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PGK2 Gene

protein-coding   GIFtS: 61
GCID: GC06M049753

Phosphoglycerate Kinase 2

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Phosphoglycerate Kinase 21 2     PGKPS2
Phosphoglycerate Kinase, Testis Specific2 3     dJ417L20.22
PGKB2 3     Epididymis Secretory Protein Li 2722
EC 2.7.2.33 8     Phosphoglycerate Kinase Autosomal Pseudogene2
HEL-S-2722     

External Ids:    HGNC: 88981   Entrez Gene: 52322   Ensembl: ENSG000001709507   OMIM: 1722705   UniProtKB: P072053   

Export aliases for PGK2 gene to outside databases

Previous GC identifers: GC06M049755 GC06M049800 GC06M049861 GC06M049483


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for PGK2 Gene:
This gene is intronless, arose via retrotransposition of the phosphoglycerate kinase 1 gene, and is expressed
specifically in the testis. Initially assumed to be a pseudogene, the encoded protein is actually a functional
phosphoglycerate kinase that catalyzes the reversible conversion of 1,3-bisphosphoglycerate to
3-phosphoglycerate, during the Embden-Meyerhof-Parnas pathway of glycolysis, in the later stages of
spermatogenesis.(provided by RefSeq, May 2010)

GeneCards Summary for PGK2 Gene:
PGK2 (phosphoglycerate kinase 2) is a protein-coding gene. GO annotations related to this gene include phosphoglycerate kinase activity. An important paralog of this gene is PGK1.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000006.11  NC_018917.2  NT_007592.16  
Regulatory elements:
   Regulatory transcription factor binding sites in the PGK2 gene promoter:
         c-Fos   AP-1   JunB   Fra-1   FosB   CUTL1   Roaz   PPAR-alpha   Nkx6-1   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidPGK2 promoter sequence
   Search Chromatin IP Primers for PGK2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat PGK2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p12.3   Ensembl cytogenetic band:  6p12.3   HGNC cytogenetic band: 6p12.3

PGK2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PGK2 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M049753:  view genomic region     (about GC identifiers)

Start:
49,753,364 bp from pter      End:
49,755,053 bp from pter
Size:
1,690 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: PGK2_HUMAN, P07205 (See protein sequence)
Recommended Name: Phosphoglycerate kinase 2  
Size: 417 amino acids; 44796 Da
Subunit: Monomer (By similarity)
Secondary accessions: B2R6Y8 Q9H107

Explore the universe of human proteins at neXtProt for PGK2: NX_P07205

Explore proteomics data for PGK2 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys91, Lys156
  • Modification sites at PhosphoSitePlus
  • Selected DME Specific Peptides for PGK2 (P07205) (see all 26)
     ITNNQRI  PSIKYCL  SLFDEEG  LLENLRF 


    See PGK2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_620061.2  
    ENSEMBL proteins: 
     ENSP00000305995  

    PGK2 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    4 InterPro protein domains:
     IPR001576 Phosphoglycerate_kinase
     IPR015824 Phosphoglycerate_kinase_N
     IPR015901 Phosphoglycerate_kinase_C
     IPR015911 Phosphoglycerate_kinase_CS

    Graphical View of Domain Structure for InterPro Entry P07205

    ProtoNet protein and cluster: P07205

    1 Blocks protein domain: IPB001576 Phosphoglycerate kinase

    UniProtKB/Swiss-Prot: PGK2_HUMAN, P07205
    Similarity: Belongs to the phosphoglycerate kinase family


    Find genes that share domains with PGK2           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: PGK2_HUMAN, P07205
    Catalytic activity: ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate

         Genatlas biochemistry entry for PGK2:
    phosphoglycerate kinase 2,specifically expressed in spermatogenic cell,highly homologous to PGK1,glycolysis,energy
    pathway,key enzyme for ATP generation

         Enzyme Number (IUBMB): EC 2.7.2.31 2

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004618phosphoglycerate kinase activity NAS3453121
    GO:0005524ATP binding ISS--
         
    Find genes that share ontologies with PGK2           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for PGK2:
     Increased cell death HMECs cel 

         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Pgk2):
     reproductive system 

    Find genes that share phenotypes with PGK2           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Pgk2tm1Dao for PGK2

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for PGK2
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for PGK2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for PGK2
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for PGK2

    miRNA
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    Block miRNA regulation of human, mouse, rat PGK2 using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate PGK2:
    hsa-miR-633
    SwitchGear 3'UTR luciferase reporter plasmidPGK2 3' UTR sequence
    Inhib. RNA
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    Sino Biological Human cDNA Clone for PGK2
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    Addgene plasmids for PGK2 

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PGK2


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    PGK2_HUMAN, P07205: Cytoplasm (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol5
    nucleus2
    chloroplast1
    lysosome1
    mitochondrion1
    peroxisome1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--
    GO:0005829cytosol ----

    Find genes that share ontologies with PGK2           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for PGK2 About    
    See pathways by source

    SuperPathContained pathways About
    1Glycolysis and gluconeogenesis short map
    Glycolysis and gluconeogenesis short map 0.60
    Glycolysis / Gluconeogenesis0.46
    Glycolysis and Gluconeogenesis0.60
    2Carbon metabolism
    Carbon metabolism0.38
    Biosynthesis of amino acids0.38
    3Metabolism
    Metabolic pathways0.38


    Find genes that share SuperPaths with PGK2           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 GeneGo (Thomson Reuters) Pathway for PGK2
        Glycolysis and gluconeogenesis (short map)

    1 BioSystems Pathway for PGK2
        Glycolysis and Gluconeogenesis



    4 Kegg Pathways  (Kegg details for PGK2):
        Glycolysis / Gluconeogenesis
    Metabolic pathways
    Carbon metabolism
    Biosynthesis of amino acids

    UniProtKB/Swiss-Prot: PGK2_HUMAN, P07205
    Pathway: Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5

        Pathway & Disease-focused RT2 Profiler PCR Array including PGK2: 

              Glucose Metabolism in human mouse rat

    Interactions:

        GeneGlobe Interaction Network for PGK2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for PGK2 (P072053 ENSP000003059954) via UniProtKB, MINT, STRING, and/or I2D (see all 86)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UBCP0CG483, ENSP000003448184I2D: score=1 STRING: ENSP00000344818
    GAPDHENSP000002292394STRING: ENSP00000229239
    GAPDHSENSP000002222864STRING: ENSP00000222286
    MMS19ENSP000003598184STRING: ENSP00000359818
    ENSG00000228532ENSP000003912664STRING: ENSP00000391266
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006096glycolytic process NAS3453121
    GO:0016310phosphorylation NAS3453121

    Find genes that share ontologies with PGK2           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for PGK2

    3 HMDB Compounds for PGK2    About this table
    CompoundSynonyms CAS #PubMed Ids
    2-Phosphoglyceric acid2-(dihydrogen phosphate)Glycerate (see all 16)2553-59-5--
    ADPadenosindiphosphorsaeure (see all 8)58-64-0--
    Adenosine triphosphate5'-(tetrahydrogen triphosphate) Adenosine (see all 24)56-65-5--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for PGK2 gene: 
    NM_138733.4  

    Unigene Cluster for PGK2:

    Phosphoglycerate kinase 2
    Hs.367727  [show with all ESTs]
    Unigene Representative Sequence: NM_138733
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000304801(uc003ozu.3)
    miRNA
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    1 qRT-PCR Assays for microRNA that regulate PGK2:
    hsa-miR-633
    SwitchGear 3'UTR luciferase reporter plasmidPGK2 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat PGK2
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      QuantiTect SYBR Green Assays in human, mouse, rat PGK2
      QuantiFast Probe-based Assays in human, mouse, rat PGK2

    Additional mRNA sequence: 

    AK312770.1 BC038843.1 

    2 DOTS entries:

    DT.91651170  DT.121343673 

    Selected AceView cDNA sequences (see all 31):

    BI825781 BP369517 CD171670 CD358467 BP371280 BI831468 BI831364 BU568460 
    BP370274 BP369546 BI831239 BM563802 BP369008 BI464092 BC038843 BG717359 
    BI827588 BG718080 BI827535 NM_138733 CD300101 BP368944 BP369088 BI832204 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    PGK2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCCCTTAAGT
    PGK2 Expression
    About this image


    PGK2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Testis (Reproductive System)    fully expand to see all 4 entries
             Mature Sertoli Cells Seminiferous Tubules
             Testis Interstitium
     
     Liver (Hepatobiliary System)
             Hepatocytes Liver Lobule
    PGK2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    PGK2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.367727

    UniProtKB/Swiss-Prot: PGK2_HUMAN, P07205
    Tissue specificity: Testis specific

        Pathway & Disease-focused RT2 Profiler PCR Array including PGK2: 
              Glucose Metabolism in human mouse rat

    Primer
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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for PGK2 gene from Selected species (see all 20)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Pgk21 , 5 phosphoglycerate kinase 21, 5 84.89(n)1
    85.85(a)1
      17 (19.44 cM)5
    186631  NM_031190.21  NP_112467.21 
     402070185 
    chicken
    (Gallus gallus)
    Aves PGK16
    Gallus gallus phosphoglycerate kinase 1 (PGK1), mR...
    82(a)
    1 → many
    4(12898194-12909392)
    lizard
    (Anolis carolinensis)
    Reptilia --
    Phosphoglycerate kinase
    83(a)
    1 → many
    GL343465.1(735609-750645)
    zebrafish
    (Danio rerio)
    Actinopterygii pgk16
    phosphoglycerate kinase 1
    81(a)
    1 → many
    21(36771669-36787616) ENSDARG00000054191
    fruit fly
    (Drosophila melanogaster)
    Insecta Pgk3 glycolysis phosphoglycerate kinase 68(a)
    (best of 2)
      23A3   --
    worm
    (Caenorhabditis elegans)
    Secernentea T03F1.33 phosphoglycerate kinase 69(a)   I(3867554-3868959)   --
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes PGK16
    3-phosphoglycerate kinase, catalyzes transfer of h...
    63(a)
    1 → many
    III(137746-138996) YCR012W
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons PGK1 PGK 56.5(n)
    50.65(a)
      844293  NM_106603.2  NP_178073.1 
    rice
    (Oryza sativa)
    Liliopsida AK070041.12   -- 75.66(n)    AK070041.1 


    ENSEMBL Gene Tree for PGK2 (if available)
    TreeFam Gene Tree for PGK2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for PGK2 gene
    PGK12  
    1 SIMAP similar gene for PGK2 using alignment to 1 protein entry:     PGK2_HUMAN:
    PGK1

    Find genes that share paralogs with PGK2           About GenesLikeMe


    2 Pseudogenes.org Pseudogenes for PGK2
    PGOHUM00000234519 PGOHUM00000241367


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for PGK2 (see all 117)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1853816641,2
    --49752879(+) TTCCCA/TTTATT 1 -- ds50010--------
    rs1440980951,2
    --49752884(+) ATTATG/TAAACC 1 -- ds50010--------
    rs1459910131,2
    --49752978(+) GCCTTA/CAAAAT 1 -- ds50010--------
    rs1909742031,2
    --49752987(+) ATAAAA/GCAATT 1 -- ds50010--------
    rs1486942071,2
    --49753010(+) CTTGGG/TTTTAA 1 -- ds50010--------
    rs1161472501,2
    C,F--49753029(+) TCTTTT/CTCTAG 1 -- ds50011Minor allele frequency- C:0.01NA 120
    rs6866121,2
    C,H--49753039(-) CAAATG/ACCAGC 1 -- ds50015Minor allele frequency- A:0.00NS EA NA 422
    rs1835048161,2
    --49753170(+) TATTTA/GGTATA 1 -- ds50010--------
    rs794246091,2
    C,F--49753259(+) ATTTAT/CTGTTT 1 -- ds50011Minor allele frequency- C:0.07WA 118
    rs1860925191,2
    --49753333(+) ATGAAA/GCAATA 1 -- ds50010--------

    HapMap Linkage Disequilibrium report for PGK2 (49753364 - 49755053 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for PGK2: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing PGK2
    DNA2.0 Custom Variant and Variant Library Synthesis for PGK2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 172270    OMIM disorders: --


    Find genes that share disorders with PGK2           About GenesLikeMe

    Genetic Association Database (GAD): PGK2

    Export disorders for PGK2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for PGK2 gene, integrated from 10 sources (see all 34):
    (articles sorted by number of sources associating them with PGK2)
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    1. Human testis-specific PGK gene lacks introns and possesses characteristics of a processed gene. (PubMed id 3453121)1, 2, 3 McCarrey J.R. and Thomas K. (Nature 1987)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (Nature 2003)
    4. Molecular cloning and structure of an autosomal processed gene for human phosphoglycerate kinase. (PubMed id 3839763)1, 3 Tani K....Yoshida A. (Gene 1985)
    5. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (amp 2012)
    6. Shotgun proteomics and network analysis of ubiquitin-related proteins from human breast carcinoma epithelial cells. (PubMed id 21853274)1 Zhou J....Liang S. (Mol. Cell. Biochem. 2012)
    7. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    8. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    9. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    10. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 5232 HGNC: 8898 AceView: PGK2 Ensembl:ENSG00000170950 euGenes: HUgn5232
    ECgene: PGK2 Kegg: 5232 H-InvDB: PGK2

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for PGK2 Pharmacogenomics, SNPs, Pathways
    Wikipedia http://en.wikipedia.org/wiki/Phosphoglycerate_kinase

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for PGK2 gene:
    Search GeneIP for patents involving PGK2

    GeneCards and IP:
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