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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

PDC Gene

protein-coding   GIFtS: 59
GCID: GC01M186412

Phosducin

Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
phosducin1 2     PhLP2
33 KDa Phototransducing Protein2 3     G Beta Gamma Binding Protein2
PHD2 3     Phosducin-Like Orphan Protein2
MEKA2     Protein MEKA3
PhLOP2     

External Ids:    HGNC: 87591   Entrez Gene: 51322   Ensembl: ENSG000001167037   OMIM: 1714905   UniProtKB: P209413   

Export aliases for PDC gene to outside databases

Previous GC identifers: GC01M183938 GC01M181840 GC01M182932 GC01M183651 GC01M183144 GC01M184679 GC01M157647


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for PDC Gene:
This gene encodes a phosphoprotein, which is located in the outer and inner segments of the rod cells in the
retina. This protein may participate in the regulation of visual phototransduction or in the integration of
photoreceptor metabolism. It modulates the phototransduction cascade by interacting with the beta and gamma
subunits of the retinal G-protein transducin. This gene is a potential candidate gene for retinitis pigmentosa
and Usher syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been
identified. (provided by RefSeq, Jul 2008)

GeneCards Summary for PDC Gene: 
PDC (phosducin) is a protein-coding gene. Diseases associated with PDC include familial paroxysmal nonkinesigenic dyskinesia, and usher syndrome type ii, and among its related super-pathways are Olfactory Signaling Pathway. GO annotations related to this gene include phospholipase inhibitor activity. An important paralog of this gene is PDCL2.

UniProtKB/Swiss-Prot: PHOS_HUMAN, P20941
Function: May participate in the regulation of visual phototransduction or in the integration of photoreceptor
metabolism. Inhibits the transcriptional activation activity of the cone-rod homeobox CRX

Gene Wiki entry for PDC (Phosducin) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.2  NT_004487.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the PDC gene promoter:
         CREB   p53   deltaCREB   HNF-4alpha2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidPDC promoter sequence
   Search SABiosciences Chromatin IP Primers for PDC

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PDC


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q25.2   Ensembl cytogenetic band:  1q31.1   HGNC cytogenetic band: 1q25.2

PDC Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PDC gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M186412:  view genomic region     (about GC identifiers)

Start:
186,412,698 bp from pter      End:
186,430,254 bp from pter
Size:
17,557 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: PHOS_HUMAN, P20941 (See protein sequence)
Recommended Name: Phosducin  
Size: 246 amino acids; 28246 Da
Subunit: Forms a complex with the beta and gamma subunits of the GTP-binding protein, transducin. Interacts with
CRX
Subcellular location: Cytoplasm, cytosol. Cell projection, cilium, photoreceptor outer segment. Photoreceptor
inner segment. Nucleus. Note=Outer and inner segments of the rod cells
Subcellular location: Isoform 2: Nucleus
Secondary accessions: Q14816 Q9UP22
Alternative splicing: 2 isoforms:  P20941-1   P20941-2   

Explore the universe of human proteins at neXtProt for PDC: NX_P20941

Explore proteomics data for PDC at MOPED 

Post-translational modifications:

  • UniProtKB: Light-induced changes in cyclic nucleotide levels modulate the phosphorylation of this protein by cAMP kinase
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P20941

  • PDC Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    PDC Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_002588.3  NP_072098.1  

    ENSEMBL proteins: 
     ENSP00000375855   ENSP00000422775   ENSP00000342033   ENSP00000411564  

    Human Recombinant Protein Products for PDC: 
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    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for PDC 

    Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001750photoreceptor outer segment IEA--
    GO:0001917photoreceptor inner segment IEA--
    GO:0005634nucleus IDA--
    GO:0005737cytoplasm IDA--
    GO:0005829cytosol IEA--

    PDC for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    4 InterPro protein domains:
     IPR023196 Phosducin_N_dom
     IPR001200 Phosducin
     IPR012336 Thioredoxin-like_fold
     IPR024253 Phosducin_thioredoxin-like_dom

    Graphical View of Domain Structure for InterPro Entry P20941

    ProtoNet protein and cluster: P20941

    1 Blocks protein domain: IPB001200 Phosducin signature

    UniProtKB/Swiss-Prot: PHOS_HUMAN, P20941
    Similarity: Belongs to the phosducin family


    PDC for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: PHOS_HUMAN, P20941
    Function: May participate in the regulation of visual phototransduction or in the integration of photoreceptor
    metabolism. Inhibits the transcriptional activation activity of the cone-rod homeobox CRX

         Genatlas biochemistry entry for PDC:
    phosducin,expressed in rod and cone photoreceptors and pinealocytes

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004859phospholipase inhibitor activity TAS7961975
         
    PDC for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for PDC:
     Increased gamma-H2AX phosphory 

         6 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Pdc):
     cardiovascular system  homeostasis/metabolism  muscle  nervous system  renal/urinary system 
     vision/eye 

    PDC for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-outs for PDC: Pdctm1Vya Pdctm1Luhe

       inGenious Targeting Laboratory - Custom generated mouse model solutions for PDC 
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for PDC About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Olfactory transduction
    Olfactory transduction0.81

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1         Kegg Pathway  (Kegg details for PDC):
        Olfactory transduction


    PDC for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for PDC

    STRING Interaction Network Preview (showing 5 interactants - click image to see 13)

    5/16 Interacting proteins for PDC (P209413 ENSP000003758554) via UniProtKB, MINT, STRING, and/or I2D (see all 16)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PRKACAP176123, ENSP000003095914I2D: score=1 STRING: ENSP00000309591
    ADRBK1P250983, ENSP000003122624I2D: score=2 STRING: ENSP00000312262
    CRXO431863, ENSP000002219964I2D: score=1 STRING: ENSP00000221996
    YWHAZP631043, ENSP000003095034I2D: score=1 STRING: ENSP00000309503
    EIF3IQ133473I2D: score=1 
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007186G-protein coupled receptor signaling pathway TAS7961975
    GO:0007601visual perception IEA--
    GO:0007602phototransduction TAS8288249

    PDC for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    PDC for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for PDC (PHOS)

    2 HMDB Compounds for PDC    About this table
    CompoundSynonyms CAS #PubMed Ids
    Cyclic AMPCyclic AMP (see all 19)60-92-4--
    Guanosine triphosphate5'-GTP (see all 10)86-01-1--

    1 DrugBank Compound for PDC    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    FARNESYL-- --target--10592235

    10/12 Novoseek inferred chemical compound relationships for PDC gene (see all 12)    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    etorphine 74.1 1 10443588 (1)
    pge1 21.9 7 9496706 (4), 9593987 (2)
    gdp 20.3 5 9545273 (2), 9606021 (2)
    gtp 18.2 2 9545273 (2)
    cyclic amp 16.1 2 11193104 (1), 1538828 (1)
    adenylate 12.4 4 9496706 (2), 10371466 (1), 1538828 (1)
    phospholipid 0 1 8168616 (1)
    lipid 0 1 7890702 (1)
    calcium 0 2 10328271 (1), 8643657 (1)
    arginine 0 2 16421094 (1)

    Search CenterWatch for drugs/clinical trials and news about PDC / PHOS

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for PDC gene (3 alternative transcripts): 
    NM_002597.4  NM_022576.3  NM_022577.1  

    Unigene Cluster for PDC:

    Phosducin
    Hs.654381  [show with all ESTs]
    Unigene Representative Sequence: NM_002597
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000391997(uc001gsa.3) ENST00000497198(uc001grz.3) ENST00000340129
    ENST00000456239
    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
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    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate PDC
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    Inhib. RNA
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    Sirion Biotech Customized lentivirus for stable overexpression of PDC 
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    Additional mRNA sequence: 

    AF076464.1 BC093839.1 BC112134.1 M33478.1 

    3 DOTS entries:

    DT.97864192  DT.92010896  DT.97864193 

    9 AceView cDNA sequences:

    NM_002597 BM674109 NM_022576 BM715757 AF076464 M33478 AF076465 AF076463 
    AL712565 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    PDC expression in normal human tissues (normalized intensities)      PDC embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGAAAATAAA
    PDC Expression
    About this image


    PDC expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/1 selected tissues (see all 1) fully expand
     
     Eye (Sensory Organs)
             Mature Rod Cells Outer Nuclear Layer

    See PDC Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for PDC

    SOURCE GeneReport for Unigene cluster: Hs.654381
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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for PDC gene from 6/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Pdc1 , 5 phosducin1, 5 86.34(n)1
    88.93(a)1
      1 (63.84 cM)5
    200281  NM_001159730.11  NP_001153202.11 
     1503194175 
    chicken
    (Gallus gallus)
    Aves PDC1 phosducin 76.15(n)
    77.24(a)
      429078  XM_426634.3  XP_426634.2 
    lizard
    (Anolis carolinensis)
    Reptilia PDC6
    Uncharacterized protein
    70(a)
    1 ↔ 1
    GL343203.1(2379564-2388905)
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.269502 Danio rerio cDNA clone IMAGE4144042, partial cds 75.74(n)    BC060908.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG76506
    --
    27(a)
    1 → many
    3L(15601807-15603486)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes PLP26
    Essential protein that interacts with the CCT (cha...
    15(a)
    1 → many
    XV(846269-847129)


    ENSEMBL Gene Tree for PDC (if available)
    TreeFam Gene Tree for PDC (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for PDC gene
    PDCL22  PDCL32  PDCL2  
    1 SIMAP similar gene for PDC using alignment to 2 protein entries:     PHOS_HUMAN (see all proteins):
    PDCL

    PDC for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/379 SNPs in PDC are shown (see all 379)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs711048621,2
    C--157659472(-) TTTTT-/T/TTTTT
    TTTTTTTTTT
    AGTAG
    2 -- int1 cds11NA 2
    rs2005212081,2
    C--157659560(+) GGGAG-/CTG   
       AGGCA
    TGAGG
    1 -- int10--------
    rs120667131,2
    F--157659581(+) gcgtaG/Aacctg 1 -- int12Minor allele frequency- A:0.50NA 4
    rs1924637871,2
    --157659597(+) CGGAGC/TTTGCA 1 -- int10--------
    rs1440563061,2
    C--157663435(+) GTGTG-/TGTAT 
     ATATATA
    TATAT
    1 -- int10--------
    rs721356301,2
    C--157663437(+) GTGTG-/TATATA
            
    TATAT
    1 -- int10--------
    rs715169621,2
    C--157663438(+) TGTGTG/ATATAT 1 -- int12Minor allele frequency- A:0.00NA 4
    rs2011716911,2
    C--157663444(+) TATATA/GTATAT 1 -- int10--------
    rs351301461,2
    C--157665450(+) TCCAT-/CTTTTC 1 -- us2k10--------
    rs2002422951,2
    C--157665450(+) TCCATC/TTTTTC 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for PDC (186412698 - 186430254 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for PDC: --

    Locus Specific Mutation Databases (LSDB): PDC
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing PDC
    DNA2.0 Custom Variant and Variant Library Synthesis for PDC

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 171490    OMIM disorders: --

    11 diseases for PDC:    About MalaCards
    familial paroxysmal nonkinesigenic dyskinesia    usher syndrome type ii    usher syndrome    retinitis pigmentosa
    retinitis    rhinitis    allergic rhinitis    neuroblastoma
    hypertension    prostate cancer    prostatitis

    3 diseases from the University of Copenhagen DISEASES database for PDC:
    Hypersensitivity reaction type I disease     Allergic rhinitis     Asthma

    PDC for disorders           About GeneDecksing

    3 Novoseek inferred disease relationships for PDC gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    retinitis pigmentosa 37 5 8288249 (1), 14758335 (1), 8646891 (1)
    glioma 10.5 2 9593987 (1), 9496706 (1)
    atrophy 2.46 3 9820795 (1), 18724412 (1)

    Genetic Association Database (GAD): PDC
    Human Genome Epidemiology (HuGE) Navigator: PDC (8 documents)

    Export disorders for PDC gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for PDC gene, integrated from 9 sources (see all 113):
    (articles sorted by number of sources associating them with PDC)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Assignment of the phosducin (PDC) gene to human chromosome 1q25-1q32.1 by somatic cell hybridization and in situ hybridization. (PubMed id 8288249)1, 3, 9 Sparkes R.S....Bateman J.B. (1993)
    2. Mutation screening of the phosducin gene PDC in patients with retinitis pigmentosa and allied diseases. (PubMed id 14758335)1, 4, 9 Nishiguchi K.M....Dryja T.P. (2004)
    3. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    4. Modulation of CRX transactivation activity by phosducin isoforms. (PubMed id 10866677)1, 2 Zhu X. and Craft C.M. (2000)
    5. Isolation and analysis of the human MEKA gene encoding a retina- specific protein. (PubMed id 2383274)1, 2 Watanabe Y.... Kuo C.H. (1990)
    6. Analysis of the human, bovine and rat 33-kDa proteins and cDNA in retina and pineal gland. (PubMed id 2210381)1, 2 Abe T....Shinohara T. (1990)
    7. SUMO-1 controls the protein stability and the biological function of phosducin. (PubMed id 16421094)1, 9 Klenk C....Lohse M.J. (2006)
    8. Phosphorylation of phosducin and phosducin-like protein by G protein-coupled receptor kinase 2. (PubMed id 10884381)1, 9 Ruiz-Gomez A....Mayor F. (2000)
    9. Phosducin, potential role in modulation of olfactory signaling. (PubMed id 9020189)1, 9 Boekhoff I....Lefkowitz R.J. (1997)
    10. PhLPs and PhLOPs in the phosducin family of G beta gamma binding proteins. (PubMed id 9843381)1, 9 Craft C.M....Lolley R.N. (1998)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 5132 HGNC: 8759 AceView: PDC Ensembl:ENSG00000116703 euGenes: HUgn5132
    ECgene: PDC Kegg: 5132 H-InvDB: PDC

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for PDC Pharmacogenomics, SNPs, Pathways
    Mutations of the PDC genehttp://www.retina-international.org/files/sci-news/pdcmut.htm

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for PDC gene:
    Search GeneIP for patents involving PDC

    GeneCards and IP:
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