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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

PEAR1 Gene

protein-coding   GIFtS: 49
GCID: GC01P156865

Platelet Endothelial Aggregation Receptor 1

(Previous name: multiple EGF-like-domains 12)
(Previous symbol: MEGF12)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Platelet Endothelial Aggregation Receptor 11 2     Multiple Epidermal Growth Factor-Like Domains Protein 122 3
MEGF121 2 3     hPEAR12 3
Multiple EGF-Like-Domains 121 2     JEDI2
Multiple EGF-Like Domains Protein 122 3     

External Ids:    HGNC: 336311   Entrez Gene: 3750332   Ensembl: ENSG000001878007   OMIM: 6102785   UniProtKB: Q5VY433   

Export aliases for PEAR1 gene to outside databases

Previous GC identifers: GC01P153666 GC01P155130 GC01P128221


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for PEAR1 Gene:
PEAR1 is a platelet receptor that signals upon the formation of platelet-platelet contacts independent of platelet
activation and secondary to platelet aggregation (Nanda et al., 2005 (PubMed 15851471)).(supplied by OMIM, Mar
2008)

GeneCards Summary for PEAR1 Gene: 
PEAR1 (platelet endothelial aggregation receptor 1) is a protein-coding gene. Diseases associated with PEAR1 include dysentery, and endotheliitis. An important paralog of this gene is SCARF1.

UniProtKB/Swiss-Prot: PEAR1_HUMAN, Q5VY43
Function: When overexpressed, reduces the number of both early and late non-adherent myeloid progenitor cells (By
similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NT_004487.19  NC_018912.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the PEAR1 gene promoter:
         AML1a   GATA-3   p53   Olf-1   FOXD1   CUTL1   LCR-F1   NF-AT   HNF-4alpha1   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for PEAR1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PEAR1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q23.1   Ensembl cytogenetic band:  1q23.1   HGNC cytogenetic band: 1q23.1

PEAR1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PEAR1 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P156865:  view genomic region     (about GC identifiers)

Start:
156,863,490 bp from pter      End:
156,886,226 bp from pter
Size:
22,737 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: PEAR1_HUMAN, Q5VY43 (See protein sequence)
Recommended Name: Platelet endothelial aggregation receptor 1 precursor  
Size: 1037 amino acids; 110666 Da
Subunit: Interacts with SHC2 upon its aggregation-induced tyrosine phosphorylation
Subcellular location: Cell membrane; Single-pass membrane protein (Potential). Note=Detected on the cell surface
in resting platelets
Sequence caution: Sequence=BAB84947.1; Type=Frameshift; Positions=557;
Secondary accessions: Q8TEK2

Explore the universe of human proteins at neXtProt for PEAR1: NX_Q5VY43

Explore proteomics data for PEAR1 at MOPED 

Post-translational modifications:

  • UniProtKB: Phosphorylated in the intracellular domain on tyrosine residues (By similarity). Phosphorylated on tyrosine
    residues by SRC. Tyrosine phosphorylation is detected upon platelet aggregation stimulated by collagen, TRAP and
    thrombin and platelet-platelet contacts but not after platelet activation. Tyrosine phosphorylation enhanced its
    association with SHC1 and SHC2
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q5VY43

  • PEAR1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    PEAR1 Protein Expression
    REFSEQ proteins: NP_001073940.1  
    ENSEMBL proteins: 
     ENSP00000397870   ENSP00000344465   ENSP00000389742   ENSP00000292357  

    Human Recombinant Protein Products for PEAR1: 
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    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for PEAR1 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001891phagocytic cup IEA--
    GO:0016021integral to membrane IEA--

    PEAR1 for ontologies           About GeneDecksing



    PEAR1 Antibody Products: 
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    Assay Products for PEAR1: 
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    Cloud-Clone Corp. ELISAs for PEAR1 
    Cloud-Clone Corp. CLIAs for PEAR1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    4 InterPro protein domains:
     IPR000742 EG-like_dom
     IPR011489 EMI_domain
     IPR002049 EGF_laminin
     IPR013032 EGF-like_CS

    Graphical View of Domain Structure for InterPro Entry Q5VY43

    ProtoNet protein and cluster: Q5VY43

    1 Blocks protein domain: IPB011489 EMI

    UniProtKB/Swiss-Prot: PEAR1_HUMAN, Q5VY43
    Similarity: Belongs to the MEGF family
    Similarity: Contains 9 EGF-like domains
    Similarity: Contains 1 EMI domain


    PEAR1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: PEAR1_HUMAN, Q5VY43
    Function: When overexpressed, reduces the number of both early and late non-adherent myeloid progenitor cells (By
    similarity)

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    PEAR1 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for PEAR1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for PEAR1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for PEAR1 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for PEAR1 

    miRNA
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    8/11 QIAGEN miScript miRNA Assays for microRNAs that regulate PEAR1 (see all 11):
    hsa-miR-485-5p hsa-miR-1206 hsa-miR-24-1* hsa-miR-4268 hsa-miR-1291 hsa-miR-24-2* hsa-miR-221* hsa-miR-370
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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    Clone
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    OriGene ORF clones in mouse, rat for PEAR1
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PEAR1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for PEAR1

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    2 Interacting proteins for PEAR1 (ENSP000002923574) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RANBP10ENSP000003165894STRING: ENSP00000316589
    SNRNP200ENSP000003171234STRING: ENSP00000317123
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0043654recognition of apoptotic cell IEA--

    PEAR1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for PEAR1

    Search CenterWatch for drugs/clinical trials and news about PEAR1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for PEAR1 gene (2 alternative transcripts): 
    NM_001080471.1  NM_207369.1  

    Unigene Cluster for PEAR1:

    Platelet endothelial aggregation receptor 1
    Hs.142003  [show with all ESTs]
    Unigene Representative Sequence: NM_001080471
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000444016 ENST00000338302 ENST00000455314 ENST00000469390(uc001fqk.1)
    ENST00000482505 ENST00000465101 ENST00000292357(uc009wsl.1 uc001fqj.1)

    miRNA
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    8/11 QIAGEN miScript miRNA Assays for microRNAs that regulate PEAR1 (see all 11):
    hsa-miR-485-5p hsa-miR-1206 hsa-miR-24-1* hsa-miR-4268 hsa-miR-1291 hsa-miR-24-2* hsa-miR-221* hsa-miR-370
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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    OriGene ORF clones in mouse, rat for PEAR1
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    DNA2.0 Custom Codon Optimized Gene Synthesis Service for PEAR1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PEAR1
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                         Customized lentivirus expression plasmids for stable overexpression of PEAR1 
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PEAR1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PEAR1

    Additional mRNA sequence: 

    AK074121.1 AK098809.1 

    4 DOTS entries:

    DT.100747264  DT.421851  DT.100747265  DT.92034522 

    24/72 AceView cDNA sequences (see all 72):

    AI160078 AK074121 CR609390 AI123863 CR599082 AL040177 CB409465 BU785495 
    BG005293 AA515689 BU741416 BM724776 AA132043 BM989236 AW594288 BE502716 
    AW237134 AI697757 BX090671 AI625773 AW302445 AA437092 BX353460 N80839 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    PEAR1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AACCGCACCC
    PEAR1 Expression
    About this image


    See PEAR1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for PEAR1

    SOURCE GeneReport for Unigene cluster: Hs.142003

    UniProtKB/Swiss-Prot: PEAR1_HUMAN, Q5VY43
    Tissue specificity: Expressed in umbilical vein endothelial cells and platelets (at protein level). Expressed in
    heart, kidney, skeletal muscle, pancreas, ovary, breast, lung, brain cortex, hypothalamus, spinal cord, dorsal
    root ganglion, endothelial cells of umbilical cord artery and vein, megakaryocytes, osteoblasts, coronary muscle
    and erythroid cells. Weakly expressed in peripheral blood leukocytes and macrophages

        SABiosciences Custom PCR Arrays for PEAR1
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PEAR1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for PEAR1 gene from 6/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Pear11 , 5 platelet endothelial aggregation receptor 11, 5 84.09(n)1
    84.74(a)1
      3 (38.50 cM)5
    731821  NM_152799.21  NP_690012.21 
     877478905 
    chicken
    (Gallus gallus)
    Aves PEAR11 platelet endothelial aggregation receptor 1 64.5(n)
    57.3(a)
      100857779  XM_003642625.1  XP_003642673.1 
    lizard
    (Anolis carolinensis)
    Reptilia PEAR16
    --
    Uncharacterized protein
    55(a)
    44(a)
    1 ↔ 1
    possible ortholog
    GL343640.1(135964-174404)
    GL343921.1(27207-93585)
    zebrafish
    (Danio rerio)
    Actinopterygii pear11 platelet endothelial aggregation receptor 1 56.97(n)
    51.48(a)
      571812  XM_695441.4  XP_700533.4 
    fruit fly
    (Drosophila melanogaster)
    Insecta drpr6
    CG95726
    --
    31(a)
    18(a)
    1 ↔ many
    possible ortholog
    3L(1715595-1731107)
    X(20042157-20049547)
    worm
    (Caenorhabditis elegans)
    Secernentea ced-16
    Cell death abnormality protein 1
    27(a)
    1 → many
    I(11851343-11868105)


    ENSEMBL Gene Tree for PEAR1 (if available)
    TreeFam Gene Tree for PEAR1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for PEAR1 gene
    SCARF12  MEGF112  MEGF102  SCARF22  
    3 SIMAP similar genes for PEAR1 using alignment to 3 protein entries:     PEAR1_HUMAN (see all proteins):
    MEGF10    MEGF11    SCARF1

    PEAR1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/755 SNPs in PEAR1 are shown (see all 755)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs75481811,2
    C,F,H--156861531(+) tttatT/Cgtatg 1 -- us2k15Minor allele frequency- C:0.04NS EA WA 536
    rs1436383381,2
    --156861556(+) ATACAG/TTTGAG 1 -- us2k10--------
    rs29867161,2
    C,F,H--156861589(+) ATGATC/ACTGCT 1 -- us2k120Minor allele frequency- A:0.26NS EA NA WA CSA 1204
    rs753373131,2
    C,F--156861678(+) CAGACC/TTCGGT 1 -- us2k12Minor allele frequency- T:0.07WA 120
    rs1481199941,2
    --156861771(+) GAGCCC/TAGGAA 1 -- us2k10--------
    rs46610661,2
    C,A,H--156861808(+) gaaacA/Cccatc 1 -- us2k18Minor allele frequency- C:0.06NA WA CSA 16
    rs1822564751,2
    --156861839(+) TAGCCA/TGACGT 1 -- us2k10--------
    rs1456346271,2
    C--156861849(+) TGTGG-/GCGCGCG 1 -- us2k10--------
    rs115864611,2
    H--156861850(+) gtgggC/Ggcgcg 1 -- us2k10--------
    rs668633281,2
    C--156861855(+) CGCGC-/GCCTGT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for PEAR1 (156863490 - 156886226 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for PEAR1:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv831659CNV Loss17160897
    nsv831648CNV Loss17160897


    Human Gene Mutation Database (HGMD): PEAR1
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing PEAR1
    DNA2.0 Custom Variant and Variant Library Synthesis for PEAR1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 610278    OMIM disorders: --

    2 diseases for PEAR1:    About MalaCards
    dysentery    endotheliitis


    PEAR1 for disorders           About GeneDecksing

    Genetic Association Database (GAD): PEAR1
    Human Genome Epidemiology (HuGE) Navigator: PEAR1 (3 documents)

    Export disorders for PEAR1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for PEAR1 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with PEAR1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Platelet endothelial aggregation receptor 1 (PEAR1), a novel epidermal growth factor repeat-containing transmembrane receptor, participates in platelet contact-induced activation. (PubMed id 15851471)1, 2, 3, 9 Nanda N.... Hart M.J. (2005)
    2. A novel variant in the platelet endothelial aggregation receptor-1 gene is associated with increased platelet aggregability. (PubMed id 18511696)1, 4, 9 Herrera-Galeano J.E....Becker L.C. (2008)
    3. Genome-wide meta-analyses identifies seven loci assoc iated with platelet aggregation in response to agonists. (PubMed id 20526338)1, 4 Johnson A.D....Becker L.C. (2010)
    4. A functional genomics approach reveals novel quantitative trait loci associated with platelet signalling pathways. (PubMed id 19429868)1, 4 Jones C.I....Ouwehand W.H. (2009)
    5. PEAR1 attenuates megakaryopoiesis via control of the P I3K/PTEN pathway. (PubMed id 23667054)1 Kauskot A....Hoylaerts M.F. (2013)
    6. Identification of a specific intronic PEAR1 gene vari ant associated with greater platelet aggregability and protein expression. (PubMed id 21791418)1 Faraday N....Becker L.C. (2011)
    7. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)2 Gregory S.G.... Bentley D.R. (2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 375033 HGNC: 33631 AceView: FLJ00193 Ensembl:ENSG00000187800 euGenes: HUgn375033
    ECgene: PEAR1 H-InvDB: PEAR1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for PEAR1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for PEAR1 gene:
    Search GeneIP for patents involving PEAR1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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