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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

PCLO Gene

protein-coding   GIFtS: 51
GCID: GC07M082383

piccolo presynaptic cytomatrix protein

(Previous name: piccolo (presynaptic cytomatrix protein) )
 Explore 5 diseases affiliated with
PCLO via our new
 Human Malady Compendium 
Biological research products
for PCLO
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Piccolo Presynaptic Cytomatrix Protein1 2     DKFZp779G12361
ACZ1 2 3     Aczonin3
Piccolo (Presynaptic Cytomatrix Protein)1 2     Protein Piccolo2
KIAA05591 3     Aczonin3

External Ids:    HGNC: 134061   Entrez Gene: 274452   Ensembl: ENSG000001864727   OMIM: 6049185   UniProtKB: Q9Y6V03   

Export aliases for PCLO gene to outside databases

Previous GC identifers: GC07M080985 GC07M082048 GC07M082061 GC07M081999 GC07M082094 GC07M082266 GC07M076984


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for PCLO:
The protein encoded by this gene is part of the presynaptic cytoskeletal matrix, which is involved in establishing
active synaptic zones and in synaptic vesicle trafficking. Variations in this gene have been associated with bipolar
disorder and major depressive disorder. Two transcript variants encoding different isoforms have been found for this
gene. (provided by RefSeq, Nov 2011)

UniProtKB/Swiss-Prot: PCLO_HUMAN, Q9Y6V0
Function: May act as a scaffolding protein involved in the organization of synaptic active zones and in synaptic
vesicle trafficking (By similarity)

Gene Wiki entry for PCLO


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NC_018918.1  NT_007933.15  NT_079595.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the PCLO gene promoter:
         E2F-3a   E2F-4   E2F-5   E2F-2   C/EBPalpha   AREB6   CHOP-10   E2F-1   E2F   PPAR-gamma2   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for PCLO

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PCLO


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q11.23-q21.3   Ensembl cytogenetic band:  7q21.11   HGNC cytogenetic band: 7q11.23-q21.3

PCLO Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PCLO gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07M082383:  view genomic region     (about GC identifiers)

Start:
82,383,321 bp from pter      End:
82,792,246 bp from pter
Size:
408,926 bases      Orientation:
minus strand

1 alternative location:
Chr7-,CRA_TCAG 81,715,437-82,124,409     

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: PCLO_HUMAN, Q9Y6V0 (See protein sequence)
Recommended Name: Protein piccolo  
Size: 5065 amino acids; 553277 Da
Subunit: Interacts with RABAC1/PRA1, RIMS2 and profilin (By similarity)
Subcellular location: Cell junction, synapse (By similarity). Note=Concentrated at the presynaptic side of synaptic
junctions (By similarity)
Sequence caution: Sequence=AAB97937.1; Type=Erroneous gene model prediction; Sequence=AAD21789.2; Type=Erroneous gene
model prediction;
1 PDB 3D structure from and Proteopedia for PCLO:
1UJD (3D)    
Secondary accessions: A4D1A7 A6NNX9 O43373 O60305 Q08E72 Q9BVC8 Q9UIV2 Q9Y6U9
Alternative splicing: 6 isoforms:  Q9Y6V0-1   Q9Y6V0-2   Q9Y6V0-3   Q9Y6V0-4   Q9Y6V0-5   Q9Y6V0-6   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for PCLO: NX_Q9Y6V0

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9Y6V0

  • PCLO Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_055325.2  NP_149015.2  

    ENSEMBL proteins: 
     ENSP00000334319   ENSP00000388393   ENSP00000404191   ENSP00000397928   ENSP00000393760  

    Human Recombinant Protein Products: 
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    Novus Biologicals PCLO Protein
    Novus Biologicals PCLO Lysate
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for PCLO

    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005856cytoskeleton NAS10508862
    GO:0008021synaptic vesicle IEA--
    GO:0016020membrane IEA--
    GO:0030054cell junction IEA--
    GO:0045202synapse ISS--


    PCLO for ontologies           About GeneDecksing



    PCLO Antibody Products: 
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    Uscn Antibodies for PCLO
    Search ThermoFisher Antibodies for PCLO

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    Uscn ELISAs and CLIAs for PCLO


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    PCLO for domains           About GeneDecksing

    5/8 InterPro domains/families (see all 8):
     IPR001565 Synaptotagmin
     IPR008899 Znf_piccolo
     IPR018029 C2_membr_targeting
     IPR013083 Znf_RING/FYVE/PHD
     IPR008973 C2_Ca/lipid-bd_dom_CaLB

    Graphical View of Domain Structure for InterPro Entry Q9Y6V0

    ProtoNet protein and cluster: Q9Y6V0

    2 Blocks protein families:
    IPB000008 C2 domain
    IPB001565 Synaptotagmin signature


    UniProtKB/Swiss-Prot: PCLO_HUMAN, Q9Y6V0
    Domain: C2 domain 1 is involved in binding calcium and phospholipids. Calcium binds with low affinity but with high
    specificity and induces a large conformational change
    Similarity: Contains 2 C2 domains
    Similarity: Contains 1 PDZ (DHR) domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: PCLO_HUMAN, Q9Y6V0
    Function: May act as a scaffolding protein involved in the organization of synaptic active zones and in synaptic
    vesicle trafficking (By similarity)

    miRNA
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    8/72 QIAGEN miScript miRNA Assays for microRNAs that regulate PCLO (see all 72):
    hsa-miR-548j hsa-miR-138-2* hsa-miR-409-5p hsa-miR-548a-5p hsa-miR-376c hsa-miR-3612 hsa-miR-761 hsa-miR-559
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    Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005215transporter activity IEA--
    GO:0005509calcium ion binding ISS--
    GO:0005515protein binding ----
    GO:0005522profilin binding ISS--
    GO:0005544calcium-dependent phospholipid binding ISS--


    PCLO for ontologies           About GeneDecksing


    Animal Models:
         Mouse knock-outs for PCLO: Pclotm1Sud Pclotm3.2Sud Pclotm3.3Sud
         4 MGI mutant phenotypes (inferred from 5 alleles(MGI details for Pclo):
     growth/size  mortality/aging  nervous system  normal 

    PCLO for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for PCLO

    5/10 Interacting proteins for PCLO (Q9Y6V02, 3) via UniProtKB, MINT, STRING, and/or I2D (see all 10)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ERC2O150833I2D: score=2 
    GIT1Q9Y2X73I2D: score=2 
    BSNQ9UPA53I2D: score=1 
    GIT2Q141613I2D: score=1 
    GRIA1P422613I2D: score=1 
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007010cytoskeleton organization ISS--
    GO:0016079synaptic vesicle exocytosis NAS10508862
    GO:0017157regulation of exocytosis IEA--
    GO:0019933cAMP-mediated signaling IEA--
    GO:0030073insulin secretion IEA--


    PCLO for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for PCLO

    1 HMDB Compound for PCLO    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--
    Search CenterWatch for drugs/clinical trials and news about PCLO 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for PCLO gene (2 alternative transcripts): 
    NM_014510.2  NM_033026.5  

    Unigene Cluster for PCLO:

    Piccolo presynaptic cytomatrix protein
    Hs.12376  [show with all ESTs]
    Unigene Representative Sequence: NM_033026
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000333891(uc003uhx.2 uc010lec.3) ENST00000432078 ENST00000423517(uc003uht.1 uc003uhu.1 uc003uhv.2)
    ENST00000426442 ENST00000413807 ENST00000456006 ENST00000437081 ENST00000461143


    miRNA
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    8/72 QIAGEN miScript miRNA Assays for microRNAs that regulate PCLO (see all 72):
    hsa-miR-548j hsa-miR-138-2* hsa-miR-409-5p hsa-miR-548a-5p hsa-miR-376c hsa-miR-3612 hsa-miR-761 hsa-miR-559
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for PCLO (see all 4)
    OriGene shRNA RFP: PCLO
    OriGene siRNA: PCLO
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    Clone
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PCLO
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PCLO

    Additional cDNA sequence: 

    AB011131.1 AK125999.1 AK297315.1 BC001304.1 BC108289.1 BC122565.1 BC125271.1 BX649041.1 
    CR749552.1 Y19188.1 

    17 DOTS entries:

    DT.213534  DT.91739661  DT.97838761  DT.100654980  DT.121128607  DT.100720980  DT.91673395  DT.40193031 
    DT.121100480  DT.440143  DT.91735847  DT.121048130  DT.121120115  DT.40249215  DT.92057798  DT.97815382 
    DT.97771837 

    24/74 AceView cDNA sequences (see all 74):

    NM_014510 AA319026 CD675028 AA973826 BM728943 T05362 NM_033026 BQ216059 
    CR612833 AK125999 BU177122 F10580 BG913494 AL157667 AB011131 AA715130 
    AA081672 AA604136 BM449664 AI018383 BC001304 BU176901 F12984 BU742965 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    PCLO expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CTTTTCTTTA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See PCLO Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for PCLO

    SOURCE GeneReport for Unigene cluster: Hs.12376
        SABiosciences Custom PCR Arrays for PCLO
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PCLO

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for PCLO gene from 4/14 species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves PCLO1 piccolo (presynaptic cytomatrix protein) 65.42(n)
    60.71(a)
      395319  XM_001231454.2  XP_001231455.2 
    lizard
    (Anolis carolinensis)
    Reptilia PCLO6
    --
    --
    70(a)
    24(a)
    1 ↔ 1
    possible ortholog
    5(87050733-87219563)
    5(87336208-87376966)
    zebrafish
    (Danio rerio)
    Actinopterygii si:dkey-108d22.41 si:dkey-108d22.4 55.36(n)
    51.11(a)
      100148002  XM_001921182.3  XP_001921217.3 
    worm
    (Caenorhabditis elegans)
    Secernentea F45E4.36
    Protein F45E4.3, isoform b
    23(a)
    1 → many
    IV(7619619-7628223)


    ENSEMBL Gene Tree for PCLO (if available)
    TreeFam Gene Tree for PCLO (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for PCLO gene
    BSN2  
    11 SIMAP similar genes for PCLO using alignment to 6 protein entries:     PCLO_HUMAN (see all proteins):
    DKFZp779G1236    LOC392742    DLG4    DOC2A    CHR11SYT    RIMS1
    SYTL2    RASA4    SYT1    SYT11    RPH3A

    PCLO for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/6892 NCBI SNPs in PCLO are shown (see all 6892    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs577226571,2
    C--82091657(+) TTGTT-/GTTATTAT 1 -- int11Minor allele frequency- GTT:0.00NA 2
    rs780278131,2
    C,--82382850(+) CTTTTC/TTTTTT 1 -- ds50010--------
    rs1901405661,2
    --82382855(+) CTTTTC/TTTTTT 1 -- ds50010--------
    rs1424205311,2
    --82382872(+) AAAGGC/TGATTC 1 -- ds50010--------
    rs1820523681,2
    --82382956(+) GACAAA/CTACAC 1 -- ds50010--------
    rs1875817891,2
    --82382997(+) TCAAGA/CAATTA 1 -- ds50010--------
    rs1165122711,2
    F,--82383015(+) TAAATC/TAGGAT 1 -- ds50011Minor allele frequency- T:0.03WA 118
    rs1155230731,2
    C,F,--82383154(+) ATTTAT/CGAAGC 1 -- ds50011Minor allele frequency- C:0.03WA 118
    rs1927930941,2
    --82383163(+) GCTATA/GCATTT 1 -- ds50010--------
    rs749788131,2
    C,F,--82383241(+) ATTTAC/TGATAC 1 -- ds50012Minor allele frequency- T:0.11WA EA 238

    HapMap Linkage Disequilibrium report for PCLO (82383321 - 82633321 bp, first 250kb of PCLO)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 7 variations for PCLO
         7 CNVs: 94656 82070 59424 100007 8571 37933 10198

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PCLO
    DNA2.0 Custom Variant and Variant Library Synthesis for PCLO

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    PCLO for disorders           About GeneDecksing

    OMIM gene information: 604918    OMIM disorders: --

    5 diseases for PCLO:    About MalaCards
    major depressive disorder    bipolar disorder    trigeminal neuralgia    insulin resistance
    cerebrovascular disease

    Human Genome Epidemiology (HuGE) Navigator: PCLO (8 documents)

    Export disorders for PCLO gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for PCLO gene, integrated from 9 sources (see all 31):
    (articles sorted by number of sources associating them with PCLO)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9628581)1, 2, 3 Nagase T....Ohara O. (1998)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. The DNA sequence of human chromosome 7. (PubMed id 12853948)1, 2 Hillier L.W.... Wilson R.K. (2003)
    4. Aczonin, a 550-kd putative scaffolding protein of presynaptic active zones, shares homology regions with rim and bassoon and binds profilin. (PubMed id 10508862)1, 2 Wang X....Kilimann M.W. (1999)
    5. Piccolo, a novel 420 kDa protein associated with the presynaptic cytomatrix. (PubMed id 8900486)1, 3 Cases-Langhoff C....Garner C.C. (1996)
    6. Genome-wide association for major depressive disorder: a possible role for the presynaptic protein piccolo. (PubMed id 19065144)1, 9 Sullivan P.F....Penninx B.W. (2009)
    7. Genotype distributions and allele frequencies of possi ble major depressive disorder-associated single nucleotide polymorphisms, cyclic adenosine monophosphate response element binding protein 1 rs4675690 and Piccol o rs2522833, in a Japanese population. (PubMed id 22293360)1 Inoue K....Itoh K. (2012)
    8. Gene expression and genetic variation data implicate PCLO in bipolar disorder. (PubMed id 21185011)1 Choi K.H....Webster M.J. (2011)
    9. Genome-wide association analysis of gender difference s in major depressive disorder in the Netherlands NESDA and NTR population-base d samples. (PubMed id 21621269)1 Aragam N....Pan Y. (2011)
    10. Meta-analysis of genome-wide association data of bipo lar disorder and major depressive disorder. (PubMed id 20351715)1 Liu Y....Sullivan P.F. (2010)

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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 27445 HGNC: 13406 AceView: PCLO Ensembl:ENSG00000186472 euGenes: HUgn27445
    ECgene: PCLO H-InvDB: PCLO

    (According to HUGE)
    About This Section
    HUGE: KIAA0559

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for PCLO Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for PCLO gene:
    Search GeneIP for patents involving PCLO

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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