Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

PCDHB1 Gene

protein-coding   GIFtS: 44
GCID: GC05P140433

Protocadherin Beta 1

  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Protocadherin Beta 11 2
PCDH-beta-12 3
PCDH-BETA12
Protocadherin Beta-12

External Ids:    HGNC: 86801   Entrez Gene: 299302   Ensembl: ENSG000001718157   OMIM: 6063275   UniProtKB: Q9Y5F33   

Export aliases for PCDHB1 gene to outside databases

Previous GC identifers: GC05P140247 GC05P141013 GC05P140414 GC05P140459 GC05P140411 GC05P135575 GC05P140432


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for PCDHB1 Gene:
This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked
on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and
T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6
extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The
extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the
alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common
3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins.
Their specific functions are unknown but they most likely play a critical role in the establishment and function
of specific cell-cell neural connections. (provided by RefSeq, Jul 2008)

GeneCards Summary for PCDHB1 Gene: 
PCDHB1 (protocadherin beta 1) is a protein-coding gene. Diseases associated with PCDHB1 include neuronitis. GO annotations related to this gene include calcium ion binding. An important paralog of this gene is PCDHAC1.

UniProtKB/Swiss-Prot: PCDB1_HUMAN, Q9Y5F3
Function: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance
of specific neuronal connections in the brain




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000005.9  NC_018916.2  NT_029289.11  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the PCDHB1 gene promoter:
         Nkx3-1   ER-alpha   Nkx3-1 v4   p53   NRSF form 1   Nkx3-1 v1   NRSF form 2   AREB6   Nkx3-1 v2   Nkx3-1 v3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidPCDHB1 promoter sequence
   Search SABiosciences Chromatin IP Primers for PCDHB1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PCDHB1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q31   Ensembl cytogenetic band:  5q31.3   HGNC cytogenetic band: 5q31

PCDHB1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PCDHB1 gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05P140433:  view genomic region     (about GC identifiers)

Start:
140,430,979 bp from pter      End:
140,433,512 bp from pter
Size:
2,534 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: PCDB1_HUMAN, Q9Y5F3 (See protein sequence)
Recommended Name: Protocadherin beta-1 precursor  
Size: 818 amino acids; 90491 Da
Subcellular location: Cell membrane; Single-pass type I membrane protein (By similarity)
Secondary accessions: Q2M257

Explore the universe of human proteins at neXtProt for PCDHB1: NX_Q9Y5F3

Explore proteomics data for PCDHB1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9Y5F3

  • PCDHB1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    PCDHB1 Protein Expression
    REFSEQ proteins: NP_037472.2  
    ENSEMBL proteins: 
     ENSP00000307234  

    Human Recombinant Protein Products for PCDHB1: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for PCDHB1
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for PCDHB1
    GenScript Custom Purified and Recombinant Proteins Services for PCDHB1
    Novus Biologicals PCDHB1 Protein
    Novus Biologicals PCDHB1 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane IEA--
    GO:0016020membrane ----
    GO:0016021integral to membrane IEA--

    PCDHB1 for ontologies           About GeneDecksing



    PCDHB1 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for PCDHB1
    GenScript Custom Superior Antibodies Services for PCDHB1
    Novus Biologicals PCDHB1 Antibodies
    Abcam antibodies for PCDHB1
    Browse Antibodies at Cloud-Clone Corp. 
    Search ThermoFisher Antibodies for PCDHB1
    LSBio Antibodies in human, mouse, rat for PCDHB1 

    Assay Products for PCDHB1: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for PCDHB1
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for PCDHB1
    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs at Cloud-Clone Corp. 
    Browse CLIAs at Cloud-Clone Corp.


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    PCDHC: Cadherins / Protocadherins : Clustered

    4 InterPro protein domains:
     IPR015919 Cadherin-like
     IPR013164 Cadherin_N
     IPR020894 Cadherin_CS
     IPR002126 Cadherin

    Graphical View of Domain Structure for InterPro Entry Q9Y5F3

    ProtoNet protein and cluster: Q9Y5F3

    1 Blocks protein domain: IPB002126 Cadherin

    UniProtKB/Swiss-Prot: PCDB1_HUMAN, Q9Y5F3
    Similarity: Contains 6 cadherin domains


    PCDHB1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: PCDB1_HUMAN, Q9Y5F3
    Function: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance
    of specific neuronal connections in the brain

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005509calcium ion binding IEA--
         
    PCDHB1 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for PCDHB1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for PCDHB1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for PCDHB1 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for PCDHB1 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat PCDHB1
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate PCDHB1
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for PCDHB1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat PCDHB1

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for PCDHB1
    Sirion Biotech Customized adenovirus for overexpression of PCDHB1

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for PCDHB1 (see all 6)
    OriGene ORF clones in mouse, rat for PCDHB1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: PCDHB1 (NM_013340)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for PCDHB1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PCDHB1
    Sirion Biotech Customized lentivirus for stable overexpression of PCDHB1 
                         Customized lentivirus expression plasmids for stable overexpression of PCDHB1 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for PCDHB1
    Search LifeMap BioReagents cell lines for PCDHB1
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PCDHB1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for PCDHB1

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007156homophilic cell adhesion IEA--

    PCDHB1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for PCDHB1 (PCDB1)

    1 HMDB Compound for PCDHB1    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--

    Search CenterWatch for drugs/clinical trials and news about PCDHB1 / PCDB1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for PCDHB1 gene: 
    NM_013340.3  

    Unigene Cluster for PCDHB1:

    Protocadherin beta 1
    Hs.278950  [show with all ESTs]
    Unigene Representative Sequence: BC112096
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000306549(uc003lik.1)
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat PCDHB1
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate PCDHB1
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for PCDHB1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat PCDHB1
    Clone
    Products:
         
    OriGene clones in human, mouse for PCDHB1 (see all 6)
    OriGene ORF clones in mouse, rat for PCDHB1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: PCDHB1 (NM_013340)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for PCDHB1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PCDHB1
    Sirion Biotech Customized lentivirus for stable overexpression of PCDHB1 
                         Customized lentivirus expression plasmids for stable overexpression of PCDHB1 
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for PCDHB1
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat PCDHB1
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PCDHB1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PCDHB1

    Additional mRNA sequence: 

    AF152488.1 BC112096.1 BC112098.1 

    1 DOTS entry:

    DT.91669151 

    5 AceView cDNA sequences:

    AA447615 BX097466 AA448271 AA448114 BG193185 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    PCDHB1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ACCAGGTATC
    PCDHB1 Expression
    About this image


    See PCDHB1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for PCDHB1

    SOURCE GeneReport for Unigene cluster: Hs.278950
        SABiosciences Custom PCR Arrays for PCDHB1
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for PCDHB1
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat PCDHB1
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PCDHB1
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PCDHB1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PCDHB1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for PCDHB1 gene from 3/10 species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Pcdhb11 , 5 protocadherin beta 11, 5 85.04(n)1
    88.02(a)1
      18 (19.46 cM)5
    938721  NM_053126.11  NP_444356.11 
     372649985 
    chicken
    (Gallus gallus)
    Aves --
    GGA.522176
    (see all 3)
    Uncharacterized protein
    (see all 3)
    44(a)
    43(a)
    (see all 3)
    possible ortholog
    possible ortholog
    (see all 3)
    13(75118-78451)
    13(135780-139265)
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    (see all 16)
    Protocadherin beta 7; Uncharacterized protein
    (see all 16)
    50(a)
    47(a)
    (see all 16)
    possible ortholog
    possible ortholog
    (see all 16)
    AAWZ02039895(5757-7706)
    4(77018361-77020784)


    ENSEMBL Gene Tree for PCDHB1 (if available)
    TreeFam Gene Tree for PCDHB1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for PCDHB1 gene
    PCDHAC12  PCDHB162  PCDHB22  PCDHAC22  PCDHB72  PCDHB152  PCDHGA102  PCDHGB22  
    PCDHGA122  PCDHGA92  PCDHGA82  PCDHGC32  PCDHGA52  PCDHA82  PCDHB52  PCDHB132  
    PCDHGA42  PCDHGA72  PCDHB42  PCDHB112  PCDHA22  ENSG000002556222  PCDHB142  PCDHB122  
    PCDHB82  PCDHGB12  PCDHGB42  PCDHA52  PCDHGA22  PCDHGA62  PCDHB32  PCDHGA112  
    PCDHB62  PCDHGC42  PCDHGC52  PCDHGA12  PCDHB102  PCDHGB72  PCDHGA32  
    18/64 SIMAP similar genes for PCDHB1 using alignment to 1 protein entry:     PCDB1_HUMAN(see all similar genes):
    PCDHB13    PCDHB16    PCDHB17    PCDHB18    PCDHB3    DKFZp586I1919
    PCDHB8    PCDHB14    PCDHB2    PCDHB10    PCDHB12    PCDHB15
    PCDHB4    PCDHB5    PCDHB6    PCDHB7    PCDHB9    PCDHB11

    PCDHB1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/153 SNPs in PCDHB1 are shown (see all 153)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 5 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs349078001,2
    C,F--140429046(+) TCTACA/GTAAGA 1 -- us2k18Minor allele frequency- G:0.10NA WA CSA EA 367
    rs1860494871,2
    --140429114(+) CACTCC/TGCTTC 1 -- us2k10--------
    rs1906257211,2
    --140429377(+) TAAAAA/TATGAG 1 -- us2k10--------
    rs1840673161,2
    --140429561(+) ATTCAC/TTAATT 1 -- us2k10--------
    rs1863409771,2
    --140429660(+) AGTGGC/TCATAA 1 -- us2k10--------
    rs1906938481,2
    C--140429815(+) ACTTCA/GGGCCT 1 -- us2k10--------
    rs1829781001,2
    --140429866(+) GTGGGA/TGAGAA 1 -- us2k10--------
    rs37761051,2
    C,F,H--140429943(-) TTTGTT/CGAGTT 1 -- us2k122Minor allele frequency- C:0.26NA NS EA WA CSA 2477
    rs1872799281,2
    --140430061(+) TATTAC/TCTGGG 1 -- us2k10--------
    rs1511397911,2
    --140430165(+) TGACAC/TAACCT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for PCDHB1 (140430979 - 140433512 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for PCDHB1:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv428127CNV Loss18775914
    nsv818387CNV Gain17921354
    dgv1857e1CNV Complex17122850

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing PCDHB1
    DNA2.0 Custom Variant and Variant Library Synthesis for PCDHB1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 606327    OMIM disorders: --

    2 diseases for PCDHB1:    About MalaCards
    neuronitis    


    PCDHB1 for disorders           About GeneDecksing


    Export disorders for PCDHB1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for PCDHB1 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with PCDHB1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A striking organization of a large family of human neural cadherin- like cell adhesion genes. (PubMed id 10380929)1, 2, 3 Wu Q. and Maniatis T. (1999)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    4. Comparative DNA sequence analysis of mouse and human protocadherin gene clusters. (PubMed id 11230163)1 Wu Q.... Maniatis T. (2001)
    5. The human and murine protocadherin-beta one-exon gene families show high evolutionary conservation, despite the difference in gene number. (PubMed id 11322959)1 Vanhalst K.... van Roy F. (2001)
    6. Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members. (PubMed id 10835267)1 Nollet F....van Roy F. (2000)
    7. Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes. (PubMed id 10716726)1 Wu Q. and Maniatis T. (2000)
    8. Cadherin superfamily genes: functions, genomic organization, and neurologic diversity. (PubMed id 10817752)1 Yagi T. and Takeichi M. (2000)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 29930 HGNC: 8680 AceView: PCDHB1.1 Ensembl:ENSG00000171815 euGenes: HUgn29930
    ECgene: PCDHB1 H-InvDB: PCDHB1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for PCDHB1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for PCDHB1 gene:
    Search GeneIP for patents involving PCDHB1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for PCDHB1  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for PCDHB1  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for PCDHB1  
     OriGene qSTAR qPCR primer pairs in human, mouse for PCDHB1   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for PCDHB1   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for PCDHB1   OriGene Custom Protein Services for PCDHB1  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat PCDHB1
     QIAGEN SeqTarget long-range PCR primers for resequencing PCDHB1
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PCDHB1
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat PCDHB1
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PCDHB1
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PCDHB1
     GenScript Custom Purified and Recombinant Proteins Services for PCDHB1 GenScript cDNA clones with any tag delivered in your preferred vector for PCDHB1
     GenScript Custom Assay Services for PCDHB1 GenScript Custom Superior Antibodies Services for PCDHB1
     GenScript Custom overexpressing Cell Line Services for PCDHB1 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in PCDHB1 promoter
     Search Chromatin IP Primers for PCDHB1
     RT2 qPCR Primer Assay in human, mouse, rat PCDHB1
     Search GNC Networks for PCDHB1
     SABiosciences Custom PCR Arrays for PCDHB1
     Search Tocris compounds for PCDHB1 (PCDB1)
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     PCDHB1 antibodies
     PCDHB1 proteins
     PCDHB1 lysates
     Antibodies for PCDHB1
     See all of Abcam's Antibodies, Kits and Proteins for PCDHB1
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Browse Proteins at Cloud-Clone Corp.
     Browse Antibodies at Cloud-Clone Corp.
     Browse ELISAs at Cloud-Clone Corp.
     Browse CLIAs at Cloud-Clone Corp.
     Search LifeMap BioReagents cell lines for PCDHB1
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PCDHB1
     Browse SwitchGear 3'UTR luciferase reporter plasmids for PCDHB1
     SwitchGear Promoter luciferase reporter plasmids for PCDHB1
     Search ThermoFisher Antibodies for PCDHB1
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PCDHB1
     inGenious Targeting Laboratory - Custom generated mouse model solutions for PCDHB1
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for PCDHB1
    Customized:
     lentivirus for stable overexpression of PCDHB1
     lentivirus expression plasmids for stable overexpression of PCDHB1
     adenovirus for overexpression of PCDHB1
     LSBio Antibodies in human, mouse, rat for PCDHB1
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      PCDHB1 gene at Home site.
    hostname: 356977-web1.xennexinc.com index build: 106 solr: 1.4