Aliases for PDGFRL Gene
External Ids for PDGFRL Gene
Previous GeneCards Identifiers for PDGFRL Gene
This gene encodes a protein with significant sequence similarity to the ligand binding domain of platelet-derived growth factor receptor beta. Mutations in this gene, or deletion of a chromosomal segment containing this gene, are associated with sporadic hepatocellular carcinomas, colorectal cancers, and non-small cell lung cancers. This suggests this gene product may function as a tumor suppressor. [provided by RefSeq, Jul 2008]
GeneCards Summary for PDGFRL Gene
PDGFRL (Platelet-Derived Growth Factor Receptor-Like) is a Protein Coding gene. Diseases associated with PDGFRL include hepatocellular carcinoma and colorectal cancer. GO annotations related to this gene include platelet activating factor receptor activity and platelet-derived growth factor beta-receptor activity.