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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

PDGFRL Gene

protein-coding   GIFtS: 51
GCID: GC08P017436

platelet-derived growth factor receptor-like
 Explore 21 diseases affiliated with
PDGFRL via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for PDGFRL    

Aliases
for PDGFRL gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Platelet-Derived Growth Factor Receptor-Like1 2     PDGRL2 5
PRLTS1 2 3 5     Platelet-Derived Growth Factor Receptor-Like Protein2
PDGF Receptor Beta-Like Tumor Suppressor2 3     Platelet-Derived Growth Factor-Beta-Like Tumor Suppressor2
PDGFR-Like Protein2 3     

External Ids:    HGNC: 88051   Entrez Gene: 51572   Ensembl: ENSG000001042137   OMIM: 6045845   UniProtKB: Q151983   

Export aliases for PDGFRL gene to outside databases

Previous GC identifers: GC08P017327 GC08P017514 GC08P017444 GC08P017478 GC08P017435 GC08P015978


Summaries
for PDGFRL gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for PDGFRL:
This gene encodes a protein with significant sequence similarity to the ligand binding domain of platelet-derived
growth factor receptor beta. Mutations in this gene, or deletion of a chromosomal segment containing this gene, are
associated with sporadic hepatocellular carcinomas, colorectal cancers, and non-small cell lung cancers. This suggests
this gene product may function as a tumor suppressor. (provided by RefSeq, Jul 2008)




Genomic Views
for PDGFRL gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000008.10  NC_018919.1  NT_167187.1  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the PDGFRL gene promoter:
         HFH-3   TBP   Pbx1a   Tal-1   Pax-2   FOXD3   CUTL1   E4BP4   E47   FOXI1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: PDGFRL promoter sequence
   Search SABiosciences Chromatin IP Primers for PDGFRL

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PDGFRL


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8p22-p21.3   Ensembl cytogenetic band:  8p22   HGNC cytogenetic band: 8p22-p21.3

PDGFRL Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PDGFRL gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08P017436:  view genomic region     (about GC identifiers)

Start:
 17,433,942 bp from pter      End:
 17,501,580 bp from pter
Size:
 67,639 bases      Orientation:
 plus strand

Proteins
for PDGFRL gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: PGFRL_HUMAN, Q15198 (See protein sequence)
Recommended Name: Platelet-derived growth factor receptor-like protein precursor  
Size: 375 amino acids; 41861 Da
Subunit: Forms a complex composed of PDGFRL, TNK2 and GRB2
Subcellular location: Secreted (Probable)
Secondary accessions: A8K085 Q6FH04

Explore the universe of human proteins at neXtProt for PDGFRL: NX_Q15198

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q15198

    • PDGFRL Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_006198.1  
    ENSEMBL proteins: 
     ENSP00000251630   ENSP00000444211   ENSP00000381149  

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    Novus Biologicals PDGFRL Protein
    Novus Biologicals PDGFRL Lysate
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for PDGFRL

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575cellular_component ND--
    GO:0005576extracellular region IEA--


    PDGFRL for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for PDGFRL

    Protein Domains /
    Families
    for PDGFRL gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    PDGFRL for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR013098 Ig_I-set
     IPR013783 Ig-like_fold
     IPR007110 Ig-like_dom
     IPR003599 Ig_sub

    Graphical View of Domain Structure for InterPro Entry Q15198

    ProtoNet protein and cluster: Q15198

    1 Blocks protein family: IPB003599 Immunoglobulin subtype

    UniProtKB/Swiss-Prot: PGFRL_HUMAN, Q15198
    Similarity: Contains 2 Ig-like C2-type (immunoglobulin-like) domains


    Function
    for PDGFRL gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:
         Genatlas biochemistry entry for PDGFRL:
    platelet-derived growth factor receptor-like

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat PDGFRL
    3 QIAGEN miScript miRNA Assays for microRNAs that regulate PDGFRL:
    hsa-miR-3163 hsa-miR-633 hsa-miR-617
    SwitchGear 3'UTR luciferase reporter plasmid: PDGFRL 3' UTR sequence
    Inhib. RNA
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    OriGene shRNA RFP: PDGFRL
    OriGene siRNA: PDGFRL
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat PDGFRL

    Gene Editing
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    Clone
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    Cell Line
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    Search LifeMap BioReagents cell lines for PDGFRL

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PDGFRL

    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004992platelet activating factor receptor activity TAS7898930
    GO:0005019platelet-derived growth factor beta-receptor activity TAS7898930


    PDGFRL for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for PDGFRL:
     Decreased influenza A/WSN/33 r 


    Pathways & Interactions
    for PDGFRL gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for PDGFRL

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    3 Interacting proteins for PDGFRL (ENSP000002516304) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    BOCENSP000003475464STRING: ENSP00000347546
    DCNENSP000000527544STRING: ENSP00000052754
    ASPNENSP000003646944STRING: ENSP00000364694
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008150biological_process ND--
    GO:0035791platelet-derived growth factor receptor-beta signaling pathway TAS7898930


    PDGFRL for ontologies           About GeneDecksing



    Drugs & Compounds
    for PDGFRL gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    PDGFRL for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for PDGFRL
    1 Novoseek chemical compound relationship for PDGFRL gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    tyrosine 9.5 2 1717981 (1), 9476070 (1)

    Search CenterWatch for drugs/clinical trials and news about PDGFRL / PGFRL 

    Transcripts
    for PDGFRL gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for PDGFRL gene: 
    NM_006207.2  

    Unigene Cluster for PDGFRL:

    Platelet-derived growth factor receptor-like
    Hs.458573  [show with all ESTs]
    Unigene Representative Sequence: NM_006207
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000251630 ENST00000523248 ENST00000541323(uc003wxr.3) ENST00000398074


    miRNA
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    3 QIAGEN miScript miRNA Assays for microRNAs that regulate PDGFRL:
    hsa-miR-3163 hsa-miR-633 hsa-miR-617
    SwitchGear 3'UTR luciferase reporter plasmid: PDGFRL 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for PDGFRL (see all 7)
    OriGene shRNA RFP: PDGFRL
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    Clone
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    Primer
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    Additional cDNA sequence: 

    AK289450.1 BC010927.1 CR541952.1 D37965.1 

    4 DOTS entries:

    DT.100700736  DT.440990  DT.121480841  DT.451623 

    24/106 AceView cDNA sequences (see all 106):

    BM671983 BU624775 AA347805 CB268406 AI264744 AA461197 BX281242 D62559 
    BQ010346 CR605626 BQ575319 BM720230 BI754977 CR596869 BQ014860 R53211 
    BU860628 BQ880742 NM_006207 BV177726 CR541952 BI830160 BQ130055 AA232627 

    GeneLoc Exon Structure


    Expression
    for PDGFRL gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    PDGFRL expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TGTAAACAAT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    PDGFRL expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    2 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    BoneThoracic RibBone
    CartilageMeckel's CartilageCartilage
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 5 LifeMap Cells 
    NameCategory
    PureStem™ mesenchymal Progenitor SK11 (Embryonic Progenitor Cell)Adipose, Bone, Cartilage
    PureStem™ mesenchymal progenitor 7SMOO32 (Embryonic Progenitor Cell)Adipose, Bone, Cartilage
    PureStem™ mesenchymal progenitor 7PEND24 (Embryonic Progenitor Cell)Cartilage, Neural Crest
    PureStem™ progenitor EN27 (Embryonic Progenitor Cell)
    PureStem™ progenitor W10 (Embryonic Progenitor Cell)

    See PDGFRL Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for PDGFRL

    SOURCE GeneReport for Unigene cluster: Hs.458573

    UniProtKB/Swiss-Prot: PGFRL_HUMAN, Q15198
    Tissue specificity: Expressed in colon, lung and liver

        SABiosciences Expression via Pathway-Focused PCR Array including PDGFRL: 
              G Protein Coupled Receptors 384HT in human mouse rat

    Primer
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    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PDGFRL

    Orthologs
    for PDGFRL gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of chordates.

    Orthologs for PDGFRL gene from 5/12 species (see all 12)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Pdgfrl1 , 5 platelet-derived growth factor receptor-like1, 5 84.09(n)1
    89.33(a)1    		   8 (23.89 cM)5
    687971  NM_026840.31  NP_081116.31 
     409262125 
    chicken
    (Gallus gallus)    		 Aves PDGFRL1 platelet-derived growth factor receptor-like 69.61(n)
    68.45(a)    		   769077  XM_001231867.2  XP_001231868.2 
    lizard
    (Anolis carolinensis)    		 Reptilia PDGFRL6
    		 --
    		 72(a)
    		 1 ↔ 1
    		 5(108948918-108977377)
    African clawed frog
    (Xenopus laevis)    		 Amphibia Xl.237032 Xenopus laevis transcribed sequence with moderate similarity more 77.66(n)    CB562090.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii zgc561042 similar to platelet-derived growth factor receptor-like 73.72(n)   393284  BC062835.1 


    ENSEMBL Gene Tree for PDGFRL (if available)
    TreeFam Gene Tree for PDGFRL (if available) 

    Paralogs
    for PDGFRL gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    		  --

    Genomic Variants
    for PDGFRL gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/2324 NCBI SNPs in PDGFRL are shown (see all 2324)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 8 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs347065841,2
    		C,F,--17431971(+) GAAAAG/TTGGGT 1 -- us2k17Minor allele frequency- T:0.13NA CSA WA EA 365
    rs1492778911,2
    		--17431982(+) GTTACA/GGGTAA 1 -- us2k10--------
    rs357843471,2
    		C--17432083(+) AAAAA-/ATCAGG 1 -- us2k10--------
    rs27050541,2
    		C,F,A,--17432104(-) TTTCCG/CAAGGC 1 -- us2k16Minor allele frequency- C:0.24WA NA EA 364
    rs767902961,2
    		F,--17432141(+) GAGCTG/TCAAGA 1 -- us2k11Minor allele frequency- T:0.02NA 120
    rs25881691,2
    		C,F,A,--17432152(-) AATAAG/ACATTA 1 -- us2k16Minor allele frequency- A:0.26WA NA EA 364
    rs27050531,2
    		C,A,--17432189(-) TCCTTT/CTCCAA 1 -- us2k1 trp35Minor allele frequency- C:0.25WA NA EA 362
    rs1445107461,2
    		--17432212(+) AACACG/TACATT 1 -- us2k10--------
    rs735624481,2
    		C,--17432268(+) TTTTAT/CAGTGA 1 -- us2k12Minor allele frequency- C:0.06WA 120
    rs1485560891,2
    		--17432361(+) ATAAGC/TCTTGT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for PDGFRL (17433942 - 17501580 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 7 variations for PDGFRL
         7 CNVs: 95294 33020 52459 2743 3724 10248 9089

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    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PDGFRL
    DNA2.0 Custom Variant and Variant Library Synthesis for PDGFRL

    Disorders / Diseases
    for PDGFRL gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    PDGFRL for disorders           About GeneDecksing

    OMIM gene information: 604584   
    OMIM disorders: 114550  114500  
    UniProtKB/Swiss-Prot: PGFRL_HUMAN, Q15198
  • Defects in PDGFRL are associated with colorectal cancer (CRC) [MIM:114500]
  • Note=A polymorphism in PDGFRL has been reported to be associated with susceptibility to Behcet disease
    • (PubMed:19815557). Behcet disease is a complex multiple-system disorder characterized by recurrent oral ulcerations,
    recurrent genital ulcerations, typical skin lesions, and uveitis. Behcet disease also involves joints, blood vessels,
    musculoskeletal, neurological systems, and the gastrointestinal tract

    20/21 diseases for PDGFRL (see all 21):    About MalaCards
    hepatocellular carcinoma    colorectal cancer    lung cancer    carcinoma
    non-small cell lung carcinoma    basal cell carcinoma    squamous cell carcinoma    endometrial adenocarcinoma
    lung carcinoma    hepatitis b    prostate cancer    ovarian carcinoma
    esophageal cancer    esophagitis    ovarian cancer    hepatocellular cancer
    melanoma    adenocarcinoma    prostatitis    hepatitis

    4 Novoseek disease relationships for PDGFRL gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    tumors 20.6 4 9197531 (2), 7898930 (1), 10362129 (1)
    prostate cancer 17.8 3 9197531 (3)
    cancer 12.3 1 19882270 (1)
    metastasis 0.842 1 19343157 (1)

    Human Genome Epidemiology (HuGE) Navigator: PDGFRL (1 document)

    Export disorders for PDGFRL gene to outside databases

    Publications
    for PDGFRL gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for PDGFRL gene, integrated from 9 sources (see all 35):
    (articles sorted by number of sources associating them with PDGFRL)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Isolation of a candidate tumor suppressor gene on chromosome 8p21.3- p22 that is homologous to an extracellular domain of the PDGF receptor beta gene. (PubMed id 7898930)1, 2, 9 Fujiwara Y....Nakamura Y. (1995)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Expression and functional characterization of platele t-derived growth factor receptor-like gene. (PubMed id 20333786)1, 9 Guo F.J....Li G.C. (2010)
    4. Genetic variant on PDGFRL associated with Behcet disease in Chinese Han populations. (PubMed id 22926996)2 Hou S.... Yang P. (2013)
    5. New genetic associations detected in a host response study to hepatitis B vaccine. (PubMed id 20237496)1 Davila S....Seielstad M. (2010)
    6. Cytoplasmic ACK1 interaction with multiple receptor t yrosine kinases is mediated by Grb2: an analysis of ACK1 effects on Axl signali ng. (PubMed id 19815557)2 Pao-Chun L....Manser E. (2009)
    7. An integrative approach to characterize disease-speci fic pathways and their coordination: a case study in cancer. (PubMed id 18366601)1 Xu M....Zhou X.J. (2008)
    8. The gene expression profiles of primary and metastatic melanoma yields a transition point of tumor progression and metastasis. (PubMed id 18442402)1 Riker A.I....Matta J. (2008)
    9. Genetic background of different cancer cell lines influences the gene set involved in chromosome 8 mediated breast tumor suppression. (PubMed id 16552773)1 Seitz S....Scherneck S. (2006)
    10. Five genes from chromosomal band 8p22 are significantly down- regulated in ovarian carcinoma: N33 and EFA6R have a potential impact on overall survival. (PubMed id 16270321)1 Pils D.... Krainer M. (2005)

    External Searches for PDGFRL gene

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    Genome Databases showing PDGFRL gene

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    Entrez Gene: 5157 HGNC: 8805 AceView: PDGFRL Ensembl:ENSG00000104213 euGenes: HUgn5157
    ECgene: PDGFRL H-InvDB: PDGFRL

    Other Databases showing PDGFRL gene

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    Specialized Databases showing PDGFRL gene

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    PharmGKB entry for PDGFRL Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for PDGFRL Genetics and Cytogenetics in Oncology and Haematology

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