Aliases for PARPBP Gene
External Ids for PARPBP Gene
Previous HGNC Symbols for PARPBP Gene
Previous GeneCards Identifiers for PARPBP Gene
GeneCards Summary for PARPBP Gene
PARPBP (PARP1 Binding Protein) is a Protein Coding gene.
UniProtKB/Swiss-Prot for PARPBP Gene
Required to suppress inappropriate homologous recombination, thereby playing a central role DNA repair and in the maintenance of genomic stability. Antagonizes homologous recombination by interfering with the formation of the RAD51-DNA homologous recombination structure. Binds single-strand DNA and poly(A) homopolymers. Positively regulate the poly(ADP-ribosyl)ation activity of PARP1; however such function may be indirect.