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Aliases for PDZD9 Gene

Aliases for PDZD9 Gene

  • PDZ Domain Containing 9 2 3 5
  • C16orf65 3 4
  • PDZ Domain-Containing Protein C16orf65 3
  • Chromosome 16 Open Reading Frame 65 2

External Ids for PDZD9 Gene

Previous HGNC Symbols for PDZD9 Gene

  • C16orf65

Previous GeneCards Identifiers for PDZD9 Gene

  • GC16M020239

Summaries for PDZD9 Gene

GeneCards Summary for PDZD9 Gene

PDZD9 (PDZ Domain Containing 9) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PDZD9 Gene

Genomics for PDZD9 Gene

Regulatory Elements for PDZD9 Gene

Enhancers for PDZD9 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around PDZD9 on UCSC Golden Path with GeneCards custom track

Promoters for PDZD9 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around PDZD9 on UCSC Golden Path with GeneCards custom track

Genomic Location for PDZD9 Gene

Chromosome:
16
Start:
21,957,540 bp from pter
End:
22,001,127 bp from pter
Size:
43,588 bases
Orientation:
Minus strand

Genomic View for PDZD9 Gene

Genes around PDZD9 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
PDZD9 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PDZD9 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PDZD9 Gene

Proteins for PDZD9 Gene

  • Protein details for PDZD9 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8IXQ8-PDZD9_HUMAN
    Recommended name:
    PDZ domain-containing protein 9
    Protein Accession:
    Q8IXQ8
    Secondary Accessions:
    • F5GWW8

    Protein attributes for PDZD9 Gene

    Size:
    264 amino acids
    Molecular mass:
    29904 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for PDZD9 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for PDZD9 Gene

Proteomics data for PDZD9 Gene at MOPED

Post-translational modifications for PDZD9 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for PDZD9 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for PDZD9 Gene

Domains & Families for PDZD9 Gene

Gene Families for PDZD9 Gene

Protein Domains for PDZD9 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for PDZD9 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8IXQ8

UniProtKB/Swiss-Prot:

PDZD9_HUMAN :
  • Contains 1 PDZ (DHR) domain.
Domain:
  • Contains 1 PDZ (DHR) domain.
genes like me logo Genes that share domains with PDZD9: view

Function for PDZD9 Gene

genes like me logo Genes that share phenotypes with PDZD9: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for PDZD9 Gene

Localization for PDZD9 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for PDZD9 Gene COMPARTMENTS Subcellular localization image for PDZD9 gene
Compartment Confidence
cytosol 2
nucleus 2
cytoskeleton 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for PDZD9 Gene

Pathways & Interactions for PDZD9 Gene

SuperPathways for PDZD9 Gene

No Data Available

Interacting Proteins for PDZD9 Gene

Gene Ontology (GO) - Biological Process for PDZD9 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for PDZD9 Gene

Drugs & Compounds for PDZD9 Gene

No Compound Related Data Available

Transcripts for PDZD9 Gene

mRNA/cDNA for PDZD9 Gene

(6) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(13) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for PDZD9 Gene

PDZ domain containing 9:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for PDZD9 Gene

No ASD Table

Relevant External Links for PDZD9 Gene

GeneLoc Exon Structure for
PDZD9
ECgene alternative splicing isoforms for
PDZD9

Expression for PDZD9 Gene

mRNA expression in normal human tissues for PDZD9 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for PDZD9 Gene

This gene is overexpressed in Testis (x24.4).

Protein differential expression in normal tissues from HIPED for PDZD9 Gene

This gene is overexpressed in Monocytes (39.0) and Tlymphocyte (30.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for PDZD9 Gene



SOURCE GeneReport for Unigene cluster for PDZD9 Gene Hs.98244

genes like me logo Genes that share expression patterns with PDZD9: view

Protein tissue co-expression partners for PDZD9 Gene

- Elite partner

Primer Products

No data available for mRNA Expression by UniProt/SwissProt for PDZD9 Gene

Orthologs for PDZD9 Gene

This gene was present in the common ancestor of chordates.

Orthologs for PDZD9 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia PDZD9 35
  • 85.76 (n)
  • 79.69 (a)
PDZD9 36
  • 60 (a)
OneToOne
dog
(Canis familiaris)
Mammalia PDZD9 35
  • 85.52 (n)
  • 77.78 (a)
PDZD9 36
  • 50 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Pdzd9 35
  • 77.26 (n)
  • 71.35 (a)
Pdzd9 16
Pdzd9 36
  • 54 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia PDZD9 35
  • 98.99 (n)
  • 98.48 (a)
PDZD9 36
  • 100 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Pdzd9 35
  • 78.76 (n)
  • 70.47 (a)
oppossum
(Monodelphis domestica)
Mammalia PDZD9 36
  • 41 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia PDZD9 36
  • 44 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia PDZD9 36
  • 30 (a)
OneToOne
Species with no ortholog for PDZD9:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for PDZD9 Gene

ENSEMBL:
Gene Tree for PDZD9 (if available)
TreeFam:
Gene Tree for PDZD9 (if available)

Paralogs for PDZD9 Gene

No data available for Paralogs for PDZD9 Gene

Variants for PDZD9 Gene

Sequence variations from dbSNP and Humsavar for PDZD9 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs4392055 -- 21,986,513(+) CTGAG(C/T)AGGAT intron-variant
rs13331714 -- 21,997,123(+) tggcc(C/T)acatg intron-variant
rs4783437 -- 21,988,811(+) AATTA(A/C/T)GTATC intron-variant
rs9927436 -- 21,988,523(+) ATAAT(G/T)GTCAC intron-variant
rs61735141 -- 21,984,481(+) TAGTA(G/T)GGTTC nc-transcript-variant, reference, missense

Structural Variations from Database of Genomic Variants (DGV) for PDZD9 Gene

Variant ID Type Subtype PubMed ID
esv34235 CNV Gain 17911159
nsv428322 CNV Gain 18775914
esv34544 CNV Gain 17911159
nsv7280 OTHER Inversion 18451855
dgv3n1 OTHER Inversion 15895083
nsv511047 OTHER Inversion 20534489
dgv47n16 OTHER Inversion 17901297
nsv499139 OTHER Inversion 21111241
esv998989 OTHER Inversion 20482838
esv2714070 CNV Deletion 23290073
dgv48n16 CNV Insertion 17901297
nsv1764 CNV Loss 18451855
nsv435668 CNV Deletion 17901297
nsv498860 CNV Loss 21111241
dgv2647n71 CNV Loss 21882294
nsv905598 CNV Gain 21882294
nsv519813 CNV Gain+Loss 19592680

Variation tolerance for PDZD9 Gene

Residual Variation Intolerance Score: 54.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.22; 24.45% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for PDZD9 Gene

Disorders for PDZD9 Gene

Relevant External Links for PDZD9

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
PDZD9

No disorders were found for PDZD9 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for PDZD9 Gene

Publications for PDZD9 Gene

  1. The sequence and analysis of duplication-rich human chromosome 16. (PMID: 15616553) Martin J. … Pennacchio L.A. (Nature 2004) 3 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 3
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3

Products for PDZD9 Gene

Sources for PDZD9 Gene

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