PEX3 Gene
protein-coding GIFtS: 60
GCID: GC06P143772
|
|
peroxisomal biogenesis factor 3
| |
Aliases
for PEX3 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Peroxisomal Biogenesis Factor 31 2 | | Peroxin-33 | | Peroxisomal Assembly Protein PEX32 3 | | Transformation-Related Protein 182 | | PBD10A2 | | Peroxin-33 | | TRG182 | | |
Export aliases for PEX3 gene to outside databasesPrevious GC identifers: GC06P143395 GC06P143619 GC06P143752 GC06P143813 GC06P141335 |
Summaries
for PEX3 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for PEX3:
The product of this gene is involved in peroxisome biosynthesis and integrity. It assembles membrane vesicles beforethe matrix proteins are translocated. Peroxins (PEXs) are proteins that are essential for the assembly of functionalperoxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive,lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are aheterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in casesfalling into particular complementation groups. Although the clinical features of PBD patients vary, cells from allPBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle.Defects in this gene are a cause Zellweger syndrome (ZWS). (provided by RefSeq, Oct 2008)
UniProtKB/Swiss-Prot: PEX3_HUMAN, P56589Function: Involved in peroxisome biosynthesis and integrity. Assembles membrane vesicles before the matrix proteins aretranslocated. As a docking factor for PEX19, is necessary for the import of peroxisomal membrane proteins in theperoxisomes
Gene Wiki entry for PEX3
|
Genomic Views
for PEX3 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000006.11 NC_018917.1 NT_025741.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the PEX3 gene promoter:
GR Sox5 GR-beta FOXO3 LCR-F1 GATA-1 FOXO3b HFH-1 FOXO3a NF-kappaB1
Other transcription factors
Search SABiosciences Chromatin IP Primers for PEX3
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PEX3 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 6q24.2 Ensembl cytogenetic band: 6q24.2 HGNC cytogenetic band: 6q24.2PEX3 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 6 GeneLoc Exon Structure GeneLoc location for GC06P143772: view genomic region
(about GC identifiers)
Start:
|
143,771,918 bp from pter |
End:
|
143,811,753 bp from pter |
Size:
|
39,836 bases |
Orientation:
|
plus strand |
|
Proteins
for PEX3 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: PEX3_HUMAN, P56589 (See
protein sequence)Recommended Name: Peroxisomal biogenesis factor 3 Size: 373 amino acids; 42140 Da
Subunit: Interacts with PEX19
Subcellular location: Peroxisome membrane; Multi-pass membrane protein
2 PDB 3D structures from  and Proteopedia  for PEX3:3AJB (3D)
3MK4 (3D)
Secondary accessions: Q6FGP5Explore the universe of human proteins at neXtProt for PEX3: NX_P56589
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P56589
PEX3 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_003621.1
ENSEMBL proteins: ENSP00000356564 ENSP00000356563 Reactome Protein details: P56589
Human Recombinant Protein Products:
Gene Ontology (GO): 5/10 cellular component terms (GO ID links to tree view) (see all 10): About this table
PEX3 for ontologies About GeneDecksing
PEX3 Antibody Products:
Assay Products for PEX3: |
Protein
Domains /
Families
for PEX3 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
PEX3 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry P56589ProtoNet protein and cluster: P56589 1 Blocks protein family: IPB006966 Peroxin-3
UniProtKB/Swiss-Prot: PEX3_HUMAN, P56589Similarity: Belongs to the peroxin-3 family |
Function
for PEX3 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: PEX3_HUMAN, P56589Function: Involved in peroxisome biosynthesis and integrity. Assembles membrane vesicles before the matrix proteins aretranslocated. As a docking factor for PEX19, is necessary for the import of peroxisomal membrane proteins in theperoxisomes Genatlas biochemistry entry for PEX3:peroxin 3,peroxisomal biogenesis factor 3
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PEX3 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PEX3 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: PEX3 (NM_003630) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for PEX3 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PEX3 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PEX3 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
PEX3 for ontologies About GeneDecksing
2 GenomeRNAi human phenotypes for PEX3:
Animal Models:
9 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Pex3):
PEX3 for phenotypes About GeneDecksing
|
Pathways & Interactions
for PEX3 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | ABC-family proteins mediated transport | | | 2 | Peroxisome | | | 3 | SLC-mediated transmembrane transport | |
Pathway sources
See GeneCards unified pathways
Show all pathways
3 
Reactome Pathways for PEX3
1 
Kegg Pathway (Kegg details for PEX3):
PEX3 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for PEX3
STRING Interaction
Network Preview (showing 5 interactants - click image to see more details)
5/7 Interacting proteins for PEX3 (P565891, 2, 3 ENSP000003565634) via UniProtKB, MINT, STRING, and/or I2D (see all 7)About this table
Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table
PEX3 for ontologies About GeneDecksing
|
Drugs & Compounds
for PEX3 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for PEX3
Search CenterWatch for drugs/clinical trials and news about PEX3
|
Transcripts
for PEX3 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for PEX3 gene: NM_003630.2 Unigene Clusters for PEX3: Peroxisomal biogenesis factor 3 Hs.7277 [show with all ESTs], Hs.592832 [show with all ESTs]Unigene Representative Sequences: NM_003630, AK0235933 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000367592 ENST00000367591(uc011edx.1 uc003qjl.3) ENST00000585848
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PEX3 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PEX3 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: PEX3 (NM_003630) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for PEX3 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PEX3 |
Additional cDNA sequence: AK023593.1 6 DOTS entries: DT.100780842 DT.442523 DT.91841079 DT.96086351 DT.95372939 DT.91686944 24/140 AceView cDNA sequences (see all 140): BI826271 BQ215000 CA312993 CB161881 AA747440 AU137342 AW959982 BM927221 CA488806 AI215540 CN482988 BC015506 AI332675 AA305508 BX441390 BP368895 CB116371 CR615782 AK023593 CR542062 AL522735 BG618210 BM718377 CR621449
GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for PEX3 About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | · | 7c | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 |
|---|
|
| SP1: | | | | | | | | | | | | | - | | | | | | | | | | | | - | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | - | | | | - | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for PEX3
|
Expression
for PEX3 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| PEX3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ACTTGTTCCC
About this image
See PEX3 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for PEX3
SOURCE GeneReport for Unigene clusters: Hs.7277 Hs.592832
UniProtKB/Swiss-Prot: PEX3_HUMAN, P56589Tissue specificity: Found in all examined tissues
SABiosciences Custom PCR Arrays for PEX3
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PEX3
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat PEX3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PEX3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PEX3 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PEX3 |
Orthologs
for PEX3 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for PEX3 gene from 10/29 species (see all 29) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Pex31 , 5 |
peroxisomal biogenesis factor 31, 5 |
88.89(n)1
94.09(a)1 |
|
10 (4.89 cM)5
565351 NM_019961.31 NP_064345.11
135238475 |
chicken
(Gallus gallus) |
Aves |
PEX31 |
peroxisomal biogenesis factor 3 |
79.77(n)
85.91(a) |
|
421669 XM_419708.3 XP_419708.1 |
lizard
(Anolis carolinensis) |
Reptilia |
PEX36 |
-- |
82(a) |
1 ↔ 1 |
1(203878591-203896831) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.113352 |
Xenopus laevis transcribed sequence with weak similarity more |
73.57(n) |
|
AW635257.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
zgc563132 |
similar to peroxisomal biogenesis factor 3 |
74.59(n) |
|
393197 BC046066.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG68591 , 3 |
peroxisome organization and biogenesis3
CG68591 |
32(a)3
47.52(n)1
39.07(a)1 |
|
71B53
396521 NM_140496.21 NP_648753.11 |
worm
(Caenorhabditis elegans) |
Secernentea |
prx-36 |
PeRoXisome assembly factor family member (prx-3) |
21(a) |
1 ↔ 1 |
X(6110760-6112881) |
baker's yeast
(Saccharomyces cerevisiae) |
Saccharomycetes |
PEX31 |
Pex3p |
39.64(n)
24.36(a) |
|
851929 NP_010616.3 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
PEX3-11 |
peroxin-3 |
44.88(n)
31.31(a) |
|
821342 NM_112698.3 NP_566598.1 |
rice
(Oryza sativa) |
Liliopsida |
Os09g03143001 |
hypothetical protein |
45.96(n)
30.77(a) |
|
4346691 NM_001069374.1 NP_001062839.1 |
ENSEMBL Gene Tree for PEX3 (if available)
TreeFam Gene Tree for PEX3 (if available) |
Paralogs
for PEX3 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for PEX3 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 6 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for PEX3 (143771918 - 143811753 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for PEX3: --
Human Gene Mutation Database (HGMD): PEX3
Locus Specific Mutation Databases (LSDB): PEX3
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PEX3 |
|
Disorders
/ Diseases
for PEX3 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
PEX3 for disorders About GeneDecksing
OMIM gene information: 603164
OMIM disorders: 214100
UniProtKB/Swiss-Prot: PEX3_HUMAN, P56589
Defects in PEX3 are the cause of peroxisome biogenesis disorder complementation group 12 (PBD-CG12)[MIM:614882]; also known as PBD-CGG. PBD refers to a group of peroxisomal disorders arising from a failure of proteinimport into the peroxisomal membrane or matrix. The PBD group is comprised of four disorders: Zellweger syndrome(ZWS), neonatal adrenoleukodystrophy (NALD), infantile Refsum disease (IRD), and classical rhizomelic chondrodysplasiapunctata (RCDP). ZWS, NALD and IRD are distinct from RCDP and constitute a clinical continuum of overlappingphenotypes known as the Zellweger spectrum. The PBD group is genetically heterogeneous with at least 14 distinctgenetic groups as concluded from complementation studies Defects in PEX3 are a cause of peroxisome biogenesis disorder 10A (PBD10A) [MIM:614882]. A fatal peroxisomebiogenesis disorder characterized by dysmorphic facial features, hepatomegaly, ocular abnormalities, renal cysts,hearing impairment, profound psychomotor retardation, severe hypotonia and neonatal seizures. Death occurs within thefirst year of life
14  diseases for PEX3: About MalaCardsperoxisomal biogenesis disorder peroxisome biogenesis disorders peroxisome biogenesis factor zellweger syndrome
zellweger syndrome, complementation group g rhizomelic chondrodysplasia punctata chondrodysplasia punctata infantile refsum disease
zellweger syndrome spectrum neonatal adrenoleukodystrophy refsum disease chondrodysplasia
adrenoleukodystrophy hypotonia
4 diseases from the University of Copenhagen DISEASES database for PEX3:Zellweger syndrome Infantile refsum disease Adrenoleukodystrophy Rhizomelic chondrodysplasia punctata 1 Novoseek disease relationship for PEX3 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| zellweger syndrome |
90.4 |
6 |
10958759 (2), 10871277 (1), 10968777 (1), 10942428 (1) |
GeneTests: PEX3
Zellweger Syndrome Spectrum
Export disorders for PEX3 gene to outside databases
|
Publications
for PEX3 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for PEX3 gene, integrated from 9 sources (see all 41):
(articles sorted by number of sources associating them with PEX3) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Cloning and characterization of the gene encoding the human peroxisomal assembly protein Pex3p. (PubMed id 9657383)1, 2, 3 Kammerer S.... Roscher A.A. (1998)
- PEX3 functions as a PEX19 docking factor in the import of class I peroxisomal membrane proteins. (PubMed id 15007061)1, 2, 9 Fang Y.... Gould S.J. (2004)
- Defective peroxisome membrane synthesis due to mutations in human PEX3 causes Zellweger syndrome, complementation group G. (PubMed id 10958759)1, 2, 9 Muntau A.C.... Roscher A.A. (2000)
- Identification and characterization of the human peroxin PEX3. (PubMed id 10430017)1, 2, 9 Soukupova M.... Dodt G. (1999)
- The human PEX3 gene encoding a peroxisomal assembly protein: genomic organization, positional mapping, and mutation analysis in candidate phenotypes. (PubMed id 10679269)1, 2, 9 Muntau A.C....Kammerer S. (2000)
- The peroxin pex3p initiates membrane assembly in peroxisome biogenesis. (PubMed id 10848631)1, 2, 9 Ghaedi K.... Fujiki Y. (2000)
- Insights into peroxisome function from the structure of PEX3 in complex with a soluble fragment of PEX19. (PubMed id 20554521)1, 2 Schmidt F....Dodt G. (2010)
- Structural basis for docking of peroxisomal membrane protein carrier Pex19p onto its receptor Pex3p. (PubMed id 21102411)1, 2 Sato Y....Kato H. (2010)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (2003)
|
External Searches for PEX3 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing PEX3 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing PEX3 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing PEX3 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for PEX3 | Pharmacogenomics, SNPs, Pathways | | GeneReviews | http://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/PEX3 |
|
| | |
About This Section
| Patent Information for PEX3 gene:
Search GeneIP for patents involving PEX3
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for PEX3 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for PEX3 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for PEX3 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PEX3 | | | OriGene Protein Over-expression Lysate for PEX3 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for PEX3 | | OriGene 3'-UTR Clone for PEX3 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PEX3 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PEX3 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for PEX3 | | OriGene Custom Protein Services for PEX3 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat PEX3 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PEX3 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PEX3 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat PEX3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PEX3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PEX3 |
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| | | | Search Tocris compounds for PEX3 |
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 | | | PEX3 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PEX3 |
|  |  |  | | | | Search ThermoFisher Antibodies for PEX3 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PEX3 |
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