Aliases for PDXK Gene
External Ids for PDXK Gene
Previous HGNC Symbols for PDXK Gene
Previous GeneCards Identifiers for PDXK Gene
The protein encoded by this gene phosphorylates vitamin B6, a step required for the conversion of vitamin B6 to pyridoxal-5-phosphate, an important cofactor in intermediary metabolism. The encoded protein is cytoplasmic and probably acts as a homodimer. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
GeneCards Summary for PDXK Gene
PDXK (Pyridoxal (Pyridoxine, Vitamin B6) Kinase) is a Protein Coding gene. Among its related pathways are Metabolism and Metabolism of water-soluble vitamins and cofactors. GO annotations related to this gene include protein homodimerization activity and pyridoxal phosphate binding.
UniProtKB/Swiss-Prot for PDXK Gene
Required for synthesis of pyridoxal-5-phosphate from vitamin B6.