Aliases for PDE2A Gene
External Ids for PDE2A Gene
Previous GeneCards Identifiers for PDE2A Gene
GeneCards Summary for PDE2A Gene
PDE2A (Phosphodiesterase 2A) is a Protein Coding gene. Diseases associated with PDE2A include Retinitis Pigmentosa. Among its related pathways are G alpha (s) signalling events and Response to elevated platelet cytosolic Ca2+. GO annotations related to this gene include protein homodimerization activity and calcium channel activity. An important paralog of this gene is PDE11A.
UniProtKB/Swiss-Prot for PDE2A Gene
Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes.
Isoform PDE2A2: Regulates Mitochondrial cAMP Levels and Respiration.
Phosphodiesterases (PDEs) are a family of phosphohydrolyases that catalyze the hydrolysis of 3' cyclic phosphate bonds in adenosine and/or guanine 3',5' cyclic monophosphate (cAMP and/or cGMP). PDEs regulate the second messengers by controlling their degradation.