Aliases for PERP Gene
External Ids for PERP Gene
Previous GeneCards Identifiers for PERP Gene
GeneCards Summary for PERP Gene
PERP (PERP, TP53 Apoptosis Effector) is a Protein Coding gene. Diseases associated with PERP include Uveal Melanoma. Among its related pathways are p53 Pathway (RnD) and Apoptotic Pathways in Synovial Fibroblasts. An important paralog of this gene is TMEM47.
UniProtKB/Swiss-Prot for PERP Gene
Component of intercellular desmosome junctions. Plays a role in stratified epithelial integrity and cell-cell adhesion by promoting desmosome assembly. Plays a role as an effector in the TP53-dependent apoptotic pathway (By similarity).