Aliases for PARP15 Gene
External Ids for PARP15 Gene
Previous GeneCards Identifiers for PARP15 Gene
PARP15 is a macrodomain-containing transcriptional repressor with poly(ADP-ribose) polymerase activity (Aguiar et al., 2005 [PubMed 16061477]).[supplied by OMIM, May 2008]
GeneCards Summary for PARP15 Gene
PARP15 (Poly (ADP-Ribose) Polymerase Family, Member 15) is a Protein Coding gene. Diseases associated with PARP15 include urethral intrinsic sphincter deficiency. GO annotations related to this gene include NAD+ ADP-ribosyltransferase activity. An important paralog of this gene is PARP14.
UniProtKB/Swiss-Prot for PARP15 Gene
Transcriptional repressor. Has ADP-ribosyltransferase activity.
Poly (ADP-ribose) polymerase (PARP) catalyzes the post-translational modification of proteins by the addition of multiple ADP-ribose moieties. PARP transfers ADP-ribose from nicotinamide dinucleotide (NAD) to Glu/Asp residues on the substrate protein.