Aliases for PDC Gene
External Ids for PDC Gene
Previous GeneCards Identifiers for PDC Gene
This gene encodes a phosphoprotein, which is located in the outer and inner segments of the rod cells in the retina. This protein may participate in the regulation of visual phototransduction or in the integration of photoreceptor metabolism. It modulates the phototransduction cascade by interacting with the beta and gamma subunits of the retinal G-protein transducin. This gene is a potential candidate gene for retinitis pigmentosa and Usher syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
GeneCards Summary for PDC Gene
PDC (Phosducin) is a Protein Coding gene. Diseases associated with PDC include paroxysmal nonkinesigenic dyskinesia and usher syndrome type ii. GO annotations related to this gene include phospholipase inhibitor activity. An important paralog of this gene is PDCL.
UniProtKB/Swiss-Prot for PDC Gene
May participate in the regulation of visual phototransduction or in the integration of photoreceptor metabolism. Inhibits the transcriptional activation activity of the cone-rod homeobox CRX.