PEX16 Gene
protein-coding GIFtS: 56
GCID: GC11M045931
|
|
peroxisomal biogenesis factor 16
| |
Aliases
for PEX16 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Peroxisomal Biogenesis Factor 161 2 3 | | Peroxin-163 | | PBD8A2 | | Peroxisomal Membrane Protein PEX162 | | PBD8B2 | | Peroxisome Biogenesis Factor 162 | | Peroxin 162 | | Peroxin-163 |
Export aliases for PEX16 gene to outside databasesPrevious GC identifers: GC11M047715 GC11M046620 GC11M045962 GC11M045895 GC11M045887 GC11M045638 |
Summaries
for PEX16 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for PEX16:
The protein encoded by this gene is an integral peroxisomal membrane protein. An inactivating nonsense mutationlocalized to this gene was observed in a patient with Zellweger syndrome of the complementation group CGD/CG9.Expression of this gene product morphologically and biochemically restores the formation of new peroxisomes,suggesting a role in peroxisome organization and biogenesis. Alternative splicing has been observed for this gene andtwo variants have been described. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: PEX16_HUMAN, Q9Y5Y5Function: Required for peroxisome membrane biogenesis. May play a role in early stages of peroxisome assembly. Canrecruit other peroxisomal proteins, such as PEX3 and PMP34, to de novo peroxisomes derived from the endoplasmicreticulum (ER). May function as receptor for PEX3
Gene Wiki entry for PEX16
|
Genomic Views
for PEX16 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000011.9 NC_018922.1 NT_009237.18
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the PEX16 gene promoter:
AML1a E47 C/EBPalpha Gfi-1 CHOP-10 Egr-2 HFH-1 FOXJ2 (long isoform) c-Myb FOXJ2
Other transcription factors
Search SABiosciences Chromatin IP Primers for PEX16
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PEX16 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 11p11.2 Ensembl cytogenetic band: 11p11.2 HGNC cytogenetic band: 11pPEX16 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 11 GeneLoc Exon Structure GeneLoc location for GC11M045931: view genomic region
(about GC identifiers)
Start:
|
45,931,220 bp from pter |
End:
|
45,940,363 bp from pter |
Size:
|
9,144 bases |
Orientation:
|
minus strand |
|
Proteins
for PEX16 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: PEX16_HUMAN, Q9Y5Y5 (See
protein sequence)Recommended Name: Peroxisomal membrane protein PEX16 Size: 336 amino acids; 38629 Da
Subunit: Interacts with PEX19
Subcellular location: Peroxisome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane
Secondary accessions: Q9BWB9Alternative splicing: 2 isoforms: Q9Y5Y5-1 Q9Y5Y5-2 Explore the universe of human proteins at neXtProt for PEX16: NX_Q9Y5Y5
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9Y5Y5
PEX16 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_004804.1 NP_476515.1
ENSEMBL proteins: ENSP00000241041 ENSP00000368024 ENSP00000434654 ENSP00000433045 ENSP00000431309 ENSP00000431132 ENSP00000434060 ENSP00000432486
Human Recombinant Protein Products:
Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view): About this table
PEX16 for ontologies About GeneDecksing
PEX16 Antibody Products:
Assay Products for PEX16: |
Protein
Domains /
Families
for PEX16 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
PEX16 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q9Y5Y5ProtoNet protein and cluster: Q9Y5Y5 UniProtKB/Swiss-Prot: PEX16_HUMAN, Q9Y5Y5Similarity: Belongs to the peroxin-16 family |
Function
for PEX16 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: PEX16_HUMAN, Q9Y5Y5Function: Required for peroxisome membrane biogenesis. May play a role in early stages of peroxisome assembly. Canrecruit other peroxisomal proteins, such as PEX3 and PMP34, to de novo peroxisomes derived from the endoplasmicreticulum (ER). May function as receptor for PEX3
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PEX16 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PEX16 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): PEX16 (NM_057174) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for PEX16 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PEX16 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PEX16 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
PEX16 for ontologies About GeneDecksing
Animal Models:
1 MGI mutant phenotype (inferred from 1 allele ) (MGI details for Pex16):
PEX16 for phenotypes About GeneDecksing
|
Pathways & Interactions
for PEX16 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Peroxisome | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 
Kegg Pathway (Kegg details for PEX16):
PEX16 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for PEX16
STRING Interaction
Network Preview (showing 3 interactants - click image to see more details)
3 Interacting proteins for PEX16 (Q9Y5Y52, 3 ENSP000002410414) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 5/8 biological process terms (GO ID links to tree view) (see all 8): About this table
PEX16 for ontologies About GeneDecksing
|
Drugs & Compounds
for PEX16 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for PEX16
Search CenterWatch for drugs/clinical trials and news about PEX16
|
Transcripts
for PEX16 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for PEX16 gene (2 alternative transcripts): NM_004813.2 NM_057174.2 Unigene Cluster for PEX16: Peroxisomal biogenesis factor 16 Hs.100915 [show with all ESTs]Unigene Representative Sequence: NM_00481311 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000241041(uc001nbu.3 uc001nbt.3) ENST00000523721 ENST00000378750
ENST00000532681 ENST00000533151 ENST00000532554 ENST00000525192 ENST00000527371
ENST00000525229 ENST00000528674 ENST00000529030
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PEX16 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PEX16 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): PEX16 (NM_057174) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for PEX16 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PEX16 |
Additional cDNA sequence: AB016531.1 AF118240.1 BC000467.2 BC004356.1 10 DOTS entries: DT.308067 DT.435673 DT.120703248 DT.100813881 DT.120703253 DT.95123709 DT.100813880 DT.95350434 DT.97834613 DT.95107118 24/129 AceView cDNA sequences (see all 129): AI696154 CR619814 C20713 CR612893 AI393119 BM746616 BM708237 AW860381 BG490835 BX342400 NM_004813 CA428591 BE734215 AI949310 CD365851 AI654715 BI488790 BX428061 BM824541 BI196320 BU620858 BU856794 BX400683 BM727360
GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for PEX16 About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b | · | 12c |
|---|
|
| SP1: | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | - | | | | | | |
| SP3: | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for PEX16
|
Expression
for PEX16 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| PEX16 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GATTACTTGC
About this image
See PEX16 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for PEX16
SOURCE GeneReport for Unigene cluster: Hs.100915
SABiosciences Custom PCR Arrays for PEX16
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PEX16
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat PEX16 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PEX16 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PEX16 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PEX16 |
Orthologs
for PEX16 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for PEX16 gene from 8/25 species (see all 25) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Pex161 , 5 |
peroxisomal biogenesis factor 161, 5 |
86.9(n)1
91.07(a)1 |
|
2 (50.98 cM)5
186331 NM_145122.21 NP_660104.21
923746765 |
chicken
(Gallus gallus) |
Aves |
PEX161 |
peroxisomal biogenesis factor 16 |
72.39(n)
75.19(a) |
|
423201 XM_421125.2 XP_421125.3 |
lizard
(Anolis carolinensis) |
Reptilia |
PEX166 |
-- |
69(a) |
1 ↔ 1 |
1(47908713-47922794) |
tropical clawed frog
(Xenopus tropicalis) |
Amphibia |
Str.89672 |
Transcribed sequence with weak similarity to protein more |
75.05(n) |
|
142003109 |
zebrafish
(Danio rerio) |
Actinopterygii |
Dr.165942 |
Transcribed sequence with weak similarity to protein more |
73.43(n) |
|
57051516 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG39473
pex161 |
peroxisome organization and biogenesis3
peroxin 161 |
36(a)3
49.95(n)1
39.08(a)1 |
|
77E63
402931 NM_140995.31 NP_649252.11 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
ATPEX166 |
peroxin-16 |
19(a) |
1 ↔ 1 |
2(18823171-18825735) |
rice
(Oryza sativa) |
Liliopsida |
-- |
SSE1, putative, expressed |
19(a) |
1 ↔ 1 |
2(1213995-1218060) |
ENSEMBL Gene Tree for PEX16 (if available)
TreeFam Gene Tree for PEX16 (if available) |
Paralogs
for PEX16 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for PEX16 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 11 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for PEX16 (45931220 - 45940363 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for PEX16
2 CNVs: 48808 48807
Human Gene Mutation Database (HGMD): PEX16
Locus Specific Mutation Databases (LSDB): PEX16
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PEX16 |
|
Disorders
/ Diseases
for PEX16 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
PEX16 for disorders About GeneDecksing
OMIM gene information: 603360
OMIM disorders: --
UniProtKB/Swiss-Prot: PEX16_HUMAN, Q9Y5Y5
Defects in PEX16 are the cause of peroxisome biogenesis disorder complementation group 9 (PBD-CG9)[MIM:614876]; also known as PBD-CGD. PBD refers to a group of peroxisomal disorders arising from a failure of proteinimport into the peroxisomal membrane or matrix. The PBD group is comprised of four disorders: Zellweger syndrome(ZWS), neonatal adrenoleukodystrophy (NALD), infantile Refsum disease (IRD), and classical rhizomelic chondrodysplasiapunctata (RCDP). ZWS, NALD and IRD are distinct from RCDP and constitute a clinical continuum of overlappingphenotypes known as the Zellweger spectrum. The PBD group is genetically heterogeneous with at least 14 distinctgenetic groups as concluded from complementation studies Defects in PEX16 are a cause of peroxisome biogenesis disorder 8A (PBD8A) [MIM:614876]. A fatal peroxisomebiogenesis disorder belonging to the Zellweger disease spectrum and clinically characterized by severe neurologicdysfunction with profound psychomotor retardation, severe hypotonia and neonatal seizures, craniofacial abnormalities,liver dysfunction, and biochemically by the absence of peroxisomes. Additional features include cardiovascular andskeletal defects, renal cysts, ocular abnormalities, and hearing impairment. Most severely affected individuals withthe classic form of the disease (classic Zellweger syndrome) die within the first year of life
15  diseases for PEX16: About MalaCardsperoxisome biogenesis factor zellweger syndrome zellweger syndrome, complementation group 9 peroxisomal biogenesis disorder
peroxisome biogenesis disorders rhizomelic chondrodysplasia punctata chondrodysplasia punctata infantile refsum disease
zellweger syndrome spectrum neonatal adrenoleukodystrophy refsum disease chondrodysplasia
adrenoleukodystrophy hypotonia cholesterol
3 diseases from the University of Copenhagen DISEASES database for PEX16:Zellweger syndrome Rhizomelic chondrodysplasia punctata Infantile refsum disease 1 Novoseek disease relationship for PEX16 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| zellweger syndrome |
88.6 |
3 |
9837814 (1), 11890679 (1), 14680974 (1) |
GeneTests: PEX16
Zellweger Syndrome Spectrum
Export disorders for PEX16 gene to outside databases
|
Publications
for PEX16 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for PEX16 gene, integrated from 9 sources (see all 25):
(articles sorted by number of sources associating them with PEX16) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Peroxisome synthesis in the absence of preexisting peroxisomes. (PubMed id 9922452)1, 2, 3 South S.T. and Gould S.J. (1999)
- Mutation in PEX16 is causal in the peroxisome-deficient Zellweger syndrome of complementation group D. (PubMed id 9837814)1, 2, 9 Honsho M.... Fujiki Y. (1998)
- The origin and maintenance of mammalian peroxisomes involves a de novo PEX16-dependent pathway from the ER. (PubMed id 16717127)1, 2 Kim P.K....Lippincott-Schwartz J. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- PEX19 is a predominantly cytosolic chaperone and import receptor for class 1 peroxisomal membrane proteins. (PubMed id 14709540)1, 2 Jones J.M.... Gould S.J. (2004)
- The membrane biogenesis peroxin Pex16p. Topogenesis and functional roles in peroxisomal membrane assembly. (PubMed id 12223482)1, 2 Honsho M.... Fujiki Y. (2002)
- Human pex19p binds peroxisomal integral membrane proteins at regions distinct from their sorting sequences. (PubMed id 11390669)1, 2 Fransen M.... Van Veldhoven P.P. (2001)
- PEX19 binds multiple peroxisomal membrane proteins, is predominantly cytoplasmic, and is required for peroxisome membrane synthesis. (PubMed id 10704444)1, 2 Sacksteder K.A.... Gould S.J. (2000)
- A novel aberrant splicing mutation of the PEX16 gene in two patients with Zellweger syndrome. (PubMed id 11890679)1, 9 Shimozawa N....Kondo N. (2002)
- Sec16B is involved in the endoplasmic reticulum expor t of the peroxisomal membrane biogenesis factor peroxin 16 (Pex16) in mammalian cells. (PubMed id 21768384)1 Yonekawa S....Tani K. (2011)
|
External Searches for PEX16 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing PEX16 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing PEX16 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing PEX16 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for PEX16 | Pharmacogenomics, SNPs, Pathways | | GeneReviews | http://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/PEX16 |
|
| | |
About This Section
| Patent Information for PEX16 gene:
Search GeneIP for patents involving PEX16
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for PEX16 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for PEX16 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for PEX16 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PEX16 | | | OriGene Protein Over-expression Lysate for PEX16 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for PEX16 | | OriGene 3'-UTR Clone for PEX16 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PEX16 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PEX16 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for PEX16 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for PEX16 | | OriGene Custom Protein Services for PEX16 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat PEX16 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PEX16 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PEX16 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat PEX16 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PEX16 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PEX16 |
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| | | | Search Tocris compounds for PEX16 |
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 | | | PEX16 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PEX16 |
|  |  |  | | | | ThermoFisher Antibody for PEX16 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PEX16 |
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