Aliases for PDIA4 Gene
External Ids for PDIA4 Gene
Previous GeneCards Identifiers for PDIA4 Gene
This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, three catalytically active thioredoxin (TRX) domains, two TRX-like domains and a C-terminal ER-retention sequence. This protein, when bound to cyclophilin B, enhances the rate of immunoglobulin G intermolecular disulfide bonding and antibody assembly. [provided by RefSeq, Dec 2016]
GeneCards Summary for PDIA4 Gene
PDIA4 (Protein Disulfide Isomerase Family A Member 4) is a Protein Coding gene. Among its related pathways are Protein processing in endoplasmic reticulum and Translational Control. GO annotations related to this gene include poly(A) RNA binding and isomerase activity. An important paralog of this gene is PDIA3.