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PGC Gene

protein-coding   GIFtS: 60
GCID: GC06M041704

Progastricsin (Pepsinogen C)

  See PGC-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Progastricsin (Pepsinogen C)1 2     gastricsin2
Pepsinogen C2 3     Pepsin C2
EC 3.4.23.33 8     Pepsinogen Group II2
PEPC2     preprogastricsin2
PGII2     EC 3.4.238

External Ids:    HGNC: 88901   Entrez Gene: 52252   Ensembl: ENSG000000960887   OMIM: 1697405   UniProtKB: P201423   

Export aliases for PGC gene to outside databases

Previous GC identifers: GC06M041706 GC06M041751 GC06M041813 GC06M041423


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for PGC Gene:
This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a
digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This
protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a
highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of
the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with
susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric
diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript
variants. A pseudogene of this gene is found on chromosome 1. (provided by RefSeq, Oct 2009)

GeneCards Summary for PGC Gene:
PGC (progastricsin (pepsinogen C)) is a protein-coding gene. Diseases associated with PGC include gastritis, and stomach cancer. GO annotations related to this gene include aspartic-type endopeptidase activity. An important paralog of this gene is BACE1.

UniProtKB/Swiss-Prot: PEPC_HUMAN, P20142
Function: Hydrolyzes a variety of proteins

Gene Wiki entry for PGC (Gastricsin) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000006.11  NC_018917.2  NT_007592.16  
Regulatory elements:
   Regulatory transcription factor binding sites in the PGC gene promoter:
         HOXA9B   C/EBPbeta   p53   p300   Brachyury   FOXD1   Meis-1b   MZF-1   CP2   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidPGC promoter sequence
   Search Chromatin IP Primers for PGC

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat PGC


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21.1   Ensembl cytogenetic band:  6p21.1   HGNC cytogenetic band: 6p21.1

PGC Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PGC gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M041704:  view genomic region     (about GC identifiers)

Start:
41,704,449 bp from pter      End:
41,721,847 bp from pter
Size:
17,399 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: PEPC_HUMAN, P20142 (See protein sequence)
Recommended Name: Gastricsin precursor  
Size: 388 amino acids; 42426 Da
Sequence caution: Sequence=AAA60062.1; Type=Erroneous initiation;
2 PDB 3D structures from and Proteopedia for PGC:
1AVF (3D)        1HTR (3D)    
Secondary accessions: B4DVZ3 Q5T3D7 Q5T3D8
Alternative splicing: 2 isoforms:  P20142-1   P20142-2   

Explore the universe of human proteins at neXtProt for PGC: NX_P20142

Explore proteomics data for PGC at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus
  • Selected DME Specific Peptides for PGC (P20142) (see all 19)
     NNRVGFA  RVGFATA  SLYTGQI  ILGDVFL 


    See PGC Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001159896.1  NP_002621.1  

    ENSEMBL proteins: 
     ENSP00000362116   ENSP00000349094   ENSP00000399429   ENSP00000405094  

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    Cloud-Clone Corp. Proteins for PGC

     
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    antibodies-online proteins for PGC (17 products) 

     
    Search antibodies-online for peptides for PGC

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    antibodies-online antibodies for PGC (69 products) 

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    antibodies-online kits for PGC (38 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    4 InterPro protein domains:
     IPR021109 Peptidase_aspartic_dom
     IPR001969 Aspartic_peptidase_AS
     IPR012848 Aspartic_peptidase_N
     IPR001461 Aspartic_peptidase

    Graphical View of Domain Structure for InterPro Entry P20142

    ProtoNet protein and cluster: P20142

    1 Blocks protein domain: IPB001461 Pepsin (A1) aspartic protease family signature

    UniProtKB/Swiss-Prot: PEPC_HUMAN, P20142
    Similarity: Belongs to the peptidase A1 family


    Find genes that share domains with PGC           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: PEPC_HUMAN, P20142
    Function: Hydrolyzes a variety of proteins
    Catalytic activity: More restricted specificity than pepsin A, but shows preferential cleavage at Tyr- -Xaa bonds.
    High activity on hemoglobin

         Genatlas biochemistry entry for PGC:
    progastricsin (pepsinogen C)

         Enzyme Numbers (IUBMB): EC 3.4.23.31 2 EC 3.4.232

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004190aspartic-type endopeptidase activity IEA--
         
    Find genes that share ontologies with PGC           About GenesLikeMe


    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for PGC

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    PEPC_HUMAN, P20142: Secreted
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    extracellular5
    nucleus4
    lysosome2
    plasma membrane2
    chloroplast1
    golgi apparatus1
    mitochondrion1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005615extracellular space TAS3335549
    GO:0005634nucleus ----
    GO:0005730nucleolus ----

    Find genes that share ontologies with PGC           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for PGC
    Interactions:

        Search GeneGlobe Interaction Network for PGC

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for PGC (P201423 ENSP000003621164) via UniProtKB, MINT, STRING, and/or I2D (see all 33)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CCNT1O605633, ENSP000002619004I2D: score=1 STRING: ENSP00000261900
    CDK9P507503, ENSP000003623614I2D: score=1 STRING: ENSP00000362361
    ESR1P033723, ENSP000002062494I2D: score=1 STRING: ENSP00000206249
    CAMPP499133I2D: score=1 
    SYVN1ENSP000003663954STRING: ENSP00000366395
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006508proteolysis TAS3335549
    GO:0007586digestion IEA--

    Find genes that share ontologies with PGC           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for PGC (PEPC)

    1 Novoseek inferred chemical compound relationship for PGC gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    pepsinogen 85.6 7 1455183 (5), 11922623 (2)



    Find genes that share compounds with PGC           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for PGC gene (2 alternative transcripts): 
    NM_001166424.1  NM_002630.3  

    Unigene Cluster for PGC:

    Progastricsin (pepsinogen C)
    Hs.1867  [show with all ESTs]
    Unigene Representative Sequence: BQ067503
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000373025(uc003ora.2) ENST00000356667 ENST00000415707 ENST00000425343(uc021yzm.1)

    miRNA
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    Additional mRNA sequence: 

    AK223274.1 AK301298.1 AK301325.1 BC042578.1 BC073740.1 J04443.1 U75272.1 

    3 DOTS entries:

    DT.97860858  DT.95096899  DT.121323448 

    Selected AceView cDNA sequences (see all 335):

    BM790643 BM768237 BM794529 BM756643 BM819885 BM852572 BM849061 BM769387 
    BM756688 AI270354 AI678999 BM769493 BM797473 BM756131 BM756758 BM789887 
    BM769368 BI490133 AI678651 BC073740 BM791128 BQ082621 BM970330 AI888430 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for PGC    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9
    SP1:                                                            
    SP2:                    -     -                                 


    ECgene alternative splicing isoforms for PGC

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    PGC expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGTGCTCTTC
    PGC Expression
    About this image


    PGC expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Stomach (Gastrointestinal Tract)    fully expand to see all 3 entries
             stomach 1 ; glandular cells   
             stomach cardiac   
     
     Lung (Respiratory System)
             Alveolar type II cells
     
     Adipose (Muscoskeletal System)
             HyStem+BMP4-induced 7SMOO32 cells
    PGC Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    PGC Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.1867
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for PGC gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Pgc1 , 5 progastricsin (pepsinogen C)1, 5 78.87(n)1
    74.81(a)1
      17 (23.98 cM)5
    1098201  NM_025973.31  NP_080249.21 
     477268425 
    chicken
    (Gallus gallus)
    Aves PGC1 progastricsin (pepsinogen C) 71.25(n)
    66.58(a)
      395690  NM_204877.2  NP_990208.1 
    lizard
    (Anolis carolinensis)
    Reptilia PGC6
    progastricsin (pepsinogen C)
    73(a)
    1 ↔ 1
    4(119561601-119577058)
    African clawed frog
    (Xenopus laevis)
    Amphibia pgc-A2 pepsinogen C 76.67(n)    AB045379.1 
    A. gossypii yeast
    (Ashbya gossypii)
    Saccharomycetes AGOS_ACR144W1 AGOS_ACR144W 50.75(n)
    40(a)
      4619678  NM_208899.1  NP_983546.1 


    ENSEMBL Gene Tree for PGC (if available)
    TreeFam Gene Tree for PGC (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for PGC gene
    BACE12  CTSD2  PGA32  BACE22  NAPSA2  CTSE2  PGA52  REN2  
    PGA42  
    7 SIMAP similar genes for PGC using alignment to 3 protein entries:     PEPC_HUMAN (see all proteins):
    PGA3    CTSE    PGA5    PGA4    REN    CTSD
    NAPSA

    Find genes that share paralogs with PGC           About GenesLikeMe


    2 Pseudogenes.org Pseudogenes for PGC
    PGOHUM00000244143 PGOHUM00000244144


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for PGC (see all 312)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs719541381,2
    C--41431562(+) TGTGT-/GCGCGCG 2 -- int10--------
    rs105575941,2
    C--41706003(+) ATATG-/CACACAC 1 -- int10--------
    rs349061551,2
    C--41706014(+) CACAC-/ACACACA 1 -- int11Minor allele frequency- AC:0.00NA 2
    rs58757701,2
    C--41706023(+) acacaC/Tataca 1 -- int10--------
    rs1932247501,2
    --41706132(+) AGGCCA/GAGGTA 1 -- int10--------
    rs23957851,2
    C--41706191(+) tgaaaT/Ccccgc 1 -- int13Minor allele frequency- C:0.00NA 6
    rs1446236791,2
    --41706292(+) GCCCAC/GGAGGC 1 -- int10--------
    rs1390044771,2
    --41706405(+) AAACAA/GCACAG 1 -- int10--------
    rs1845508581,2
    --41706414(+) AGATGC/GCTGGG 1 -- int10--------
    rs1508691541,2
    --41706520(+) TGAAAA/CCTCAT 1 -- int10--------

    HapMap Linkage Disequilibrium report for PGC (41704449 - 41721847 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for PGC:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2211967CNV Deletion18987734
    esv2731978CNV Deletion23290073
    esv2731977CNV Deletion23290073

    Human Gene Mutation Database (HGMD): PGC
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing PGC
    DNA2.0 Custom Variant and Variant Library Synthesis for PGC

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 169740    OMIM disorders: --

    2 diseases for PGC:    
    About MalaCards
    gastritis    stomach cancer

    3 diseases from the University of Copenhagen DISEASES database for PGC:
    Gastritis     Peptic ulcer     Stomach cancer

    Find genes that share disorders with PGC           About GenesLikeMe

    3 Novoseek inferred disease relationships for PGC gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    gastritis 45.5 1 1455183 (1)
    metastasis 0 3 2110593 (3)
    cancer 0 2 1455183 (1), 20231168 (1)

    Genetic Association Database (GAD): PGC
    Human Genome Epidemiology (HuGE) Navigator: PGC (12 documents)

    Export disorders for PGC gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for PGC gene, integrated from 10 sources (see all 81):
    (articles sorted by number of sources associating them with PGC)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Crystal and molecular structures of human progastricsin at 1.62-A resolution. (PubMed id 7714902)1, 2, 9 Moore S.A.... James M.N.G. (J. Mol. Biol. 1995)
    2. Structural characterization of activation 'intermediate 2' on the pathway to human gastricsin. (PubMed id 9406551)1, 2, 9 Khan A.R.... James M.N. (Nat. Struct. Biol. 1997)
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    4. [Correlation of pepsinogen C (PGC) gene insertion/deletion polymorphism to PGC protein expression in gastric mucosa and serum]. (PubMed id 19624876)1, 4 Sun L.P....Yuan Y. (Ai Zheng 2009)
    5. Impact of pepsinogen C polymorphism on individual susceptibility to gastric cancer and its precancerous conditions in a Northeast Chinese population. (PubMed id 19132389)1, 4 Sun L.P....Yuan Y. (J. Cancer Res. Clin. Oncol. 2009)
    6. Overall survival in women with breast cancer: the influence of pepsinogen C gene polymorphism. (PubMed id 18447628)1, 4 Pinto-Correia A.L....Medeiros R. (DNA Cell Biol. 2008)
    7. [Interaction between an insertion/deletion polymorphism in pepsinogen C and Helicobacter pylori infection in the development of gastric cancer]. (PubMed id 19173902)1, 4 Sun L.P....Yuan Y. (Zhonghua Zhong Liu Za Zhi 2008)
    8. Gastric cancer in a Caucasian population: role of pepsinogen C genetic variants. (PubMed id 16937501)1, 4 Pinto-Correia A.L....Dinis-Ribeiro M. (World J. Gastroenterol. 2006)
    9. [Correlation between an insertion-deletion polymorphism in the pepsinogen C gene and gastric cancer as well as its precursors]. (PubMed id 17288837)1, 4 Sun L.P....Yuan Y. (Zhonghua Yi Xue Za Zhi 2006)
    10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 5225 HGNC: 8890 AceView: PGC Ensembl:ENSG00000096088 euGenes: HUgn5225
    ECgene: PGC H-InvDB: PGC

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for PGC Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for PGC gene:
    Search GeneIP for patents involving PGC

    GeneCards and IP:
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