Aliases for PDE4DIP Gene
External Ids for PDE4DIP Gene
Previous HGNC Symbols for PDE4DIP Gene
Previous GeneCards Identifiers for PDE4DIP Gene
The protein encoded by this gene serves to anchor phosphodiesterase 4D to the Golgi/centrosome region of the cell. Defects in this gene may be a cause of myeloproliferative disorder (MBD) associated with eosinophilia. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2010]
GeneCards Summary for PDE4DIP Gene
PDE4DIP (Phosphodiesterase 4D Interacting Protein) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include binding and enzyme binding. An important paralog of this gene is CDK5RAP2.
UniProtKB/Swiss-Prot for PDE4DIP Gene
Functions as an anchor sequestering components of the cAMP-dependent pathway to Golgi and/or centrosomes (By similarity). Forms a complex with AKAP9: the complex recruits CAMSAP2 to the Golgi apparatus, leading to tether non-centrosomal minus-end microtubules to the Golgi, an important step for polarized cell movement (PubMed:27666745, PubMed:28814570).