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Aliases for PDE10A Gene

Aliases for PDE10A Gene

  • Phosphodiesterase 10A 2 3 5
  • CAMP And CAMP-Inhibited CGMP 3,5-Cyclic Phosphodiesterase 10A 2 3
  • DJ416F21.1 (Phosphodiesterase 10A) 3
  • Phosphodiesterase 10A1 (PDE10A1) 3
  • Phosphodiesterase 10A7 (PDE10A7) 3
  • 3,5 CAMP/CGMP Phosphodiesterase 3
  • EC 3.1.4.17 4
  • EC 3.1.4.35 4
  • LINC00473 3
  • HSPDE10A 3
  • PDE10A19 3
  • EC 3.1.4 61
  • ADSD2 3
  • IOLOD 3

External Ids for PDE10A Gene

Previous GeneCards Identifiers for PDE10A Gene

  • GC06M165097
  • GC06M165618
  • GC06M165653
  • GC06M165714
  • GC06M163202

Summaries for PDE10A Gene

Entrez Gene Summary for PDE10A Gene

  • The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase family. It plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This protein can hydrolyze both cAMP and cGMP to the corresponding nucleoside 5' monophosphate, but has higher affinity for cAMP, and is more efficient with cAMP as substrate. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Dec 2011]

GeneCards Summary for PDE10A Gene

PDE10A (Phosphodiesterase 10A) is a Protein Coding gene. Diseases associated with PDE10A include Dyskinesia, Limb And Orofacial, Infantile-Onset and Striatal Degeneration, Autosomal Dominant 2. Among its related pathways are Signaling by GPCR and Purine metabolism (KEGG). GO annotations related to this gene include 3,5-cyclic-nucleotide phosphodiesterase activity and cGMP binding. An important paralog of this gene is PDE11A.

UniProtKB/Swiss-Prot for PDE10A Gene

  • Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. Can hydrolyze both cAMP and cGMP, but has higher affinity for cAMP and is more efficient with cAMP as substrate. May play a critical role in regulating cAMP and cGMP levels in the striatum, a region of the brain that contributes to the control of movement and cognition.

Tocris Summary for PDE10A Gene

  • Phosphodiesterases (PDEs) are a family of phosphohydrolyases that catalyze the hydrolysis of 3' cyclic phosphate bonds in adenosine and/or guanine 3',5' cyclic monophosphate (cAMP and/or cGMP). PDEs regulate the second messengers by controlling their degradation.

Gene Wiki entry for PDE10A Gene

No data available for PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PDE10A Gene

Genomics for PDE10A Gene

Regulatory Elements for PDE10A Gene

Enhancers for PDE10A Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH06F165635 1 Ensembl ENCODE 24.8 +349.7 349687 3.0 TEAD4 NR2F2 PDE10A RNU6-730P LOC105378115 GC06P165548
GH06F165633 0.6 ENCODE 11.7 +352.0 352003 1.3 TRIM28 PDE10A RNU6-730P LOC105378115 GC06P165548
GH06F165632 0.2 Ensembl 11.7 +353.9 353903 0.2 GATA3 DPF2 TRIM28 PDE10A RNU6-730P LOC105378115 GC06P165548
GH06F165634 0.4 ENCODE 11.7 +354.1 354116 0.2 ZNF316 GATA3 DPF2 MAFK PDE10A RNU6-730P LOC105378115 GC06P165548
GH06F165703 0.7 Ensembl 11.1 +282.5 282454 0.4 ZFHX2 ZNF133 PDE10A RNU6-730P GC06M165719 LOC105378115
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around PDE10A on UCSC Golden Path with GeneCards custom track

Promoters for PDE10A Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001233215 -497 3001 ARID4B SIN3A BRCA1 ZNF2 ZNF48 GLIS2 ZNF143 ZNF202 SP3 REST

Genomic Location for PDE10A Gene

Chromosome:
6
Start:
165,327,287 bp from pter
End:
165,986,603 bp from pter
Size:
659,317 bases
Orientation:
Minus strand

Genomic View for PDE10A Gene

Genes around PDE10A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
PDE10A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PDE10A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PDE10A Gene

Proteins for PDE10A Gene

  • Protein details for PDE10A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9Y233-PDE10_HUMAN
    Recommended name:
    cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase 10A
    Protein Accession:
    Q9Y233
    Secondary Accessions:
    • Q6FHX1
    • Q9HCP9
    • Q9NTV4
    • Q9ULW9
    • Q9Y5T1

    Protein attributes for PDE10A Gene

    Size:
    779 amino acids
    Molecular mass:
    88412 Da
    Cofactor:
    Name=a divalent metal cation; Xref=ChEBI:CHEBI:60240;
    Quaternary structure:
    • Homodimer.
    SequenceCaution:
    • Sequence=AAD32596.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

    Three dimensional structures from OCA and Proteopedia for PDE10A Gene

    Alternative splice isoforms for PDE10A Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for PDE10A Gene

Selected DME Specific Peptides for PDE10A Gene

Q9Y233:
  • PIPMMDR
  • HDLDHRG

Post-translational modifications for PDE10A Gene

Domains & Families for PDE10A Gene

Gene Families for PDE10A Gene

Protein Domains for PDE10A Gene

Graphical View of Domain Structure for InterPro Entry

Q9Y233

UniProtKB/Swiss-Prot:

PDE10_HUMAN :
  • The tandem GAF domains bind cAMP, and regulate enzyme activity. The binding of cAMP stimulates enzyme activity.
  • Belongs to the cyclic nucleotide phosphodiesterase family.
Domain:
  • The tandem GAF domains bind cAMP, and regulate enzyme activity. The binding of cAMP stimulates enzyme activity.
  • Composed of a C-terminal catalytic domain containing two divalent metal sites and an N-terminal regulatory domain which contains one cyclic nucleotide-binding region.
  • Contains 2 GAF domains.
Family:
  • Belongs to the cyclic nucleotide phosphodiesterase family.
genes like me logo Genes that share domains with PDE10A: view

Function for PDE10A Gene

Molecular function for PDE10A Gene

GENATLAS Biochemistry:
cGMP,cAMP inhibited nucleotide phosphodiesterase class10A,predominantly expressed in the putamen and caudate nucleus and in the testis
UniProtKB/Swiss-Prot BiophysicochemicalProperties:
Kinetic parameters: KM=56 nM for cAMP {ECO:0000269 PubMed:17389385}; KM=4.4 uM for cGMP {ECO:0000269 PubMed:17389385}; Vmax=507 nmol/min/mg enzyme for cAMP {ECO:0000269 PubMed:17389385}; Vmax=1860 nmol/min/mg enzyme for cGMP {ECO:0000269 PubMed:17389385};
UniProtKB/Swiss-Prot CatalyticActivity:
Nucleoside 3,5-cyclic phosphate + H(2)O = nucleoside 5-phosphate.
UniProtKB/Swiss-Prot CatalyticActivity:
Guanosine 3,5-cyclic phosphate + H(2)O = guanosine 5-phosphate.
UniProtKB/Swiss-Prot EnzymeRegulation:
Inhibited by dipyridamole and moderately by IBMX. cAMP acts as an allosteric activator.
UniProtKB/Swiss-Prot Function:
Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. Can hydrolyze both cAMP and cGMP, but has higher affinity for cAMP and is more efficient with cAMP as substrate. May play a critical role in regulating cAMP and cGMP levels in the striatum, a region of the brain that contributes to the control of movement and cognition.

Enzyme Numbers (IUBMB) for PDE10A Gene

Gene Ontology (GO) - Molecular Function for PDE10A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003824 catalytic activity IEA --
GO:0004112 cyclic-nucleotide phosphodiesterase activity IEA --
GO:0004114 3,5-cyclic-nucleotide phosphodiesterase activity TAS 10373451
GO:0004115 3,5-cyclic-AMP phosphodiesterase activity TAS --
GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity IDA 19689430
genes like me logo Genes that share ontologies with PDE10A: view
genes like me logo Genes that share phenotypes with PDE10A: view

Animal Models for PDE10A Gene

MGI Knock Outs for PDE10A:

Animal Model Products

  • Taconic Biosciences Mouse Models for PDE10A

Inhibitory RNA Products

Flow Cytometry Products

No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for PDE10A Gene

Localization for PDE10A Gene

Subcellular locations from UniProtKB/Swiss-Prot for PDE10A Gene

Cytoplasm. Note=Located mostly to soluble cellular fractions.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for PDE10A Gene COMPARTMENTS Subcellular localization image for PDE10A gene
Compartment Confidence
cytosol 5
nucleus 2
cytoskeleton 1
endoplasmic reticulum 1
mitochondrion 1
peroxisome 1
plasma membrane 1

Gene Ontology (GO) - Cellular Components for PDE10A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IEA --
GO:0005829 cytosol TAS --
GO:0016020 membrane IEA --
GO:0043025 neuronal cell body IEA --
GO:0043204 perikaryon IEA --
genes like me logo Genes that share ontologies with PDE10A: view

Pathways & Interactions for PDE10A Gene

genes like me logo Genes that share pathways with PDE10A: view

Pathways by source for PDE10A Gene

UniProtKB/Swiss-Prot Q9Y233-PDE10_HUMAN

  • Pathway: Purine metabolism; 3,5-cyclic AMP degradation; AMP from 3,5-cyclic AMP: step 1/1.
  • Pathway: Purine metabolism; 3,5-cyclic GMP degradation; GMP from 3,5-cyclic GMP: step 1/1.

SIGNOR curated interactions for PDE10A Gene

Other effect:

Gene Ontology (GO) - Biological Process for PDE10A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006198 cAMP catabolic process IEA --
GO:0007165 signal transduction IEA --
GO:0008152 metabolic process IEA --
GO:0010738 regulation of protein kinase A signaling IEA --
GO:0043949 regulation of cAMP-mediated signaling IEA --
genes like me logo Genes that share ontologies with PDE10A: view

Drugs & Compounds for PDE10A Gene

(23) Drugs for PDE10A Gene - From: DrugBank, ApexBio, DGIdb, FDA Approved Drugs, HMDB, Tocris, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Dipyridamole Approved Pharma Inhibition, Inhibitor, inhibitor, Target Adenosine transport inhibitor 80
Papaverine Approved Pharma Target, inhibitor 17
Tofisopam Approved Pharma Target, inhibitor 2
Triflusal Approved Pharma Target, antagonist 6
Caffeine Approved Nutra Antagonist, Target, inhibitor, competitive A1 and A2B antagonist. CNS stimulant 380

(1) Additional Compounds for PDE10A Gene - From: Tocris

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
IBMX
Antagonist 28822-58-4

(5) Tocris Compounds for PDE10A Gene

Compound Action Cas Number
(R)-(-)-Rolipram PDE4 inhibitor. More active enantiomer of rolipram (Cat. No. 0905) 85416-75-7
IBMX PDE inhibitor (non-selective) 28822-58-4
MDL 12330A hydrochloride Adenylyl cyclase inhibitor; also cyclic nucleotide PDE inhibitor 40297-09-4
Rolipram PDE4 inhibitor 61413-54-5
Sildenafil citrate Orally active, potent PDE5 inhibitor 171599-83-0

(1) ApexBio Compounds for PDE10A Gene

Compound Action Cas Number
PF-2545920 PDE10A inhibitor,potent and selective 1292799-56-4
genes like me logo Genes that share compounds with PDE10A: view

Transcripts for PDE10A Gene

Unigene Clusters for PDE10A Gene

Phosphodiesterase 10A:
Representative Sequences:

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for PDE10A Gene

No ASD Table

Relevant External Links for PDE10A Gene

GeneLoc Exon Structure for
PDE10A
ECgene alternative splicing isoforms for
PDE10A

Expression for PDE10A Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for PDE10A Gene

mRNA differential expression in normal tissues according to GTEx for PDE10A Gene

This gene is overexpressed in Brain - Putamen (basal ganglia) (x12.4), Brain - Caudate (basal ganglia) (x10.2), and Brain - Nucleus accumbens (basal ganglia) (x6.0).

Protein differential expression in normal tissues from HIPED for PDE10A Gene

This gene is overexpressed in Lung (37.6) and Fetal Brain (26.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for PDE10A Gene



Protein tissue co-expression partners for PDE10A Gene

NURSA nuclear receptor signaling pathways regulating expression of PDE10A Gene:

PDE10A

SOURCE GeneReport for Unigene cluster for PDE10A Gene:

Hs.348762

mRNA Expression by UniProt/SwissProt for PDE10A Gene:

Q9Y233-PDE10_HUMAN
Tissue specificity: Abundant in the putamen and caudate nucleus regions of brain and testis, moderately expressed in the thyroid gland, pituitary gland, thalamus and cerebellum.
genes like me logo Genes that share expression patterns with PDE10A: view

Primer Products

Orthologs for PDE10A Gene

This gene was present in the common ancestor of animals.

Orthologs for PDE10A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia PDE10A 34 35
  • 99.54 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia PDE10A 35
  • 94 (a)
OneToOne
dog
(Canis familiaris)
Mammalia PDE10A 34 35
  • 91.77 (n)
cow
(Bos Taurus)
Mammalia PDE10A 34 35
  • 87.29 (n)
mouse
(Mus musculus)
Mammalia Pde10a 34 16 35
  • 86.38 (n)
rat
(Rattus norvegicus)
Mammalia Pde10a 34
  • 85.82 (n)
oppossum
(Monodelphis domestica)
Mammalia PDE10A 35
  • 70 (a)
OneToOne
chicken
(Gallus gallus)
Aves PDE10A 34 35
  • 83.29 (n)
lizard
(Anolis carolinensis)
Reptilia PDE10A 35
  • 80 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia pde10a 34
  • 78.15 (n)
zebrafish
(Danio rerio)
Actinopterygii pde10a 34 35
  • 76.65 (n)
zgc56689 34
worm
(Caenorhabditis elegans)
Secernentea pde-5 34 35
  • 51.69 (n)
C32E12.2 36
  • 47 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 43 (a)
OneToOne
Species where no ortholog for PDE10A was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for PDE10A Gene

ENSEMBL:
Gene Tree for PDE10A (if available)
TreeFam:
Gene Tree for PDE10A (if available)

Paralogs for PDE10A Gene

Paralogs for PDE10A Gene

(3) SIMAP similar genes for PDE10A Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with PDE10A: view

Variants for PDE10A Gene

Sequence variations from dbSNP and Humsavar for PDE10A Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs778899140 Dyskinesia, limb and orofacial, infantile-onset (IOLOD) [MIM:616921], Pathogenic 165,450,268(+) GTTCA(C/T)AGAGG nc-transcript-variant, reference, missense, utr-variant-5-prime
VAR_076799 Dyskinesia, limb and orofacial, infantile-onset (IOLOD) [MIM:616921]
VAR_076800 Striatal degeneration, autosomal dominant 2 (ADSD2) [MIM:616922]
VAR_076801 Striatal degeneration, autosomal dominant 2 (ADSD2) [MIM:616922]
rs875989839 Pathogenic 165,450,242(-) AAATA(C/G)GTAAG nc-transcript-variant, reference, missense, utr-variant-5-prime

Structural Variations from Database of Genomic Variants (DGV) for PDE10A Gene

Variant ID Type Subtype PubMed ID
dgv399n21 CNV gain 19592680
dgv790n27 CNV loss 19166990
esv1728655 CNV insertion 17803354
esv25375 CNV loss 19812545
esv2636877 CNV insertion 19546169
esv275086 CNV loss 21479260
esv2762630 CNV loss 21179565
esv2762631 CNV gain 21179565
esv2763609 CNV loss 21179565
esv33295 CNV gain 17666407
esv3571526 CNV loss 25503493
esv3571527 CNV loss 25503493
esv3571528 CNV loss 25503493
esv3611618 CNV loss 21293372
esv3611619 CNV gain 21293372
esv3611620 CNV loss 21293372
esv3611621 CNV loss 21293372
esv3611622 CNV loss 21293372
esv3611623 CNV gain 21293372
nsv1074444 CNV deletion 25765185
nsv1114895 CNV deletion 24896259
nsv464136 CNV loss 19166990
nsv472065 CNV novel sequence insertion 20440878
nsv478672 CNV novel sequence insertion 20440878
nsv508438 CNV deletion 20534489
nsv510061 OTHER sequence alteration 20534489
nsv522249 CNV loss 19592680
nsv523862 CNV loss 19592680
nsv523973 CNV loss 19592680
nsv5586 CNV deletion 18451855
nsv5588 CNV insertion 18451855
nsv605245 CNV gain 21841781
nsv605252 CNV loss 21841781
nsv605253 CNV loss 21841781
nsv605254 CNV loss 21841781
nsv818468 CNV gain 17921354
nsv823925 CNV gain 20364138
nsv830863 CNV gain 17160897

Variation tolerance for PDE10A Gene

Residual Variation Intolerance Score: 14.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.37; 26.97% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for PDE10A Gene

Human Gene Mutation Database (HGMD)
PDE10A
SNPedia medical, phenotypic, and genealogical associations of SNPs for
PDE10A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for PDE10A Gene

Disorders for PDE10A Gene

MalaCards: The human disease database

(4) MalaCards diseases for PDE10A Gene - From: ClinVar, Swiss-Prot, DISEASES, Novoseek, and GeneCards

- elite association - COSMIC cancer census association via MalaCards

UniProtKB/Swiss-Prot

PDE10_HUMAN
  • Dyskinesia, limb and orofacial, infantile-onset (IOLOD) [MIM:616921]: An autosomal recessive, early-onset hyperkinetic movement disorder characterized by axial hypotonia, dyskinesia of the limbs and trunk, orofacial dyskinesia, drooling, and dysarthria. The severity of the hyperkinesis is variable. {ECO:0000269 PubMed:27058446}. Note=The disease is caused by mutations affecting the gene represented in this entry.
  • Striatal degeneration, autosomal dominant 2 (ADSD2) [MIM:616922]: An autosomal dominant disorder characterized by striatal degeneration and dysfunction of basal ganglia, resulting in hyperkinesis. {ECO:0000269 PubMed:27058447}. Note=The disease is caused by mutations affecting the gene represented in this entry.

Relevant External Links for PDE10A

Genetic Association Database (GAD)
PDE10A
Human Genome Epidemiology (HuGE) Navigator
PDE10A
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
PDE10A
genes like me logo Genes that share disorders with PDE10A: view

No data available for Genatlas for PDE10A Gene

Publications for PDE10A Gene

  1. Cloning and characterization of a novel human phosphodiesterase that hydrolyzes both cAMP and cGMP (PDE10A). (PMID: 10373451) Fujishige K. … Omori K. (J. Biol. Chem. 1999) 2 3 4 25 64
  2. The human phosphodiesterase PDE10A gene genomic organization and evolutionary relatedness with other PDEs containing GAF domains. (PMID: 10998054) Fujishige K. … Omori K. (Eur. J. Biochem. 2000) 3 4 22 64
  3. Isolation and characterization of PDE10A, a novel human 3',5'-cyclic nucleotide phosphodiesterase. (PMID: 10393245) Loughney K. … Florio V.A. (Gene 1999) 3 4 22 64
  4. De Novo Mutations in PDE10A Cause Childhood-Onset Chorea with Bilateral Striatal Lesions. (PMID: 27058447) Mencacci N.E. … Bhatia K.P. (Am. J. Hum. Genet. 2016) 3 4 64
  5. Biallelic Mutations in PDE10A Lead to Loss of Striatal PDE10A and a Hyperkinetic Movement Disorder with Onset in Infancy. (PMID: 27058446) Diggle C.P. … Brandon N.J. (Am. J. Hum. Genet. 2016) 3 4 64

Products for PDE10A Gene

Sources for PDE10A Gene

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