Aliases for PFAS Gene
External Ids for PFAS Gene
Previous GeneCards Identifiers for PFAS Gene
Purines are necessary for many cellular processes, including DNA replication, transcription, and energy metabolism. Ten enzymatic steps are required to synthesize inosine monophosphate (IMP) in the de novo pathway of purine biosynthesis. The enzyme encoded by this gene catalyzes the fourth step of IMP biosynthesis. [provided by RefSeq, Jul 2008]
GeneCards Summary for PFAS Gene
PFAS (Phosphoribosylformylglycinamidine Synthase) is a Protein Coding gene. Diseases associated with PFAS include Alcohol-Related Neurodevelopmental Disorder and Partial Fetal Alcohol Syndrome. Among its related pathways are Purine metabolism (REACTOME) and Metabolism. GO annotations related to this gene include phosphoribosylformylglycinamidine synthase activity.
UniProtKB/Swiss-Prot for PFAS Gene
Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate (By similarity).