 using alignment to 2 protein entries:     PGM5_HUMAN (see all proteins):
    PGM1

    Find genes that share paralogs with PGM5           About GenesLikeMe


    4 Pseudogenes.org Pseudogenes for PGM5
    PGOHUM00000240872 PGOHUM00000235941 PGOHUM00000263221 PGOHUM00000263222


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for PGM5 (see all 3233)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 9 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs3725811,2
    F,H--70975096(-) GCAATT/CACATA 1 -- int18Minor allele frequency- C:0.02NS EA NA 1224
    rs1923612701,2
    --70975282(+) AAACAC/TTATAA 1 -- int10--------
    rs1828899461,2
    --70975628(+) TTCCTA/GTATTT 1 -- int10--------
    rs1875285451,2
    --70975747(+) AGTTAC/TGAAAT 1 -- int10--------
    rs1479525611,2
    C--70975751(+) ACGAA-/ATCATCTT 1 -- int10--------
    rs31196521,2
    C,F--70975778(-) AAAACC/TATTTT 1 -- int11Minor allele frequency- T:0.12NA 120
    rs1923115071,2
    --70975869(+) TTGCTC/TTTTCA 1 -- int10--------
    rs27771611,2
    --70975923(-) caggaA/Gtttga 1 -- int10--------
    rs74705981,2
    C,F--70976000(+) cagctA/Cattta 1 -- int11Minor allele frequency- C:0.00NA 2
    rs1383481831,2
    C--70976020(+) TAGAGA/GTGGAG 1 -- int10--------

    HapMap Linkage Disequilibrium report for PGM5 (70943224 - 71145977 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for PGM5 (see all 14):    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv8521CNV Loss18304495
    nsv428218CNV Loss18775914
    dgv8241n71CNV Gain21882294
    nsv8520CNV Gain18304495
    nsv831609CNV Gain17160897
    dgv8238n71CNV Gain21882294
    nsv8519CNV Gain18304495
    dgv8240n71CNV Gain21882294
    nsv893414CNV Gain21882294
    dgv8242n71CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 600981    OMIM disorders: --


    Find genes that share disorders with PGM5           About GenesLikeMe


    Export disorders for PGM5 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for PGM5 gene, integrated from 10 sources (see all 14):
    (articles sorted by number of sources associating them with PGM5)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A novel dystrophin/utrophin-associated protein is an enzymatically inactive member of the phosphoglucomutase superfamily. (PubMed id 8631316)1, 2, 3, 9 Moiseeva E.P....Critchley D.R. (Eur. J. Biochem. 1996)
    2. Characterisation of the promoter which regulates expression of a phosphoglucomutase-related protein, a component of the dystrophin/utrophin cytoskeleton predominantly expressed in smooth muscle. (PubMed id 9342213)1, 2, 9 Moiseeva E.P. and Critchley D.R. (Eur. J. Biochem. 1997)
    3. A novel human phosphoglucomutase (PGM5) maps to the centromeric region of chromosome 9. (PubMed id 8586438)1, 3, 9 Edwards Y.H....Ives J.H. (Genomics 1995)
    4. A novel phosphoglucomutase-related protein is concentrated in adherens junctions of muscle and nonmuscle cells. (PubMed id 8175905)1, 2 Belkin A.M.... Koteliansky V.E. (J. Cell Sci. 1994)
    5. Association of aciculin with dystrophin and utrophin. (PubMed id 7890770)1, 9 Belkin A.M. and Burridge K. (J. Biol. Chem. 1995)
    6. Localization of utrophin and aciculin at sites of cell-matrix and cell-cell adhesion in cultured cells. (PubMed id 7589238)1, 9 Belkin A.M. and Burridge K. (Exp. Cell Res. 1995)
    7. Aciculin and its relation to dystrophin: immunocytochemical studies in human normal and Duchenne dystrophy quadriceps muscles. (PubMed id 10867799)1, 9 Wakayama Y....Oniki H. (Acta Neuropathol. 2000)
    8. A genome-wide association study of seasonal pattern mania identifies NF1A as a possible susceptibility gene for bipolar disorder. (PubMed id 22925353)1 Lee H.J....Kelsoe J.R. (J Affect Disord 2013)
    9. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 5239 HGNC: 8908 AceView: PGM5 Ensembl:ENSG00000154330 euGenes: HUgn5239
    ECgene: PGM5 H-InvDB: PGM5

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for PGM5 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for PGM5 gene:
    Search GeneIP for patents involving PGM5

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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