Aliases for PCDH11X Gene
External Ids for PCDH11X Gene
Previous HGNC Symbols for PCDH11X Gene
Previous GeneCards Identifiers for PCDH11X Gene
This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The encoded protein consists of an extracellular domain containing 7 cadherin repeats, a transmembrane domain and a cytoplasmic tail that differs from those of the classical cadherins. The gene is located in a major X/Y block of homology and its Y homolog, despite divergence leading to coding region changes, is the most closely related cadherin family member. The protein is thought to play a fundamental role in cell-cell recognition essential for the segmental development and function of the central nervous system. Disruption of this gene may be associated with developmental dyslexia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]
GeneCards Summary for PCDH11X Gene
PCDH11X (Protocadherin 11 X-Linked) is a Protein Coding gene. Diseases associated with PCDH11X include Dyslexia and Spherocytosis, Hereditary, Type 5. GO annotations related to this gene include calcium ion binding. An important paralog of this gene is PCDH11Y.
UniProtKB/Swiss-Prot for PCDH11X Gene
Potential calcium-dependent cell-adhesion protein.