Aliases for PARVA Gene
Aliases for PARVA Gene
External Ids for PARVA Gene
- HGNC: 14652
- Entrez Gene: 55742
- Ensembl: ENSG00000197702
- OMIM: 608120
- UniProtKB: Q9NVD7
Previous HGNC Symbols for PARVA Gene
- MXRA2
Previous GeneCards Identifiers for PARVA Gene
- GC11P013670
- GC11P013148
- GC11P012438
- GC11P012363
- GC11P012355
- GC11P012075
Summaries for PARVA Gene
-
This gene encodes a member of the parvin family of actin-binding proteins. Parvins are associated with focal contacts and contain calponin homology domains that bind to actin filaments. The encoded protein is part of the integrin-linked kinase signaling complex and plays a role in cell adhesion, motility and survival. [provided by RefSeq, Dec 2010]
GeneCards Summary for PARVA Gene
PARVA (Parvin Alpha) is a Protein Coding gene. Diseases associated with PARVA include Metagonimiasis and Adiaspiromycosis. Among its related pathways are Primary Focal Segmental Glomerulosclerosis FSGS and ERK Signaling. Gene Ontology (GO) annotations related to this gene include actin binding. An important paralog of this gene is PARVB.
UniProtKB/Swiss-Prot for PARVA Gene
-
Plays a role in sarcomere organization and in smooth muscle cell contraction. Required for normal development of the embryonic cardiovascular system, and for normal septation of the heart outflow tract. Plays a role in sprouting angiogenesis and is required for normal adhesion of vascular smooth muscle cells to endothelial cells during blood vessel development (By similarity). Plays a role in the reorganization of the actin cytoskeleton, formation of lamellipodia and ciliogenesis. Plays a role in the establishement of cell polarity, cell adhesion, cell spreading, and directed cell migration.
Additional gene information for PARVA Gene
- Monarch Initiative
- Search for PARVA at DataMed
- Search for PARVA at HumanCyc
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PARVA Gene
Genomics for PARVA Gene
GeneHancer (GH) Regulatory Elements for PARVA Gene
Regulatory Element Products
Genomic Locations for PARVA Gene
- chr11:12,376,441-12,535,356
- (GRCh38/hg38)
- Size:
- 158,916 bases
- Orientation:
- Plus strand
- chr11:12,398,732-12,556,903
- (GRCh37/hg19)
Genomic View for PARVA Gene
- Cytogenetic band:
-
- 11p15.3 by Ensembl
- 11p15.3 by Entrez Gene
- 11p15.3 by HGNC


RefSeq DNA sequence for PARVA Gene
Proteins for PARVA Gene
-
Protein details for PARVA Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9NVD7-PARVA_HUMAN
- Recommended name:
- Alpha-parvin
- Protein Accession:
- Q9NVD7
- Q96C85
- Q9HA48
Protein attributes for PARVA Gene
- Size:
- 372 amino acids
- Molecular mass:
- 42244 Da
- Quaternary structure:
-
- Interacts with TGFB1I1 (By similarity). Interacts with ILK, LIMS1 and PXN (via LD motifs). Interacts with ARHGAP31. Interacts with the actin cytoskeleton.
Three dimensional structures from OCA and Proteopedia for PARVA Gene
Protein Expression for PARVA Gene
Post-translational modifications for PARVA Gene
Other Protein References for PARVA Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- R&D Systems Antibodies for PARVA (alpha-Parvin)
- Cell Signaling Technology (CST) Antibodies for PARVA (PARVA)
-
Custom Antibody ServicesOriGene Antibodies for PARVA
- AP53170PU-N
- TA505989
- CF505989
- TA505991
- CF505991
- TA505992
- CF505992
- TA505993
- CF505993
- TA505997
- CF505997
- TA505998
- CF505998
- TA505999
- CF505999
- TA506000
- CF506000
- TA506001
- CF506001
- TA506002
- CF506002
- TA506003
- CF506003
- TA506025
- CF506025
- TA600342
- TA600343
- TA600344
- TA600345
- TA600346
- TA600347
- TA600348
- TA600349
- TA700342
- TA700343
- TA505993S
- Novus Biologicals Antibodies for PARVA
-
Abcam antibodies for PARVA
- Invitrogen Antibodies for PARVA
- GeneTex PARVA antibody for PARVA
- Sino Biological Antibodies for PARVA
Protein Products
-
OriGene Purified Proteins for PARVA
- Search Origene for MassSpec and Protein Over-expression Lysates for PARVA
- Origene Custom Protein Services for PARVA
- Sino Biological Recombinant Proteins for PARVA
- Browse Sino Biological Cell Lysates
- ProSpec Recombinant Proteins for PARVA
- Search GeneTex for Proteins for PARVA
-
ProSci Proteins for PARVA
-
Abcam proteins for PARVA
Assay Products
No data available for DME Specific Peptides for PARVA Gene
Domains & Families for PARVA Gene
Gene Families for PARVA Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
- Predicted membrane proteins
Protein Domains for PARVA Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for PARVA Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q9NVD7- Family:
-
- Belongs to the parvin family.
Function for PARVA Gene
Molecular function for PARVA Gene
- UniProtKB/Swiss-Prot Function:
- Plays a role in sarcomere organization and in smooth muscle cell contraction. Required for normal development of the embryonic cardiovascular system, and for normal septation of the heart outflow tract. Plays a role in sprouting angiogenesis and is required for normal adhesion of vascular smooth muscle cells to endothelial cells during blood vessel development (By similarity). Plays a role in the reorganization of the actin cytoskeleton, formation of lamellipodia and ciliogenesis. Plays a role in the establishement of cell polarity, cell adhesion, cell spreading, and directed cell migration.
Phenotypes From GWAS Catalog for PARVA Gene
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0003779 | actin binding | IEA | -- |
GO:0005515 | protein binding | IPI | 12432066 |
GO:0045296 | cadherin binding | IDA | 25468996 |
Phenotypes for PARVA Gene
- MGI mutant phenotypes for PARVA:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for PARVA:
-
- Increased vaccinia virus (VACV) infection
- Increased shRNA abundance (Z-score > 2)
- Decreased shRNA abundance (Z-score < -2)
- Decreased HIV-LTR-beta-galactosidase protein expression
- Decreased focal adhesion (FA) area, decreased FA length, decreased FA mean intensity, increased number of small and round FAs, increased FA abundance
- Decreased cell migration
- Decreased Tat-dependent HIV-LTR-beta-galactosidase protein expression
- Increased cell migration
- Increased cilium length after serum starvation
- Increased cilium length
Animal Models for PARVA Gene
- MGI Knock Outs for PARVA:
-
- Parva tm1Ref
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for PARVA
-
-
ViGene Biosciences lentiviral particle packaged cDNA for PARVA gene
-
ViGene Biosciences ready-to-package AAV shRNAs for PARVA gene
- Search ViGene Biosciences for PARVA
CRISPR Products
-
OriGene CRISPR knockouts for PARVA
- genomics-online: gRNA clones - Search results for 109 available Parvin alpha gene related products
- Overview of 109 available Parvin alpha gene related products
- Applied Biological Materials CRISPR for PARVA
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for PARVA
- GenScript: Design CRISPR guide RNA sequences for PARVA
miRNA for PARVA Gene
- miRTarBase miRNAs that target PARVA
-
- hsa-mir-1-3p (MIRT023795)
- hsa-mir-633 (MIRT497651)
- hsa-mir-3160-5p (MIRT497652)
- hsa-mir-631 (MIRT497653)
- hsa-mir-3661 (MIRT497654)
- hsa-mir-1322 (MIRT535489)
- hsa-mir-1272 (MIRT535490)
- hsa-mir-660-3p (MIRT667055)
- hsa-mir-5193 (MIRT667056)
- hsa-mir-4485-5p (MIRT667057)
- hsa-mir-483-3p (MIRT667058)
- hsa-mir-5195-5p (MIRT667059)
- hsa-mir-24-1-5p (MIRT739208)
- hsa-mir-24-2-5p (MIRT739215)
- hsa-mir-888-5p (MIRT760423)
miRNA Products
- Search ViGene Biosciences for PARVA
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for PARVA
- Browse OriGene Inhibitory RNA Products For PARVA
- genomics-online: shRNA clones - Search results for 109 available Parvin alpha gene related products
- Overview of 109 available Parvin alpha gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for PARVA gene
Clone Products
- Sino Biological Human cDNA Clone for PARVA
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for PARVA
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for PARVA
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for PARVA
- genomics-online: cdna clones - Search results for 109 available Parvin alpha gene related products
- Overview of 109 available Parvin alpha gene related products
- orf clones - Search results for 109 available Parvin alpha gene related products
- Overview of 109 available Parvin alpha gene related products
- Applied Biological Materials Clones for PARVA
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for PARVA
-
ViGene Biosciences adenoviral particle packaged cDNA for PARVA gene
-
ViGene Biosciences lentiviral particle packaged cDNA for PARVA gene
-
ViGene Biosciences ready-to-package AAV shRNAs for PARVA gene
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for PARVA Gene
Localization for PARVA Gene
Subcellular locations from UniProtKB/Swiss-Prot for PARVA Gene
- Cell junction, focal adhesion. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cytoplasm, myofibril, sarcomere, Z line. Note=Constituent of focal adhesions. Associates with the actin cytoskeleton.
- Actin filaments (3)
- Cytosol (3)
- Focal adhesion sites (3)
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005634 | nucleus | IEA | -- |
GO:0005737 | cytoplasm | IEA | -- |
GO:0005829 | cytosol | TAS,IDA | -- |
GO:0005856 | cytoskeleton | IEA | -- |
GO:0005886 | plasma membrane | IEA | -- |
Pathways & Interactions for PARVA Gene
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Cell junction organization | ||
2 | Focal Adhesion |
.62
|
|
3 | Adhesion |
-
|
|
4 | Cytoskeletal Signaling | ||
5 | ERK Signaling |
.49
|
Pathways by source for PARVA Gene
2 Cell Signaling Technology pathways for PARVA Gene
1 BioSystems pathway for PARVA Gene
1 KEGG pathway for PARVA Gene
1 GeneGo (Thomson Reuters) pathway for PARVA Gene
2 Qiagen pathways for PARVA Gene
Interacting Proteins for PARVA Gene
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0002040 | sprouting angiogenesis | ISS | -- |
GO:0003148 | outflow tract septum morphogenesis | IEA,ISS | -- |
GO:0007155 | cell adhesion | IEA | -- |
GO:0007163 | establishment or maintenance of cell polarity | ISS,IEA | -- |
GO:0008360 | regulation of cell shape | IEA | -- |
No data available for SIGNOR curated interactions for PARVA Gene
Transcripts for PARVA Gene
mRNA/cDNA for PARVA Gene
- (2) REFSEQ mRNAs :
- (11) Additional mRNA sequences :
- (331) Selected AceView cDNA sequences:
- (6) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
-
OriGene CRISPR knockouts for PARVA
- genomics-online: gRNA clones - Search results for 109 available Parvin alpha gene related products
- Overview of 109 available Parvin alpha gene related products
- Applied Biological Materials CRISPR for PARVA
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for PARVA
- GenScript: Design CRISPR guide RNA sequences for PARVA
miRNA Products
- Search ViGene Biosciences for PARVA
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for PARVA
- Browse OriGene Inhibitory RNA Products For PARVA
- genomics-online: shRNA clones - Search results for 109 available Parvin alpha gene related products
- Overview of 109 available Parvin alpha gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for PARVA gene
Clone Products
- Sino Biological Human cDNA Clone for PARVA
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for PARVA
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for PARVA
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for PARVA
- genomics-online: cdna clones - Search results for 109 available Parvin alpha gene related products
- Overview of 109 available Parvin alpha gene related products
- orf clones - Search results for 109 available Parvin alpha gene related products
- Overview of 109 available Parvin alpha gene related products
- Applied Biological Materials Clones for PARVA
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
ExUns: | 1 | ^ | 2a | · | 2b | · | 2c | · | 2d | · | 2e | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7a | · | 7b | · | 7c | ^ | 8a | · | 8b | ^ | 9a | · | 9b | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||
SP2: | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
SP3: | |||||||||||||||||||||||||||||||||||||||||||||||
SP4: | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||
SP5: | - | - | |||||||||||||||||||||||||||||||||||||||||||||
SP6: | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
SP7: | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||
SP8: | - |
Expression for PARVA Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Endothelium (Cardiovascular System)
- Extraembryonic Angioblasts Extraembryonic Capillary Plexus
- Endothelial cells (family)
- Human umbilical vein endothelial cells (HUVEC)
- Brain (Nervous System)
- Lung (Respiratory System)
-
Testis (Reproductive System)
- Testicular Interstitial Cells Testis Interstitium
-
Extraembryonic Mesoderm (Extraembryonic Tissues)
- Extraembryonic Angioblasts Extraembryonic Capillary Plexus
-
Epidermis (Integumentary System)
- Basal Keratinocytes Embryonic Epidermis
-
Epithelial Cells
- Basal Keratinocytes Embryonic Epidermis
-
Hair
- Basal Keratinocytes Embryonic Epidermis
- Neural Tube (Nervous System)
- Kidney (Urinary System)
- NULL (Uncategorized)
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for PARVA Gene
NURSA nuclear receptor signaling pathways regulating expression of PARVA Gene:
PARVASOURCE GeneReport for Unigene cluster for PARVA Gene:
Hs.432914mRNA Expression by UniProt/SwissProt for PARVA Gene:
Q9NVD7-PARVA_HUMANEvidence on tissue expression from TISSUES for PARVA Gene
- Nervous system(4.7)
- Liver(4.2)
- Intestine(2.8)
- Skin(2.8)
- Lung(2.7)
- Muscle(2.3)
Primer Products
-
OriGene qPCR primer pairs for PARVA
No data available for mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for PARVA Gene
Orthologs for PARVA Gene
This gene was present in the common ancestor of animals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
chimpanzee (Pan troglodytes) |
Mammalia | PARVA 33 34 |
|
||
oppossum (Monodelphis domestica) |
Mammalia | PARVA 34 |
|
OneToOne | |
cow (Bos Taurus) |
Mammalia | PARVA 34 33 |
|
OneToOne | |
dog (Canis familiaris) |
Mammalia | PARVA 34 33 |
|
OneToOne | |
rat (Rattus norvegicus) |
Mammalia | Parva 33 |
|
||
mouse (Mus musculus) |
Mammalia | Parva 33 16 34 |
|
||
platypus (Ornithorhynchus anatinus) |
Mammalia | PARVA 34 |
|
OneToOne | |
chicken (Gallus gallus) |
Aves | PARVA 33 34 |
|
||
lizard (Anolis carolinensis) |
Reptilia | PARVA 34 |
|
OneToOne | |
tropical clawed frog (Silurana tropicalis) |
Amphibia | parva 33 |
|
||
zebrafish (Danio rerio) |
Actinopterygii | parvab 34 34 |
|
OneToMany | |
parvaa 33 34 |
|
||||
rainbow trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.703 33 |
|
||
fruit fly (Drosophila melanogaster) |
Insecta | CG32528 34 |
|
OneToMany | |
worm (Caenorhabditis elegans) |
Secernentea | pat-6 34 33 35 |
|
OneToMany | |
sea squirt (Ciona savignyi) |
Ascidiacea | -- 34 |
|
OneToMany |
- Species where no ortholog for PARVA was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for PARVA Gene
(2) SIMAP similar genes for PARVA Gene using alignment to 5 proteins:
Variants for PARVA Gene
SNP ID | Clin | Chr 11 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs1000007411 | -- | 12,406,959(+) | C/T | intron_variant | |
rs1000037270 | -- | 12,518,086(+) | G/A | intron_variant | |
rs1000058440 | -- | 12,499,261(+) | C/T | intron_variant | |
rs1000097388 | -- | 12,503,001(+) | T/C | intron_variant | |
rs1000106818 | -- | 12,456,127(+) | C/T | intron_variant |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
dgv1059n100 | CNV | gain | 25217958 |
dgv1657n54 | CNV | loss | 21841781 |
dgv589n106 | CNV | deletion | 24896259 |
esv2411772 | CNV | deletion | 18987734 |
esv26204 | CNV | loss | 19812545 |
esv2624026 | CNV | deletion | 19546169 |
esv2670255 | CNV | deletion | 23128226 |
esv3547336 | CNV | deletion | 23714750 |
esv3579371 | CNV | loss | 25503493 |
esv3579373 | CNV | loss | 25503493 |
esv3625390 | CNV | gain | 21293372 |
esv3625391 | CNV | gain | 21293372 |
esv3625392 | CNV | loss | 21293372 |
esv3625393 | CNV | gain | 21293372 |
esv3625395 | CNV | gain | 21293372 |
esv3625396 | CNV | loss | 21293372 |
esv3625397 | CNV | loss | 21293372 |
esv3625398 | CNV | loss | 21293372 |
esv3891929 | CNV | loss | 25118596 |
nsv1050553 | CNV | gain | 25217958 |
nsv1070433 | CNV | deletion | 25765185 |
nsv1144535 | CNV | deletion | 24896259 |
nsv1145500 | CNV | deletion | 24896259 |
nsv477778 | CNV | novel sequence insertion | 20440878 |
nsv483000 | CNV | loss | 15286789 |
nsv519326 | CNV | loss | 19592680 |
nsv524625 | CNV | loss | 19592680 |
Additional Variant Information for PARVA Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- PARVA
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for PARVA Gene
Disorders for PARVA Gene
Disorder | Aliases | PubMed IDs |
---|---|---|
metagonimiasis |
|
|
adiaspiromycosis |
|
|
breast giant fibroadenoma |
|
|
vein disease |
|
|
Additional Disease Information for PARVA
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for PARVA Gene
Publications for PARVA Gene
- Parvin, a 42 kDa focal adhesion protein, related to the alpha-actinin superfamily. (PMID: 11171322) Olski TM … Korenbaum E (Journal of cell science 2001) 2 3 4 22 58
- The pseudoactive site of ILK is essential for its binding to alpha-Parvin and localization to focal adhesions. (PMID: 20005845) Fukuda K … Qin J (Molecular cell 2009) 3 4 22 58
- The structure of alpha-parvin CH2-paxillin LD1 complex reveals a novel modular recognition for focal adhesion assembly. (PMID: 18508764) Wang X … Qin J (The Journal of biological chemistry 2008) 3 4 22 58
- Structural analysis of the interactions between paxillin LD motifs and alpha-parvin. (PMID: 18940607) Lorenz S … Hoellerer MK (Structure (London, England : 1993) 2008) 3 4 22 58
- CdGAP associates with actopaxin to regulate integrin-dependent changes in cell morphology and motility. (PMID: 16860736) LaLonde DP … Turner CE (Current biology : CB 2006) 3 4 22 58
Products for PARVA Gene
- R&D Systems Antibodies for PARVA (alpha-Parvin)
- Browse R&D Systems for Human Recombinant Proteins
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- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
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- Custom Antibody ServicesOriGene Antibodies for PARVA
- AP53170PU-N
- TA505989
- CF505989
- TA505991
- CF505991
- TA505992
- CF505992
- TA505993
- CF505993
- TA505997
- CF505997
- TA505998
- CF505998
- TA505999
- CF505999
- TA506000
- CF506000
- TA506001
- CF506001
- TA506002
- CF506002
- TA506003
- CF506003
- TA506025
- CF506025
- TA600342
- TA600343
- TA600344
- TA600345
- TA600346
- TA600347
- TA600348
- TA600349
- TA700342
- TA700343
- TA505993S
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for PARVA
- Search Origene for MassSpec and Protein Over-expression Lysates for PARVA
- Origene Custom Protein Services for PARVA
- Origene shrna, sirna, and RNAi products in human, mouse, rat for PARVA
- Browse OriGene Inhibitory RNA Products For PARVA
- OriGene qPCR primer pairs for PARVA
- OriGene CRISPR knockouts for PARVA
- OriGene ORF clones in human for PARVA
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For PARVA
- GenScript: Next-day shipping of latest version cDNA ORF clones for PARVA in any vector
- GenScript Custom Purified and Recombinant Proteins Services for PARVA
- GenScript Custom Assay Services for PARVA
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- GenScript: Design CRISPR guide RNA sequences for PARVA
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
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- Gene Mutant Library, Variants up to 10^11
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- Cell Signaling Technology (CST) Antibodies for PARVA (PARVA)
- Search for Antibodies & Assays
- Sino Biological Human cDNA Clone for PARVA
- Sino Biological Recombinant Proteins for PARVA
- Browse Sino Biological Cell Lysates
- Sino Biological Antibodies for PARVA
- Browse Sino Biological Assays
- Browse Sino Biological ELISA Kits
- Browse Sino Biological ELISA Pair Sets
- Browse Sino Biological CRO Services
- Browse Sino Biological Control Vectors
- Sino Biological Transfection Reagent
- Sino Biological Anti-His Tag Antibody
- Novus Biologicals Antibodies for PARVA
- Novus Biologicals proteins and lysates for PARVA
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Abcam antibodies for PARVA
- Abcam proteins for PARVA
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
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- Browse ELISA Kits
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- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
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- ProSpec Recombinant Proteins for PARVA
- Browse Antibodies at Cloud-Clone Corp.
- Browse Proteins at Cloud-Clone Corp.
- Browse Assay Kits at Cloud-Clone Corp.
- Browse Knockouts at Cloud-Clone Corp.
- Browse Knockins at Cloud-Clone Corp.
- Cloud-Clone Corp. disease models service
- Browse cDNA clones at Cloud-Clone Corp.
- Browse primers at Cloud-Clone Corp.
- Cloud-Clone Corp. primary cells service
- Invitrogen Antibodies for PARVA
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Cyagen custom Knockout/knockin (KOKI) mouse models for PARVA
- VectorBuilder custom plasmid, inducible vectors for PARVA
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for PARVA
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for PARVA
- antibodies-online: Search results for 93 available Parvin alpha Antibodies ranked by validation data
- Compare Top Parvin alpha Antibodies
- antibodies-online: Search results for available Parvin alpha related products ranked by validation data
- antibodies-online: Search results for 11 available Parvin alpha Proteins ranked by validation data
- Compare Top Parvin alpha Proteins
- GeneTex PARVA antibody for PARVA
- Search GeneTex for Proteins for PARVA
- ViGene Biosciences adenoviral particle packaged cDNA for PARVA gene
- ViGene Biosciences lentiviral particle packaged cDNA for PARVA gene
- ViGene Biosciences ready-to-package AAV shRNAs for PARVA gene
- Search ViGene Biosciences for PARVA
- Browse Santa Cruz Biotechnology (SCBT) Antibodies
- Search Santa Cruz Biotechnology (SCBT) for PARVA siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for PARVA
- Search for PARVA Antibodies at ProSci
- Custom Antibody Services
- ProSci Proteins for PARVA
- Horizon Cell Lines for PARVA
- genomics-online: cdna clones - Search results for 109 available Parvin alpha gene related products
- Overview of 109 available Parvin alpha gene related products
- orf clones - Search results for 109 available Parvin alpha gene related products
- Overview of 109 available Parvin alpha gene related products
- genomics-online: gRNA clones - Search results for 109 available Parvin alpha gene related products
- Overview of 109 available Parvin alpha gene related products
- genomics-online: primer clones - Search results for 109 available Parvin alpha gene related products
- Overview of 109 available Parvin alpha gene related products
- genomics-online: shRNA clones - Search results for 109 available Parvin alpha gene related products
- Overview of 109 available Parvin alpha gene related products
Sources for PARVA Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew