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Aliases for PDZD9 Gene

Aliases for PDZD9 Gene

  • PDZ Domain Containing 9 2 3 5
  • C16orf65 3 4
  • PDZ Domain-Containing Protein C16orf65 3
  • Chromosome 16 Open Reading Frame 65 2
  • PDZ Domain-Containing Protein 9 3

External Ids for PDZD9 Gene

Previous HGNC Symbols for PDZD9 Gene

  • C16orf65

Previous GeneCards Identifiers for PDZD9 Gene

  • GC16M020239

Summaries for PDZD9 Gene

GeneCards Summary for PDZD9 Gene

PDZD9 (PDZ Domain Containing 9) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PDZD9 Gene

Genomics for PDZD9 Gene

Regulatory Elements for PDZD9 Gene

Enhancers for PDZD9 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH16F022187 1.9 FANTOM5 Ensembl ENCODE 18.3 -191.1 -191078 9.2 MLX CREB3L1 ZFP64 YBX1 FEZF1 DMAP1 YY1 SLC30A9 ZNF416 ZNF143 MFSD13B SMG1P1 POLR3E NPIPB5 C16orf52 PDZD9 ENSG00000260635 SMG1P4 UQCRC2 ENSG00000260973
GH16F022351 1.5 FANTOM5 Ensembl ENCODE 9.3 -353.0 -352972 4.8 HDGF PKNOX1 ATF1 ARID4B FEZF1 FOS JUNB MIER2 TBX21 PPARG CDR2 POLR3E PDZD9 ENSG00000260635 GC16M022309
GH16F022029 1.1 Ensembl ENCODE 12 -28.7 -28733 1.7 SOX13 ELF3 ZNF792 CEBPG TEAD3 NR2F6 CREM HOMEZ ZNF652 MIXL1 PDZD9 SDR42E2 VWA3A GC16P022032 GC16P022022
GH16F022024 1.1 Ensembl ENCODE 11.9 -25.6 -25608 4.3 INSM2 RARA ZNF121 SCRT2 FOS SP5 JUNB TBX21 ZSCAN16 ETV4 PDZD9 SDR42E2 VWA3A RRN3P1 ENSG00000260306 NPIPB5 GC16P022022 GC16P022032
GH16F022098 1.1 Ensembl ENCODE 11.5 -98.0 -97952 0.6 ELF3 PKNOX1 ARID4B RAD21 RFX5 ZNF121 ZNF143 KLF11 ZNF362 ZNF654 SDR42E2 PDZD9 GC16P022106 PIR50524 LOC105371129
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around PDZD9 on UCSC Golden Path with GeneCards custom track

Genomic Location for PDZD9 Gene

21,957,540 bp from pter
22,001,127 bp from pter
43,588 bases
Minus strand

Genomic View for PDZD9 Gene

Genes around PDZD9 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
PDZD9 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PDZD9 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PDZD9 Gene

Proteins for PDZD9 Gene

  • Protein details for PDZD9 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    PDZ domain-containing protein 9
    Protein Accession:
    Secondary Accessions:
    • F5GWW8

    Protein attributes for PDZD9 Gene

    264 amino acids
    Molecular mass:
    29904 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for PDZD9 Gene


neXtProt entry for PDZD9 Gene

Post-translational modifications for PDZD9 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for PDZD9 Gene

No data available for DME Specific Peptides for PDZD9 Gene

Domains & Families for PDZD9 Gene

Gene Families for PDZD9 Gene

Protein Domains for PDZD9 Gene


Suggested Antigen Peptide Sequences for PDZD9 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 PDZ (DHR) domain.
  • Contains 1 PDZ (DHR) domain.
genes like me logo Genes that share domains with PDZD9: view

Function for PDZD9 Gene

genes like me logo Genes that share phenotypes with PDZD9: view

Animal Model Products

Inhibitory RNA Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for PDZD9 Gene

Localization for PDZD9 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for PDZD9 gene
Compartment Confidence
nucleus 2
cytosol 2
cytoskeleton 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for PDZD9 Gene

Pathways & Interactions for PDZD9 Gene

SuperPathways for PDZD9 Gene

No Data Available

Interacting Proteins for PDZD9 Gene

Selected Interacting proteins: Q8IXQ8-PDZD9_HUMAN for PDZD9 Gene via IID

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for PDZD9 Gene


No data available for Pathways by source and SIGNOR curated interactions for PDZD9 Gene

Transcripts for PDZD9 Gene

mRNA/cDNA for PDZD9 Gene

(5) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(13) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for PDZD9 Gene

PDZ domain containing 9:
Representative Sequences:

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for PDZD9 Gene

No ASD Table

Relevant External Links for PDZD9 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for PDZD9 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for PDZD9 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for PDZD9 Gene

This gene is overexpressed in Testis (x24.4).

Protein differential expression in normal tissues from HIPED for PDZD9 Gene

This gene is overexpressed in Monocytes (39.0) and Tlymphocyte (30.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for PDZD9 Gene

Protein tissue co-expression partners for PDZD9 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of PDZD9 Gene:


SOURCE GeneReport for Unigene cluster for PDZD9 Gene:

genes like me logo Genes that share expression patterns with PDZD9: view

Primer Products

No data available for mRNA Expression by UniProt/SwissProt for PDZD9 Gene

Orthologs for PDZD9 Gene

This gene was present in the common ancestor of chordates.

Orthologs for PDZD9 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia PDZD9 34 35
  • 98.99 (n)
(Bos Taurus)
Mammalia PDZD9 34 35
  • 85.76 (n)
(Canis familiaris)
Mammalia PDZD9 34 35
  • 85.52 (n)
(Rattus norvegicus)
Mammalia Pdzd9 34
  • 78.76 (n)
(Mus musculus)
Mammalia Pdzd9 34 16 35
  • 77.26 (n)
(Ornithorhynchus anatinus)
Mammalia PDZD9 35
  • 44 (a)
(Monodelphis domestica)
Mammalia PDZD9 35
  • 41 (a)
(Anolis carolinensis)
Reptilia PDZD9 35
  • 30 (a)
Species where no ortholog for PDZD9 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for PDZD9 Gene

Gene Tree for PDZD9 (if available)
Gene Tree for PDZD9 (if available)

Paralogs for PDZD9 Gene

No data available for Paralogs for PDZD9 Gene

Variants for PDZD9 Gene

Sequence variations from dbSNP and Humsavar for PDZD9 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs374661051 Pathogenic 21,965,440(+) CTTAC(A/C/T)GGAAT intron-variant, reference, synonymous-codon, missense
rs10521119 -- 21,971,873(+) AACCA(A/G)TGGTG intron-variant
rs10611346 -- 22,000,873(+) ATGAT(-/GATGAT)AATGA intron-variant
rs1064575 -- 21,980,290(+) TGGAC(C/T)CACAA intron-variant
rs111302989 -- 21,959,106(+) CTGAT(C/G)AAGGT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for PDZD9 Gene

Variant ID Type Subtype PubMed ID
esv34235 CNV gain 17911159
esv34544 CNV gain 17911159
esv3638193 CNV gain 21293372
esv998989 OTHER inversion 20482838
nsv1048054 CNV gain 25217958
nsv1077770 OTHER inversion 25765185
nsv1140248 OTHER inversion 24896259
nsv428322 CNV gain 18775914
nsv499139 OTHER inversion 21111241
nsv7280 OTHER inversion 18451855
esv3368991 OTHER inversion 20981092
dgv47n16 OTHER inversion 17901297
dgv3n1 OTHER inversion 15895083

Variation tolerance for PDZD9 Gene

Residual Variation Intolerance Score: 54.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.22; 24.45% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for PDZD9 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for PDZD9 Gene

Disorders for PDZD9 Gene

Relevant External Links for PDZD9

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for PDZD9 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for PDZD9 Gene

Publications for PDZD9 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  2. The sequence and analysis of duplication-rich human chromosome 16. (PMID: 15616553) Martin J. … Pennacchio L.A. (Nature 2004) 3 4 64
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 64
  4. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 3 64

Products for PDZD9 Gene

Sources for PDZD9 Gene

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