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PBXIP1 Gene

protein-coding   GIFtS: 50
GCID: GC01M154916

Pre-B-Cell Leukemia Homeobox Interacting Protein 1

(Previous name: pre-B-cell leukemia transcription factor interacting protein...)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Pre-B-Cell Leukemia Homeobox Interacting Protein 11 2
Pre-B-Cell Leukemia Transcription Factor Interacting Protein 11 2
Hematopoietic PBX-Interacting Protein2 3
HPIP2 3
Pre-B-Cell Leukemia Transcription Factor-Interacting Protein 12

External Ids:    HGNC: 211991   Entrez Gene: 573262   Ensembl: ENSG000001633467   UniProtKB: Q96AQ63   

Export aliases for PBXIP1 gene to outside databases

Previous GC identifers: GC01M151691 GC01M152133 GC01M151729 GC01M153183 GC01M126278


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for PBXIP1 Gene:
PBXIP1 (pre-B-cell leukemia homeobox interacting protein 1) is a protein-coding gene. GO annotations related to this gene include transcription corepressor activity. An important paralog of this gene is CCPG1.

UniProtKB/Swiss-Prot: PBIP1_HUMAN, Q96AQ6
Function: Regulator of pre-B-cell leukemia transcription factors (BPXs) function. Inhibits the binding of PBX1-HOX
complex to DNA and blocks the transcriptional activity of E2A-PBX1. Tethers estrogen receptor-alpha (ESR1) to
microtubules and allows them to influence estrogen receptors-alpha signaling




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000001.10  NC_018912.2  NT_004487.20  
Regulatory elements:
   Regulatory transcription factor binding sites in the PBXIP1 gene promoter:
         c-Rel   p53   AP-1   HOXA5   STAT3   c-Myb   Pax-4a   E47   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidPBXIP1 promoter sequence
   Search Chromatin IP Primers for PBXIP1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat PBXIP1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q21.3   Ensembl cytogenetic band:  1q21.3   HGNC cytogenetic band: 1q22

PBXIP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PBXIP1 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M154916:  view genomic region     (about GC identifiers)

Start:
154,916,552 bp from pter      End:
154,928,599 bp from pter
Size:
12,048 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: PBIP1_HUMAN, Q96AQ6 (See protein sequence)
Recommended Name: Pre-B-cell leukemia transcription factor-interacting protein 1  
Size: 731 amino acids; 80643 Da
Subunit: Interacts with TEX11 (By similarity). Interacts with ESR1, PBX1, PBX2 and PBX3
Secondary accessions: Q5T174 Q5T176 Q9H8X6 Q9HA02 Q9HD85
Alternative splicing: 3 isoforms:  Q96AQ6-1   Q96AQ6-2   Q96AQ6-3   

Explore the universe of human proteins at neXtProt for PBXIP1: NX_Q96AQ6

Explore proteomics data for PBXIP1 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See PBXIP1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_065385.2  
    ENSEMBL proteins: 
     ENSP00000357450   ENSP00000357448   ENSP00000357445   ENSP00000432543   ENSP00000440142  
     ENSP00000438584  

    PBXIP1 Human Recombinant Protein Products:

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    Novus Biologicals PBXIP1 Protein
    Novus Biologicals PBXIP1 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for PBXIP1

     
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    antibodies-online proteins for PBXIP1 (4 products) 

     
    antibodies-online peptides for PBXIP1

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    antibodies-online antibodies for PBXIP1 (17 products) 

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    Cloud-Clone Corp. ELISAs for PBXIP1
    Cloud-Clone Corp. CLIAs for PBXIP1
    Search eBioscience for ELISAs for PBXIP1 
    antibodies-online kits for PBXIP1 (8 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR024139 TF-int_PBXIP1

    Graphical View of Domain Structure for InterPro Entry Q96AQ6

    ProtoNet protein and cluster: Q96AQ6

    UniProtKB/Swiss-Prot: PBIP1_HUMAN, Q96AQ6
    Domain: The C-terminal domain (AA 443-731) contains a nuclear export signal
    Domain: Association to the cytoskeleton through a N-terminal leucine rich-domain (AA 190-218)


    Find genes that share domains with PBXIP1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: PBIP1_HUMAN, Q96AQ6
    Function: Regulator of pre-B-cell leukemia transcription factors (BPXs) function. Inhibits the binding of PBX1-HOX
    complex to DNA and blocks the transcriptional activity of E2A-PBX1. Tethers estrogen receptor-alpha (ESR1) to
    microtubules and allows them to influence estrogen receptors-alpha signaling

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003714transcription corepressor activity NAS10825160
    GO:0005515protein binding IPI16189514
         
    Find genes that share ontologies with PBXIP1           About GenesLikeMe


    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for PBXIP1

    miRNA
    Products:
        
    miRTarBase miRNAs that target PBXIP1:
    hsa-mir-93-5p (MIRT028003), hsa-mir-17-5p (MIRT050995), hsa-mir-130b-3p (MIRT020198), hsa-mir-20a-5p (MIRT050607), hsa-mir-148a-3p (MIRT026000), hsa-mir-296-3p (MIRT038457), hsa-mir-26b-5p (MIRT029484), hsa-mir-335-5p (MIRT017972), hsa-mir-375 (MIRT019795)

    Block miRNA regulation of human, mouse, rat PBXIP1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate PBXIP1 (see all 10):
    hsa-miR-153 hsa-miR-3142 hsa-miR-152 hsa-miR-3679-5p hsa-miR-2115 hsa-miR-148b hsa-miR-129-3p hsa-miR-129*
    SwitchGear 3'UTR luciferase reporter plasmidPBXIP1 3' UTR sequence
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PBXIP1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    PBIP1_HUMAN, Q96AQ6: Cytoplasm, cytoskeleton. Nucleus. Note=Shuttles between the nucleus and the cytosol. Mainly
    localized in the cytoplasm, associated with microtubules. Detected in small amounts in the nucleus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton5
    cytosol5
    nucleus5
    plasma membrane2
    endoplasmic reticulum1
    golgi apparatus1
    mitochondrion1

    Gene Ontology (GO): 5 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus NAS10825160
    GO:0005737cytoplasm ----
    GO:0005829cytosol NAS10825160
    GO:0005874microtubule IEA--
    GO:0043231intracellular membrane-bounded organelle ----

    Find genes that share ontologies with PBXIP1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for PBXIP1
    Interactions:

        Search GeneGlobe Interaction Network for PBXIP1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 18)

    Selected Interacting proteins for PBXIP1 (Q96AQ61, 2, 3 ENSP000003574484) via UniProtKB, MINT, STRING, and/or I2D (see all 23)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CCDC53Q9Y3C01, 2, 3, ENSP000002400794EBI-740845,EBI-712969 MINT-66653 I2D: score=5 STRING: ENSP00000240079
    CCDC85BQ158342, 3, ENSP000003116954MINT-66112 I2D: score=5 STRING: ENSP00000311695
    DPPA2Q7Z7J52, 3MINT-66870 I2D: score=4 
    TSNAXQ995983, ENSP000003555994I2D: score=4 STRING: ENSP00000355599
    BRPF1P552013, ENSP000003733404I2D: score=1 STRING: ENSP00000373340
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007275multicellular organismal development NAS10825160
    GO:0030154cell differentiation NAS10825160
    GO:0045892negative regulation of transcription, DNA-templated NAS10825160

    Find genes that share ontologies with PBXIP1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for PBXIP1 (PBIP1)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for PBXIP1 gene: 
    NM_020524.2  

    Unigene Cluster for PBXIP1:

    Pre-B-cell leukemia homeobox interacting protein 1
    Hs.505806  [show with all ESTs]
    Unigene Representative Sequence: NM_020524
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000368465(uc001ffs.3 uc010pep.2) ENST00000368463(uc001ffr.3)
    ENST00000368460 ENST00000498553 ENST00000490230 ENST00000493133(uc009woy.1)
    ENST00000539880 ENST00000542459
    miRNA
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    Block miRNA regulation of human, mouse, rat PBXIP1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate PBXIP1 (see all 10):
    hsa-miR-153 hsa-miR-3142 hsa-miR-152 hsa-miR-3679-5p hsa-miR-2115 hsa-miR-148b hsa-miR-129-3p hsa-miR-129*
    SwitchGear 3'UTR luciferase reporter plasmidPBXIP1 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for PBXIP1
    Predesigned siRNA for gene silencing in human, mouse, rat PBXIP1
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    OriGene ORF clones in mouse, rat for PBXIP1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: PBXIP1 (NM_020524)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PBXIP1
    Primer
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    OriGene qPCR primer pairs and template standards for PBXIP1
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat PBXIP1
      QuantiTect SYBR Green Assays in human, mouse, rat PBXIP1
      QuantiFast Probe-based Assays in human, mouse, rat PBXIP1

    Additional mRNA sequence: 

    AF221521.1 AK022497.1 AK023219.1 AK300544.1 AK300987.1 AK303413.1 AK303863.1 AK310388.1 
    AK310712.1 AK315551.1 BC016852.1 BC127909.1 BC127910.1 U00952.1 

    Selected DOTS entries (see all 30):

    DT.95223072  DT.454262  DT.121413992  DT.100798438  DT.121414045  DT.95223074  DT.100688115  DT.100798442 
    DT.100798439  DT.100798445  DT.100798440  DT.100040569  DT.121413720  DT.121413995  DT.100042761  DT.91750144 
    DT.95223058  DT.121413844  DT.100689095  DT.100798446  DT.100684934  DT.100798441  DT.121414009  DT.121414023 

    Selected AceView cDNA sequences (see all 318):

    BC016852 BU734322 CB268473 CA396664 AI687418 CK820424 BU782598 BM822778 
    AI784101 BM710511 CA396235 AI573267 AA723588 BU733549 BU783591 BM716297 
    BQ270417 AA363257 AA082499 CA395729 CK820423 BM695124 BM826888 BQ929051 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for PBXIP1 (see all 26)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b · 2c · 2d ^ 3a · 3b · 3c · 3d · 3e ^ 4 ^ 5a · 5b · 5c · 5d ^ 6a · 6b · 6c · 6d ^ 7a · 7b · 7c · 7d ^ 8a ·
    SP1:                    -     -     -     -     -                       -     -     -     -                 -     -                                         -   
    SP2:                    -     -     -     -     -                       -     -     -     -                 -     -                                         -   
    SP3:                    -     -     -     -     -     -     -     -     -     -     -     -                 -     -                                         -   
    SP4:                    -     -     -     -     -                       -     -     -     -                 -     -                                         -   
    SP5:                    -     -     -     -     -                       -     -     -     -                 -     -                             -     -     -   

    ExUns: 8b · 8c · 8d · 8e ^ 9a · 9b · 9c · 9d ^ 10 ^ 11a · 11b ^ 12a · 12b · 12c ^ 13 ^ 14 ^ 15
    SP1:                                                                                -                     
    SP2:                                                                                -                     
    SP3:                                                                                -                     
    SP4:                                -     -     -                                                         
    SP5:  -     -     -     -     -     -     -     -     -     -                                             


    ECgene alternative splicing isoforms for PBXIP1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    PBXIP1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTGACCGGTG
    PBXIP1 Expression
    About this image


    PBXIP1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 13) fully expand
     
     Blood (Hematopoietic System)    fully expand to see all 2 entries
             Peripheral blood-derived hematopoietic stem cells (family)
     
     Ovary (Reproductive System)
             Mature follicles
     
     Thymus (Hematopoietic System)
     
     Uterus (Reproductive System)
     
     Thyroid (Endocrine System)
    PBXIP1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    PBXIP1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.505806

    UniProtKB/Swiss-Prot: PBIP1_HUMAN, Q96AQ6
    Tissue specificity: Expressed in early hematopoietic precursors

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PBXIP1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for PBXIP1 gene from Selected species (see all 8)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Pbxip11 , 5 pre B cell leukemia transcription factor interacting more1, 5 79.34(n)1
    72.11(a)1
      3 (39.12 cM)5
    2295341  NM_146131.21  NP_666243.11 
     894367065 
    zebrafish
    (Danio rerio)
    Actinopterygii PBXIP16
    pre-B-cell leukemia homeobox interacting protein 1...
    21(a)
    1 → many
    Zv9_NA603(3916-14633) ENSDARG00000089453


    ENSEMBL Gene Tree for PBXIP1 (if available)
    TreeFam Gene Tree for PBXIP1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for PBXIP1 gene
    CCPG12  

    Find genes that share paralogs with PBXIP1           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for PBXIP1
    PGOHUM00000244278


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for PBXIP1 (see all 292)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
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    ----------
    rs21024231,2
    C,F,O,A,H--154916068(+) AATGAG/ACTAAT 1 -- int119Minor allele frequency- A:0.30NS EA NA WA CSA 1090
    rs23354091,2
    C,F,O,A,H--154916106(+) TATTCA/GCTTGC 1 -- int115Minor allele frequency- G:0.49NS EA NA CSA WA 926
    rs1837274751,2
    --154916250(+) ATTGCC/TGAAGG 1 -- int10--------
    rs570778871,2
    C,F--154916293(+) GAGAAT/CAGCCA 1 -- int11Minor allele frequency- C:0.16WA 118
    rs612017361,2
    F--154916310(+) GTCTGG/CTCATC 1 -- int11Minor allele frequency- C:0.03EA 120
    rs1907983181,2
    --154916380(+) GGGGAC/TAGTGA 1 -- int10--------
    rs1395592031,2
    C--154916418(+) AAATGA/GAGCCA 1 -- int10--------
    rs412642451,2
    C,F--154916465(+) CAGAAG/ACTCTT 1 -- int11Minor allele frequency- A:0.03NA 120
    rs412642471,2
    --154916489(+) GGTTCC/TTTTCC 1 -- int10--------
    rs1869809141,2
    --154916535(+) TTTGAA/GTGCCC 1 -- int10--------

    HapMap Linkage Disequilibrium report for PBXIP1 (154916552 - 154928599 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for PBXIP1:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2718374CNV Deletion23290073
    nsv509502CNV Insertion20534489
    nsv872454CNV Loss21882294
    nsv872453CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for PBXIP1 gene, integrated from 10 sources (see all 26):
    (articles sorted by number of sources associating them with PBXIP1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Functional cloning and characterization of a novel nonhomeodomain protein that inhibits the binding of PBX1-HOX complexes to DNA. (PubMed id 10825160)1, 2, 3 Abramovich C.... Humphries R.K. (J. Biol. Chem. 2000)
    2. Functional characterization of multiple domains involved in the subcellular localization of the hematopoietic Pbx interacting protein (HPIP). (PubMed id 12360403)1, 2, 9 Abramovich C.... Humphries R.K. (Oncogene 2002)
    3. An inherent role of microtubule network in the action of nuclear receptor. (PubMed id 17043237)1, 2 Manavathi B.... Kumar R. (Proc. Natl. Acad. Sci. U.S.A. 2006)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. Expression of (cac)n/(gtg)n simple repetitive sequences in mRNA of human lymphocytes. (PubMed id 7505766)1, 3 Epplen C. and Epplen J.T. (Hum. Genet. 1994)
    6. Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array. (PubMed id 23535732)1 Eeles R.A....Easton D.F. (Nat. Genet. 2013)
    7. Functional regulation of pre-B-cell leukemia homeobox interacting protein 1 (PBXIP1/HPIP) in erythroid differentiation. (PubMed id 22187427)1 Manavathi B....Humphries R.K. (J. Biol. Chem. 2012)
    8. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (Mol. Syst. Biol. 2011)
    9. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    10. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (Sci. Signal. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

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    Entrez Gene: 57326 HGNC: 21199 AceView: PBXIP1 Ensembl:ENSG00000163346 euGenes: HUgn57326
    ECgene: PBXIP1 H-InvDB: PBXIP1

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for PBXIP1 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for PBXIP1 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for PBXIP1 gene:
    Search GeneIP for patents involving PBXIP1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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