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Aliases for PCDHB@ Gene

Aliases for PCDHB@ Gene

  • Protocadherin Beta Cluster 2 3
  • PCDH3 3

External Ids for PCDHB@ Gene

Previous GeneCards Identifiers for PCDHB@ Gene

  • GC05U990122
  • GC05P140431
  • GC05P140442
  • GC05P140453

Summaries for PCDHB@ Gene

Entrez Gene Summary for PCDHB@ Gene

  • The protocadherin beta cluster is one of three related gene clusters tandemly linked on chromosome five. The protocadherin genes have an immunoglobulin-like genomic organization, suggesting that a novel mechanism may be involved in their regulation and expression. The beta cluster contains 16 genes and 3 pseudogenes. Each gene product contains 6 extracellular cadherin domains and a cytoplasmic tail that diverges from other cadherin superfamily members. Unlike the alpha and gamma clusters, the beta cluster has a variable region but lacks a constant region. Without this downstream region of shared exons, each transcript encodes a unique cytoplasmic tail. The specific functions of these one-exon gene products are unknown; however, they are thought to play a critical role in the establishment and function of specific cell-cell neural connections. [provided by RefSeq, Jul 2008]

GeneCards Summary for PCDHB@ Gene

PCDHB@ (Protocadherin Beta Cluster) is a Gene Cluster.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PCDHB@ Gene

Genomics for PCDHB@ Gene

Genomic Location for PCDHB@ Gene

141,051,394 bp from pter
141,248,234 bp from pter
196,841 bases
Plus strand

Genomic View for PCDHB@ Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for PCDHB@ Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PCDHB@ Gene

No data available for Regulatory Elements for PCDHB@ Gene

Proteins for PCDHB@ Gene

Post-translational modifications for PCDHB@ Gene

No Post-translational modifications

No data available for DME Specific Peptides for PCDHB@ Gene

Domains for PCDHB@ Gene

Gene Families for PCDHB@ Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with PCDHB@: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for PCDHB@ Gene

Function for PCDHB@ Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for PCDHB@ Gene

Localization for PCDHB@ Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for PCDHB@ Gene

Pathways for PCDHB@ Gene

SuperPathways for PCDHB@ Gene

No Data Available

Interacting Proteins for PCDHB@ Gene

Gene Ontology (GO) - Biological Process for PCDHB@ Gene


No data available for Pathways by source for PCDHB@ Gene

Transcripts for PCDHB@ Gene

Alternative Splicing Database (ASD) splice patterns (SP) for PCDHB@ Gene

No ASD Table

Relevant External Links for PCDHB@ Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

No data available for mRNA/cDNA for PCDHB@ Gene

Expression for PCDHB@ Gene

No Expression Related Data Available

Primer Products

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for PCDHB@ Gene

Orthologs for PCDHB@ Gene

No data available for Orthologs and Evolution for PCDHB@ Gene

Paralogs for PCDHB@ Gene

No data available for Paralogs for PCDHB@ Gene

Variants for PCDHB@ Gene

Relevant External Links for PCDHB@ Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for PCDHB@ Gene

Disorders for PCDHB@ Gene

No disorders were found for PCDHB@ Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for PCDHB@ Gene

Publications for PCDHB@ Gene

  1. A striking organization of a large family of human neural cadherin- like cell adhesion genes. (PMID: 10380929) Wu Q. … Maniatis T. (Cell 1999) 2 3
  2. Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes. (PMID: 10716726) Wu Q. … Maniatis T. (Proc. Natl. Acad. Sci. U.S.A. 2000) 3
  3. Comparative DNA sequence analysis of mouse and human protocadherin gene clusters. (PMID: 11230163) Wu Q. … Maniatis T. (Genome Res. 2001) 3
  4. The human and murine protocadherin-beta one-exon gene families show high evolutionary conservation, despite the difference in gene number. (PMID: 11322959) Vanhalst K. … van Roy F. (FEBS Lett. 2001) 3
  5. Frequent long-range epigenetic silencing of protocadherin gene clusters on chromosome 5q31 in Wilms' tumor. (PMID: 19956686) Dallosso A.R. … Malik K. (PLoS Genet. 2009) 3

Products for PCDHB@ Gene

Sources for PCDHB@ Gene

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