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PATL1 Gene

protein-coding   GIFtS: 50
GCID: GC11M059404

Protein Associated With Topoisomerase II Homolog 1 (Yeast)

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Protein Associated With Topoisomerase II Homolog 1 (Yeast)1 2     PAT1-Like Protein 12 3
Protein PAT1 Homolog B2 3     Protein PAT1 Homolog 12
Pat1b2 3     PAT1B5
hPat1b2 3     

External Ids:    HGNC: 267211   Entrez Gene: 2199882   Ensembl: ENSG000001668897   OMIM: 6146605   UniProtKB: Q86TB93   

Export aliases for PATL1 gene to outside databases

Previous GC identifers: GC11M059161 GC11M055751


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for PATL1 Gene:
PATL1 (protein associated with topoisomerase II homolog 1 (yeast)) is a protein-coding gene. GO annotations related to this gene include RNA binding and poly(G) binding. An important paralog of this gene is PATL2.

UniProtKB/Swiss-Prot: PATL1_HUMAN, Q86TB9
Function: RNA-binding protein involved in deadenylation-dependent decapping of mRNAs, leading to the degradation
of mRNAs. Acts as a scaffold protein that connects deadenylation and decapping machinery. Required for
cytoplasmic mRNA processing body (P-body) assembly. In case of infection, required for translation and
replication of hepatitis C virus (HCV)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000011.9  NT_167190.2  NC_018922.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the PATL1 gene promoter:
         HFH-3   Max1   HOXA9   HOXA9B   POU3F1   Arnt   Meis-1b   FOXI1   Meis-1   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidPATL1 promoter sequence
   Search Chromatin IP Primers for PATL1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat PATL1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q12.1   Ensembl cytogenetic band:  11q12.1   HGNC cytogenetic band: 11q12.1

PATL1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PATL1 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11M059404:  view genomic region     (about GC identifiers)

Start:
59,404,189 bp from pter      End:
59,436,511 bp from pter
Size:
32,323 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: PATL1_HUMAN, Q86TB9 (See protein sequence)
Recommended Name: Protein PAT1 homolog 1  
Size: 770 amino acids; 86850 Da
Subunit: Interacts (via region A) with DDX6/RCK. Interacts (via region H and region C) with LSM1 and LSM4.
Interacts (via region N) with DCP1A, DCP2, EDC3, EDC4 and XRN1. Interacts with the CCR4-NOT complex. Interacts
with the Lsm-containing SMN-Sm protein complex
Sequence caution: Sequence=CAD89916.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
3 PDB 3D structures from and Proteopedia for PATL1:
2XEQ (3D)        2XER (3D)        2XES (3D)    
Secondary accessions: B3KXT9 Q2TA86 Q6P166 Q8N9M6 Q8NI63
Alternative splicing: 4 isoforms:  Q86TB9-1   Q86TB9-2   Q86TB9-3   Q86TB9-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for PATL1: NX_Q86TB9

Explore proteomics data for PATL1 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See PATL1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_689929.2  
    ENSEMBL proteins: 
     ENSP00000300146  
    Reactome Protein details: Q86TB9

    PATL1 Human Recombinant Protein Products:

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    antibodies-online proteins for PATL1 (2 products) 

     
    antibodies-online peptides for PATL1

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR019167 Topo_II-assoc_PAT1

    Graphical View of Domain Structure for InterPro Entry Q86TB9

    ProtoNet protein and cluster: Q86TB9

    UniProtKB/Swiss-Prot: PATL1_HUMAN, Q86TB9
    Domain: The region A, also named N-term, mediates the interaction with DDX6/RCK and is required for cytoplasmic
    mRNA processing body assembly
    Domain: The region C, also named Pat-C, is required for RNA-binding and mediates the binding with the
    Lsm-containing SMN-Sm protein complex and the decapping machinery. It folds into an alpha-alpha superhelix,
    exposing conserved and basic residues on one side of the domain
    Similarity: Belongs to the PAT1 family


    Find genes that share domains with PATL1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: PATL1_HUMAN, Q86TB9
    Function: RNA-binding protein involved in deadenylation-dependent decapping of mRNAs, leading to the degradation
    of mRNAs. Acts as a scaffold protein that connects deadenylation and decapping machinery. Required for
    cytoplasmic mRNA processing body (P-body) assembly. In case of infection, required for translation and
    replication of hepatitis C virus (HCV)

         Gene Ontology (GO): 5 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003723RNA binding IDA--
    GO:0005515protein binding IPI--
    GO:0008266poly(U) RNA binding IDA--
    GO:0034046poly(G) binding IDA--
    GO:0044822poly(A) RNA binding IDA--
         
    Find genes that share ontologies with PATL1           About GenesLikeMe


    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for PATL1

    miRNA
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    miRTarBase miRNAs that target PATL1:
    hsa-mir-19b-3p (MIRT031120), hsa-mir-196a-5p (MIRT048252)

    Block miRNA regulation of human, mouse, rat PATL1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate PATL1 (see all 36):
    hsa-miR-136 hsa-miR-300 hsa-miR-298 hsa-miR-3613-3p hsa-miR-34b hsa-miR-3163 hsa-miR-381 hsa-miR-188-3p
    SwitchGear 3'UTR luciferase reporter plasmidPATL1 3' UTR sequence
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    PATL1_HUMAN, Q86TB9: Cytoplasm, P-body. Nucleus. Nucleus, PML body. Nucleus speckle. Note=Predominantly
    cytoplasmic. Shuttles between the nucleus and the cytoplasm in a CRM1-dependent manner. Enriched in splicing
    speckles. Localization to nuclear foci and speckles requires active transcription. Excluded from the nucleolus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol4

    Gene Ontology (GO): Selected cellular component terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000932cytoplasmic mRNA processing body IDA--
    GO:0005829cytosol TAS--
    GO:0016605PML body IEA--
    GO:0016607nuclear speck IEA--
    GO:0030014colocalizes with CCR4-NOT complex IDA--

    Find genes that share ontologies with PATL1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for PATL1 About    
    See pathways by source

    SuperPathContained pathways About
    1Deadenylation-dependent mRNA decay
    Deadenylation-dependent mRNA decay0.48
    mRNA Decay by 5 to 3' Exoribonuclease0.00
    RNA degradation0.48
    2Gene Expression
    Gene Expression0.40


    Find genes that share SuperPaths with PATL1           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Reactome Pathway for PATL1
        mRNA decay by 5' to 3' exoribonuclease


    1 Kegg Pathway  (Kegg details for PATL1):
        RNA degradation

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for PATL1
    Interactions:

        Search GeneGlobe Interaction Network for PATL1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for PATL1 (Q86TB93 ENSP000003001464) via UniProtKB, MINT, STRING, and/or I2D (see all 113)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    EXOC5O004713I2D: score=4 
    KBTBD7Q8WVZ93I2D: score=1 
    EDC4ENSP000003518114STRING: ENSP00000351811
    DDX6ENSP000002640184STRING: ENSP00000264018
    LSM1ENSP000003105964STRING: ENSP00000310596
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000288nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay TAS--
    GO:0000290deadenylation-dependent decapping of nuclear-transcribed mRNA IDA--
    GO:0010467gene expression TAS--
    GO:0016070RNA metabolic process TAS--
    GO:0016071mRNA metabolic process TAS--

    Find genes that share ontologies with PATL1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
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    Browse Tocris compounds for PATL1



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for PATL1 gene: 
    NM_152716.2  

    Unigene Cluster for PATL1:

    Protein associated with topoisomerase II homolog 1 (yeast)
    Hs.591960  [show with all ESTs]
    Unigene Representative Sequence: NM_152716
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000300146(uc001noe.4 uc009yms.1) ENST00000531919
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate PATL1 (see all 36):
    hsa-miR-136 hsa-miR-300 hsa-miR-298 hsa-miR-3613-3p hsa-miR-34b hsa-miR-3163 hsa-miR-381 hsa-miR-188-3p
    SwitchGear 3'UTR luciferase reporter plasmidPATL1 3' UTR sequence
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    Additional mRNA sequence: 

    AB065087.1 AK094193.1 AK127649.1 AK127943.1 AK293213.1 AL831992.2 BC023255.1 BC048309.1 
    BC065264.1 BC109038.1 BC109039.1 BC111047.1 

    4 DOTS entries:

    DT.212302  DT.100779306  DT.99982546  DT.95276145 

    Selected AceView cDNA sequences (see all 216):

    AA406642 BC065264 BQ440594 BM742405 AI769103 AK094193 BM905875 BE466679 
    BF433898 BQ009844 AI692780 CR610274 AA765123 CF243078 BE644676 AA227960 
    AA609954 AI266734 AA862001 AA633160 BU626719 BQ424500 AI302415 AB065087 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for PATL1    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11a · 11b ^ 12 ^ 13 ^ 14a · 14b ^ 15 ^ 16a · 16b ^ 17a · 17b ^ 18 ^ 19
    SP1:                                                                                                  -                                             
    SP2:                                            -                                                     -                 -     -                     
    SP3:                                                                                                                                                


    ECgene alternative splicing isoforms for PATL1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    PATL1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCTTTCCTAC
    PATL1 Expression
    About this image

    PATL1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    PATL1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.591960

    UniProtKB/Swiss-Prot: PATL1_HUMAN, Q86TB9
    Tissue specificity: Ubiquitous

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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for PATL1 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Patl11 , 5 protein associated with topoisomerase II homolog 1 more1, 5 92.68(n)1
    96.49(a)1
      19 (8.57 cM)5
    2259291  NM_172635.31  NP_766223.21 
     119123995 
    chicken
    (Gallus gallus)
    Aves OSBP1 oxysterol binding protein 71.79(n)
    79.7(a)
      426566  XM_424206.4  XP_424206.4 
    lizard
    (Anolis carolinensis)
    Reptilia PATL16
    protein associated with topoisomerase II homolog 1...
    80(a)
    1 ↔ 1
    1(90978972-90993875)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.66302 Xenopus laevis transcribed sequence with weak similarity more 75.57(n)    BU911618.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufa11d042 wufa11d04 80.39(n)   334986  CD592579.1 


    ENSEMBL Gene Tree for PATL1 (if available)
    TreeFam Gene Tree for PATL1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for PATL1 gene
    PATL22  
    1 SIMAP similar gene for PATL1 using alignment to 1 protein entry:     PATL1_HUMAN:
    PATL2

    Find genes that share paralogs with PATL1           About GenesLikeMe


    2 Pseudogenes.org Pseudogenes for PATL1
    PGOHUM00000234314 PGOHUM00000236775


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for PATL1 (see all 653)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1869174651,2
    --59403699(+) CTTGAA/GCATTT 1 -- int10--------
    rs605995291,2
    --59403748(+) TAAATA/TCACTA 1 -- int10--------
    rs1918144231,2
    --59403751(+) ATTCAC/TTATAA 1 -- int10--------
    rs1510094661,2
    C--59403796(+) GATGAA/GTTTTG 1 -- int10--------
    rs1409051841,2
    C--59404135(+) ATATGC/TTAGAA 1 -- int10--------
    rs112300301,2
    C,H--59404138(+) TGCTAG/AAAACA 1 -- int16Minor allele frequency- A:0.00NS EA NA 420
    rs764788831,2
    C--59404387(+) ACAACG/AGTAGA 1 -- ut313Minor allele frequency- A:0.10NA EA 242
    rs1501281531,2
    C--59404430(+) GGTGGA/GGCCTG 1 -- ut310--------
    rs1386015681,2
    --59404525(+) GTGCAA/TAATGT 1 -- ut310--------
    rs1842916641,2
    --59404581(+) ACATTA/CGAAAA 1 -- ut310--------

    HapMap Linkage Disequilibrium report for PATL1 (59404189 - 59436511 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for PATL1:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2469731CNV Insertion19546169
    nsv832172CNV Loss17160897
    nsv819971CNV Loss19587683

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing PATL1
    DNA2.0 Custom Variant and Variant Library Synthesis for PATL1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 614660    OMIM disorders: --


    Find genes that share disorders with PATL1           About GenesLikeMe


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    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for PATL1 gene, integrated from 10 sources (see all 32):
    (articles sorted by number of sources associating them with PATL1)
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    1. Identification of PatL1, a human homolog to yeast P body component Pat1. (PubMed id 17936923)1, 2, 3 Scheller N.... Diez J. (Biochim. Biophys. Acta 2007)
    2. RNA-related nuclear functions of human Pat1b, the P-body mRNA decay factor. (PubMed id 22090346)1, 2 Marnef A.... Standart N. (Mol. Biol. Cell 2012)
    3. The human Pat1b protein: a novel mRNA deadenylation factor identified by a new immunoprecipitation technique. (PubMed id 20852261)1, 2 Totaro A....Achsel T. (Nucleic Acids Res. 2011)
    4. Human Pat1b connects deadenylation with mRNA decapping and controls the assembly of processing bodies. (PubMed id 20584987)1, 2 Ozgur S.... Stoecklin G. (Mol. Cell. Biol. 2010)
    5. The C-terminal alpha-alpha superhelix of Pat is required for mRNA decapping in metazoa. (PubMed id 20543818)1, 2 Braun J.E.... Izaurralde E. (EMBO J. 2010)
    6. Distinct functions of maternal and somatic Pat1 protein paralogs. (PubMed id 20826699)1, 2 Marnef A.... Standart N. (RNA 2010)
    7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    8. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    9. Role of Rck-Pat1b binding in assembly of processing-bodies. (PubMed id 23535175)1 Ozgur S. and Stoecklin G. (RNA Biol 2013)
    10. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 219988 HGNC: 26721 AceView: FLJ36874 Ensembl:ENSG00000166889 euGenes: HUgn219988
    ECgene: PATL1 Kegg: 219988 H-InvDB: PATL1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for PATL1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for PATL1 gene:
    Search GeneIP for patents involving PATL1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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