External Ids for PFDN2 Gene
Previous GeneCards Identifiers for PFDN2 Gene
This gene encodes a member of the prefoldin beta subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. [provided by RefSeq, Jul 2008]
GeneCards Summary for PFDN2 Gene
PFDN2 (Prefoldin Subunit 2) is a Protein Coding gene. Among its related pathways are Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding and Transport to the Golgi and subsequent modification. GO annotations related to this gene include unfolded protein binding and protein binding involved in protein folding.
UniProtKB/Swiss-Prot for PFDN2 Gene
Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.