PFAS Gene
protein-coding GIFtS: 61
GCID: GC17P008152
|
|
phosphoribosylformylglycinamidine synthase
| |
Aliases
for PFAS gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Phosphoribosylformylglycinamidine Synthase1 2 | | Formylglycinamide Ribotide Synthetase2 3 | | FGARAT1 2 3 5 | | FGAMS2 3 | | PURL1 2 | | FGAM Synthase2 3 | | KIAA03611 3 | | EC 6.3.5.33 8 | | Formylglycinamide Ribotide Amidotransferase2 3 | | FGAR Amidotransferase2 |
Export aliases for PFAS gene to outside databasesPrevious GC identifers: GC17U990074 GC17P009241 GC17P008099 GC17P008353 GC17P008093 GC17P008048 |
Summaries
for PFAS gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for PFAS:
Purines are necessary for many cellular processes, including DNA replication, transcription, and energy metabolism. Tenenzymatic steps are required to synthesize inosine monophosphate (IMP) in the de novo pathway of purine biosynthesis.The enzyme encoded by this gene catalyzes the fourth step of IMP biosynthesis. (provided by RefSeq, Jul 2008)
|
Genomic Views
for PFAS gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000017.10 NC_018928.1 NT_010718.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the PFAS gene promoter:
AML1a
Other transcription factors
Search SABiosciences Chromatin IP Primers for PFAS
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PFAS |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 17p13.1 Ensembl cytogenetic band: 17p13.1 HGNC cytogenetic band: 17p13.1PFAS Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17P008152: view genomic region
(about GC identifiers)
Start:
|
8,150,936 bp from pter |
End:
|
8,173,809 bp from pter |
Size:
|
22,874 bases |
Orientation:
|
plus strand |
|
Proteins
for PFAS gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: PUR4_HUMAN, O15067 (See
protein sequence)Recommended Name: Phosphoribosylformylglycinamidine synthase Size: 1338 amino acids; 144734 Da
Subcellular location: Cytoplasm (By similarity)
Sequence caution: Sequence=BAA20816.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: A6H8V8Explore the universe of human proteins at neXtProt for PFAS: NX_O15067
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O15067
4/8 DME Specific Peptides for PFAS (O15067) (see all 8)
PFAS Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_036525.1
ENSEMBL proteins: ENSP00000463362 ENSP00000464689 ENSP00000464671 ENSP00000313490 ENSP00000463045 ENSP00000462874 ENSP00000463103 ENSP00000443244 ENSP00000441706 Reactome Protein details: O15067
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
PFAS for ontologies About GeneDecksing
PFAS Antibody Products:
Assay Products for PFAS: |
Protein
Domains /
Families
for PFAS gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
PFAS for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry O15067ProtoNet protein and cluster: O15067 2 Blocks protein families: IPB000728 AIR synthase related protein IPB010918 AIR synthase related protein
UniProtKB/Swiss-Prot: PUR4_HUMAN, O15067Similarity: In the N-terminal section; belongs to the FGAMS familySimilarity: Contains 1 glutamine amidotransferase type-1 domain |
Function
for PFAS gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: PUR4_HUMAN, O15067Catalytic activity: ATP + N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide + L-glutamine + H(2)O = ADP + phosphate +2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine + L-glutamate Genatlas biochemistry entry for PFAS:formylglycineamide ribonucleotide amidotransferase,150kDa,FGAM synthetase,catalyzing the fourth step of the de novopurine biosynthesis,leading to formyl glycinamidine ribonucleotide (FGAM)
Enzyme Number (IUBMB): EC 6.3.5.31 2
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PFAS (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PFAS
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: PFAS (NM_012393) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for PFAS | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PFAS |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PFAS |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004642 | phosphoribosylformylglycinamidine synthase activity |
IDA | 10548741 | | GO:0005524 | ATP binding |
IEA | -- |
PFAS for ontologies About GeneDecksing
Animal Models:
3 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Pfas):
PFAS for phenotypes About GeneDecksing
|
Pathways & Interactions
for PFAS gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | purine nucleotides de novo biosynthesis II | | | 2 | Purine metabolism | | | 3 | Metabolism | | | 4 | Purine metabolism | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2  BioSystems Pathways for PFAS
4 
Reactome Pathways for PFAS
2 
Kegg Pathways (Kegg details for PFAS):
UniProtKB/Swiss-Prot: PUR4_HUMAN, O15067Pathway: Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole fromN(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 1/2
PFAS for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for PFAS
STRING Interaction
Network Preview (showing 5 interactants - click image to see 23)
5/81 Interacting proteins for PFAS (O150671, 3 ENSP000003134904) via UniProtKB, MINT, STRING, and/or I2D (see all 81)
| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| TNFRSF10D | Q9UBN61, 3, ENSP000003102634 | EBI-1052653,EBI-1044859 I2D:
score=2 STRING: ENSP00000310263 | | HLA-B | P304801, 3 | EBI-1052653,EBI-1054175 I2D:
score=1 I2D:
score=1 | | EPB41 | P111711, 3 | EBI-1052653,EBI-1050906 I2D:
score=2 | | MCC | P235081, 3 | EBI-1052653,EBI-307531 I2D:
score=2 | | TRAF6 | Q9Y4K31, 3 | EBI-1052653,EBI-359276 I2D:
score=2 |
About this table
Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006144 | purine nucleobase metabolic process |
TAS | -- | | GO:0006189 | 'de novo' IMP biosynthetic process |
NAS | 10548741 | | GO:0006541 | glutamine metabolic process |
IEA | -- | | GO:0009168 | purine ribonucleoside monophosphate biosynthetic process |
TAS | -- | | GO:0042493 | response to drug |
IEA | -- |
PFAS for ontologies About GeneDecksing
|
Drugs & Compounds
for PFAS gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
PFAS for compounds About GeneDecksing
 Browse Tocris compounds for PFAS
3 HMDB Compounds for PFAS About this table
2 DrugBank Compounds for PFAS About this table
3 Novoseek chemical compound relationships for PFAS gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| inosine monophosphate |
70.1 |
6 |
15566465 (1) |
| purine |
66.8 |
4 |
9328467 (1), 10548741 (1), 15566465 (1) |
| guanylate |
51.9 |
1 |
2347042 (1) |
Search CenterWatch for drugs/clinical trials and news about PFAS / PUR4
|
Transcripts
for PFAS gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for PFAS gene: NM_012393.2 Unigene Cluster for PFAS: Phosphoribosylformylglycinamidine synthase Hs.573976 [show with all ESTs]Unigene Representative Sequence: NM_01239312 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000585183 ENST00000584044 ENST00000580356 ENST00000314666(uc002gkr.3 uc010vuv.2 uc002gks.3)
ENST00000581242 ENST00000585319 ENST00000583059 ENST00000581288 ENST00000578979
ENST00000546020 ENST00000580251 ENST00000545834(uc010cnw.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PFAS (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PFAS
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: PFAS (NM_012393) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for PFAS | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PFAS |
Additional cDNA sequence: AB002359.1 AK292402.1 AK292804.1 AK295895.1 AY545554.1 BC006522.2 BC009318.2 BC063538.1 BC146768.1 BC167158.1 9 DOTS entries: DT.210405 DT.100778167 DT.102828379 DT.100744649 DT.100778165 DT.101981676 DT.121005380 DT.121005387 DT.100663545 24/97 AceView cDNA sequences (see all 97): BQ186094 CB991938 BC063538 CB128507 BG818824 CB123130 AI064852 AA593024 BQ427996 AI624181 AA393540 BQ216997 NM_012393 AL044325 CB991935 BQ065341 BM476397 BM834506 BQ216455 CB997531 BX452354 BX456770 BE271660 BP430750
GeneLoc Exon Structure
5/18 Alternative Splicing Database (ASD) splice patterns (SP) for PFAS (see all 18) About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3a | · | 3b | · | 3c | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b | ^ | 7a | · | 7b | ^ | 8a | · | 8b | · | 8c | ^ | 9 | ^ | 10a | · | 10b | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18a | · |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 18b | · | 18c | · | 18d | ^ | 19 | ^ | 20a | · | 20b | · | 20c | ^ | 21a | · | 21b | · | 21c | ^ | 22a | · | 22b | ^ | 23a | · | 23b | ^ | 24a | · | 24b | ^ | 25a | · | 25b | · | 25c | ^ | 26a | · | 26b | · | 26c | ^ | 27a | · | 27b | ^ | 28a | · | 28b | ^ |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 29a | · | 29b | ^ | 30 |
|---|
|
| SP1: | | | | | | | |
| SP2: | | | | | | | |
| SP3: | | | | | | | |
| SP4: | | | | | | | |
| SP5: | | | | | | |
ECgene alternative splicing isoforms for PFAS
|
Expression
for PFAS gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| PFAS expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TGTGAGGCAT
About this image
See PFAS Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for PFAS
SOURCE GeneReport for Unigene cluster: Hs.573976
SABiosciences Custom PCR Arrays for PFAS
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PFAS
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat PFAS | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PFAS | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PFAS | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PFAS |
Orthologs
for PFAS gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the last universal common ancestor (LUCA).
Orthologs for PFAS gene from 9/37 species (see all 37) About this table
ENSEMBL Gene Tree for PFAS (if available)
TreeFam Gene Tree for PFAS (if available) |
Paralogs
for PFAS gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for PFAS gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 17 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for PFAS (8150936 - 8173809 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for PFAS: --
Human Gene Mutation Database (HGMD): PFAS
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PFAS |
|
Disorders
/ Diseases
for PFAS gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
PFAS for disorders About GeneDecksing
OMIM gene information: 602133
OMIM disorders: --
11  diseases for PFAS: About MalaCardsalcohol-related neurodevelopmental disorder partial fetal alcohol syndrome fetal alcohol syndrome toxic megacolon
food allergy megacolon alcoholism down syndrome
pneumonia tuberculosis mycobacterium tuberculosis
4 diseases from the University of Copenhagen DISEASES database for PFAS:alcohol-related neurodevelopmental disorder Fetal alcohol syndrome Partial fetal alcohol syndrome Toxic megacolon Human Genome Epidemiology (HuGE) Navigator: PFAS (1 document)
Export disorders for PFAS gene to outside databases
|
Publications
for PFAS gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for PFAS gene, integrated from 9 sources (see all 36):
(articles sorted by number of sources associating them with PFAS) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Human phosphoribosylformylglycinamide amidotransferase (FGARAT): regional mapping, complete coding sequence, isolation of a functional genomic clone, and DNA sequence analysis. (PubMed id 10548741)1, 2, 9 Patterson D.... Bowersox J. (1999)
- Purification of, generation of monoclonal antibodies to, and mapping of phosphoribosyl N-formylglycinamide amidotransferase. (PubMed id 8110788)1, 3, 9 Barnes T.S....Patterson D. (1994)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
- Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9205841)1, 2 Nagase T.... Ohara O. (1997)
- The human GARS-AIRS-GART gene encodes two proteins which are differentially expressed during human brain development and temporally overexpressed in cerebellum of individuals with Down syndrome. (PubMed id 9328467)1, 9 Brodsky G....Patterson D. (1997)
- Oncolytic activity and mechanism of action of a novel L-cysteine derivative, L-cysteine, ethyl ester, S-(N-methylcarbamate) monohydrochloride. (PubMed id 2347042)7, 9 Jayaram H.N....Weber G. (1990)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
- Proteome-wide identification of ubiquitylation sites b y conjugation of engineered lysine-less ubiquitin. (PubMed id 22053931)1 Oshikawa K....Nakayama K.I. (2012)
|
External Searches for PFAS gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing PFAS gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing PFAS gene
(According to HUGE)
About This Section
| |
Specialized Databases showing PFAS gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for PFAS | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for PFAS gene:
Search GeneIP for patents involving PFAS
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for PFAS gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for PFAS | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for PFAS | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PFAS | | | OriGene Protein Over-expression Lysate for PFAS | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for PFAS | | OriGene 3'-UTR Clone for PFAS | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PFAS | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PFAS | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for PFAS | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for PFAS | | OriGene Custom Protein Services for PFAS | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat PFAS | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PFAS | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PFAS | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat PFAS | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PFAS | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PFAS |
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| | | | Search Tocris compounds for PFAS |
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 | | | PFAS Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PFAS |
|  |  |  | | | | ThermoFisher Antibody for PFAS |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PFAS |
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