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PCMTD2 Gene

protein-coding   GIFtS: 41
GCID: GC20P062887

Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase...

(Previous name: chromosome 20 open reading frame 36)
(Previous symbol: C20orf36)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase Domain
Containing 21 2
C20orf361 2 3
Chromosome 20 Open Reading Frame 361
Protein-L-Isoaspartate O-Methyltransferase Domain-Containing Protein 22

External Ids:    HGNC: 158821   Entrez Gene: 552512   Ensembl: ENSG000002038807   UniProtKB: Q9NV793   

Export aliases for PCMTD2 gene to outside databases

Previous GC identifers: GC20P062358 GC20P059616


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for PCMTD2 Gene:
PCMTD2 (protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2) is a protein-coding gene. GO annotations related to this gene include protein-L-isoaspartate (D-aspartate) O-methyltransferase activity. An important paralog of this gene is PCMTD1.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Regulatory transcription factor binding sites in the PCMTD2 gene promoter:
         AML1a   POU3F1   FOXO3   CUTL1   GATA-2   Gfi-1   FOXO3b   FOXO3a   SEF-1 (1)   LyF-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidPCMTD2 promoter sequence
   Search Chromatin IP Primers for PCMTD2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat PCMTD2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20q13.33   Ensembl cytogenetic band:  20q13.33   HGNC cytogenetic band: 20q13.33

PCMTD2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PCMTD2 gene location

GeneLoc information about chromosome 20         GeneLoc Exon Structure

GeneLoc location for GC20P062887:  view genomic region     (about GC identifiers)

Start:
62,887,048 bp from pter      End:
62,926,855 bp from pter
Size:
39,808 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: PCMD2_HUMAN, Q9NV79 (See protein sequence)
Recommended Name: Protein-L-isoaspartate O-methyltransferase domain-containing protein 2  
Size: 361 amino acids; 41072 Da
Secondary accessions: E1P5H3 Q8IW60 Q9H4K2
Alternative splicing: 3 isoforms:  Q9NV79-1   Q9NV79-2   Q9NV79-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for PCMTD2: NX_Q9NV79

Explore proteomics data for PCMTD2 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys295
  • Modification sites at PhosphoSitePlus

  • See PCMTD2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001098395.1  NP_060727.2  

    ENSEMBL proteins: 
     ENSP00000358773   ENSP00000477398   ENSP00000476878   ENSP00000307854   ENSP00000477252  
     ENSP00000477110   ENSP00000477240   ENSP00000476726   ENSP00000299468  

    PCMTD2 Human Recombinant Protein Products:

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    OriGene Protein Over-expression Lysate for PCMTD2
    OriGene Custom MassSpec
    OriGene Custom Protein Services for PCMTD2
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    Novus Biologicals PCMTD2 Protein
    Novus Biologicals PCMTD2 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for PCMTD2

    PCMTD2 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    Browse OriGene Antibodies
    OriGene Custom Antibody Services for PCMTD2
    Novus Biologicals PCMTD2 Antibodies
    Abcam antibodies for PCMTD2
    Cloud-Clone Corp. Antibodies for PCMTD2
    Search ThermoFisher Antibodies for PCMTD2
    LSBio Antibodies in human, mouse, rat for PCMTD2

    PCMTD2 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for PCMTD2
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for PCMTD2
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for PCMTD2
    Cloud-Clone Corp. CLIAs for PCMTD2


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR000682 PCMT

    Graphical View of Domain Structure for InterPro Entry Q9NV79

    ProtoNet protein and cluster: Q9NV79

    1 Blocks protein domain: IPB000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase

    UniProtKB/Swiss-Prot: PCMD2_HUMAN, Q9NV79
    Similarity: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase
    family


    PCMTD2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004719protein-L-isoaspartate (D-aspartate) O-methyltransferase activity IEA--
         
    PCMTD2 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for PCMTD2
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for PCMTD2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for PCMTD2
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for PCMTD2

    miRNA
    Products:
        
    miRTarBase miRNAs that target PCMTD2:
    hsa-mir-142-3p (MIRT021615), hsa-mir-23b-3p (MIRT023481)

    Block miRNA regulation of human, mouse, rat PCMTD2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate PCMTD2 (see all 12):
    hsa-miR-299-5p hsa-miR-3163 hsa-miR-607 hsa-miR-586 hsa-miR-548o hsa-miR-507 hsa-miR-218 hsa-miR-570
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for PCMTD2
    Predesigned siRNA for gene silencing in human, mouse, rat PCMTD2

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for PCMTD2

    Clone
    Products:
         
    OriGene clones in human, mouse for PCMTD2 (see all 13)
    OriGene ORF clones in mouse, rat for PCMTD2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): PCMTD2 (NM_018257)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for PCMTD2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PCMTD2

    Cell Line
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    GenScript Custom overexpressing Cell Line Services for PCMTD2
    Browse ESI BIO Cell Lines and PureStem Progenitors for PCMTD2 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PCMTD2


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    PCMD2_HUMAN, Q9NV79: Cytoplasm (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    nucleus2
    mitochondrion1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--

    PCMTD2 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for PCMTD2
    Interactions:

        Search GeneGlobe Interaction Network for PCMTD2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

    Selected Interacting proteins for PCMTD2 (ENSP000003078544) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CUL2ENSP000003638804STRING: ENSP00000363880
    TCEB1ENSP000002848114STRING: ENSP00000284811
    TCEB2ENSP000002623064STRING: ENSP00000262306
    UBCENSP000003448184STRING: ENSP00000344818
    MAPK3ENSP000002630254STRING: ENSP00000263025
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006464cellular protein modification process ----

    PCMTD2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for PCMTD2 (PCMD2)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for PCMTD2 gene (2 alternative transcripts): 
    NM_001104925.1  NM_018257.2  

    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000369758(uc002yim.4) ENST00000609372 ENST00000610196 ENST00000308824(uc002yil.4)
    ENST00000609764 ENST00000609297 ENST00000610074 ENST00000608844 ENST00000609818
    ENST00000266078 ENST00000299468
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat PCMTD2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate PCMTD2 (see all 12):
    hsa-miR-299-5p hsa-miR-3163 hsa-miR-607 hsa-miR-586 hsa-miR-548o hsa-miR-507 hsa-miR-218 hsa-miR-570
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for PCMTD2
    Predesigned siRNA for gene silencing in human, mouse, rat PCMTD2
    Clone
    Products:
         
    OriGene clones in human, mouse for PCMTD2 (see all 13)
    OriGene ORF clones in mouse, rat for PCMTD2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): PCMTD2 (NM_018257)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for PCMTD2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PCMTD2
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for PCMTD2
    OriGene qSTAR qPCR primer pairs in human, mouse for PCMTD2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat PCMTD2
      QuantiTect SYBR Green Assays in human, mouse, rat PCMTD2
      QuantiFast Probe-based Assays in human, mouse, rat PCMTD2

    Selected AceView cDNA sequences (see all 296):

    AI338764 BE882508 AI434331 BQ640464 AW960807 AA424320 BC032332 AK126700 
    AV751920 AA847416 AL039567 BU178592 BQ549676 CR603851 N48465 AA433945 
    AA741394 BG675029 AA421161 BU509848 BU508947 NM_018257 AA193670 BM668232 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    PCMTD2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    PCMTD2 Expression
    About this image

    PCMTD2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    PCMTD2 Protein Expression
        Custom PCR Arrays for PCMTD2
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for PCMTD2
    OriGene qSTAR qPCR primer pairs in human, mouse for PCMTD2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat PCMTD2
    QuantiTect SYBR Green Assays in human, mouse, rat PCMTD2
    QuantiFast Probe-based Assays in human, mouse, rat PCMTD2
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PCMTD2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for PCMTD2 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Pcmtd21 , 5 protein-L-isoaspartate (D-aspartate) O-methyltransferase more1, 5 84.49(n)1
    91.36(a)1
      2 (103.81 cM)5
    2458671  NM_153594.21  NP_705822.11 
     1818378545 
    chicken
    (Gallus gallus)
    Aves PCMTD21 protein-L-isoaspartate (D-aspartate) O-methyltransferase more 81.26(n)
    94.46(a)
      419248  XM_004947106.1  XP_004947163.1 
    lizard
    (Anolis carolinensis)
    Reptilia PCMTD26
    protein-L-isoaspartate (D-aspartate) O-methyltrans...
    91(a)
    1 ↔ 1
    4(154488811-154514504)
    African clawed frog
    (Xenopus laevis)
    Amphibia MGC533412 similar to chromosome 20 open reading frame 36 76.45(n)    BC044686.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1005367771 protein-L-isoaspartate O-methyltransferase domain-containing more 73.23(n)
    79.54(a)
      100536777  XM_003201174.2  XP_003201222.1 
    worm
    (Caenorhabditis elegans)
    Secernentea CELE_R119.51 CELE_R119.5 42.64(n)
    31.4(a)
      171631  NM_001261918.1  NP_001248847.1 


    ENSEMBL Gene Tree for PCMTD2 (if available)
    TreeFam Gene Tree for PCMTD2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for PCMTD2 gene
    PCMTD12  
    2 SIMAP similar genes for PCMTD2 using alignment to 9 protein entries:     PCMD2_HUMAN (see all proteins):
    PCMTD1    DKFZp666F248

    PCMTD2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for PCMTD2 (see all 520)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 20 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1895387281,2
    --62885069(+) CAAAGG/TTTGGA 2 -- us2k10--------
    rs1811522381,2
    --62885095(+) CACCAA/GGAGTT 2 -- us2k10--------
    rs1417946361,2
    --62885143(+) ATAACA/GAAGGA 2 -- us2k10--------
    rs1169938681,2
    C,F--62885205(+) AGAAAC/TTCCCC 2 -- us2k11Minor allele frequency- T:0.03NA 120
    rs1864454601,2
    --62885259(+) ATATCA/GTTATG 2 -- us2k10--------
    rs1472112001,2
    --62885328(+) GTAAAC/GTTACT 2 -- us2k10--------
    rs767765011,2
    C--62885372(+) TTAGTC/TATAGA 2 -- us2k10--------
    rs1407171151,2
    C--62885662(+) TTTAGA/GAGGAC 2 -- us2k10--------
    rs1173972791,2
    C,F--62885727(+) TGGGAC/TAGGGC 2 -- us2k11Minor allele frequency- T:0.01NA 120
    rs1157174921,2
    C,F--62885758(+) CGTGTC/ACCCTG 2 -- us2k11Minor allele frequency- A:0.08WA 118

    HapMap Linkage Disequilibrium report for PCMTD2 (62887048 - 62926855 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for PCMTD2:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv1549221CNV Deletion17803354
    esv1694737CNV Deletion17803354
    esv2447590CNV Deletion19546169
    nsv9834CNV Gain18304495
    nsv428381CNV Gain+Loss18775914
    dgv1347e1CNV Complex17122850

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing PCMTD2
    DNA2.0 Custom Variant and Variant Library Synthesis for PCMTD2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for PCMTD2 gene, integrated from 10 sources (see all 12):
    (articles sorted by number of sources associating them with PCMTD2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    3. The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (Nature 2001)
    4. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    5. Identification of novel ATP13A2 interactors and their role in I+-synuclein misfolding and toxicity. (PubMed id 22645275)1 Usenovic M....Krainc D. (Hum. Mol. Genet. 2012)
    6. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    7. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    8. Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics. (PubMed id 21145461)1 Bennett E.J....Harper J.W. (Cell 2010)
    9. Characterization of Cullin-box sequences that direct recruitment of Cul2-Rbx1 and Cul5-Rbx2 modules to Elongin BC-based ubiquitin ligases. (PubMed id 18187417)1 Mahrour N....Conaway J.W. (J. Biol. Chem. 2008)
    10. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 55251 HGNC: 15882 AceView: MYT1andC20orf36andLOC440773 Ensembl:ENSG00000203880 euGenes: HUgn55251
    ECgene: PCMTD2 H-InvDB: PCMTD2

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for PCMTD2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for PCMTD2 gene:
    Search GeneIP for patents involving PCMTD2

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