Aliases for PBX2 Gene
External Ids for PBX2 Gene
Previous GeneCards Identifiers for PBX2 Gene
This gene encodes a ubiquitously expressed member of the TALE/PBX homeobox family. It was identified by its similarity to a homeobox gene which is involved in t(1;19) translocation in acute pre-B-cell leukemias. This protein is a transcriptional activator which binds to the TLX1 promoter. The gene is located within the major histocompatibility complex (MHC) on chromosome 6. [provided by RefSeq, Jul 2008]
GeneCards Summary for PBX2 Gene
PBX2 (Pre-B-Cell Leukemia Homeobox 2) is a Protein Coding gene. Diseases associated with PBX2 include duodenal gastrinoma and pancreatic gastrinoma. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and chromatin binding. An important paralog of this gene is PBX3.
UniProtKB/Swiss-Prot for PBX2 Gene
Transcriptional activator that binds the sequence 5-ATCAATCAA-3. Activates transcription of PF4 in complex with MEIS1.