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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

PCGF3 Gene

protein-coding   GIFtS: 45
GCID: GC04P000691

Polycomb Group Ring Finger 3

(Previous name: ring finger protein 3)
(Previous symbol: RNF3)
  Search for PCGF3
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Polycomb Group Ring Finger 31 2     RING Finger Protein 3A2 3
RNF31 2 3     DONG12
Ring Finger Protein 31 2     Polycomb Group RING Finger Protein 32
RNF3A2 3     

External Ids:    HGNC: 100661   Entrez Gene: 103362   Ensembl: ENSG000001856197   UniProtKB: Q3KNV83   

Export aliases for PCGF3 gene to outside databases


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for PCGF3 Gene:
The protein encoded by this gene contains a C3HC4 type RING finger, which is a motif known to be involved in
protein-protein interactions. The specific function of this protein has not yet been determined. (provided by
RefSeq, Jul 2008)

GeneCards Summary for PCGF3 Gene: 
PCGF3 (polycomb group ring finger 3) is a protein-coding gene. GO annotations related to this gene include protein binding and zinc ion binding. An important paralog of this gene is PCGF5.

UniProtKB/Swiss-Prot: PCGF3_HUMAN, Q3KNV8
Function: Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain
the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1
complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A
'Lys-119', rendering chromatin heritably changed in its expressibility




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000004.11  NT_037622.5  NC_018915.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the PCGF3 gene promoter:
         Max1   STAT1   NF-1   NF-1/L   Evi-1   HEN1   deltaCREB   ARP-1   TGIF   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidPCGF3 promoter sequence
   Search SABiosciences Chromatin IP Primers for PCGF3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PCGF3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4p16.3   Ensembl cytogenetic band:  4p16.3   HGNC cytogenetic band: 4p16.3

PCGF3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PCGF3 gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04P000691:  view genomic region     (about GC identifiers)

Start:
699,537 bp from pter      End:
764,428 bp from pter
Size:
64,892 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: PCGF3_HUMAN, Q3KNV8 (See protein sequence)
Recommended Name: Polycomb group RING finger protein 3  
Size: 242 amino acids; 28115 Da
Subunit: Component of a PRC1-like complex. Interacts with CBX6, CBX7 and CBX8
Subcellular location: Nucleus
Secondary accessions: D3DVN1 O15262
Alternative splicing: 2 isoforms:  Q3KNV8-1   Q3KNV8-2   

Explore the universe of human proteins at neXtProt for PCGF3: NX_Q3KNV8

Explore proteomics data for PCGF3 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q3KNV8

  • PCGF3 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    PCGF3 Protein Expression
    REFSEQ proteins: NP_006306.2  
    ENSEMBL proteins: 
     ENSP00000416279   ENSP00000354724   ENSP00000383015   ENSP00000401431   ENSP00000420489  
     ENSP00000402946   ENSP00000405840   ENSP00000398493   ENSP00000423393   ENSP00000430393  

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    Novus Biologicals PCGF3 Proteins
    Novus Biologicals PCGF3 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for PCGF3 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0031519PcG protein complex IDA--

    PCGF3 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    RNF: RING-type (C3HC4) zinc fingers
    PCGF: Polycomb group ring fingers

    4 InterPro protein domains:
     IPR001841 Znf_RING
     IPR013083 Znf_RING/FYVE/PHD
     IPR017907 Znf_RING_CS
     IPR018957 Znf_C3HC4_RING-type

    Graphical View of Domain Structure for InterPro Entry Q3KNV8

    ProtoNet protein and cluster: Q3KNV8

    UniProtKB/Swiss-Prot: PCGF3_HUMAN, Q3KNV8
    Similarity: Contains 1 RING-type zinc finger


    PCGF3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: PCGF3_HUMAN, Q3KNV8
    Function: Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain
    the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1
    complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A
    'Lys-119', rendering chromatin heritably changed in its expressibility

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
    GO:0008270zinc ion binding IEA--
    GO:0046872metal ion binding ----
         
    PCGF3 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for PCGF3:
     Increased cell death HMECs cel 

         2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Pcgf3):
     hematopoietic system  immune system 

    PCGF3 for phenotypes           About GeneDecksing

    Animal Models:
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for PCGF3 
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    Browse SwitchGear 3'UTR luciferase reporter plasmids
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PCGF3


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for PCGF3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/46 Interacting proteins for PCGF3 (Q3KNV81, 3 ENSP000003547244) via UniProtKB, MINT, STRING, and/or I2D (see all 46)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RNF2Q994961, 3, ENSP000003564804EBI-2339807,EBI-722416 I2D: score=2 STRING: ENSP00000356480
    RING1Q065871, ENSP000003637874EBI-2339807,EBI-752313 STRING: ENSP00000363787
    CBX6O955031, ENSP000003844904EBI-2339807,EBI-3951758 STRING: ENSP00000384490
    CBX7O959311, ENSP000002161334EBI-2339807,EBI-3923843 STRING: ENSP00000216133
    CBX8Q9HC521, ENSP000002693854EBI-2339807,EBI-712912 STRING: ENSP00000269385
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006355regulation of transcription, DNA-dependent IEA--

    PCGF3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for PCGF3

    Search CenterWatch for drugs/clinical trials and news about PCGF3

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for PCGF3 gene: 
    NM_006315.4  

    Unigene Cluster for PCGF3:

    Polycomb group ring finger 3
    Hs.144309  [show with all ESTs]
    Unigene Representative Sequence: NM_006315
    14 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000419774 ENST00000362003(uc003gbe.3 uc010ibh.3 uc003gbh.3)
    ENST00000475288 ENST00000400151 ENST00000482726 ENST00000427463 ENST00000470161(uc011bva.1)
    ENST00000430644(uc003gbc.1) ENST00000484141 ENST00000440452 ENST00000433814
    ENST00000488032 ENST00000505655 ENST00000521023(uc003gbd.1)
    miRNA
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    8/148 QIAGEN miScript miRNA Assays for microRNAs that regulate PCGF3 (see all 148):
    hsa-miR-579 hsa-miR-100* hsa-miR-26a-2* hsa-miR-631 hsa-miR-128 hsa-miR-342-3p hsa-miR-92b hsa-miR-761
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    Browse for Gene Knock-down Tools from EMD Millipore
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    Clone
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PCGF3
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PCGF3

    Additional mRNA sequence: 

    AK057124.1 AK125801.1 AK225892.1 AK300290.1 AL832536.1 BC028026.1 BC050044.1 BC061897.1 
    BC107061.2 BX640894.1 BX648409.1 

    20 DOTS entries:

    DT.449007  DT.100664320  DT.91873562  DT.121264739  DT.75145795  DT.121264743  DT.92061423  DT.95144420 
    DT.121264803  DT.92439663  DT.100730564  DT.40117165  DT.102664  DT.121264719  DT.121264723  DT.121264762 
    DT.121264786  DT.75151154  DT.95219429  DT.95309854 

    24/62 AceView cDNA sequences (see all 62):

    BM672389 AA280702 AI745427 AA335471 AI825812 AV645914 AA904197 AW119197 
    AI338370 AI985777 BX956499 BQ186807 BM352805 BF334282 AV753434 AA325790 
    BQ052208 AK055583 AA335187 AA335956 AA970693 AI669155 BM352490 BM687064 

    GeneLoc Exon Structure

    5/7 Alternative Splicing Database (ASD) splice patterns (SP) for PCGF3 (see all 7)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b · 3c ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14a · 14b ^ 15a · 15b
    SP1:                                -                 -                                                           -               
    SP2:                                -     -           -     -     -                                                               
    SP3:                                                                                                                              
    SP4:                                -     -           -                                                                           
    SP5:                                -     -                                                                                       


    ECgene alternative splicing isoforms for PCGF3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    PCGF3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    PCGF3 Expression
    About this image


    See PCGF3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for PCGF3

    SOURCE GeneReport for Unigene cluster: Hs.144309
        SABiosciences Expression via Pathway-Focused PCR Arrays including PCGF3: 
              Polycomb & Trithorax Complexes in human mouse rat
              Epigenetic Chromatin Remodeling Factors in human mouse rat
              Ubiquitin Ligases in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PCGF3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for PCGF3 gene from 6/14 species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Pcgf31 , 5 polycomb group ring finger 31, 5 88.52(n)1
    97.93(a)1
      5 (53.13 cM)5
    695871  NM_172716.41  NP_766304.21 
     1084612325 
    chicken
    (Gallus gallus)
    Aves PCGF31 polycomb group ring finger 3 82.64(n)
    96.69(a)
      427287  XM_424870.2  XP_424870.2 
    lizard
    (Anolis carolinensis)
    Reptilia PCGF36
    Uncharacterized protein
    95(a)
    1 ↔ 1
    GL343201.1(1265534-1294797)
    African clawed frog
    (Xenopus laevis)
    Amphibia 480431682   -- 76.4(n)    48043168 
    fruit fly
    (Drosophila melanogaster)
    Insecta l(3)73Ah1 lethal (3) 73Ah 64.39(n)
    61.36(a)
      48903  NM_080194.4  NP_524933.1 
    worm
    (Caenorhabditis elegans)
    Secernentea mig-321 Protein MIG-32 44.66(n)
    36.41(a)
      178150  NM_069892.2  NP_502293.2 


    ENSEMBL Gene Tree for PCGF3 (if available)
    TreeFam Gene Tree for PCGF3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for PCGF3 gene
    PCGF52  PCGF22  PCGF62  BMI12  PCGF12  COMMD3-BMI12  
    18/19 SIMAP similar genes for PCGF3 using alignment to 8 protein entries:     PCGF3_HUMAN (see all proteins) (see all similar genes):
    BMI1    PCGF2    PCGF1    PCGF5    TRIM39    RFWD2
    TRIM5    PCGF6    RNF138    BFAR    TRIM60    CHFR
    COMMD3    RNF4    TRIM64C    LONRF1    LNX1    RAG1

    PCGF3 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for PCGF3
    PGOHUM00000248184


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/2160 SNPs in PCGF3 are shown (see all 2160)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 4 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs797395891,2
    C,F--697604(+) TGGCAC/TCCACC 1 -- us2k12Minor allele frequency- T:0.05NA EA 240
    rs1380817691,2
    --697607(+) CACCCA/CCCCAG 1 -- us2k10--------
    rs760578071,2
    C,F--697615(+) CAGGAG/CAGTAG 1 -- us2k13Minor allele frequency- C:0.14WA NA EA 358
    rs1425703331,2
    --697630(+) AAGCCA/TAGGGG 1 -- us2k10--------
    rs1875328701,2
    C--697981(+) CCCTCA/CCTGCC 1 -- us2k10--------
    rs1460116531,2
    --698028(+) CCCTCC/TCCTTC 1 -- us2k10--------
    rs1399166521,2
    C--698178(+) AAGCCA/GCTTCC 1 -- us2k10--------
    rs1491802631,2
    --698210(+) GGCCC-/GGGGCC 1 -- us2k10--------
    rs68371801,2
    C,F,A,H--698292(+) CCACCG/ACCTCT 1 -- us2k124Minor allele frequency- A:0.33NS EA NA WA CSA 2349
    rs1902412461,2
    --698294(+) ACCACC/GTCTCC 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for PCGF3 (699537 - 764428 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/61 variations for PCGF3 (see all 61):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2726686CNV Deletion23290073
    esv2726698CNV Deletion23290073
    esv2726701CNV Deletion23290073
    esv2726702CNV Deletion23290073
    esv1431312CNV Deletion17803354
    esv1002699CNV Deletion20482838
    esv1347923CNV Deletion17803354
    esv2726691CNV Deletion23290073
    esv2741953CNV Deletion23290073
    esv2726688CNV Deletion23290073

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    PCGF3 for disorders           About MalaCards

    PCGF3 for disorders           About GeneDecksing

    Genetic Association Database (GAD): PCGF3

    Export disorders for PCGF3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for PCGF3 gene, integrated from 9 sources (see all 14):
    (articles sorted by number of sources associating them with PCGF3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Genome wide association study for plasma levels of nat ural anticoagulant inhibitors and protein C anticoagulant pathway: the MARTHA pr oject. (PubMed id 22443383)1, 4 Oudot-Mellakh T....Morange P.E. (2012)
    2. Interaction proteomics analysis of polycomb proteins defines distinct PRC1 Complexes in mammalian cells. (PubMed id 21282530)1, 2 Vandamme J.... Angrand P.O. (2011)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Interlaboratory reproducibility of large-scale human p rotein-complex analysis by standardized AP-MS. (PubMed id 23455922)1 Varjosalo M....Superti-Furga G. (2013)
    5. Structure of the polycomb group protein PCGF1 in compl ex with BCOR reveals basis for binding selectivity of PCGF homologs. (PubMed id 23523425)1 Junco S.E....Kim C.A. (2013)
    6. Systematic analysis of dimeric E3-RING interactions re veals increased combinatorial complexity in human ubiquitination networks. (PubMed id 22493164)1 Woodsmith J....Sanderson C.M. (2012)
    7. Quantitative analysis of HSP90-client interactions rev eals principles of substrate recognition. (PubMed id 22939624)1 Taipale M....Lindquist S. (2012)
    8. PCGF homologs, CBX proteins, and RYBP define functiona lly distinct PRC1 family complexes. (PubMed id 22325352)1 Gao Z....Reinberg D. (2012)
    9. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    10. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 10336 HGNC: 10066 AceView: RNF3.1 Ensembl:ENSG00000185619 euGenes: HUgn10336
    ECgene: PCGF3 H-InvDB: PCGF3

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for PCGF3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for PCGF3 gene:
    Search GeneIP for patents involving PCGF3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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