Aliases for PELO Gene
External Ids for PELO Gene
Previous GeneCards Identifiers for PELO Gene
This gene encodes a protein which contains a conserved nuclear localization signal. The encoded protein may have a role in spermatogenesis, cell cycle control, and in meiotic cell division. [provided by RefSeq, Jul 2008]
GeneCards Summary for PELO Gene
PELO (Pelota MRNA Surveillance And Ribosome Rescue Factor) is a Protein Coding gene. Among its related pathways are mRNA surveillance pathway and Focal Adhesion. GO annotations related to this gene include endonuclease activity.
UniProtKB/Swiss-Prot for PELO Gene
Required for normal chromosome segregation during cell division and genomic stability (By similarity). May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs. May have ribonuclease activity (Potential).