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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

PBXIP1 Gene

protein-coding GIFtS: 47
GCID: GC01M154916

pre-B-cell leukemia homeobox interacting protein 1

(Previous name: pre-B-cell leukemia transcription factor interacting protein...)

Explore 3 diseases affiliated with
PBXIP1 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Pre-B-Cell Leukemia Homeobox Interacting Protein 1¹ ²
HPIP¹ ² ³
Pre-B-Cell Leukemia Transcription Factor Interacting Protein 1¹ ²
Hematopoietic PBX-Interacting Protein² ³
Pre-B-Cell Leukemia Transcription Factor-Interacting Protein 1²

External Ids:	HGNC: 21199¹	Entrez Gene: 57326²	Ensembl: ENSG00000163346⁷	UniProtKB: Q96AQ6³

Export aliases for PBXIP1 gene to outside databases

Previous GC identifers: GC01M151691 GC01M152133 GC01M151729 GC01M153183 GC01M126278

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: PBIP1_HUMAN, Q96AQ6

Function: Regulator of pre-B-cell leukemia transcription factors (BPXs) function. Inhibits the binding of PBX1-HOX

complex to DNA and blocks the transcriptional activity of E2A-PBX1. Tethers estrogen receptor-alpha (ESR1) to

microtubules and allows them to influence estrogen receptors-alpha signaling

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000001.10 NC_018912.1 NT_004487.19

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the PBXIP1 gene promoter:
c-Rel p53 AP-1 HOXA5 STAT3 c-Myb Pax-4a E47
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: PBXIP1 promoter sequence

Search SABiosciences Chromatin IP Primers for PBXIP1

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PBXIP1

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q21.3 Ensembl cytogenetic band: 1q21.3 HGNC cytogenetic band: 1q22

PBXIP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PBXIP1 gene location

GeneLoc information about chromosome 1 GeneLoc Exon Structure

GeneLoc location for GC01M154916: view genomic region (about GC identifiers)

Start:	154,916,552 bp from pter	End:	154,928,599 bp from pter
Size:	12,048 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: PBIP1_HUMAN, Q96AQ6 (See protein sequence)

Recommended Name: Pre-B-cell leukemia transcription factor-interacting protein 1

Size: 731 amino acids; 80643 Da

Subunit: Interacts with ESR1, PBX1, PBX2 and PBX3

Subcellular location: Cytoplasm, cytoskeleton. Nucleus. Note=Shuttles between the nucleus and the cytosol. Mainly

localized in the cytoplasm, associated with microtubules. Detected in small amounts in the nucleus

Secondary accessions: Q5T174 Q5T176 Q9H8X6 Q9HA02 Q9HD85

Alternative splicing: 3 isoforms: Q96AQ6-1 Q96AQ6-2 Q96AQ6-3

Explore the universe of human proteins at neXtProt for PBXIP1: NX_Q96AQ6

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q96AQ6

PBXIP1 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_065385.2

ENSEMBL proteins:

ENSP00000357450 ENSP00000357448 ENSP00000295523 ENSP00000357445 ENSP00000432543

ENSP00000440142 ENSP00000438584

Human Recombinant Protein Products:

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	Novus Biologicals PBXIP1 Protein Novus Biologicals PBXIP1 Lysates
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for PBXIP1

Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	NAS	10825160
GO:0005737	cytoplasm	IDA	--
GO:0005829	cytosol	NAS	10825160
GO:0005874	microtubule	IEA	--
GO:0043231	intracellular membrane-bounded organelle	IDA	--

PBXIP1 for ontologies About GeneDecksing

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	Uscn ELISAs and CLIAs for PBXIP1

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

PBXIP1 for domains About GeneDecksing

1 InterPro domain/family:

IPR024139 TF-int_PBXIP1

Graphical View of Domain Structure for InterPro Entry Q96AQ6

ProtoNet protein and cluster: Q96AQ6

UniProtKB/Swiss-Prot: PBIP1_HUMAN, Q96AQ6

Domain: The C-terminal domain (AA 443-731) contains a nuclear export signal

Domain: Association to the cytoskeleton through a N-terminal leucine rich-domain (AA 190-218)

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: PBIP1_HUMAN, Q96AQ6

Function: Regulator of pre-B-cell leukemia transcription factors (BPXs) function. Inhibits the binding of PBX1-HOX

complex to DNA and blocks the transcriptional activity of E2A-PBX1. Tethers estrogen receptor-alpha (ESR1) to

microtubules and allows them to influence estrogen receptors-alpha signaling

miRNA Products:		OriGene 3'-UTR Clone: PBXIP1 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat PBXIP1
		8/10 QIAGEN miScript miRNA Assays for microRNAs that regulate PBXIP1 (see all 10):
		hsa-miR-153 hsa-miR-3142 hsa-miR-152 hsa-miR-3679-5p hsa-miR-2115 hsa-miR-148b hsa-miR-129-3p hsa-miR-129*

		SwitchGear 3'UTR luciferase reporter plasmid: PBXIP1 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for PBXIP1 (see all 7) OriGene shRNA RFP: PBXIP1 OriGene siRNA: PBXIP1
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Gene Editing
Products:

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		DNA2.0 Custom Codon Optimized Gene Synthesis Service for PBXIP1
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PBXIP1

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for PBXIP1
		Search LifeMap BioReagents cell lines for PBXIP1

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PBXIP1

Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003677	DNA binding	--	--
GO:0003714	transcription corepressor activity	NAS	10825160
GO:0005515	protein binding	IPI	19060904

PBXIP1 for ontologies About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for PBXIP1

STRING Interaction Network Preview (showing 5 interactants - click image to see 18)

5/23 Interacting proteins for PBXIP1 (Q96AQ6^{1, 2, 3} ENSP00000357448⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 23)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
CCDC53	Q9Y3C0¹^,²^,³, ENSP00000240079⁴	EBI-1210745,EBI-712969 MINT-66653 I2D: score=5 STRING: ENSP00000240079
CCDC85B	Q15834²^,³, ENSP00000311695⁴	MINT-66112 I2D: score=5 STRING: ENSP00000311695
DPPA2	Q7Z7J5²^,³	MINT-66870 I2D: score=4
TSNAX	Q99598³, ENSP00000355599⁴	I2D: score=4 STRING: ENSP00000355599
BRPF1	P55201³, ENSP00000373340⁴	I2D: score=1 STRING: ENSP00000373340

About this table

Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0007275	multicellular organismal development	NAS	10825160
GO:0030154	cell differentiation	NAS	10825160
GO:0045892	negative regulation of transcription, DNA-dependent	NAS	10825160

PBXIP1 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for PBXIP1
Search CenterWatch for drugs/clinical trials and news about PBXIP1 / PBIP1

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for PBXIP1 gene:

NM_020524.2

Unigene Cluster for PBXIP1:

Pre-B-cell leukemia homeobox interacting protein 1

Hs.505806 [show with all ESTs]

Unigene Representative Sequence: NM_020524

9 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000368465(uc001ffs.3 uc010pep.2) ENST00000368463(uc001ffr.3)

ENST00000351146 ENST00000368460 ENST00000498553 ENST00000490230 ENST00000493133(uc009woy.1)

ENST00000539880 ENST00000542459

miRNA Products:		OriGene 3'-UTR Clone: PBXIP1 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat PBXIP1
		8/10 QIAGEN miScript miRNA Assays for microRNAs that regulate PBXIP1 (see all 10):
		hsa-miR-153 hsa-miR-3142 hsa-miR-152 hsa-miR-3679-5p hsa-miR-2115 hsa-miR-148b hsa-miR-129-3p hsa-miR-129*

		SwitchGear 3'UTR luciferase reporter plasmid: PBXIP1 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for PBXIP1 (see all 7) OriGene shRNA RFP: PBXIP1 OriGene siRNA: PBXIP1
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat PBXIP1

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PBXIP1 (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PBXIP1 OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: PBXIP1 (NM_020524)
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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PBXIP1

Additional cDNA sequence:

AF221521.1 AK022497.1 AK023219.1 AK300544.1 AK300987.1 AK303413.1 AK303863.1 AK310388.1

AK310712.1 AK315551.1 BC016852.1 BC127909.1 BC127910.1 U00952.1

24/29 DOTS entries (see all 29):

DT.95223072 DT.454262 DT.121413992 DT.100798438 DT.121414045 DT.95223074 DT.100688115 DT.100798439

DT.100798445 DT.100798442 DT.121413720 DT.121413995 DT.100040569 DT.100798440 DT.91750144 DT.95223058

DT.121413844 DT.100042761 DT.100798446 DT.100684934 DT.100689095 DT.100798441 DT.121414009 DT.121414023

24/318 AceView cDNA sequences (see all 318):

CA396235 BM820493 AA679875 T33662 BQ549344 BU733544 BU072974 CK820424

BU783591 BM826888 AW026195 BQ635927 BQ478398 AA082499 AI784101 AA363257

BQ270417 AA378711 NM_020524 CA454935 AI348291 AA723588 BQ267484 BM710511

GeneLoc Exon Structure

5/26 Alternative Splicing Database (ASD) splice patterns (SP) for PBXIP1 (see all 26) About this scheme

ExUns:	1a	·	1b	·	1c	^	2a	·	2b	·	2c	·	2d	^	3a	·	3b	·	3c	·	3d	·	3e	^	4	^	5a	·	5b	·	5c	·	5d	^	6a	·	6b	·	6c	·	6d	^	7a	·	7b	·	7c	·	7d	^	8a	·
SP1:							-		-		-		-		-								-		-		-		-						-		-														-
SP2:							-		-		-		-		-								-		-		-		-						-		-														-
SP3:							-		-		-		-		-		-		-		-		-		-		-		-						-		-														-
SP4:							-		-		-		-		-								-		-		-		-						-		-														-
SP5:							-		-		-		-		-								-		-		-		-						-		-										-		-		-

ExUns:	8b	·	8c	·	8d	·	8e	^	9a	·	9b	·	9c	·	9d	^	10	^	11a	·	11b	^	12a	·	12b	·	12c	^	13	^	14	^	15
SP1:																											-
SP2:																											-
SP3:																											-
SP4:											-		-		-
SP5:	-		-		-		-		-		-		-		-		-		-

ECgene alternative splicing isoforms for PBXIP1

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

PBXIP1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTGACCGGTG

About this image

PBXIP1 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 1 LifeMap Cell

Name

Category

Mature follicles (In-vitro growth and ...)

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See PBXIP1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for PBXIP1

SOURCE GeneReport for Unigene cluster: Hs.505806

UniProtKB/Swiss-Prot: PBIP1_HUMAN, Q96AQ6

Tissue specificity: Expressed in early hematopoietic precursors

SABiosciences Custom PCR Arrays for PBXIP1

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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PBXIP1

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PBXIP1

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for PBXIP1 gene from 2/8 species (see all 8) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	LOC100857958¹	uncharacterized LOC100857958	51.63(n) 39.43(a)		100857958 XM_003642662.1 XP_003642710.1
zebrafish (Danio rerio)	Actinopterygii	pbxip1a⁶ pbxip1b⁶	pre-B-cell leukemia homeobox interacting protein 1... pre-B-cell leukemia homeobox interacting protein 1...	19(a) 18(a)	1 ↔ many 1 ↔ many	19(8172390-8193009) 16(24930468-24955822)

ENSEMBL Gene Tree for PBXIP1 (if available)
TreeFam Gene Tree for PBXIP1 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for PBXIP1 gene

CCPG1²

PBXIP1 for paralogs About GeneDecksing

1 Pseudogenes.org Pseudogene for PBXIP1
PGOHUM00000244278

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 1 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs2102423^1,2	C,F,O,A,H,	--	154916068(+)	`AATGAG/ACTAAT`	1	--	int¹		19		NS EA NA WA CSA	1090
rs2335409^1,2	C,F,O,A,H,	--	154916106(+)	`TATTCA/GCTTGC`	1	--	int¹		15		NS EA NA CSA WA	926
rs183727475^1,2		--	154916250(+)	`ATTGCC/TGAAGG`	1	--	int¹		0	--	--	--	--
rs57077887^1,2	F,	--	154916293(+)	`GAGAAT/CAGCCA`	1	--	int¹		1		WA	118
rs61201736^1,2	F,	--	154916310(+)	`GTCTGG/CTCATC`	1	--	int¹		1		EA	120
rs190798318^1,2		--	154916380(+)	`GGGGAC/TAGTGA`	1	--	int¹		0	--	--	--	--
rs139559203^1,2		--	154916418(+)	`AAATGA/GAGCCA`	1	--	int¹		0	--	--	--	--
rs41264245^1,2	F,	--	154916465(+)	`CAGAAG/ACTCTT`	1	--	int¹		1		NA	120
rs41264247^1,2		--	154916489(+)	`GGTTCC/TTTTCC`	1	--	int¹		0	--	--	--	--
rs186980914^1,2		--	154916535(+)	`TTTGAA/GTGCCC`	1	--	int¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for PBXIP1 (154916552 - 154928599 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for PBXIP1: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PBXIP1

DNA2.0 Custom Variant and Variant Library Synthesis for PBXIP1

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

PBXIP1 for disorders About GeneDecksing

3 diseases for PBXIP1: About MalaCards

t-cell leukemia leukemia ataxia

Export disorders for PBXIP1 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for PBXIP1 gene, integrated from 9 sources (see all 24):
(articles sorted by number of sources associating them with PBXIP1)

Utopia: connect your pdf to the dynamic
world of online information

Functional cloning and characterization of a novel nonhomeodomain protein that inhibits the binding of PBX1-HOX complexes to DNA. (PubMed id 10825160)^{1, 2, 3} Abramovich C.... Humphries R.K. (2000)
Functional characterization of multiple domains involved in the subcellular localization of the hematopoietic Pbx interacting protein (HPIP). (PubMed id 12360403)^{1, 2, 9} Abramovich C.... Humphries R.K. (2002)
An inherent role of microtubule network in the action of nuclear receptor. (PubMed id 17043237)^{1, 2} Manavathi B.... Kumar R. (2006)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Expression of (cac)n/(gtg)n simple repetitive sequences in mRNA of human lymphocytes. (PubMed id 7505766)^{1, 3} Epplen C. and Epplen J.T. (1994)
Functional regulation of pre-B-cell leukemia homeobox interacting protein 1 (PBXIP1/HPIP) in erythroid differentiation. (PubMed id 22187427)¹ Manavathi B....Humphries R.K. (2012)
Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)¹ Kim W....Gygi S.P. (2011)
System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)² Rigbolt K.T....Blagoev B. (2011)
Ubiquitin ligase substrate identification through qua ntitative proteomics at both the protein and peptide levels. (PubMed id 21987572)¹ Lee K.A....Doedens J.R. (2011)
Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)² Olsen J.V....Mann M. (2010)

(in PubMed, OMIM, and NCBI Bookshelf)
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 57326	HGNC: 21199	AceView: PBXIP1	Ensembl:ENSG00000163346	euGenes: HUgn57326
ECgene: PBXIP1	H-InvDB: PBXIP1

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for PBXIP1	Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for PBXIP1	Genetics and Cytogenetics in Oncology and Haematology

Intellectual Property for PBXIP1 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for PBXIP1 gene:
Search GeneIP for patents involving PBXIP1

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
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PBXIP1 Gene

pre-B-cell leukemia homeobox interacting protein 1

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PBXIP1 Gene

pre-B-cell leukemia homeobox interacting protein 1

Aliasesfor PBXIP1 gene

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Genomic Viewsfor PBXIP1 gene

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Protein Domains /Familiesfor PBXIP1 gene

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for PBXIP1 gene

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Intellectual Property
for PBXIP1 gene

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