PARP8 Gene
protein-coding GIFtS: 50
GCID: GC05P049998
|
|
poly (ADP-ribose) polymerase family, member 8
| |
Aliases for PARP8 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Poly (ADP-Ribose) Polymerase Family, Member 81 2 | | EC 2.4.2.303 8 | | PART161 | | FLJ213081 | | ARTD162 3 | | Poly [ADP-Ribose] Polymerase 82 | | ADP-Ribosyltransferase Diphtheria Toxin-Like 162 3 | | PARP-83 |
Export aliases for PARP8 gene to outside databasesPrevious GC identifer: GC05P046926 |
Summaries for PARP8 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
summary
for PARP8: Poly (ADP-ribose) polymerase (PARP) catalyzes the post-translational modification of proteins by the addition of multiple ADP-ribose moieties. PARP transfers ADP-ribose from nicotinamide dinucleotide (NAD) to glu/asp residues on the substrate protein, and also polymerizes ADP-ribose to form long/branched chain polymers. PARP inhibitors are being developed for use in a number of pathologies including cancer, diabetes, stroke and cardiovascular disease. Gene Wiki entry for PARP8
|
Genomic Views for PARP8 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000005.9 NC_018916.1 NT_006713.15
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the PARP8 gene promoter: HEN1 AREB6 FOXJ2 (long isoform) Zic1 FOXO1a FOXJ2 Evi-1 FOXO1 Other transcription factors
Search SABiosciences Chromatin IP Primers for PARP8
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PARP8 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 5q11.1 Ensembl cytogenetic band: 5q11.1 HGNC cytogenetic band: 5q11.2PARP8 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 5 GeneLoc Exon Structure GeneLoc location for GC05P049998: view genomic region
(about GC identifiers)
Start:
|
49,961,733 bp from pter |
End:
|
50,142,356 bp from pter |
Size:
|
180,624 bases |
Orientation:
|
plus strand |
|
Proteins for PARP8 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: PARP8_HUMAN, Q8N3A8 (See
protein sequence)Recommended Name: Poly [ADP-ribose] polymerase 8 Size: 854 amino acids; 95871 Da
Sequence caution: Sequence=AAI05790.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-Asequence;
Secondary accessions: Q3KRB7 Q6DHZ1 Q9H754Alternative splicing: 2 isoforms: Q8N3A8-1 Q8N3A8-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for PARP8: NX_Q8N3A8
Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8N3A8 4/11 DME Specific Peptides for PARP8 (Q8N3A8) (see all 11)
PARP8 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001171526.1 NP_001171527.1 NP_078891.2 ENSEMBL proteins: ENSP00000422217 ENSP00000422183 ENSP00000421503 ENSP00000422288 ENSP00000426243 ENSP00000423133 ENSP00000281631 ENSP00000422355 ENSP00000427138 ENSP00000426679 ENSP00000424814 ENSP00000421708 ENSP00000424916 ENSP00000424485 ENSP00000423946 ENSP00000423997 ENSP00000440851 ENSP00000439022 Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005622 | intracellular |
IDA | -- |
PARP8 for ontologies About GeneDecksing
PARP8 Antibody Products: Assay Products for PARP8: |
Protein
Domains / Families for PARP8 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
PARP8 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q8N3A8ProtoNet protein and cluster: Q8N3A8 UniProtKB/Swiss-Prot: PARP8_HUMAN, Q8N3A8Similarity: Contains 1 PARP catalytic domain |
Function for PARP8 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: PARP8_HUMAN, Q8N3A8Catalytic activity: NAD(+) + (ADP-D-ribosyl)(n)-acceptor = nicotinamide + (ADP-D-ribosyl)(n+1)-acceptorEnzyme Number (IUBMB): EC 2.4.2.301 2
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PARP8 (see all 6) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PARP8 (see all 3) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): PARP8 (NM_024615) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for PARP8 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PARP8  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PARP8 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003950 | NAD+ ADP-ribosyltransferase activity |
IEA | -- |
PARP8 for ontologies About GeneDecksing
|
Pathways & Interactions for PARP8 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for PARP8
|
Drugs & Compounds for PARP8 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Compounds for PARP8 available from Tocris Bioscience About this table
1 HMDB Compound for PARP8 About this table
| Compound | Synonyms |
CAS
# | PubMed Ids |
|---|
| NAD | 3-Carbamoyl-1-D-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate (see all 28) | 53-84-9 | -- | Search CenterWatch for drugs/clinical trials and news about PARP8 
|
Transcripts for PARP8 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for PARP8 gene (3 alternative transcripts): NM_001178055.1 NM_001178056.1 NM_024615.3 Unigene Cluster for PARP8: Poly (ADP-ribose) polymerase family, member 8 Hs.369581 [show with all ESTs]Unigene Representative Sequence: NM_00117805518/24 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 24): ENST00000503790 ENST00000505697 ENST00000511363 ENST00000507812 ENST00000503888 ENST00000510303 ENST00000502524 ENST00000515175 ENST00000513414 ENST00000510040 ENST00000281631(uc003joo.3 uc003jop.3) ENST00000506369 ENST00000513738 ENST00000503665 ENST00000503707 ENST00000514067 ENST00000503046 ENST00000503193
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PARP8 (see all 6) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PARP8 (see all 3) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): PARP8 (NM_024615) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for PARP8 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PARP8  |
Additional cDNA sequence: AK024961.1 AK225188.1 AK289369.1 AK298680.1 AK314466.1 AL834477.1 BC037386.1 BC058033.1 BC075801.1 BC105789.1 13 DOTS entries: DT.112097 DT.40117588 DT.120877005 DT.306470 DT.95336399 DT.304722 DT.100826921 DT.40210965 DT.306469 DT.120877033 DT.40196229 DT.95106701 DT.95191873 24/91 AceView cDNA sequences (see all 91): BP871383 AI016244 BQ421166 AA039597 AL834477 R80933 NM_024615 CB070410 AW131872 BU785518 C01605 AI625670 AK024961 AA039956 AA977676 AA367044 AI201016 BC075801 AI168822 AA743485 AV713749 AA910504 AA826433 AA039596 GeneLoc Exon Structure
5 Alternative Splicing Database (ASD) splice patterns (SP) for PARP8 About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 | ^ | 8a | · | 8b | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20 | ^ | 21 | ^ | 22 | ^ | 23 | ^ | |
| SP1: | |   | |   | - |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | - |   | - |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
| ExUns: | 24 | ^ | 25 | ^ | 26a | · | 26b | ^ | 27 | |
| SP1: | |   | |   | - |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | - |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for PARP8
|
Expression for PARP8 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| PARP8 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: ATTCGAAAGC
About this image See PARP8 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for PARP8
SOURCE GeneReport for Unigene cluster: Hs.369581 SABiosciences Custom PCR Arrays for PARP8
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PARP8 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat PARP8 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PARP8 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PARP8 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PARP8 |
Orthologs for PARP8 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for PARP8 gene from 4/11 species (see all 11) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
mouse (Mus musculus) |
Mammalia |
Parp81 , 5 |
poly (ADP-ribose) polymerase family, member 81, 5 |
89.24(n)1 96.36(a)1 |
  |
13 (65.32 cM)5 525521 NM_001081009.11 NP_001074478.11 1168548245 |
chicken (Gallus gallus) |
Aves |
PARP81 |
poly (ADP-ribose) polymerase family, member 8 |
85.19(n) 93.2(a) |
  |
427198 XM_424786.3 XP_424786.3 |
lizard (Anolis carolinensis) |
Reptilia |
PARP86 |
-- |
89(a) |
1 ↔ 1 |
2(4704871-4789314) |
zebrafish (Danio rerio) |
Actinopterygii |
Dr.258372 |
Transcribed sequence with weak similarity to protein more |
78.03(n) |
  |
CD604769.1 |
ENSEMBL Gene Tree for PARP8 (if available) TreeFam Gene Tree for PARP8 (if available)  |
Paralogs for PARP8 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for PARP8 gene
- PARP62
3 SIMAP similar genes for PARP8 using alignment to 16 protein entries: PARP8_HUMAN (see all proteins):PARP6 PARP-6 CNOT2
PARP8 for paralogs About GeneDecksing
4 Pseudogenes.org Pseudogenes for PARP8 PGOHUM00000251074 PGOHUM00000251078 PGOHUM00000251083 PGOHUM00000251133
|
Genomic Variants for PARP8 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 5 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for PARP8 (49961733 - 50142356 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 10 variations for PARP8 10 CNVs: 3554 93041 53072 10115 69062 93044 93042 80916 59267 93043  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PARP8 |
|
Disorders
/ Diseases for PARP8 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
PARP8 for disorders About GeneDecksing
2 diseases for PARP8: About MalaCardsroot resorption diphtheria 1 disease from the University of Copenhagen DISEASES database for PARP8:Root resorption Export disorders for PARP8 gene to outside databases
|
Publications for PARP8 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for PARP8 gene, integrated from 9 sources (see all 15): (articles sorted by number of sources associating them with PARP8) | |  | Utopia: connect your pdf to the dynamic world of online information |
- The PARP superfamily. (PubMed id 15273990)1, 3 Ame J.C....de Murcia G. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Genetic variants on chromosome 1q41 influence ocular a xial length and high myopia. (PubMed id 22685421)1 Fan Q....Saw S.M. (2012)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
- Toward a unified nomenclature for mammalian ADP- ribosyltransferases. (PubMed id 20106667)2 Hottiger M.O.... Koch-Nolte F. (2010)
- The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
- The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)2 Sjoeblom T.... Velculescu V.E. (2006)
- The LIFEdb database in 2006. (PubMed id 16381901)1 Mehrle A....Wiemann S. (2006)
- From ORFeome to biology: a functional genomics pipeline. (PubMed id 15489336)1 Wiemann S....Poustka A. (2004)
|
External Searches for PARP8 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing PARP8 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing PARP8 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing PARP8 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for PARP8 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for PARP8 gene: Search GeneIP for patents involving PARP8
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for PARP8 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
|
 | |
 | |
 |
| | | | Browse OriGene Antibodies | | OriGene shRNA RFP for PARP8 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for PARP8 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PARP8 | | OriGene Protein Over-expression Lysate for PARP8 | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for PARP8 | | OriGene 3'-UTR Clone for PARP8 | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PARP8 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PARP8 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for PARP8 | | OriGene Custom Protein Services for PARP8 | | OriGene Custom Immunoassay Development | | |
| |  |
 |
| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat PARP8 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PARP8 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PARP8 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat PARP8 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PARP8 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PARP8 |
| |
 |  |  |  | |
| | | Tocris compounds for PARP8 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | PARP8 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PARP8 |
|  |  |  | | | ThermoFisher Antibodies for PARP8 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PARP8 |
|
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