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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

PDLIM1 Gene

protein-coding   GIFtS: 56
GCID: GC10M096997

PDZ and LIM domain 1

(Previous name: PDZ and LIM domain 1 (elfin) )
(Previous symbol: CLIM1)
 Explore 27 diseases affiliated with
PDLIM1 via
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Biological research products
for PDLIM1    

Aliases
for PDLIM1 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
PDZ And LIM Domain 11 2     PDZ And LIM Domain 1 (Elfin)1
CLIM11 2 3 5     Carboxyl Terminal LIM Domain Protein 12
CLP361 2 3 5     Elfin3
CLP-361 2     PDZ And LIM Domain Protein 12
HCLIM11     Elfin3
LIM Domain Protein CLP-362 3     C-Terminal LIM Domain Protein 13

External Ids:    HGNC: 20671   Entrez Gene: 91242   Ensembl: ENSG000001074387   OMIM: 6059005   UniProtKB: O001513   

Export aliases for PDLIM1 gene to outside databases

Previous GC identifers: GC10M095890 GC10M096230 GC10M097128 GC10M096661 GC10M096987 GC10M090624


Summaries
for PDLIM1 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for PDLIM1:
This gene encodes a member of the enigma protein family. The protein contains two protein interacting domains, a PDZ
domain at the amino terminal end and one to three LIM domains at the carboxyl terminal. It is a cytoplasmic protein
associated with the cytoskeleton. The protein may function as an adapter to bring other LIM-interacting proteins to
the cytoskeleton. Pseudogenes associated with this gene are located on chromosomes 3, 14 and 17. (provided by RefSeq,
Oct 2012)

UniProtKB/Swiss-Prot: PDLI1_HUMAN, O00151
Function: Cytoskeletal protein that may act as an adapter that brings other proteins (like kinases) to the cytoskeleton

Gene Wiki entry for PDLIM1


Genomic Views
for PDLIM1 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000010.10  NC_018921.1  NT_030059.13  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the PDLIM1 gene promoter:
         STAT1   STAT4   STAT1beta   FOXD1   STAT5A   STAT1alpha   C/EBPalpha   Egr-2   STAT2   STAT3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: PDLIM1 promoter sequence
   Search SABiosciences Chromatin IP Primers for PDLIM1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PDLIM1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q23.1   Ensembl cytogenetic band:  10q24.1   HGNC cytogenetic band: 10q23.1

PDLIM1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PDLIM1 gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10M096997:  view genomic region     (about GC identifiers)

Start:
 96,997,329 bp from pter      End:
 97,050,781 bp from pter
Size:
 53,453 bases      Orientation:
 minus strand

Proteins
for PDLIM1 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: PDLI1_HUMAN, O00151 (See protein sequence)
Recommended Name: PDZ and LIM domain protein 1  
Size: 329 amino acids; 36072 Da
Subunit: Interacts with alpha-actinins 1, 2 and 4
Subcellular location: Cytoplasm (By similarity). Cytoplasm, cytoskeleton (By similarity). Note=Associates with the
actin stress fibers (By similarity)
2 PDB 3D structures from and Proteopedia for PDLIM1:
1X62 (3D)        2PKT (3D)    
Secondary accessions: B2RBS6 Q5VZH5 Q9BPZ9

Explore the universe of human proteins at neXtProt for PDLIM1: NX_O00151

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_O00151

    • PDLIM1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_066272.1  
    ENSEMBL proteins: 
     ENSP00000360305  

    Human Recombinant Protein Products: 
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    Novus Biologicals PDLIM1 Lysates
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    Browse ProSpec Recombinant Proteins
    Uscn Proteins for PDLIM1

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005667transcription factor complex IEA--
    GO:0005737cytoplasm IEA--
    GO:0005856cytoskeleton IEA--


    PDLIM1 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for PDLIM1

    Protein Domains /
    Families
    for PDLIM1 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    PDLIM1 for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR006643 ZASP
     IPR001478 PDZ
     IPR001781 Znf_LIM

    Graphical View of Domain Structure for InterPro Entry O00151

    ProtoNet protein and cluster: O00151

    3 Blocks protein families:
    IPB001478 PDZ/DHR/GLGF domain
    IPB001781 Zn-binding protein
    IPB006643 ZASP


    UniProtKB/Swiss-Prot: PDLI1_HUMAN, O00151
    Similarity: Contains 1 LIM zinc-binding domain
    Similarity: Contains 1 PDZ (DHR) domain


    Function
    for PDLIM1 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: PDLI1_HUMAN, O00151
    Function: Cytoskeletal protein that may act as an adapter that brings other proteins (like kinases) to the cytoskeleton

    miRNA
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    Inhib. RNA
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    OriGene shRNA RFP: PDLIM1
    OriGene siRNA: PDLIM1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat PDLIM1

    Gene Editing
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    Clone
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PDLIM1 

    Cell Line
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    Search LifeMap BioReagents cell lines for PDLIM1

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PDLIM1

    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003713transcription coactivator activity IEA--
    GO:0005515protein binding ----
    GO:0008270zinc ion binding IEA--


    PDLIM1 for ontologies           About GeneDecksing


    2 GenomeRNAi human phenotypes for PDLIM1:
     Downregulation of NF-kappaB pa  Downregulation of NF-kappaB pa 


    Pathways & Interactions
    for PDLIM1 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for PDLIM1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 14)

    5/21 Interacting proteins for PDLIM1 (O001512, 3 ENSP000003603054) via UniProtKB, MINT, STRING, and/or I2D (see all 21)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ACTN4O437072, 3, ENSP000002526994MINT-68435 I2D: score=7 STRING: ENSP00000252699
    MAPK6Q166592, 3MINT-8261604 I2D: score=2 
    RPS6KA5O755822, 3MINT-8269648 I2D: score=2 
    VIMP086702, 3, ENSP000002242374MINT-67503 I2D: score=5 STRING: ENSP00000224237
    SUPT4H1P632722, 3, ENSP000002255044MINT-8272399 I2D: score=2 STRING: ENSP00000225504
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001666response to hypoxia IEA--
    GO:0006355regulation of transcription, DNA-dependent IEA--
    GO:0006979response to oxidative stress TAS8522188


    PDLIM1 for ontologies           About GeneDecksing



    Drugs & Compounds
    for PDLIM1 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    PDLIM1 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for PDLIM1
    1 Novoseek chemical compound relationship for PDLIM1 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    calcium 5.81 2 2329796 (1), 12599114 (1)

    Search CenterWatch for drugs/clinical trials and news about PDLIM1 / PDLI1 

    Transcripts
    for PDLIM1 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for PDLIM1 gene: 
    NM_020992.3  

    Unigene Cluster for PDLIM1:

    PDZ and LIM domain 1
    Hs.368525  [show with all ESTs]
    Unigene Representative Sequence: AK091847
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000329399(uc001kkh.3) ENST00000492511 ENST00000477757 ENST00000490391
    ENST00000493949

    miRNA
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    Inhib. RNA
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    OriGene shRNA RFP: PDLIM1
    OriGene siRNA: PDLIM1
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    Clone
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    Primer
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PDLIM1

    Additional cDNA sequence: 

    AJ310549.1 AK091847.1 AK314792.1 BC000915.2 BC018755.1 U90878.1 

    20 DOTS entries:

    DT.448694  DT.100030819  DT.100887789  DT.100887791  DT.100030821  DT.121217697  DT.100887795  DT.100887785 
    DT.100887806  DT.121217657  DT.100035146  DT.100689814  DT.100801669  DT.100887804  DT.101955574  DT.120776564 
    DT.87016421  DT.95236934  DT.95373757  DT.87016420 

    24/667 AceView cDNA sequences (see all 667):

    BU156096 CR597094 AA460799 BM717497 CR610518 CR612014 BI517315 CR620933 
    BP374807 AI784259 CR593176 BX384453 BQ879641 CR614157 BX378611 T30467 
    CA392890 AW250842 CR603481 T35113 BG569627 AA303236 CD245363 BX338226 

    GeneLoc Exon Structure

    5/8 Alternative Splicing Database (ASD) splice patterns (SP) for PDLIM1 (see all 8)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b · 6c · 6d ^ 7a · 7b ^ 8 ^ 9a · 9b · 9c · 9d
    SP1:                    -     -                       -                                                               
    SP2:                    -     -     -     -           -                                                               
    SP3:                                                  -           -     -                                             
    SP4:                          -                       -                                                               
    SP5:                    -     -                       -     -     -     -     -     -                                 


    ECgene alternative splicing isoforms for PDLIM1

    Expression
    for PDLIM1 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    PDLIM1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CCCGGGAGCG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    PDLIM1 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    PureStem™ progenitor Z1 (Embryonic Progenitor Cell)
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See PDLIM1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for PDLIM1

    SOURCE GeneReport for Unigene cluster: Hs.368525

    UniProtKB/Swiss-Prot: PDLI1_HUMAN, O00151
    Tissue specificity: Strongly expressed in the heart and skeletal muscle, moderately expressed in the spleen, small
    intestine, colon, placenta, and lung. A lower level expression is seen in liver, thymus, kidney, prostate and pancreas
    and is not found in the brain, testis, ovary, and peripheral blood leukocytes

        SABiosciences Expression via Pathway-Focused PCR Array including PDLIM1: 
              Oxidative Stress in human mouse rat

    Primer
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    In Situ
    Assay Products:     
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    Orthologs
    for PDLIM1 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for PDLIM1 gene from 5/18 species (see all 18)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves PDLIM16
    		 Uncharacterized protein
    		 79(a)
    		 1 ↔ 1
    		 6(17527786-17564547)
    lizard
    (Anolis carolinensis)    		 Reptilia PDLIM16
    		 --
    		 73(a)
    		 1 ↔ 1
    		 GL343297.1(1553867-1582710)
    African clawed frog
    (Xenopus laevis)    		 Amphibia BC041514.12   -- 77.93(n)    BC041514.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii Dr.233762 Transcribed sequence with weak similarity to protein more 74.65(n)    CK027259.1 
    honey bee
    (Apis mellifera)    		 Insecta --
    --
    		 --
    		 27(a)
    25(a)
    		 many ↔ many
    many ↔ many
    		 Group16.4(117929-160922)
    GroupUn.6806(1178-2814)


    ENSEMBL Gene Tree for PDLIM1 (if available)
    TreeFam Gene Tree for PDLIM1 (if available) 

    Paralogs
    for PDLIM1 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for PDLIM1 gene
    PDLIM42  PDLIM32  PDLIM22  
    3 SIMAP similar genes for PDLIM1 using alignment to 1 protein entry:     PDLI1_HUMAN:
    PDLIM4    PDLIM3    PDLIM2

    PDLIM1 for paralogs           About GeneDecksing


    4 Pseudogenes.org Pseudogenes for PDLIM1
    PGOHUM00000248164 PGOHUM00000236979 PGOHUM00000236993 PGOHUM00000238114


    Genomic Variants
    for PDLIM1 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/977 NCBI SNPs in PDLIM1 are shown (see all 977)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 10 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs455746361,2
    		C,F,--96996877(-) ACCTCG/ATGATC 1 -- ds50015Minor allele frequency- A:0.01NS 188
    rs455386321,2
    		C,--96996892(-) GGTCTT/CGATCT 1 -- ds50015Minor allele frequency- C:0.01NS 188
    rs456104331,2
    		F--96996900(-) GCCAGC/GATGGT 1 -- ds50015Minor allele frequency- G:0.01NS 188
    rs454830971,2
    		C,F,--96996911(-) TCACCA/GCATTA 1 -- ds50016Minor allele frequency- G:0.05NS NA 190
    rs454658951,2
    		C,F,--96996920(-) GACGGG/AGTTTC 1 -- ds50016Minor allele frequency- A:0.01NS CSA 190
    rs455955351,2
    		C,F,--96996922(-) GAGACG/AGGGTT 1 -- ds50015Minor allele frequency- A:0.02NS 188
    rs127639391,2
    		C,F,--96996940(+) aatacA/Gaaaaa 1 -- ds50019Minor allele frequency- G:0.06NS NA 196
    rs1451385101,2
    		--96996968(+) GCAGGC/TGCCTG 1 -- ds50010--------
    rs1841109341,2
    		--96997021(+) AACCCA/GGGAGG 1 -- ds50010--------
    rs1869243351,2
    		--96997079(+) CGACAC/TAGCGA 1 -- ds50010--------

    HapMap Linkage Disequilibrium report for PDLIM1 (96997329 - 97050781 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for PDLIM1
         1 CNV: 65767

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PDLIM1
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    Disorders / Diseases
    for PDLIM1 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    PDLIM1 for disorders           About GeneDecksing

    OMIM gene information: 605900    OMIM disorders: --

    20/27 diseases for PDLIM1 (see all 27):    About MalaCards
    mitral valve prolapse    johanson-blizzard syndrome    dental enamel hypoplasia    supravalvular aortic stenosis
    williams-beuren syndrome    acanthosis nigricans    aortic valve stenosis    pulmonary valve stenosis
    hyperacusis    otitis media    faces syndrome    scimitar syndrome
    donohue syndrome    strabismus    williams syndrome    chronic granulomatous disease
    intellectual disability    hypercalcemia    hypertrichosis    glomerulopathy

    5 diseases from the University of Copenhagen DISEASES database for PDLIM1:
    Aortic valve stenosis     Williams-Beuren syndrome     Donohue Syndrome     Intellectual disability
    Hypercalcemia

    10 Novoseek disease relationships for PDLIM1 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    aortic stenosis supravalvular 93.4 11 1824530 (1), 7503839 (1), 9285033 (1), 8766044 (1) (see all 10)
    williams syndrome 93.3 19 8138341 (3), 13677282 (2), 2033166 (2), 14635404 (1) (see all 15)
    hypercalcemia 68.7 9 15303821 (1), 9285033 (1), 13677282 (1), 2033166 (1) (see all 9)
    mental retardation 65.9 12 13677282 (2), 1824530 (1), 7503839 (1), 8527335 (1) (see all 11)
    developmental delay 55.1 2 14636357 (1), 2329796 (1)
    heart defects congenital 42.3 3 17625998 (1), 14636357 (1), 12599114 (1)
    mitral valve prolapse 41.3 1 8351994 (1)
    aortic stenosis 40.8 3 1488232 (1), 8469630 (1), 8620979 (1)
    mitral regurgitation 35.7 2 8351994 (1), 2038171 (1)
    strabismus 31.6 1 7503839 (1)

    Human Genome Epidemiology (HuGE) Navigator: PDLIM1 (4 documents)

    Export disorders for PDLIM1 gene to outside databases

    Publications
    for PDLIM1 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for PDLIM1 gene, integrated from 9 sources (see all 78):
    (articles sorted by number of sources associating them with PDLIM1)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Interaction of hCLIM1, an enigma family protein, with alpha-actinin 2. (PubMed id 10861853)1, 2, 3, 9 Kotaka M....Waye M.M. (2000)
    2. Human CLP-36, a PDZ-domain and LIM-domain protein, binds to alpha- actinin-1 and associates with actin filaments and stress fibers in activated platelets and endotheleial cells. (PubMed id 11110697)1, 2, 9 Bauer K.... Siess W. (2000)
    3. CLP-36 PDZ-LIM protein associates with nonmuscle alpha-actinin-1 and alpha-actinin-4. (PubMed id 10753915)1, 2, 9 Vallenius T.... Makela T.P. (2000)
    4. Characterization of the human 36-kDa carboxyl terminal LIM domain protein (hCLIM1). (PubMed id 10022510)1, 2, 9 Kotaka M.... Waye M.M.Y. (1999)
    5. Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. (PubMed id 15592455)1, 2 Rush J.... Comb M.J. (2005)
    6. The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)1, 2 Deloukas P.... Rogers J. (2004)
    7. Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry. (PubMed id 15144186)1, 2 Brill L.M....Peters E.C. (2004)
    8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    9. Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. (PubMed id 12665801)1, 2 Gevaert K.... Vandekerckhove J. (2003)
    10. Expression of the actin stress fiber-associated protein CLP36 in the human placenta. (PubMed id 16609848)1, 9 Miehe U....Huppertz B. (2006)

    External Searches for PDLIM1 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    Aliases
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    Genome Databases showing PDLIM1 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 9124 HGNC: 2067 AceView: PDLIM1 Ensembl:ENSG00000107438 euGenes: HUgn9124
    ECgene: PDLIM1 H-InvDB: PDLIM1

    Other Databases showing PDLIM1 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing PDLIM1 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for PDLIM1 Pharmacogenomics, SNPs, Pathways
    NIEHS-SNPshttp://egp.gs.washington.edu/data/pdlim1/

    Intellectual Property
    for PDLIM1 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for PDLIM1 gene:
    Search GeneIP for patents involving PDLIM1

    GeneCards and IP:
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