External Ids for PFN3 Gene
Previous GeneCards Identifiers for PFN3 Gene
The product of this gene belongs to the profilin family of proteins. This protein binds to actin and affects the structure of the cytoskeleton. It also may be involved in spermatogenesis. It is a single exon gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for PFN3 Gene
PFN3 (Profilin 3) is a Protein Coding gene. Among its related pathways are Salmonella infection (KEGG) and Shigellosis. GO annotations related to this gene include actin binding and lipid binding. An important paralog of this gene is PFN1.
UniProtKB/Swiss-Prot for PFN3 Gene
Binds to actin and affects the structure of the cytoskeleton. Slightly reduces actin polymerization. Binds to poly-L-proline, phosphatidylinositol 3-phosphate (PtdIns(3)P), phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) and phosphatidylinositol 4-phosphate (PtdIns(4)P). May be involved in spermatogenesis.