Aliases for PDCD2 Gene
External Ids for PDCD2 Gene
Previous GeneCards Identifiers for PDCD2 Gene
This gene encodes a nuclear protein expressed in a variety of tissues. Expression of this gene has been shown to be repressed by B-cell CLL/lymphoma 6 (BCL6), a transcriptional repressor required for lymph node germinal center development, suggesting that BCL6 regulates apoptosis by its effects on this protein. Alternative splicing results in multiple transcript variants and pseudogenes have been identified on chromosomes 9 and 12. [provided by RefSeq, Dec 2010]
GeneCards Summary for PDCD2 Gene
PDCD2 (Programmed Cell Death 2) is a Protein Coding gene. Diseases associated with PDCD2 include Chronic Fatigue Syndrome. Among its related pathways are TNF-alpha/NF-kB Signaling Pathway. GO annotations related to this gene include enzyme binding. An important paralog of this gene is PDCD2L.
UniProtKB/Swiss-Prot for PDCD2 Gene
May be a DNA-binding protein with a regulatory function. May play an important role in cell death and/or in regulation of cell proliferation.