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PDZD4 Gene

protein-coding   GIFtS: 51
GCID: GC0XM153067

PDZ Domain Containing 4


(Previous symbol: PDZK4)
  Search for PDZD4
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
PDZ Domain Containing 41 2     LU12 5
PDZK41 2 3 5     KIAA14443 5
PDZRN4L2 3 5     PDZ Domain-Containing Protein 42
PDZ Domain-Containing RING Finger Protein 4-Like Protein2 3     

External Ids:    HGNC: 211671   Entrez Gene: 575952   Ensembl: ENSG000000678407   OMIM: 3006345   UniProtKB: Q76G193   
ORGUL members:         

Export aliases for PDZD4 gene to outside databases

Previous GC identifers: GC0XM152589 GC0XM152720 GC0XM141724


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for PDZD4 Gene:
PDZD4 (PDZ domain containing 4) is a protein-coding gene. An important paralog of this gene is PDZRN4.

Gene Wiki entry for PDZD4 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000023.11  NC_018934.2  NT_011681.17  
Regulatory elements:
   Regulatory transcription factor binding sites in the PDZD4 gene promoter:
         c-Fos   AML1a   AP-1   ATF-2   RelA   POU6F1 (c2)   NF-kappaB   CRE-BP1   c-Jun   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidPDZD4 promoter sequence
   Search Chromatin IP Primers for PDZD4

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat PDZD4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq28   Ensembl cytogenetic band:  Xq28   HGNC cytogenetic band: Xq28

PDZD4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PDZD4 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XM153067:  view genomic region     (about GC identifiers)

Start:
153,067,621 bp from pter      End:
153,096,020 bp from pter
Size:
28,400 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: PDZD4_HUMAN, Q76G19 (See protein sequence)
Recommended Name: PDZ domain-containing protein 4  
Size: 769 amino acids; 86171 Da
Sequence caution: Sequence=BAC03666.1; Type=Erroneous initiation;
Secondary accessions: B3KXB1 Q8NB75 Q9BUH9 Q9P284

Explore the universe of human proteins at neXtProt for PDZD4: NX_Q76G19

Explore proteomics data for PDZD4 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See PDZD4 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_115901.2  
    ENSEMBL proteins: 
     ENSP00000164640   ENSP00000476940   ENSP00000442033   ENSP00000377355  

    PDZD4 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for PDZD4

     
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR001478 PDZ

    Graphical View of Domain Structure for InterPro Entry Q76G19

    ProtoNet protein and cluster: Q76G19

    UniProtKB/Swiss-Prot: PDZD4_HUMAN, Q76G19
    Similarity: Contains 1 PDZ (DHR) domain


    Find genes that share domains with PDZD4           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    Find genes that share ontologies with PDZD4           About GenesLikeMe


    Phenotypes:
         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Pdzd4):
     normal 

    Find genes that share phenotypes with PDZD4           About GenesLikeMe

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for PDZD4
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for PDZD4

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for PDZD4
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for PDZD4

    miRNA
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    miRTarBase miRNAs that target PDZD4:
    hsa-mir-335-5p (MIRT018281)

    Block miRNA regulation of human, mouse, rat PDZD4 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate PDZD4 (see all 24):
    hsa-miR-642a hsa-miR-3194-5p hsa-miR-346 hsa-miR-218 hsa-miR-339-5p hsa-miR-558 hsa-miR-28-5p hsa-miR-1252
    SwitchGear 3'UTR luciferase reporter plasmidPDZD4 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for PDZD4
    Predesigned siRNA for gene silencing in human, mouse, rat PDZD4

    Gene Editing
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    Clone
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    GenScript: all cDNA clones in your preferred vector: PDZD4 (NM_032512)
    Browse Sino Biological Human cDNA Clones
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PDZD4

    Cell Line
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PDZD4


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    PDZD4_HUMAN, Q76G19: Cytoplasm, cell cortex. Note=Mainly localized under the plasma membrane
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    nucleus2
    mitochondrion1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005938cell cortex IEA--

    Find genes that share ontologies with PDZD4           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for PDZD4
    Interactions:

        Search GeneGlobe Interaction Network for PDZD4

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    Selected Interacting proteins for PDZD4 (Q76G192, 3 ENSP000001646404) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    GFI1BQ5VTD92, 3, ENSP000003447824MINT-2875350 I2D: score=3 STRING: ENSP00000344782
    KCNMA1Q127913, ENSP000002866274I2D: score=2 STRING: ENSP00000286627
    AP3M1Q9Y2T23I2D: score=5 
    HOOK3Q86VS83I2D: score=5 
    BMPR2ENSP000003637084STRING: ENSP00000363708
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for PDZD4



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for PDZD4 gene: 
    NM_032512.2  

    Unigene Cluster for PDZD4:

    PDZ domain containing 4
    Hs.92732  [show with all ESTs]
    Unigene Representative Sequence: AK127016
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000164640(uc004fiz.1 uc004fix.2 uc004fja.1 uc011mze.1)
    ENST00000484792 ENST00000475140 ENST00000483693 ENST00000480418 ENST00000480650
    ENST00000468491 ENST00000544474 ENST00000393758(uc004fiy.1)
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat PDZD4 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate PDZD4 (see all 24):
    hsa-miR-642a hsa-miR-3194-5p hsa-miR-346 hsa-miR-218 hsa-miR-339-5p hsa-miR-558 hsa-miR-28-5p hsa-miR-1252
    SwitchGear 3'UTR luciferase reporter plasmidPDZD4 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for PDZD4
    Predesigned siRNA for gene silencing in human, mouse, rat PDZD4
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: PDZD4 (NM_032512)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PDZD4
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for PDZD4
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat PDZD4
      QuantiTect SYBR Green Assays in human, mouse, rat PDZD4
      QuantiFast Probe-based Assays in human, mouse, rat PDZD4

    Additional mRNA sequence: 

    AB040877.1 AB103478.1 AF085862.1 AK091444.1 AK123229.1 AK123822.1 AK127016.1 AK309212.1 
    BC002606.2 BC008599.1 BC020347.1 BC080584.1 BC117277.1 BC143459.1 BC143542.1 BC143545.1 

    14 DOTS entries:

    DT.95374705  DT.313530  DT.101984196  DT.95374711  DT.91961008  DT.100807590  DT.100775165  DT.99971092 
    DT.100854832  DT.95374700  DT.121309357  DT.91829470  DT.95105543  DT.95374709 

    Selected AceView cDNA sequences (see all 87):

    CR606934 AI383598 AI004734 BM986853 AI624996 AF085862 BC080584 AK127016 
    AI383667 BC002606 AB103478 AX746986 BM926863 T23684 BM722836 BM664003 
    BC008599 CA433500 BI755020 AA349941 BQ637476 AK091444 NM_032512 AI391689 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for PDZD4 (see all 13)    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b · 2c ^ 3a · 3b · 3c ^ 4a · 4b · 4c · 4d · 4e ^ 5 ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9 ^ 10 ^ 11 ^ 12a · 12b
    SP1:              -     -     -     -     -     -           -     -     -     -     -     -     -           -                                       
    SP2:                                -     -     -                 -     -     -     -     -     -           -                                       
    SP3:                                -     -     -           -     -     -     -     -     -     -           -                                       
    SP4:                                                                                                                                                
    SP5:                                                                                            -           -                                       


    ECgene alternative splicing isoforms for PDZD4

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    PDZD4 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CGGCCTGGGG
    PDZD4 Expression
    About this image


    PDZD4 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Inner Cell Mass (Early Embryonic Tissues)    fully expand to see all 2 entries
             Human embryonic stem cells (family)
     
     Blood (Hematopoietic System)
             Natural Killer Cells Peripheral Blood
     
     Eye (Sensory Organs)
             Retina
     
     Brain (Nervous System)
             Cerebral Cortex
    PDZD4 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    PDZD4 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.92732

    UniProtKB/Swiss-Prot: PDZD4_HUMAN, Q76G19
    Tissue specificity: Brain-specific. Expressed in fetal and adult brain. Up-regulated in synovial carcinomas

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PDZD4

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for PDZD4 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Pdzd41 , 5 PDZ domain containing 41, 5 86.68(n)1
    93.34(a)1
      X (37.41 cM)5
    2454691  NM_001029868.11  NP_001025039.11 
     737933595 
    lizard
    (Anolis carolinensis)
    Reptilia PDZD46
    PDZ domain containing 4
    71(a)
    1 ↔ 1
    2(87870026-87885092)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia pdzd41 PDZ domain containing 4 68.76(n)
    73.76(a)
      100216079  NM_001142064.1  NP_001135536.1 
    zebrafish
    (Danio rerio)
    Actinopterygii pdzd41 PDZ domain containing 4 59.39(n)
    57.94(a)
      553320  XM_683940.6  XP_689032.4 
    fruit fly
    (Drosophila melanogaster)
    Insecta Slip16
    Slip1
    18(a)
    1 → many
    4(684214-690510)
    worm
    (Caenorhabditis elegans)
    Secernentea C50F7.66
    Protein C50F7.6 (C50F7.6) mRNA, complete cds
    22(a)
    1 → many
    IV(7720566-7723199) WBGene00016846


    ENSEMBL Gene Tree for PDZD4 (if available)
    TreeFam Gene Tree for PDZD4 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for PDZD4 gene
    PDZRN42  PDZRN32  
    3 SIMAP similar genes for PDZD4 using alignment to 5 protein entries:     PDZD4_HUMAN (see all proteins):
    PDZRN4    PDZRN3    DLG4

    Find genes that share paralogs with PDZD4           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for PDZD4 (see all 413)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0359524
    A breast cancer sample4--see VAR_0359522 R C mis40--------
    rs59453561,2
    C,H--141755046(+) GGACAT/CCCCAT 1 -- us2k1 tfbs312Minor allele frequency- C:0.00NS EA WA NA CSA 431
    rs1817112671,2
    --141755048(+) ACACCC/TCATCA 1 -- us2k10--------
    rs1428412101,2
    --141755067(+) CATGAA/GGCCAT 1 -- us2k10--------
    rs1461333201,2
    --141755069(+) TGAGGC/TCATAG 1 -- us2k10--------
    rs1401169871,2
    --141755214(+) CCCCAC/TGATCA 1 -- us2k10--------
    rs588837851,2
    C,F--153067146(+) ACTAGA/GTGCCT 1 -- ds50011Minor allele frequency- G:0.00WA 2
    rs120135551,2
    C,H--153067172(+) CCTTGC/ATAGGC 1 -- ds50013Minor allele frequency- A:0.10NA 10
    rs1143414471,2
    C--153067508(+) ACCGAA/GGGCTG 1 -- ds50010--------
    rs22693671,2
    C,F,O,A,H--153067740(+) GCAGCC/GTAGTT 1 -- ut31 ese34Minor allele frequency- G:0.13NS EA 418

    HapMap Linkage Disequilibrium report for PDZD4 (153067621 - 153096020 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for PDZD4:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv7159CNV Loss18451855
    esv33199CNV Gain+Loss17666407
    nsv469867CNV Complex16826518

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing PDZD4
    DNA2.0 Custom Variant and Variant Library Synthesis for PDZD4

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 300634    OMIM disorders: --


    Find genes that share disorders with PDZD4           About GenesLikeMe


    Export disorders for PDZD4 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for PDZD4 gene, integrated from 10 sources (see all 11):
    (articles sorted by number of sources associating them with PDZD4)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of PDZK4, a novel human gene with PDZ domains, that is upregulated in synovial sarcomas. (PubMed id 15077175)1, 2, 3 Nagayama S.... Nakamura Y. (Oncogene 2004)
    2. Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10819331)1, 2, 3 Nagase T.... Ohara O. (DNA Res. 2000)
    3. Identification and characterization of human PDZRN4L gene and mouse Pdzrn4l gene in silico. (PubMed id 15138636)1, 2, 9 Katoh M. and Katoh M. (Int. J. Mol. Med. 2004)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    6. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (Sci. Signal. 2011)
    7. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (J. Biol. Chem. 2011)
    8. The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)2 Sjoeblom T.... Velculescu V.E. (Science 2006)
    9. A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. (PubMed id 16713569)1 Lim J.... Zoghbi H.Y. (Cell 2006)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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      Query String
    PubMed
    OMIM
    NCBI Bookshelf
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 57595 HGNC: 21167 AceView: PDZK4 Ensembl:ENSG00000067840 euGenes: HUgn57595
    ECgene: PDZD4 H-InvDB: PDZD4

    (According to HUGE)
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    HUGE: KIAA1444

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for PDZD4 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for PDZD4 gene:
    Search GeneIP for patents involving PDZD4

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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