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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

PARD6G Gene

protein-coding GIFtS: 53
GCID: GC18M077915

par-6 partitioning defective 6 homolog gamma (C. elegans)

(Previous names: par-6 (partitioning defective 6, C.elegans) homolog gamma...)

Search for PARD6G
in

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Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Par-6 Partitioning Defective 6 Homolog Gamma (C. Elegans)¹ ²		PAR-6 Gamma Protein²
PAR-6G¹ ²		Partitioning Defective 6 Homolog Gamma²
PAR6gamma¹ ²		PAR6G³
PAR6D² ³		PAR-6 Gamma³
Par-6 (Partitioning Defective 6, C.Elegans) Homolog Gamma¹

External Ids:	HGNC: 16076¹	Entrez Gene: 84552²	Ensembl: ENSG00000178184⁷	OMIM: 608976⁵	UniProtKB: Q9BYG4³

Export aliases for PARD6G gene to outside databases

Previous GC identifers: GC18M077432 GC18M077971 GC18M077652 GC18M076016 GC18M076014 GC18M075999 GC18M074536

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: PAR6G_HUMAN, Q9BYG4

Function: Adapter protein involved in asymmetrical cell division and cell polarization processes. May play a role in

the formation of epithelial tight junctions. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical

protein kinase C proteins (By similarity)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000018.9 NC_018929.1 NT_025028.14

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the PARD6G gene promoter:
p53 Brachyury AP-2gamma POU3F2 Nkx5-1 E47 CREB AP-2beta Hand1 AP-2alphaA
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: PARD6G promoter sequence

Search SABiosciences Chromatin IP Primers for PARD6G

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PARD6G

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 18q23 Ensembl cytogenetic band: 18q23 HGNC cytogenetic band: 18q23

PARD6G Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PARD6G gene location

GeneLoc information about chromosome 18 GeneLoc Exon Structure

GeneLoc location for GC18M077915: view genomic region (about GC identifiers)

Start:	77,915,115 bp from pter	End:	78,005,429 bp from pter
Size:	90,315 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: PAR6G_HUMAN, Q9BYG4 (See protein sequence)

Recommended Name: Partitioning defective 6 homolog gamma

Size: 376 amino acids; 40883 Da

Subunit: Interacts with PARD3 (Probable). Interacts with GTP-bound forms of CDC42, ARHQ/TC10 and RAC1. Interacts with

the N-terminal part of PRKCI and PRKCZ

Subcellular location: Cytoplasm. Cell membrane (By similarity). Cell junction, tight junction (By similarity)

Explore the universe of human proteins at neXtProt for PARD6G: NX_Q9BYG4

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q9BYG4

PARD6G Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_115899.1

ENSEMBL proteins:

ENSP00000343144 ENSP00000468735 ENSP00000466076

Reactome Protein details: Q9BYG4
Human Recombinant Protein Products for PARD6G:

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	Browse Proteins at Uscn

Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005829	cytosol	TAS	--
GO:0005886	plasma membrane	TAS	--
GO:0005923	tight junction	IEA	--
GO:0043234	protein complex	IEA	--

PARD6G for ontologies About GeneDecksing

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Assay Products for PARD6G:

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	Browse ELISAs and CLIAs at Uscn

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

PARD6G for domains About GeneDecksing

2 InterPro domains/families:

IPR000270 OPR_PB1

IPR001478 PDZ

Graphical View of Domain Structure for InterPro Entry Q9BYG4

ProtoNet protein and cluster: Q9BYG4

2 Blocks protein families:

IPB000270 Octicosapeptide/Phox/Bem1p

IPB001478 PDZ/DHR/GLGF domain

UniProtKB/Swiss-Prot: PAR6G_HUMAN, Q9BYG4

Domain: The pseudo-CRIB domain together with the PDZ domain is required for the interaction with Rho small GTPases (By

similarity)

Similarity: Belongs to the PAR6 family

Similarity: Contains 1 OPR domain

Similarity: Contains 1 PDZ (DHR) domain

Similarity: Contains 1 pseudo-CRIB domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: PAR6G_HUMAN, Q9BYG4

Function: Adapter protein involved in asymmetrical cell division and cell polarization processes. May play a role in

the formation of epithelial tight junctions. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical

protein kinase C proteins (By similarity)

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005515	protein binding	IPI	14676191

PARD6G for ontologies About GeneDecksing

Animal Models:

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for PARD6G

miRNA Products:		OriGene 3'-UTR Clone: PARD6G Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat PARD6G
		8/20 QIAGEN miScript miRNA Assays for microRNAs that regulate PARD6G (see all 20):
		hsa-miR-320a hsa-miR-148b* hsa-miR-3942-5p hsa-miR-410 hsa-miR-133a hsa-miR-761 hsa-miR-3163 hsa-miR-634

		Browse SwitchGear 3'UTR luciferase reporter plasmids

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		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PARD6G (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PARD6G OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PARD6G

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

G-protein signaling_RAC1 in cellular process

	G-protein signaling_RAC1 in cellular process	1.00			Cytoskeleton remodeling_CDC42 in cellular processes	0.37
	G-protein signaling RAC1 in cellular process	1.00			Cytoskeleton remodeling CDC42 in cellular processes	0.37

Cell-cell junction organization

	Cell-cell junction organization	1.00			Tight junction interactions	0.49
	Cell junction organization	0.69			Cell-Cell communication	0.45

Development_A2B receptor- action via G-protein alpha s

Development A2A receptor signaling

0.43

Development_A2A receptor signaling

0.43

Tight junction

Tight junction

1.00

Endocytosis

Endocytosis

1.00

Pathway sources
See GeneCards unified pathways
Show all pathways

3 EMD Millipore Pathways for PARD6G

	G-protein signaling RAC1 in cellular process
	Cytoskeleton remodeling CDC42 in cellular processes
	Development A2A receptor signaling

3 GeneGo (Thomson Reuters) Pathways for PARD6G

	Development A2A receptor signaling
	G-protein signaling RAC1 in cellular process
	Cytoskeleton remodeling CDC42 in cellular processes

4 Reactome Pathways for PARD6G

	Tight junction interactions
	Cell junction organization
	Cell-Cell communication
	Cell-cell junction organization

2 Kegg Pathways (Kegg details for PARD6G):

	Endocytosis
	Tight junction

PARD6G for pathways About GeneDecksing

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for PARD6G

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

5/27 Interacting proteins for PARD6G (Q9BYG4^{1, 2, 3} ENSP00000343144⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 27)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
PARD3	Q8TEW0¹^,³, ENSP00000363921⁴	EBI-295417,EBI-1221123 I2D: score=4 STRING: ENSP00000363921
PRKCZ	Q05513²^,³, ENSP00000367830⁴	MINT-4085549 I2D: score=4 STRING: ENSP00000367830
MARK4	Q96L34¹^,³, ENSP00000300843⁴	EBI-295417,EBI-302319 I2D: score=1 STRING: ENSP00000300843
CDH5	P33151²^,³, ENSP00000344115⁴	MINT-4085562 I2D: score=1 STRING: ENSP00000344115
CDC42	P60953¹^,³, ENSP00000314458⁴	EBI-295417,EBI-81752 I2D: score=6 STRING: ENSP00000314458

About this table

Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0007049	cell cycle	IEA	--
GO:0034329	cell junction assembly	TAS	--
GO:0045216	cell-cell junction organization	TAS	--
GO:0051301	cell division	IEA	--
GO:0070830	tight junction assembly	TAS	--

PARD6G for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for PARD6G

1 HMDB Compound for PARD6G About this table

Compound	Synonyms	CAS #	PubMed Ids
Guanosine triphosphate	5'-GTP (see all 10)	86-01-1	--

Search CenterWatch for drugs/clinical trials and news about PARD6G / PAR6G

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for PARD6G gene:

NM_032510.3

Unigene Cluster for PARD6G:

Par-6 partitioning defective 6 homolog gamma (C. elegans)

Hs.654920 [show with all ESTs]

Unigene Representative Sequence: NM_032510

3 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000353265(uc002lny.3 uc010xfp.2) ENST00000470488 ENST00000463384

miRNA Products:		OriGene 3'-UTR Clone: PARD6G Browse OriGene MicroRNA Expression Plasmids
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		8/20 QIAGEN miScript miRNA Assays for microRNAs that regulate PARD6G (see all 20):
		hsa-miR-320a hsa-miR-148b* hsa-miR-3942-5p hsa-miR-410 hsa-miR-133a hsa-miR-761 hsa-miR-3163 hsa-miR-634

		Browse SwitchGear 3'UTR luciferase reporter plasmids

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Additional cDNA sequence:

AB043635.2 AB044556.1 AB178535.1 AB178536.1 AK128802.1 BC060797.1

6 DOTS entries:

DT.101981386 DT.95306194 DT.314905 DT.430579 DT.121103987 DT.91884658

24/65 AceView cDNA sequences (see all 65):

F09758 BE674937 AW298290 AI089398 AA262306 AI572539 CD673647 CD673646

AB044556 AI468587 BF197266 BF223304 AA894643 AI991628 AI174619 AW028673

BF511225 AA456039 AW052209 AI867881 W05503 F12120 AB043635 AI868540

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

PARD6G expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TCGTTCAGTG

About this image

PARD6G expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

10/11 LifeMap In Vivo Development Anatomical Compartments/Cells (see all 11)

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Lung

Trachea

Basal Cells

Lung

Bone

Rostral Endochondral Facial Bones

Bone

Rostral Skull Membranous Bones

Bone

Bone

Cartilage

Cartilage

Cartilage

Rostral Chondrocranium

Cartilage

Rostral Synchondroses

Cartilage

Synchondroses

Cartilage

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

Stem Cell Differentiation: 2 LifeMap Cells

Name

Category

PureStem™ myogenic progenitor Z11 (Embryonic Progenitor Cell)

Heart, Myocardium, Smooth Muscle

PureStem™ progenitor Z1 (Embryonic Progenitor Cell)

See PARD6G Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for PARD6G

SOURCE GeneReport for Unigene cluster: Hs.654920

UniProtKB/Swiss-Prot: PAR6G_HUMAN, Q9BYG4

Tissue specificity: Widely expressed, with a higher expression in fetal and adult kidney

SABiosciences Custom PCR Arrays for PARD6G

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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PARD6G

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PARD6G

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for PARD6G gene from 6/20 species (see all 20) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	PARD6G¹	par-6 partitioning defective 6 homolog gamma (C. elegans)	68.66(n) 72.16(a)		428511 XM_426065.3 XP_426065.3
lizard (Anolis carolinensis)	Reptilia	PARD6G⁶	--	68(a)	1 ↔ 1	4(53266647-53267498)
African clawed frog (Xenopus laevis)	Amphibia	Xl.1701²	Xenopus laevis transcribed sequence with moderate similarity more	73.99(n)		BX854029.1
zebrafish (Danio rerio)	Actinopterygii	Dr.27686²	Danio rerio par-6 partitioning defective 6-like protein more	76.61(n)		BC059186.1
fruit fly (Drosophila melanogaster)	Insecta	par-6^{1 , 3}	border cell migration³ CG5884-PA¹	53(a)³ 57.23(n)¹ 55.91(a)¹		16C1³ 32752¹ NM_133010.4¹ NP_573238.1¹
worm (Caenorhabditis elegans)	Secernentea	par-6^{1 , 3}	PDZ domain (Also known as DHR or GLGF).³ Protein PAR-6¹	55(a)³ 51.55(n)¹ 53.61(a)¹		I(12677659-12679516)³ 173137¹ NM_001047222.3¹ NP_001040687.1¹

ENSEMBL Gene Tree for PARD6G (if available)
TreeFam Gene Tree for PARD6G (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for PARD6G gene

PARD6B² PARD6A²

3 SIMAP similar genes for PARD6G using alignment to 5 protein entries: PAR6G_HUMAN (see all proteins):

16-5-5 PARD6B PARD6A

PARD6G for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 18 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs146336676^1,2		--	77914737(+)	`TCCAGC/GATGCT`	3	--	int¹		0	--	--	--	--
rs138276635^1,2		--	77914779(+)	`TGAGTA/TACTGA`	3	--	int¹		0	--	--	--	--
rs7229329^1,2	C,F,A,H	--	77914804(+)	`TTTGAC/ATCTTG`	3	--	int¹		24		NS EA NA WA	2644
rs7237819^1,2	C,F,A,H	--	77914844(+)	`AACCGT/CGCCAA`	3	--	int¹		10		NA EA WA	608
rs146308885^1,2		--	77914986(+)	`CCCTC-/AGAGAGT`	3	--	int¹		0	--	--	--	--
rs7233906^1,2	C,F,A	--	77914993(+)	`AGAGTA/GTGTGC`	3	--	int¹		8		NA WA	250
rs78970666^1,2		--	77915034(+)	`ACTTGA/GTAAAT`	3	--	int¹		0	--	--	--	--
rs7233511^1,2	C,F,A	--	77915113(+)	`TCATGC/TATTTT`	3	--	spd¹ int¹		7		NA WA	248
rs148660503^1,2		--	77915319(+)	`AGCCTA/CATTTC`	3	--	ut3¹ int¹		0	--	--	--	--
rs1132560^1,2	C,F,H	--	77915383(-)	`AAGAAG/AGAAGG`	3	--	ut3¹ int¹ trp³		24		MN NS EA NA WA CSA	2524

HapMap Linkage Disequilibrium report for PARD6G (77915115 - 78005429 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for PARD6G: --

SABiosciences Cancer Mutation PCR Assays

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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PARD6G for disorders About MalaCards

PARD6G for disorders About GeneDecksing

OMIM gene information: 608976 OMIM disorders: --

Human Genome Epidemiology (HuGE) Navigator: PARD6G (1 document)

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(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for PARD6G gene integrated from 9 sources:
(articles sorted by number of sources associating them with PARD6G)

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Human homologues of the Caenorhabditis elegans cell polarity protein PAR6 as an adaptor that links the small GTPases Rac and Cdc42 to atypical protein kinase C. (PubMed id 11260256)^{1, 2, 3} Noda Y.... Sumimoto H. (2001)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42. (PubMed id 10934474)^{1, 2} Joberty G.... Macara I.G. (2000)
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)¹ Rose J.E....Uhl G.R. (2010)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)¹ Ota T.... Sugano S. (2004)
Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network. (PubMed id 14676191)¹ Brajenovic M.... Drewes G. (2004)
PAR3beta, a novel homologue of the cell polarity protein PAR3, localizes to tight junctions. (PubMed id 12459187)¹ Kohjima M.... Sumimoto H. (2002)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)
Atypical protein kinase C is involved in the evolutionarily conserved par protein complex and plays a critical role in establishing epithelia-specific junctional structures. (PubMed id 11257119)¹ Suzuki A.... Ohno S. (2001)

(in PubMed, OMIM, and NCBI Bookshelf)
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 84552	HGNC: 16076	AceView: PARD6G	Ensembl:ENSG00000178184	euGenes: HUgn84552
ECgene: PARD6G	Kegg: 84552	H-InvDB: PARD6G

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for PARD6G	Pharmacogenomics, SNPs, Pathways

Intellectual Property for PARD6G gene
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Patent Information for PARD6G gene:
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par-6 partitioning defective 6 homolog gamma (C. elegans)

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par-6 partitioning defective 6 homolog gamma (C. elegans)

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