Aliases for PASD1 Gene
External Ids for PASD1 Gene
Previous GeneCards Identifiers for PASD1 Gene
This gene encodes a protein that is thought to function as a transcription factor. The protein is a cancer-associated antigen that can stimulate autologous T-cell responses, and it is therefore considered to be a potential immunotherapeutic target for the treatment of various hematopoietic malignancies, including diffuse large B-cell lymphoma. [provided by RefSeq, May 2010]
GeneCards Summary for PASD1 Gene
PASD1 (PAS Domain Containing 1) is a Protein Coding gene. Diseases associated with PASD1 include diffuse large b-cell lymphoma. GO annotations related to this gene include signal transducer activity.
UniProtKB/Swiss-Prot for PASD1 Gene
Functions as a suppressor of the biological clock that drives the daily circadian rhythms of cells throughout the body (PubMed:25936801). Acts as a nuclear repressor of the CLOCK-ARNTL/BMAL1 heterodimer-mediated transcriptional activation of the core clock components (PubMed:25936801). Inhibits circadian clock function in cancer cells, when overexpressed (PubMed:25936801).