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Aliases for PBOV1 Gene

Aliases for PBOV1 Gene

  • Prostate And Breast Cancer Overexpressed 1 2 3 5
  • UROC28 3 4
  • UC28 3 4
  • Protein UROC28 4
  • DJ171N11.2 3

External Ids for PBOV1 Gene

Previous GeneCards Identifiers for PBOV1 Gene

  • GC06M138472
  • GC06M138517
  • GC06M138578

Summaries for PBOV1 Gene

Entrez Gene Summary for PBOV1 Gene

  • This intronless gene encodes a protein of unknown function. Its expression is up-regulated in some types of cancer, including prostate, breast, and bladder cancer. [provided by RefSeq, Aug 2011]

GeneCards Summary for PBOV1 Gene

PBOV1 (Prostate And Breast Cancer Overexpressed 1) is a Protein Coding gene.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PBOV1 Gene

Genomics for PBOV1 Gene

Regulatory Elements for PBOV1 Gene

Enhancers for PBOV1 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around PBOV1 on UCSC Golden Path with GeneCards custom track

Genomic Location for PBOV1 Gene

138,215,986 bp from pter
138,218,491 bp from pter
2,506 bases
Minus strand

Genomic View for PBOV1 Gene

Genes around PBOV1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
PBOV1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PBOV1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PBOV1 Gene

Proteins for PBOV1 Gene

  • Protein details for PBOV1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Prostate and breast cancer overexpressed gene 1 protein
    Protein Accession:

    Protein attributes for PBOV1 Gene

    135 amino acids
    Molecular mass:
    15722 Da
    Quaternary structure:
    No Data Available

neXtProt entry for PBOV1 Gene

Proteomics data for PBOV1 Gene at MOPED

Post-translational modifications for PBOV1 Gene

No Post-translational modifications

Other Protein References for PBOV1 Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

  • Abcam antibodies for PBOV1
  • Santa Cruz Biotechnology (SCBT) Antibodies for PBOV1

No data available for DME Specific Peptides for PBOV1 Gene

Domains & Families for PBOV1 Gene

Protein Domains for PBOV1 Gene


Suggested Antigen Peptide Sequences for PBOV1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with PBOV1: view

No data available for Gene Families and UniProtKB/Swiss-Prot for PBOV1 Gene

Function for PBOV1 Gene

Phenotypes for PBOV1 Gene

genes like me logo Genes that share phenotypes with PBOV1: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for PBOV1 Gene

Localization for PBOV1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for PBOV1 Gene

Cytoplasm. Nucleus.

Subcellular locations from

Jensen Localization Image for PBOV1 Gene COMPARTMENTS Subcellular localization image for PBOV1 gene
Compartment Confidence
nucleus 3

Gene Ontology (GO) - Cellular Components for PBOV1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IEA --
genes like me logo Genes that share ontologies with PBOV1: view

Pathways & Interactions for PBOV1 Gene

SuperPathways for PBOV1 Gene

No Data Available

Interacting Proteins for PBOV1 Gene

Gene Ontology (GO) - Biological Process for PBOV1 Gene


No data available for Pathways by source and SIGNOR curated interactions for PBOV1 Gene

Drugs & Compounds for PBOV1 Gene

No Compound Related Data Available

Transcripts for PBOV1 Gene

mRNA/cDNA for PBOV1 Gene

(1) REFSEQ mRNAs :
(4) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for PBOV1 Gene

No ASD Table

Relevant External Links for PBOV1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for PBOV1 Gene

mRNA expression in normal human tissues for PBOV1 Gene

mRNA differential expression in normal tissues according to GTEx for PBOV1 Gene

This gene is overexpressed in Brain - Cerebellum (x10.4) and Brain - Cerebellar Hemisphere (x5.3).

SOURCE GeneReport for Unigene cluster for PBOV1 Gene Hs.302016

mRNA Expression by UniProt/SwissProt for PBOV1 Gene

Tissue specificity: Expressed in colon, prostate, small intestine, testis and spleen, with lower expression in thymus, ovary, and peripheral blood leukocytes. Up-regulated expression in prostate, breast, and bladder cancer, but not in lung and colon cancer.
genes like me logo Genes that share expression patterns with PBOV1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression and Protein tissue co-expression partners for PBOV1 Gene

Orthologs for PBOV1 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for PBOV1 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia PBOV1 35
  • 99.75 (n)
  • 100 (a)
Species with no ortholog for PBOV1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for PBOV1 Gene

Gene Tree for PBOV1 (if available)
Gene Tree for PBOV1 (if available)

Paralogs for PBOV1 Gene

No data available for Paralogs for PBOV1 Gene

Variants for PBOV1 Gene

Sequence variations from dbSNP and Humsavar for PBOV1 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
VAR_059707 -

Variation tolerance for PBOV1 Gene

Residual Variation Intolerance Score: 77.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.67; 78.47% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for PBOV1 Gene

Disorders for PBOV1 Gene

Relevant External Links for PBOV1

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for PBOV1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for PBOV1 Gene

Publications for PBOV1 Gene

  1. Cloning and characterization of UROC28, a novel gene overexpressed in prostate, breast, and bladder cancers. (PMID: 11156405) An G. … Veltri R.W. (Cancer Res. 2000) 2 3 4 67
  2. Enhanced expression of the UROC28 gene in human breast cancer: relationship to ERBB2 gene expression. (PMID: 12553037) Kamagata C. … Watanabe N. (Anticancer Res. 2002) 2 3 23
  3. PBOV1 is a human de novo gene with tumor-specific expression that is associated with a positive clinical outcome of cancer. (PMID: 23418531) Samusik N. … Kozlov A.P. (PLoS ONE 2013) 3
  4. Genetic variation in genes interacting with BRCA1/2 and risk of breast cancer in the Cypriot population. (PMID: 19714462) Loizidou M.A. … Kyriacou K. (Breast Cancer Res. Treat. 2010) 3
  5. Bone morphogenic factor gene dosage abnormalities in prostatic intraepithelial neoplasia and prostate cancer. (PMID: 17656261) Doak S.H. … Parry J.M. (Cancer Genet. Cytogenet. 2007) 3

Products for PBOV1 Gene

Sources for PBOV1 Gene