Aliases for PDE2A Gene
External Ids for PDE2A Gene
Previous GeneCards Identifiers for PDE2A Gene
GeneCards Summary for PDE2A Gene
PDE2A (Phosphodiesterase 2A) is a Protein Coding gene. Diseases associated with PDE2A include Retinitis Pigmentosa. Among its related pathways are GABAergic synapse and CREB Pathway. GO annotations related to this gene include protein homodimerization activity and calcium channel activity. An important paralog of this gene is PDE11A.
UniProtKB/Swiss-Prot for PDE2A Gene
Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes.
Isoform PDE2A2: Regulates Mitochondrial cAMP Levels and Respiration.
Phosphodiesterases (PDEs) are a family of phosphohydrolyases that catalyze the hydrolysis of 3' cyclic phosphate bonds in adenosine and/or guanine 3',5' cyclic monophosphate (cAMP and/or cGMP). PDEs regulate the second messengers by controlling their degradation.