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Aliases for PCDHG@ Gene

Aliases for PCDHG@ Gene

  • Protocadherin Gamma Cluster 2 3
  • Protocadherin Gamma Cluster Extended 3
  • PCDH2 3
  • PCDH4 3
  • PCDHG 3

External Ids for PCDHG@ Gene

Previous GeneCards Identifiers for PCDHG@ Gene

  • GC05U990121
  • GC05P141095
  • GC05P141129
  • GC05P141432
  • GC05P141556
  • GC05P141660
  • GC05P141760

Summaries for PCDHG@ Gene

Entrez Gene Summary for PCDHG@ Gene

  • The protocadherin gamma gene cluster is one of three related clusters tandemly linked on chromosome five. The clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma cluster includes 22 genes divided into 3 subfamilies, all part of the cadherin superfamily. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. In addition, ORNT2 and TAF2F are included in the cluster due to their localization between protocadherin clusters beta and gamma on chromosome five. The protocadherin genes are organized in a tandem array of 22 large, variable region exons followed by a constant region, which contains 3 exons shared by all protocadherin genes in the cluster. Each variable region exon encodes an extracellular domain comprised of 6 cadherin ectodomains and a transmembrane region. The constant region exons encode a common cytoplasmic tail. These neural adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq, Jul 2008]

GeneCards Summary for PCDHG@ Gene

PCDHG@ (Protocadherin Gamma Cluster) is a Gene Cluster.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PCDHG@ Gene

Genomics for PCDHG@ Gene

Regulatory Elements for PCDHG@ Gene

Enhancers for PCDHG@ Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around PCDHG@ on UCSC Golden Path with GeneCards custom track

Promoters for PCDHG@ Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001874442 15 601 BCOR CTCF ZNF223 ZMYM3 ZNF384 BCL11B RAD21 ZNF324 ZNF335 SMC3

Genomic Location for PCDHG@ Gene

141,330,685 bp from pter
141,512,979 bp from pter
182,295 bases
Plus strand

Genomic View for PCDHG@ Gene

Genes around PCDHG@ on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
PCDHG@ Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PCDHG@ Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PCDHG@ Gene

Proteins for PCDHG@ Gene

Post-translational modifications for PCDHG@ Gene

No Post-translational modifications

No data available for DME Specific Peptides for PCDHG@ Gene

Domains & Families for PCDHG@ Gene

Gene Families for PCDHG@ Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with PCDHG@: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for PCDHG@ Gene

Function for PCDHG@ Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for PCDHG@ Gene

Localization for PCDHG@ Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for PCDHG@ Gene

Pathways & Interactions for PCDHG@ Gene

SuperPathways for PCDHG@ Gene

No Data Available

Interacting Proteins for PCDHG@ Gene

Gene Ontology (GO) - Biological Process for PCDHG@ Gene


No data available for Pathways by source and SIGNOR curated interactions for PCDHG@ Gene

Transcripts for PCDHG@ Gene

Alternative Splicing Database (ASD) splice patterns (SP) for PCDHG@ Gene

No ASD Table

Relevant External Links for PCDHG@ Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

No data available for mRNA/cDNA for PCDHG@ Gene

Expression for PCDHG@ Gene

NURSA nuclear receptor signaling pathways regulating expression of PCDHG@ Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for PCDHG@ Gene

Orthologs for PCDHG@ Gene

No data available for Orthologs and Evolution for PCDHG@ Gene

Paralogs for PCDHG@ Gene

No data available for Paralogs for PCDHG@ Gene

Variants for PCDHG@ Gene

Relevant External Links for PCDHG@ Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for PCDHG@ Gene

Disorders for PCDHG@ Gene

No disorders were found for PCDHG@ Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for PCDHG@ Gene

Publications for PCDHG@ Gene

  1. Frequent long-range epigenetic silencing of protocadherin gene clusters on chromosome 5q31 in Wilms' tumor. (PMID: 19956686) Dallosso A.R. … Malik K. (PLoS Genet. 2009) 3 22 64
  2. A striking organization of a large family of human neural cadherin- like cell adhesion genes. (PMID: 10380929) Wu Q. … Maniatis T. (Cell 1999) 2 3 64
  3. Control of CNS synapse development by {gamma}-protocadherin-mediated astrocyte-neuron contact. (PMID: 19776259) Garrett A.M. … Weiner J.A. (J. Neurosci. 2009) 22 64
  4. Gamma protocadherin expression in the embryonic chick nervous system. (PMID: 17200686) Cronin K.D. … Capehart A.A. (Int. J. Biol. Sci. 2007) 22 64
  5. Differential expression of individual gamma-protocadherins during mouse brain development. (PMID: 15964765) Frank M. … Kemler R. (Mol. Cell. Neurosci. 2005) 22 64

Products for PCDHG@ Gene

Sources for PCDHG@ Gene

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