PBRM1 Gene
protein-coding GIFtS: 55
GCID: GC03M052579
|
|
polybromo 1
| |
Aliases
for PBRM1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Polybromo 11 2 | | Polybromo-1D3 | | BAF1801 2 3 5 | | Protein Polybromo-12 | | PB11 2 3 5 | | Polybromo-1D3 | | BRG1-Associated Factor 1802 3 | | HPB11 |
Export aliases for PBRM1 gene to outside databasesPrevious GC identifer: GC03M052554 |
Summaries
for PBRM1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for PBRM1:
This locus encodes a subunit of ATP-dependent chromatin-remodeling complexes. The encoded protein has been identifiedas in integral component of complexes necessary for ligand-dependent transcriptional activation by nuclear hormonereceptors. Mutations at this locus have been associated with primary clear cell renal cell carcinoma. (provided byRefSeq, Feb 2012)
UniProtKB/Swiss-Prot: PB1_HUMAN, Q86U86Function: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration ofDNA-nucleosome topology). Acts as a negative regulator of cell proliferation
Gene Wiki entry for PBRM1
|
Genomic Views
for PBRM1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000003.11 NC_018914.1 NT_022517.18
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the PBRM1 gene promoter:
AP-1 ATF-2
Other transcription factors
Search SABiosciences Chromatin IP Primers for PBRM1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PBRM1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 3p21 Ensembl cytogenetic band: 3p21.1 HGNC cytogenetic band: 3p21PBRM1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 3 GeneLoc Exon Structure GeneLoc location for GC03M052579: view genomic region
(about GC identifiers)
Start:
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52,579,368 bp from pter |
End:
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52,719,933 bp from pter |
Size:
|
140,566 bases |
Orientation:
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minus strand |
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Proteins
for PBRM1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: PB1_HUMAN, Q86U86 (See
protein sequence)Recommended Name: Protein polybromo-1 Size: 1689 amino acids; 192948 Da
Subunit: Component of the SWI/SNF-B (PBAF) chromatin-remodeling complex, which contains at least SMARCA4/BRG1,SMARCB1/SNF5/INI1/BAF47, ACTL6A/BAF53A or ACTL6B/BAF53B, SMARCE1/BAF57, SMARCD1/BAF60A, SMARCD2/BAF60B, perhapsSMARCD3/BAF60C, SMARCC1/BAF155, SMARCC2/BAF170, PB1/BAF180, ARID2/BAF200, ARID1A/BAF250A or ARID1B/BAF250B and actin.Interacts with PHF10/BAF45A (By similarity)
Subcellular location: Nucleus
Sequence caution: Sequence=AAI15010.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence;Sequence=AAI15011.1; Type=Erroneous initiation; Sequence=AAI15012.1; Type=Erroneous termination; Positions=78;Note=Translated as Arg; Sequence=BAB71210.1; Type=Erroneous initiation;
6/9 PDB 3D structures from  and Proteopedia  for PBRM1 (see all 9):2KTB (3D)
3G0J (3D)
3HMF (3D)
3IU5 (3D)
3IU6 (3D)
3K2J (3D)
Secondary accessions: A1L381 A1L382 A4FUJ7 Q1RMD1 Q1RMD2 Q96MS2 Q9H2T3 Q9H2T4 Q9H2T5 Q9H301 Q9H314Alternative splicing: 9 isoforms: Q86U86-1 Q86U86-2 Q86U86-3 Q86U86-4 Q86U86-5 Q86U86-6 Q86U86-7 Q86U86-8 Q86U86-9 Explore the universe of human proteins at neXtProt for PBRM1: NX_Q86U86
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q86U86
PBRM1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_060783.3
ENSEMBL proteins: ENSP00000349213 ENSP00000378307 ENSP00000296302 ENSP00000338302 ENSP00000404579 ENSP00000386593 ENSP00000386529 ENSP00000386643 ENSP00000386601 ENSP00000387775 ENSP00000397662 ENSP00000409939 ENSP00000389390 ENSP00000412401 ENSP00000416851 ENSP00000404635 ENSP00000411895 ENSP00000397399
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
PBRM1 for ontologies About GeneDecksing
PBRM1 Antibody Products:
Assay Products for PBRM1: |
Protein
Domains /
Families
for PBRM1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
PBRM1 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q86U86ProtoNet protein and cluster: Q86U86 1 Blocks protein family: IPB001025 Bromo adjacent region
UniProtKB/Swiss-Prot: PB1_HUMAN, Q86U86Similarity: Contains 2 BAH domainsSimilarity: Contains 6 bromo domainsSimilarity: Contains 1 HMG box DNA-binding domain |
Function
for PBRM1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: PB1_HUMAN, Q86U86Function: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration ofDNA-nucleosome topology). Acts as a negative regulator of cell proliferation
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PBRM1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PBRM1 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): PBRM1 (NM_181042) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for PBRM1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PBRM1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PBRM1 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
PBRM1 for ontologies About GeneDecksing
Animal Models:
5 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Pbrm1):
PBRM1 for phenotypes About GeneDecksing
|
Pathways & Interactions
for PBRM1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for PBRM1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/609 Interacting proteins for PBRM1 (Q86U861, 2, 3 ENSP000003492134) via UniProtKB, MINT, STRING, and/or I2D (see all 609)About this table
Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7): About this table
PBRM1 for ontologies About GeneDecksing
|
Drugs & Compounds
for PBRM1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for PBRM1
Search CenterWatch for drugs/clinical trials and news about PBRM1 / PB1
|
Transcripts
for PBRM1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for PBRM1 gene (4 alternative transcripts): NM_018313.4 NM_018165.4 NM_181041.1 NM_181042.3 Unigene Cluster for PBRM1: Polybromo 1 Hs.189920 [show with all ESTs]Unigene Representative Sequence: NM_01831318/20 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 20): ENST00000356770(uc003dex.2 uc003deq.2 uc003der.2 uc003des.2 uc003det.2 uc003deu.2 uc003dev.2 uc003dew.2 uc010hmk.1 uc003dey.2)
ENST00000394830 ENST00000296302 ENST00000337303 ENST00000412587 ENST00000409057(uc003dez.1)
ENST00000410007 ENST00000409114 ENST00000409767(uc003dfb.1) ENST00000423351
ENST00000462207(uc003dfa.1) ENST00000446103 ENST00000480064(uc003dfc.3)
ENST00000431678 ENST00000420148 ENST00000449505 ENST00000450271 ENST00000439181
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PBRM1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PBRM1 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 3): PBRM1 (NM_181042) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for PBRM1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PBRM1 |
Additional cDNA sequence: AF177387.1 AF197569.1 AF225870.1 AF225871.1 AF225872.1 AK000151.1 AK001507.1 AK001926.1 AK056541.1 AL050083.1 AY281068.1 BC015323.1 BC070273.1 BC089409.1 BC115009.1 BC115010.1 BC115011.1 BC116450.1 BC129934.1 BC129935.1 22 DOTS entries: DT.100726463 DT.447326 DT.100785845 DT.102835857 DT.211516 DT.92066151 DT.40132525 DT.40132524 DT.100785843 DT.120869636 DT.97820929 DT.99982226 DT.120869863 DT.120869783 DT.100785844 DT.451847 DT.102830161 DT.102830164 DT.120869800 DT.40203201 DT.95318167 DT.95318189 24/310 AceView cDNA sequences (see all 310): AU136671 NM_181041 AF225872 AI368753 AF177387 F01587 CA312527 BF592839 AF225870 BM724425 BG231839 BU738578 AK001926 BX480769 AA054095 AI126736 AW204349 BC015323 BG059884 AI650822 BE465515 AW444726 AK001507 AA961599
GeneLoc Exon Structure
5/7 Alternative Splicing Database (ASD) splice patterns (SP) for PBRM1 (see all 7) About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15a | · | 15b | ^ | 16a | · | 16b | · | 16c | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20 | ^ | 21 | ^ | 22 | ^ | 23a | · |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | |
| ExUns: | 23b | ^ | 24 | ^ | 25 | ^ | 26 | ^ | 27 | ^ | 28 | ^ | 29 | ^ | 30 | ^ | 31a | · | 31b | ^ | 32 |
|---|
|
| SP1: | | | | | | | | | - | | - | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for PBRM1
|
Expression
for PBRM1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| PBRM1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TATGTATCTT
About this image
See PBRM1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for PBRM1
SOURCE GeneReport for Unigene cluster: Hs.189920
UniProtKB/Swiss-Prot: PB1_HUMAN, Q86U86Tissue specificity: Widely expressed
SABiosciences Expression via Pathway-Focused PCR Arrays including PBRM1: | Polycomb & Trithorax Complexes in human mouse rat | | Epigenetic Chromatin Remodeling Factors in human mouse rat |
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PBRM1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat PBRM1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PBRM1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PBRM1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PBRM1 |
Orthologs
for PBRM1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for PBRM1 gene from 7/24 species (see all 24) About this table
ENSEMBL Gene Tree for PBRM1 (if available)
TreeFam Gene Tree for PBRM1 (if available) |
Paralogs
for PBRM1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for PBRM1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 3 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for PBRM1 (52579368 - 52719933 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 8 variations for PBRM1
1 CNV: 98313
7 Indels: 46419 46420 62058 27333 60419 40534 42704 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PBRM1 |
|
Disorders
/ Diseases
for PBRM1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
PBRM1 for disorders About GeneDecksing
OMIM gene information: 606083
OMIM disorders: --
UniProtKB/Swiss-Prot: PB1_HUMAN, Q86U86
Defects in PBRM1 are a cause of renal cell carcinoma (RCC) [MIM:144700]. It is a heterogeneous group ofsporadic or hereditary carcinoma derived from cells of the proximal renal tubular epithelium. It is subclassified intoclear cell renal carcinoma (non-papillary carcinoma), papillary renal cell carcinoma, chromophobe renal cellcarcinoma, collecting duct carcinoma with medullary carcinoma of the kidney, and unclassified renal cell carcinoma
14  diseases for PBRM1: About MalaCardsrenal cell carcinoma clear cell renal cell carcinoma carcinoma collecting duct carcinoma
chromophobe renal cell carcinoma papillary renal cell carcinoma mood disorder bipolar disorder
kidney cancer influenza lung cancer breast cancer
schizophrenia neuronitis
1 disease from the University of Copenhagen DISEASES database for PBRM1:Influenza Human Genome Epidemiology (HuGE) Navigator: PBRM1 (3 documents)
Export disorders for PBRM1 gene to outside databases
|
Publications
for PBRM1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for PBRM1 gene, integrated from 9 sources (see all 60):
(articles sorted by number of sources associating them with PBRM1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The human SWI/SNF-B chromatin-remodeling complex is related to yeast rsc and localizes at kinetochores of mitotic chromosomes. (PubMed id 11078522)1, 2, 3 Xue Y.... Wang W. (2000)
- The 3p21 candidate tumor suppressor gene BAF180 is normally expressed in human lung cancer. (PubMed id 15735765)1, 2, 9 Sekine I.... Minna J.D. (2005)
- Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma. (PubMed id 21248752)1, 2 Varela I....Futreal P.A. (2011)
- A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)1, 2 Beausoleil S.A.... Gygi S.P. (2006)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
- PBAF chromatin-remodeling complex requires a novel specificity subunit, BAF200, to regulate expression of selective interferon- responsive genes. (PubMed id 15985610)1, 2 Yan Z.... Wang W. (2005)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Recent advances in understanding chromatin remodeling by SWI/SNF complexes. (PubMed id 12672490)1, 2 Martens J.A. and Winston F. (2003)
- cDNA cloning of the human polybromo-1 gene on chromosome 3p21. (PubMed id 12487023)1, 2 Horikawa I. and Barrett J.C. (2002)
- Gene expression profiling in human fetal liver and identification of tissue- and developmental-stage-specific genes through compiled expression profiles and efficient cloning of full-length cDNAs. (PubMed id 11483580)1, 3 Yu Y....He F. (2001)
|
External Searches for PBRM1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing PBRM1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing PBRM1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing PBRM1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for PBRM1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for PBRM1 gene:
Search GeneIP for patents involving PBRM1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for PBRM1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for PBRM1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for PBRM1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PBRM1 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for PBRM1 | | OriGene 3'-UTR Clone for PBRM1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PBRM1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PBRM1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for PBRM1 | | OriGene Custom Protein Services for PBRM1 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat PBRM1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PBRM1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PBRM1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat PBRM1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PBRM1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PBRM1 |
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| | | | Search Tocris compounds for PBRM1 |
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 | | | PBRM1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PBRM1 |
|  |  |  | | | | Search ThermoFisher Antibodies for PBRM1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PBRM1 |
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