Aliases for PCCB Gene
External Ids for PCCB Gene
The protein encoded by this gene is a subunit of the propionyl-CoA carboxylase (PCC) enzyme, which is involved in the catabolism of propionyl-CoA. PCC is a mitochondrial enzyme that probably acts as a dodecamer of six alpha subunits and six beta subunits. This gene encodes the beta subunit of PCC. Defects in this gene are a cause of propionic acidemia type II (PA-2). Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2010]
GeneCards Summary for PCCB Gene
PCCB (Propionyl CoA Carboxylase, Beta Polypeptide) is a Protein Coding gene. Diseases associated with PCCB include pccb-related propionic acidemia and biotinidase deficiency. Among its related pathways are Disease and Metabolism. GO annotations related to this gene include propionyl-CoA carboxylase activity. An important paralog of this gene is MCCC2.