Aliases for PF4 Gene
Aliases for PF4 Gene
External Ids for PF4 Gene
- HGNC: 8861
- Entrez Gene: 5196
- Ensembl: ENSG00000163737
- OMIM: 173460
- UniProtKB: P02776
Previous GeneCards Identifiers for PF4 Gene
- GC04M074836
- GC04M075086
- GC04M075247
- GC04M075313
- GC04M075211
- GC04M070658
Summaries for PF4 Gene
-
This gene encodes a member of the CXC chemokine family. This chemokine is released from the alpha granules of activated platelets in the form of a homotetramer which has high affinity for heparin and is involved in platelet aggregation. This protein is chemotactic for numerous other cell type and also functions as an inhibitor of hematopoiesis, angiogenesis and T-cell function. The protein also exhibits antimicrobial activity against Plasmodium falciparum. [provided by RefSeq, Oct 2014]
GeneCards Summary for PF4 Gene
PF4 (Platelet Factor 4) is a Protein Coding gene. Diseases associated with PF4 include Thrombocytopenia and Erythromelalgia. Among its related pathways are Peptide ligand-binding receptors and ERK Signaling. GO annotations related to this gene include heparin binding and CXCR3 chemokine receptor binding. An important paralog of this gene is CXCL1.
UniProtKB/Swiss-Prot for PF4 Gene
-
Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation, the short form is a more potent inhibitor than the longer form.
No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PF4 Gene
Genomics for PF4 Gene
Regulatory Elements for PF4 Gene
Enhancers for PF4 Gene
| GeneHancer Identifier | Score | Enhancer Sources | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Other Gene Targets for Enhancer |
|---|
Enhancers around PF4 on UCSC Golden Path with GeneCards custom track
Promoters for PF4 Gene
| Ensembl Regulatory Elements (ENSRs) | TSS Distance (bp) | Size (bp) | Binding Sites for Transcription Factors within promoters |
|---|
ENSRs around PF4 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the PF4 gene promoter:
Regulatory Element Products
Genomic Location for PF4 Gene
- Chromosome:
- 4
- Start:
- 73,980,825 bp from pter
- End:
- 73,982,124 bp from pter
- Size:
- 1,300 bases
- Orientation:
- Minus strand
Genomic View for PF4 Gene
Genes around PF4 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 4q13.3 by Ensembl
- 4q12-q21 by Entrez Gene
- 4q12-q21 by HGNC
PF4 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for PF4 Gene
Proteins for PF4 Gene
-
Protein details for PF4 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P02776-PLF4_HUMAN
- Recommended name:
- Platelet factor 4
- Protein Accession:
- P02776
- Q53X61
- Q9UC64
- Q9UC65
Protein attributes for PF4 Gene
- Size:
- 101 amino acids
- Molecular mass:
- 10845 Da
- Quaternary structure:
-
- Homotetramer.
Protein Expression for PF4 Gene
Post-translational modifications for PF4 Gene
Other Protein References for PF4 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- EMD Millipore Complete listing of Mono and Polychlonal Antibodies for PF4
- R&D Systems Antibodies for PF4 (CXCL4/PF4)
- Novus Biologicals Antibodies for PF4
-
Cloud-Clone Corp. Antibodies for PF4
- Invitrogen Antibodies for PF4
- antibodies-online Antibodies for PF4: See all 114
- GeneTex PF4 antibody for PF4
-
Santa Cruz Biotechnology (SCBT) Antibodies for PF4
Protein Products
- R&D Systems Proteins and Enzymes for PF4 (CXCL4/PF4)
- Search Origene for MassSpec and Protein Over-expression Lysates for PF4
- Origene Custom Protein Services for PF4
- Sino Biological Recombinant Proteins for PF4
- Browse Sino Biological Cell Lysates
- ProSpec Recombinant Proteins for PF4
-
Cloud-Clone Corp. Proteins for PF4
- antibodies-online Proteins for PF4: See all 104
- Search antibodies-online for peptides
- GeneTex CXCL4 Recombinant Protein (Active) (GTX48162-PRO) for PF4
Assay Products
-
Custom Assay ServicesOriGene ELISA Kits for PF4
- R&D Systems ELISAs, Luminex Assays, Proteome Profiler Antibody Arrays, and other biochemical assays for PF4 (CXCL4/PF4)
- antibodies-online Kits for PF4: See all 87
No data available for DME Specific Peptides for PF4 Gene
Domains & Families for PF4 Gene
Protein Domains for PF4 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for PF4 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P02776- Family:
-
- Belongs to the intercrine alpha (chemokine CxC) family.
No data available for Gene Families for PF4 Gene
Function for PF4 Gene
Molecular function for PF4 Gene
- GENATLAS Biochemistry:
- platelet factor 4 (see IMC2@)
- UniProtKB/Swiss-Prot Function:
- Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation, the short form is a more potent inhibitor than the longer form.
Phenotypes for PF4 Gene
- MGI mutant phenotypes for PF4:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for PF4:
Animal Models for PF4 Gene
- MGI Knock Outs for PF4:
-
- Pf4 tm1Mako
Animal Model Products
-
Taconic Biosciences Mouse Models for PF4
-
ViGene Biosciences lentiviral particle packaged cDNA for PF4 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for PF4 gene
- Search ViGene Biosciences for PF4
CRISPR Products
-
OriGene CRISPR knockouts for PF4
-
Santa Cruz Biotechnology (SCBT) CRISPR for PF4
- GenScript: Design CRISPR guide RNA sequences for PF4
miRNA Products
- Search ViGene Biosciences for PF4
Clone Products
- OriGene clones in human for PF4
- OriGene ORF clones in human,mouse,rat for PF4
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for PF4
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Cell Line Products
-
ViGene Biosciences adenoviral particle packaged cDNA for PF4 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for PF4 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for PF4 gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , miRNA , Transcription Factor Targets and HOMER Transcription for PF4 Gene
Localization for PF4 Gene
Subcellular locations from UniProtKB/Swiss-Prot for PF4 Gene
- Secreted.
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| cytosol | 2 |
| plasma membrane | 2 |
| vacuole | 2 |
| cytoskeleton | 1 |
| lysosome | 1 |
No data available for Gene Ontology (GO) - Cellular Components for PF4 Gene
Pathways & Interactions for PF4 Gene
More details on SuperPathways for PF4| Superpath | Contained pathways | ||
|---|---|---|---|
| 1 | PEDF Induced Signaling |
.61
.47
|
|
| 2 | Peptide ligand-binding receptors | ||
| 3 | Platelet activation, signaling and aggregation |
.45
|
|
| 4 | ERK Signaling |
.61
|
|
| 5 | Signaling by GPCR |
Pathways by source for PF4 Gene
1 BioSystems pathway for PF4 Gene
15 Reactome pathways for PF4 Gene
2 KEGG pathways for PF4 Gene
1 R&D Systems pathway for PF4 Gene
17 Qiagen pathways for PF4 Gene
Interacting Proteins for PF4 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0002576 | platelet degranulation | TAS | -- |
| GO:0002690 | positive regulation of leukocyte chemotaxis | IBA | -- |
| GO:0006955 | immune response | IEA,IBA | -- |
| GO:0007596 | blood coagulation | TAS | -- |
| GO:0010628 | positive regulation of gene expression | IDA | 10666185 |
No data available for SIGNOR curated interactions for PF4 Gene
Drugs & Compounds for PF4 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Drotrecogin alfa | Approved, Investigational, Withdrawn | Pharma | Target | 0 |
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs |
|---|
Transcripts for PF4 Gene
mRNA/cDNA for PF4 Gene
- (2) REFSEQ mRNAs :
- (4) Additional mRNA sequences :
- (30) Selected AceView cDNA sequences:
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
-
OriGene CRISPR knockouts for PF4
-
Santa Cruz Biotechnology (SCBT) CRISPR for PF4
- GenScript: Design CRISPR guide RNA sequences for PF4
miRNA Products
- Search ViGene Biosciences for PF4
Clone Products
- OriGene clones in human for PF4
- OriGene ORF clones in human,mouse,rat for PF4
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for PF4
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Flow Cytometry Products
Expression for PF4 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Blood (Cardiovascular System)
- Definitive Hematopoietic Stem Cells Definitive Yolk Sac
- Megakaryocytes Hematopoietic Bone Marrow
- Hematopoietic Stem Cells Hematopoietic Bone Marrow
- Hematopoietic Bone Marrow
-
Bone (Muscoskeletal System)
- Mesenchymal Condensate Cells Zeugopod
- Bone Marrow
- Brain (Nervous System)
-
Yolk Sac (Extraembryonic Tissues)
- Definitive Hematopoietic Stem Cells Definitive Yolk Sac
-
Head Mesenchyme (Muscoskeletal System)
- Cranial Neural Crest Cells Branchial Arch 1
-
Neural Crest (Gastrulation Derivatives)
- Cranial Neural Crest Cells Branchial Arch 1
-
Limb (Muscoskeletal System)
- Mesenchymal Condensate Cells Zeugopod
-
Cartilage (Muscoskeletal System)
- Mesenchymal Condensate Cells Zeugopod
- Liver (Hepatobiliary System)
-
Spleen (Hematopoietic System)
mRNA differential expression in normal tissues according to GTEx for PF4 Gene
This gene is overexpressed in Whole Blood (x44.9) and Spleen (x4.4).
This gene is overexpressed in Platelet (55.6) and Serum (7.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for PF4 Gene
SOURCE GeneReport for Unigene cluster for PF4 Gene Hs.81564
Primer Products
-
OriGene qPCR primer pairs for PF4
-
OriGene qPCR primer pairs and template standards for PF4
No data available for mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for PF4 Gene
Orthologs for PF4 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| cow (Bos Taurus) |
Mammalia | PF4 35 |
|
||
| PF4 36 |
|
OneToMany | |||
| mouse (Mus musculus) |
Mammalia | Pf4 35 |
|
||
| Pf4 16 |
|
||||
| Pf4 36 |
|
OneToMany | |||
| chimpanzee (Pan troglodytes) |
Mammalia | PF4 35 |
|
||
| PF4 36 |
|
OneToOne | |||
| rat (Rattus norvegicus) |
Mammalia | Pf4 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | -- 36 |
|
OneToMany | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | -- 36 |
|
ManyToMany | |
| -- 36 |
|
ManyToMany | |||
| -- 36 |
|
ManyToMany | |||
| chicken (Gallus gallus) |
Aves | -- 36 |
|
OneToMany | |
| lizard (Anolis carolinensis) |
Reptilia | -- 36 |
|
OneToMany |
- Species with no ortholog for PF4:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- dog (Canis familiaris)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for PF4 Gene
(9) SIMAP similar genes for PF4 Gene using alignment to 1 proteins:
Variants for PF4 Gene
| SNP ID | Clin | Chr 04 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs4694 | -- | 73,981,270(-) | GGAAG(A/G)AAAAT | reference, synonymous-codon | |
| rs352004 | -- | 73,980,853(-) | TATTA(C/T)CTTTG | downstream-variant-500B, utr-variant-3-prime | |
| rs352005 | -- | 73,980,911(-) | ATTCA(C/T)GCATT | downstream-variant-500B, utr-variant-3-prime | |
| rs352006 | -- | 73,981,160(-) | TACTT(A/C/T)TTTTT | utr-variant-3-prime | |
| rs352007 | -- | 73,981,575(+) | GAGGA(C/G)GAGGG | intron-variant |
Residual Variation Intolerance Score:
47.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.49;
10.57% of all genes are more intolerant (likely to be disease-causing)
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for PF4 Gene
Disorders for PF4 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| thrombocytopenia |
|
|
| erythromelalgia |
|
|
| heparin-induced thrombocytopenia |
|
|
| blood platelet disease |
|
|
| myocardial infarction |
|
Search PF4 in MalaCards
View complete list of genes associated with diseases
Relevant External Links for PF4
No data available for UniProtKB/Swiss-Prot and Genatlas for PF4 Gene
Publications for PF4 Gene
- Structural and functional comparison of the genes for human platelet factor 4 and PF4alt. (PMID: 1695112) Eisman R. … Poncz M. (Blood 1990) 3 4 23 67
- Mediators of neutrophil recruitment in human abdominal aortic aneurysms. (PMID: 19201759) Houard X. … Michel J.B. (Cardiovasc. Res. 2009) 3 23
- Platelet factor 4 is highly upregulated in dendritic cells after severe trauma. (PMID: 19750196) Maier M. … Marzi I. (Mol. Med. 2009) 3 23
- Platelet-associated PF-4 as a biomarker of early tumor growth. (PMID: 17914028) Cervi D. … Klement G.L. (Blood 2008) 3 23
- Immune complexes formed following the binding of anti-platelet factor 4 (CXCL4) antibodies to CXCL4 stimulate human neutrophil activation and cell adhesion. (PMID: 18539895) Xiao Z. … Neelamegham S. (Blood 2008) 3 23
Products for PF4 Gene
- R&D Systems Antibodies for PF4 (CXCL4/PF4)
- R&D Systems Proteins and Enzymes for PF4 (CXCL4/PF4)
- R&D Systems ELISAs, Luminex Assays, Proteome Profiler Antibody Arrays, and other biochemical assays for PF4 (CXCL4/PF4)
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody Services
- Custom Assay ServicesOriGene ELISA Kits for PF4
- Search Origene for MassSpec and Protein Over-expression Lysates for PF4
- Origene Custom Protein Services for PF4
- Origene siRNA, shRNA, mouse_rna, rat_shrna, and RNAi products in human, mouse, rat for PF4
- Browse OriGene Inhibitory RNA Products For PF4
- OriGene qPCR primer pairs for PF4
- OriGene qPCR primer pairs and template standards for PF4
- OriGene CRISPR knockouts for PF4
- OriGene clones in human for PF4
- OriGene ORF clones in human,mouse,rat for PF4
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- GenScript: Next-day shipping cDNA clones in your preferred vector
- GenScript Custom Purified and Recombinant Proteins Services for PF4
- GenScript Custom Assay Services for PF4
- GenScript Custom overexpressing Cell Line Services for PF4
- GenScript: Design CRISPR guide RNA sequences for PF4
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for PF4
- Novus Biologicals Antibodies for PF4
- Novus Biologicals proteins and lysates for PF4
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- ProSpec Recombinant Proteins for PF4
- Cloud-Clone Corp. Antibodies for PF4
- Cloud-Clone Corp. Proteins for PF4
- Taconic Biosciences Mouse Models for PF4
- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
- antibodies-online Antibodies for PF4: See all 114
- antibodies-online Kits for PF4: See all 87
- antibodies-online Proteins for PF4: See all 104
- Search antibodies-online for peptides
- GeneTex PF4 antibody for PF4
- GeneTex CXCL4 Recombinant Protein (Active) (GTX48162-PRO) for PF4
- ViGene Biosciences adenoviral particle packaged cDNA for PF4 gene
- ViGene Biosciences lentiviral particle packaged cDNA for PF4 gene
- ViGene Biosciences lentiviral particle packaged cDNA for PF4 gene
- ViGene Biosciences ready-to-package AAV shRNAs for PF4 gene
- ViGene Biosciences ready-to-package AAV shRNAs for PF4 gene
- ViGene Biosciences ready-to-package AAV shRNAs for PF4 gene
- Search ViGene Biosciences for PF4
- Search ViGene Biosciences for PF4
- Santa Cruz Biotechnology (SCBT) Antibodies for PF4
- Search Santa Cruz Biotechnology (SCBT) for PF4 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for PF4
Sources for PF4 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) I2D
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) UniGene
- (28) AceView
- (29) RNAdb
- (30) ASD
- (31) ECgene
- (32) GeneAnnot
- (33) SAGE
- (34) SOURCE
- (35) HomoloGene
- (36) PanEnsembl
- (37) euGenes
- (38) SGD
- (39) FlyBase
- (40) WormBase
- (41) Pseudogene
- (42) DGV
- (43) dbSNP
- (44) HapMap
- (45) GenAtlas
- (46) GeneTests
- (47) HGMD
- (48) GAD
- (49) LSDB
- (50) BGMUT
- (51) HuGE
- (52) eBioscience
- (53) Atlas
- (54) Cell Signaling Technology
- (55) GenBank
- (56) H-invDB
- (57) HORDE
- (58) HUGE
- (59) IMGT
- (60) Leiden
- (61) MILLIPORE
- (62) miRBase
- (63) DME
- (64) Nature
- (65) NCBI
- (66) OriGene
- (67) PubMed
- (68) R&D Systems
- (69) Salk
- (70) TGDB
- (71) Tufts
- (72) YEDA
- (73) CROW21
- (74) Tocris
- (75) Abcam
- (76) Novus
- (77) ProSpec
- (78) Sino Biological
- (79) GenScript
- (80) Qiagen
- (81) Cloud-Clone Corp.
- (82) Enzo Life Sciences
- (83) OCA
- (84) Proteopedia
- (85) MOPED
- (86) SPIRE
- (87) neXtProt
- (88) Reactome
- (89) GeneGo (Thomson Reuters)
- (90) fRNAdb
- (91) DISEASES
- (92) SIMAP
- (93) GenomeRNAi
- (94) LifeMap
- (95) miRTarBase
- (96) MalaCards
- (97) Invitrogen
- (98) BitterDB
- (99) Vector BioLabs
- (100) ESI-BIO
- (101) RefSeq
- (102) BioSystems
- (103) MaxQB
- (104) IUPHAR
- (105) BioGPS
- (106) Illumina
- (107) COMPARTMENTS
- (108) HOMER
- (109) PaxDb
- (110) ApexBio
- (111) Addgene
- (112) Advanced Cell Diagnostics
- (113) antibodies-online
- (114) CYP
- (115) NONCODE
- (116) SwitchGear Genomics
- (117) TreeFam
- (118) PathCards
- (119) GeneReviews
- (120) GeneTex
- (121) Taconic Biosciences
- (122) GTEx
- (123) ProteomicsDB
- (124) SCBT
- (125) DGIdb
- (126) ClinicalTrials
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- (128) RVIS
- (129) SIGNOR
- (130) diseasecard
- (131) NIH Rare Diseases
- (132) Orphanet
- (133) UMLS
- (134) GTR
- (135) Disease Ontology
- (136) Genetics Home Reference
- (137) MeSH
- (138) MedlinePlus
- (139) CDC
- (140) NINDS
- (141) NCBI Bookshelf
- (142) ClinVar
- (143) Gene Damage Index
- (144) ViGene Biosciences
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- (146) UDN
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- (148) FANTOM5
- (149) ENCODE
- (150) ProSci
- (151) Horizon