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Aliases for PDE4DIP Gene

Aliases for PDE4DIP Gene

  • Phosphodiesterase 4D Interacting Protein 2 3 5
  • Cardiomyopathy-Associated Protein 2 3 4
  • Myomegalin 2 3
  • CMYA2 3 4
  • MMGL 3 4
  • Myomegalin/Phosphodiesterase 4D Interacting Protein Variant 8 3
  • Phosphodiesterase 4D-Interacting Protein 4
  • Cardiomyopathy Associated 2 2
  • KIAA0454 4
  • KIAA0477 4

External Ids for PDE4DIP Gene

Previous HGNC Symbols for PDE4DIP Gene

  • CMYA2

Previous GeneCards Identifiers for PDE4DIP Gene

  • GC01P144477
  • GC01M141455
  • GC01M142582
  • GC01M142604
  • GC01M142606
  • GC01M142189
  • GC01M143563
  • GC01M144833
  • GC01M119142
  • GC01M144836

Summaries for PDE4DIP Gene

Entrez Gene Summary for PDE4DIP Gene

  • The protein encoded by this gene serves to anchor phosphodiesterase 4D to the Golgi/centrosome region of the cell. Defects in this gene may be a cause of myeloproliferative disorder (MBD) associated with eosinophilia. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2010]

GeneCards Summary for PDE4DIP Gene

PDE4DIP (Phosphodiesterase 4D Interacting Protein) is a Protein Coding gene. Diseases associated with PDE4DIP include Eosinophilia and Peritoneum Cancer. GO annotations related to this gene include binding and enzyme binding. An important paralog of this gene is CDK5RAP2.

UniProtKB/Swiss-Prot for PDE4DIP Gene

  • May function as an anchor sequestering components of the cAMP-dependent pathway to Golgi and/or centrosomes.

Gene Wiki entry for PDE4DIP Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PDE4DIP Gene

Genomics for PDE4DIP Gene

Regulatory Elements for PDE4DIP Gene

Enhancers for PDE4DIP Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01F148793 1.6 FANTOM5 Ensembl ENCODE 29.7 -14.2 -14210 1.3 ATF1 PKNOX1 ZNF493 GLI4 ZNF416 YY2 CREB3 MEF2D ZNF585B PBX2 PDE4DIP ENSG00000227700 LOC101927468 ENSG00000271546 LOC100996517
GH01F148950 1.8 FANTOM5 Ensembl ENCODE 20.5 +148.7 148733 13.5 HDGF PKNOX1 MLX ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 SLC30A9 LOC647481 SF3B4 PDE4DIP LOC101927468 ENSG00000227700 HIST2H2AB ENSG00000261716 SV2A PIR33316 ENSG00000254913
GH01F148840 1.5 FANTOM5 Ensembl ENCODE 22.5 +33.3 33291 1.4 ATF1 PTRF ZEB1 ZNF366 CBX5 FOS KLF13 ZNF280D CEBPB ZNF264 LOC647481 PDE4DIP RN7SKP88 GC01M148879
GH01F148771 1.6 FANTOM5 Ensembl ENCODE 16.6 -34.2 -34217 4.7 PKNOX1 TBL1XR1 ZNF493 ZFP64 RAD21 YY1 GTF3C2 CEBPB NR2F2 POLR2H LOC647481 PDE4DIP LOC100996517 GC01P148750
GH01F148973 1.4 FANTOM5 Ensembl ENCODE 16.1 +167.6 167586 3.6 PKNOX1 TBL1XR1 JUN ASH2L RBBP5 BMI1 ZBTB40 RELA CREM MTA2 PDE4DIP NBPF9 LOC653513 PIR33316 ENSG00000254913
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around PDE4DIP on UCSC Golden Path with GeneCards custom track

Promoters for PDE4DIP Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001749886 633 800 CBX3 SREBF2 SIN3A DMAP1 ZNF48 RAD21 GATA2 ZNF263 MCM3 REST

Genomic Location for PDE4DIP Gene

Chromosome:
1
Start:
148,808,167 bp from pter
End:
149,048,286 bp from pter
Size:
240,120 bases
Orientation:
Plus strand

Genomic View for PDE4DIP Gene

Genes around PDE4DIP on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
PDE4DIP Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PDE4DIP Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PDE4DIP Gene

Proteins for PDE4DIP Gene

  • Protein details for PDE4DIP Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5VU43-MYOME_HUMAN
    Recommended name:
    Myomegalin
    Protein Accession:
    Q5VU43
    Secondary Accessions:
    • A2RU15
    • O75042
    • O75065
    • Q2YDC1
    • Q5VU42
    • Q5VU44
    • Q5VU45
    • Q5VU46
    • Q5VU47
    • Q5VU48
    • Q5VU49
    • Q68DU2
    • Q6AZ93
    • Q6PK88
    • Q86T40
    • Q86TB2
    • Q8N3W0
    • Q8TAY9
    • Q9HCP2
    • Q9HCP3
    • Q9HCP4
    • Q9HCP5

    Protein attributes for PDE4DIP Gene

    Size:
    2346 amino acids
    Molecular mass:
    265080 Da
    Quaternary structure:
    • Interacts with PDE4D.
    SequenceCaution:
    • Sequence=AAH04860.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence.; Evidence={ECO:0000305}; Sequence=BAA32299.2; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305}; Sequence=BAA32322.2; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305}; Sequence=CAD91152.1; Type=Frameshift; Positions=1507; Evidence={ECO:0000305}; Sequence=CAH18128.1; Type=Miscellaneous discrepancy; Note=Probable cloning artifact.; Evidence={ECO:0000305};

    Alternative splice isoforms for PDE4DIP Gene

neXtProt entry for PDE4DIP Gene

Post-translational modifications for PDE4DIP Gene

No data available for DME Specific Peptides for PDE4DIP Gene

Domains & Families for PDE4DIP Gene

Protein Domains for PDE4DIP Gene

Suggested Antigen Peptide Sequences for PDE4DIP Gene

Graphical View of Domain Structure for InterPro Entry

Q5VU43

UniProtKB/Swiss-Prot:

MYOME_HUMAN :
  • Contains 1 NBPF domain.
Domain:
  • Contains 1 NBPF domain.
genes like me logo Genes that share domains with PDE4DIP: view

No data available for Gene Families for PDE4DIP Gene

Function for PDE4DIP Gene

Molecular function for PDE4DIP Gene

UniProtKB/Swiss-Prot Function:
May function as an anchor sequestering components of the cAMP-dependent pathway to Golgi and/or centrosomes.

Gene Ontology (GO) - Molecular Function for PDE4DIP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 17923693
GO:0019899 enzyme binding ISS 11134006
genes like me logo Genes that share ontologies with PDE4DIP: view
genes like me logo Genes that share phenotypes with PDE4DIP: view

Animal Models for PDE4DIP Gene

MGI Knock Outs for PDE4DIP:

Animal Model Products

Clone Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for PDE4DIP Gene

Localization for PDE4DIP Gene

Subcellular locations from UniProtKB/Swiss-Prot for PDE4DIP Gene

Golgi apparatus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm. Nucleus.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for PDE4DIP gene
Compartment Confidence
cytoskeleton 5
nucleus 5
golgi apparatus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for PDE4DIP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA,IDA 11374908
GO:0005737 cytoplasm IEA,IDA 11374908
GO:0005794 Golgi apparatus ISS 11134006
GO:0005813 centrosome ISS 11134006
GO:0005815 microtubule organizing center IEA --
genes like me logo Genes that share ontologies with PDE4DIP: view

Pathways & Interactions for PDE4DIP Gene

SuperPathways for PDE4DIP Gene

No Data Available

SIGNOR curated interactions for PDE4DIP Gene

Activates:

Gene Ontology (GO) - Biological Process for PDE4DIP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0043623 cellular protein complex assembly ISS 11134006
genes like me logo Genes that share ontologies with PDE4DIP: view

No data available for Pathways by source for PDE4DIP Gene

Drugs & Compounds for PDE4DIP Gene

(1) Drugs for PDE4DIP Gene - From: HMDB

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
cyclic amp Experimental Pharma 0
genes like me logo Genes that share compounds with PDE4DIP: view

Transcripts for PDE4DIP Gene

Unigene Clusters for PDE4DIP Gene

Phosphodiesterase 4D interacting protein:
Representative Sequences:

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for PDE4DIP Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b · 8c · 8d ^ 9 ^ 10 ^ 11a · 11b · 11c ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17a · 17b ^ 18 ^
SP1: - - - - - - - -
SP2: - - -
SP3: - - -
SP4: - - -
SP5: - - -
SP6:
SP7:
SP8:
SP9: - - - - - - -
SP10:
SP11: - - -
SP12:
SP13: - -
SP14:
SP15:
SP16:

ExUns: 19 ^ 20 ^ 21 ^ 22 ^ 23 ^ 24 ^ 25a · 25b ^ 26 ^ 27 ^ 28 ^ 29a · 29b ^ 30 ^ 31a · 31b ^ 32 ^ 33a · 33b · 33c ^ 34 ^ 35a · 35b ^ 36 ^ 37 ^ 38 ^
SP1: - - - - - - - -
SP2: - - - - - - -
SP3: - - - - - - -
SP4: - - - -
SP5: - - - -
SP6: - - - -
SP7: - - - - -
SP8:
SP9:
SP10:
SP11:
SP12:
SP13:
SP14:
SP15:
SP16:

ExUns: 39 ^ 40 ^ 41 ^ 42 ^ 43 ^ 44 ^ 45 ^ 46 ^ 47a · 47b ^ 48 ^ 49a · 49b ^ 50a · 50b ^ 51 ^ 52 ^ 53 ^ 54 ^ 55a · 55b
SP1: - - -
SP2: - - -
SP3: - -
SP4:
SP5:
SP6:
SP7:
SP8: -
SP9:
SP10:
SP11:
SP12:
SP13:
SP14:
SP15:
SP16:

Relevant External Links for PDE4DIP Gene

GeneLoc Exon Structure for
PDE4DIP
ECgene alternative splicing isoforms for
PDE4DIP

Expression for PDE4DIP Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for PDE4DIP Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for PDE4DIP Gene

This gene is overexpressed in Muscle - Skeletal (x14.8) and Heart - Left Ventricle (x7.4).

Protein differential expression in normal tissues from HIPED for PDE4DIP Gene

This gene is overexpressed in Frontal cortex (46.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for PDE4DIP Gene



NURSA nuclear receptor signaling pathways regulating expression of PDE4DIP Gene:

PDE4DIP

SOURCE GeneReport for Unigene cluster for PDE4DIP Gene:

Hs.584841

mRNA Expression by UniProt/SwissProt for PDE4DIP Gene:

Q5VU43-MYOME_HUMAN
Tissue specificity: Highly expressed in heart and skeletal muscle and to a lower extent in brain and placenta.
genes like me logo Genes that share expression patterns with PDE4DIP: view

Primer Products

No data available for Protein tissue co-expression partners for PDE4DIP Gene

Orthologs for PDE4DIP Gene

This gene was present in the common ancestor of chordates.

Orthologs for PDE4DIP Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia PDE4DIP 35
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia PDE4DIP 34 35
  • 88.34 (n)
dog
(Canis familiaris)
Mammalia PDE4DIP 34 35
  • 87.65 (n)
mouse
(Mus musculus)
Mammalia Pde4dip 34 16 35
  • 83.13 (n)
rat
(Rattus norvegicus)
Mammalia Pde4dip 34
  • 82.38 (n)
oppossum
(Monodelphis domestica)
Mammalia PDE4DIP 35
  • 66 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia PDE4DIP 35
  • 50 (a)
OneToOne
chicken
(Gallus gallus)
Aves PDE4DIP 34 35
  • 62.22 (n)
lizard
(Anolis carolinensis)
Reptilia PDE4DIP 35
  • 45 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii si:ch211-242b18.1 34
  • 54.93 (n)
PDE4DIP 35
  • 31 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 18 (a)
OneToMany
Species where no ortholog for PDE4DIP was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for PDE4DIP Gene

ENSEMBL:
Gene Tree for PDE4DIP (if available)
TreeFam:
Gene Tree for PDE4DIP (if available)

Paralogs for PDE4DIP Gene

Paralogs for PDE4DIP Gene

genes like me logo Genes that share paralogs with PDE4DIP: view

Variants for PDE4DIP Gene

Sequence variations from dbSNP and Humsavar for PDE4DIP Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1002928 -- 148,952,088(-) CTCGC(C/G)GGGAG intron-variant, upstream-variant-2KB
rs10045281 -- 148,833,292(-) aaaaa(C/T)gataa intron-variant
rs10159285 -- 148,926,242(-) AATGA(C/T)ATTCC intron-variant
rs1020363 -- 148,894,534(-) CTGTC(A/G)GTACA intron-variant
rs1025970 -- 148,900,789(-) gcata(C/T)gggaa intron-variant

Structural Variations from Database of Genomic Variants (DGV) for PDE4DIP Gene

Variant ID Type Subtype PubMed ID
esv1942033 CNV deletion 18987734
esv1943257 CNV deletion 18987734
esv1963892 CNV deletion 18987734
esv2124797 CNV deletion 18987734
esv2191629 CNV deletion 18987734
esv23161 CNV gain 19812545
esv2391656 CNV deletion 18987734
esv2431887 CNV gain 19546169
esv2455158 CNV gain 19546169
esv2522501 CNV deletion 19546169
esv2582001 CNV deletion 19546169
esv2630464 CNV gain 19546169
esv2649952 CNV deletion 19546169
esv2670878 CNV deletion 23128226
esv27392 CNV gain 19812545
esv2761299 CNV gain+loss 21179565
esv2761854 CNV gain 21179565
esv2762189 CNV gain 21179565
esv2849902 CNV deletion 24192839
esv2850013 CNV deletion 24192839
esv2874901 CNV duplication 24192839
esv32934 CNV gain+loss 17666407
esv3352814 CNV duplication 20981092
esv3360116 CNV duplication 20981092
esv3361392 CNV insertion 20981092
esv3368223 CNV duplication 20981092
esv3380599 CNV duplication 20981092
esv3387252 CNV duplication 20981092
esv3414198 CNV duplication 20981092
esv3540300 CNV deletion 23714750
esv3540311 CNV deletion 23714750
esv3540333 CNV deletion 23714750
esv1010993 CNV deletion 20482838
esv1004968 CNV deletion 20482838
dgv92e212 CNV gain 25503493
dgv91e212 CNV gain 25503493
dgv90e212 CNV gain 25503493
dgv70n67 CNV gain 20364138
dgv66e199 CNV deletion 23128226
dgv44e214 CNV gain 21293372
dgv43e214 CNV gain 21293372
dgv327n100 CNV gain 25217958
dgv326n100 CNV gain 25217958
dgv325n100 CNV gain 25217958
dgv324n100 CNV gain 25217958
dgv323n100 CNV gain 25217958
dgv322n100 CNV loss 25217958
dgv321n100 CNV gain 25217958
dgv320n100 CNV gain 25217958
dgv319n100 CNV loss 25217958
dgv200e59 CNV duplication 20981092
dgv199e59 CNV duplication 20981092
dgv177n106 CNV duplication 24896259
dgv16n16 CNV deletion 17901297
esv3569897 CNV gain 25503493
esv3570008 CNV gain 25503493
esv3570675 CNV gain 25503493
esv3578141 CNV loss 25503493
esv3578142 CNV loss 25503493
esv3587397 CNV gain 21293372
esv3587402 CNV loss 21293372
esv3587404 CNV loss 21293372
esv3587405 CNV gain 21293372
esv6218 CNV loss 19470904
esv6514 CNV gain 19470904
esv6817 CNV loss 19470904
esv7052 CNV loss 19470904
esv7067 CNV loss 19470904
esv7886 CNV gain 19470904
esv8887 CNV loss 19470904
esv9122 CNV gain 19470904
nsv1001908 CNV loss 25217958
nsv1003688 CNV gain 25217958
nsv1005055 CNV loss 25217958
nsv1005230 CNV gain 25217958
nsv1006036 CNV gain 25217958
nsv1009283 CNV gain 25217958
nsv1009955 CNV loss 25217958
nsv1011358 CNV loss 25217958
nsv1076337 CNV duplication 25765185
nsv1076338 CNV duplication 25765185
nsv1077615 CNV deletion 25765185
nsv1077617 CNV deletion 25765185
nsv1078719 CNV deletion 25765185
nsv1113166 CNV deletion 24896259
nsv1113167 CNV deletion 24896259
nsv1113168 CNV deletion 24896259
nsv1119721 CNV deletion 24896259
nsv1122397 CNV deletion 24896259
nsv1122398 CNV deletion 24896259
nsv1122399 CNV deletion 24896259
nsv1132304 CNV duplication 24896259
nsv1137807 CNV deletion 24896259
nsv1137808 CNV deletion 24896259
nsv1139498 CNV duplication 24896259
nsv1140265 OTHER inversion 24896259
nsv1146989 CNV duplication 26484159
nsv1148615 CNV duplication 26484159
nsv1151226 CNV duplication 26484159
nsv1151380 CNV duplication 26484159
nsv1152455 CNV duplication 26484159
nsv1153254 CNV duplication 26484159
nsv1161492 CNV deletion 26073780
nsv158975 CNV insertion 16902084
nsv2 CNV deletion 15895083
nsv2633 CNV deletion 18451855
nsv2644 CNV deletion 18451855
nsv498686 CNV loss 21111241
nsv509457 CNV insertion 20534489
nsv510962 OTHER complex 20534489
nsv511712 CNV loss 21212237
nsv514005 CNV gain 21397061
nsv8058 CNV loss 18304495
nsv8069 CNV gain 18304495
nsv819024 CNV gain 19587683
nsv821349 CNV duplication 20802225
nsv821620 CNV loss 15273396
nsv824365 CNV gain 20364138
nsv831315 CNV loss 17160897
nsv831326 CNV loss 17160897
nsv946244 CNV duplication 23825009
nsv946246 CNV duplication 23825009
nsv946248 CNV duplication 23825009
nsv946249 CNV duplication 23825009
nsv946250 CNV duplication 23825009
nsv946251 CNV duplication 23825009
nsv946252 CNV duplication 23825009
nsv946253 CNV duplication 23825009
nsv946952 CNV duplication 23825009
nsv950944 CNV duplication 24416366
nsv955904 CNV deletion 24416366
nsv957357 CNV deletion 24416366
nsv957358 CNV deletion 24416366
nsv957525 CNV deletion 24416366
nsv999288 CNV loss 25217958

Variation tolerance for PDE4DIP Gene

Residual Variation Intolerance Score: 100% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 19.35; 98.84% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for PDE4DIP Gene

Human Gene Mutation Database (HGMD)
PDE4DIP
SNPedia medical, phenotypic, and genealogical associations of SNPs for
PDE4DIP

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for PDE4DIP Gene

Disorders for PDE4DIP Gene

MalaCards: The human disease database

(2) MalaCards diseases for PDE4DIP Gene - From: DISEASES and GeneCards

Disorder Aliases PubMed IDs
eosinophilia
  • eosinophil count raised
peritoneum cancer
  • cancer of peritoneum
- elite association - COSMIC cancer census association via MalaCards

UniProtKB/Swiss-Prot

MYOME_HUMAN
  • Note=A chromosomal aberration involving PDE4DIP may be the cause of a myeloproliferative disorder (MBD) associated with eosinophilia. Translocation t(1;5)(q23;q33) that forms a PDE4DIP-PDGFRB fusion protein. {ECO:0000269 PubMed:12907457}.

Relevant External Links for PDE4DIP

Genetic Association Database (GAD)
PDE4DIP
Human Genome Epidemiology (HuGE) Navigator
PDE4DIP
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
PDE4DIP
genes like me logo Genes that share disorders with PDE4DIP: view

No data available for Genatlas for PDE4DIP Gene

Publications for PDE4DIP Gene

  1. Isolation of novel heart-specific genes using the BodyMap database. (PMID: 11374908) Soejima H. … Mukai T. (Genomics 2001) 3 4 22 64
  2. Characterization of cDNA clones in size-fractionated cDNA libraries from human brain. (PMID: 9455484) Seki N. … Ohara O. (DNA Res. 1997) 2 3 4 64
  3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 46 64
  4. Serum anti-myomegalin antibodies in patients with esophageal squamous cell carcinoma. (PMID: 17143517) Shimada H. … Hiwasa T. (Int. J. Oncol. 2007) 3 22 64
  5. Protein kinase A, Ca2+/calmodulin-dependent kinase II, and calcineurin regulate the intracellular trafficking of myopodin between the Z-disc and the nucleus of cardiac myocytes. (PMID: 17923693) Faul C. … Mundel P. (Mol. Cell. Biol. 2007) 3 22 64

Products for PDE4DIP Gene

Sources for PDE4DIP Gene

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