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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

PAQR8 Gene

protein-coding   GIFtS: 45
GCID: GC06P052226

Progestin And AdipoQ Receptor Family Member VIII

(Previous name: chromosome 6 open reading frame 33)
(Previous symbol: C6orf33)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Progestin And AdipoQ Receptor Family Member VIII1 2 3     Progestin And AdipoQ Receptor Family Member 82 3
C6orf331 2 3 5     MPR Beta2 3
LMPB12 3 5     Chromosome 6 Open Reading Frame 331
MPRB2 3 5     Lysosomal Membrane Protein In Brain-12
Lysosomal Membrane Protein In Brain 12 3     Membrane Progestin Receptor Beta2

External Ids:    HGNC: 157081   Entrez Gene: 853152   Ensembl: ENSG000001709157   OMIM: 6077805   UniProtKB: Q8TEZ73   

Export aliases for PAQR8 gene to outside databases

Previous GC identifers: GC06P052335 GC06P052058


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for PAQR8 Gene: 
PAQR8 (progestin and adipoQ receptor family member VIII) is a protein-coding gene. Diseases associated with PAQR8 include epilepsy with generalized tonic-clonic seizures, and juvenile myoclonic epilepsy. GO annotations related to this gene include steroid binding. An important paralog of this gene is PAQR7.

UniProtKB/Swiss-Prot: MPRB_HUMAN, Q8TEZ7
Function: Steroid membrane receptor. Binds progesterone. May be involved in oocyte maturation (By similarity)

Gene Wiki entry for PAQR8 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NC_018917.2  NT_007592.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the PAQR8 gene promoter:
         GR   ISGF-3   GR-beta   NRSF form 1   NRSF form 2   S8   Nkx6-1   IRF-7A   GR-alpha   En-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidPAQR8 promoter sequence
   Search SABiosciences Chromatin IP Primers for PAQR8

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PAQR8


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p12.1   Ensembl cytogenetic band:  6p12.2   HGNC cytogenetic band: 6p12

PAQR8 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PAQR8 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P052226:  view genomic region     (about GC identifiers)

Start:
52,226,219 bp from pter      End:
52,272,575 bp from pter
Size:
46,357 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: MPRB_HUMAN, Q8TEZ7 (See protein sequence)
Recommended Name: Membrane progestin receptor beta  
Size: 354 amino acids; 40464 Da
Subcellular location: Cell membrane; Multi-pass membrane protein. Note=Colocalizes with a lysosomal protein
CTSD/cathepsin D
Sequence caution: Sequence=AAR08374.1; Type=Erroneous initiation; Sequence=CAC05478.1; Type=Erroneous initiation;
Secondary accessions: B2RCF6 Q86WL0 Q8N6D3 Q9HD02

Explore the universe of human proteins at neXtProt for PAQR8: NX_Q8TEZ7

Explore proteomics data for PAQR8 at MOPED 

PAQR8 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

PAQR8 Protein Expression

REFSEQ proteins: NP_588608.1  
ENSEMBL proteins: 
 ENSP00000427161   ENSP00000406197   ENSP00000353953  

Human Recombinant Protein Products for PAQR8: 
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Novus Biologicals PAQR8 Protein
Novus Biologicals PAQR8 Lysate
Browse Sino Biological Recombinant Proteins
Browse Sino Biological Cell Lysates 
Browse ProSpec Recombinant Proteins
Browse Proteins at Cloud-Clone Corp. 

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005886plasma membrane IEA--
GO:0016021integral to membrane IEA--

PAQR8 for ontologies           About GeneDecksing



PAQR8 Antibody Products: 
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LSBio Antibodies in human, mouse, rat for PAQR8 

Assay Products for PAQR8: 
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Browse CLIAs at Cloud-Clone Corp.


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section
1 InterPro protein domain:
 IPR004254 HlyIII-related

Graphical View of Domain Structure for InterPro Entry Q8TEZ7

ProtoNet protein and cluster: Q8TEZ7

1 Blocks protein domain: IPB004254 Hly-III related proteins

UniProtKB/Swiss-Prot: MPRB_HUMAN, Q8TEZ7
Similarity: Belongs to the ADIPOR family


PAQR8 for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Molecular Function:

     UniProtKB/Swiss-Prot Summary: MPRB_HUMAN, Q8TEZ7
Function: Steroid membrane receptor. Binds progesterone. May be involved in oocyte maturation (By similarity)

     Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005496steroid binding IEA--
     
PAQR8 for ontologies           About GeneDecksing


Phenotypes:
     2 GenomeRNAi human phenotypes for PAQR8:
 Decreased influenza A/WSN/33 r  Increased S DNA content 

Animal Models:
   inGenious Targeting Laboratory - Custom generated mouse model solutions for PAQR8 
   inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for PAQR8

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for PAQR8 
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for PAQR8 

miRNA
Products:
    
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat PAQR8
8/38 QIAGEN miScript miRNA Assays for microRNAs that regulate PAQR8 (see all 38):
hsa-miR-100* hsa-miR-4328 hsa-miR-765 hsa-miR-4305 hsa-miR-485-3p hsa-miR-138-2* hsa-miR-500a hsa-miR-877*
SwitchGear 3'UTR luciferase reporter plasmidPAQR8 3' UTR sequence
Inhib. RNA
Products:
    
Browse for Gene Knock-down Tools from EMD Millipore
OriGene RNAi products in human, mouse, rat for PAQR8
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat PAQR8

Gene Editing
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DNA2.0 Custom Protein Engineering Service for PAQR8
Sirion Biotech Customized adenovirus for overexpression of PAQR8

Clone
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Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
OriGene clones in human, mouse for PAQR8 (see all 7)
OriGene ORF clones in mouse, rat for PAQR8
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: PAQR8 (NM_133367)
Browse Sino Biological Human cDNA Clones
DNA2.0 Custom Codon Optimized Gene Synthesis Service for PAQR8
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PAQR8
Sirion Biotech Customized lentivirus for stable overexpression of PAQR8 
                     Customized lentivirus expression plasmids for stable overexpression of PAQR8 

Cell Line
Products:
     
GenScript Custom overexpressing Cell Line Services for PAQR8
Search LifeMap BioReagents cell lines for PAQR8
In Situ Assay
Products:
   

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PAQR8


(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section



Interactions:

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for PAQR8

Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0007275multicellular organismal development IEA--
GO:0030154cell differentiation IEA--
GO:0048477oogenesis IEA--

PAQR8 for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section
Browse Small Molecules at EMD Millipore
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for PAQR8 (MPRB)

Search CenterWatch for drugs/clinical trials and news about PAQR8 / MPRB

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for PAQR8 gene: 
NM_133367.4  

Unigene Cluster for PAQR8:

Progestin and adipoQ receptor family member VIII
Hs.239388  [show with all ESTs]
Unigene Representative Sequence: NM_133367
3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000512121 ENST00000442253(uc003pao.4) ENST00000360726
miRNA
Products:
     
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat PAQR8
8/38 QIAGEN miScript miRNA Assays for microRNAs that regulate PAQR8 (see all 38):
hsa-miR-100* hsa-miR-4328 hsa-miR-765 hsa-miR-4305 hsa-miR-485-3p hsa-miR-138-2* hsa-miR-500a hsa-miR-877*
SwitchGear 3'UTR luciferase reporter plasmidPAQR8 3' UTR sequence
Inhib. RNA
Products:
     
Browse for Gene Knock-down Tools from EMD Millipore
OriGene RNAi products in human, mouse, rat for PAQR8
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat PAQR8
Clone
Products:
     
OriGene clones in human, mouse for PAQR8 (see all 7)
OriGene ORF clones in mouse, rat for PAQR8
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: PAQR8 (NM_133367)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for PAQR8
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PAQR8
Sirion Biotech Customized lentivirus for stable overexpression of PAQR8 
                     Customized lentivirus expression plasmids for stable overexpression of PAQR8 
Primer
Products:
    
OriGene qPCR primer pairs and template standards for PAQR8
OriGene qSTAR qPCR primer pairs in human, mouse for PAQR8
SABiosciences RT2 qPCR Primer Assay in human, mouse, rat PAQR8
  QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PAQR8
  QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PAQR8

Additional mRNA sequence: 

AF313619.1 AF347029.1 AJ420470.1 AK057083.1 AK093603.1 AK128085.1 AK315088.1 AY424286.1 
BC030664.2 

5 DOTS entries:

DT.116140  DT.95097355  DT.100776455  DT.101980435  DT.97791371 

24/143 AceView cDNA sequences (see all 143):

BU736633 AA662311 AI950886 BM798375 CD558648 AA508695 BM681978 BM679731 
AA948307 BF594216 BF439998 BM704467 AK128085 AI418869 CD370786 BQ016404 
AW006774 BQ183737 N39362 CA395770 BM729038 T78976 AA548663 T33606 

GeneLoc Exon Structure

2 Alternative Splicing Database (ASD) splice patterns (SP) for PAQR8    About this scheme

ExUns: 1 ^ 2 ^ 3 ^ 4
SP1:                        
SP2:        -     -         


ECgene alternative splicing isoforms for PAQR8

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

PAQR8 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: --
PAQR8 Expression
About this image


See PAQR8 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for PAQR8

SOURCE GeneReport for Unigene cluster: Hs.239388

UniProtKB/Swiss-Prot: MPRB_HUMAN, Q8TEZ7
Tissue specificity: Expressed in brain and spinal cord. Also expressed in kidney and testis

    SABiosciences Custom PCR Arrays for PAQR8
Primer
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OriGene qPCR primer pairs and template standards for PAQR8
OriGene qSTAR qPCR primer pairs in human, mouse for PAQR8
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QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PAQR8
QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PAQR8
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PAQR8

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for PAQR8 gene from 5/12 species (see all 12)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Paqr81 , 5 progestin and adipoQ receptor family member VIII1, 5 86.63(n)1
94.07(a)1
  1 (6.50 cM)5
742291  NM_028829.31  NP_083105.31 
 208906225 
chicken
(Gallus gallus)
Aves PAQR81 progestin and adipoQ receptor family member VIII 76.58(n)
82.15(a)
  422042  NM_001008462.1  NP_001008462.1 
African clawed frog
(Xenopus laevis)
Amphibia mpr-A-prov2 putative membrane progesterone receptor 74.17(n)    AY149119.1 
zebrafish
(Danio rerio)
Actinopterygii mprb2 membrane progestin receptor beta 73.52(n)   368254  AY149120.1 
worm
(Caenorhabditis elegans)
Secernentea K11C4.26
Protein K11C4.2
25(a)
1 → many
V(6895088-6896786)


ENSEMBL Gene Tree for PAQR8 (if available)
TreeFam Gene Tree for PAQR8 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
Paralogs for PAQR8 gene
PAQR72  PAQR92  PAQR62  PAQR52  
1 SIMAP similar gene for PAQR8 using alignment to 3 protein entries:     MPRB_HUMAN (see all proteins):
PAQR7

PAQR8 for paralogs           About GeneDecksing



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

10/926 SNPs in PAQR8 are shown (see all 926)    About this table     
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 6 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs47152981,2
C,H--52225036(+) ACTTGC/GAAACA 1 -- us2k1 tfbs39Minor allele frequency- G:0.01NA WA CSA 135
rs1148285051,2
F--52225096(+) ATGCAC/TGTTCA 1 -- us2k11Minor allele frequency- T:0.01WA 118
rs1836579721,2
--52225274(+) GCTCCC/TGGCTG 1 -- us2k10--------
rs734439731,2
C--52225332(+) GCTAAC/ACTGTA 1 -- us2k12Minor allele frequency- A:0.07WA 120
rs1512074641,2
--52225382(+) ACTCCC/TTCTCA 1 -- us2k10--------
rs1409795251,2
--52225437(+) TTTGAC/TGATAA 1 -- us2k10--------
rs21472061,2
C,F,H--52225514(-) CTTTGC/TTCCCT 1 -- us2k119Minor allele frequency- T:0.37MN EA NS NA CSA WA 3584
rs789004201,2
C,F--52225533(+) GACCTC/TCTGTG 1 -- us2k11Minor allele frequency- T:0.17NA 120
rs1154471391,2
C--52225561(+) CACCTA/GTAAGT 1 -- us2k10--------
rs1149643141,2
C,F--52225799(+) ATTTTT/CGTATT 1 -- us2k11Minor allele frequency- C:0.15NA 120

HapMap Linkage Disequilibrium report for PAQR8 (52226219 - 52272575 bp)

Structural Variations
     Database of Genomic Variants (DGV) 2 variations for PAQR8:    About this table     
Variant IDTypeSubtypePubMed ID
nsv527443CNV Loss19592680
esv21698CNV Gain19812545

SABiosciences Cancer Mutation PCR Assays
SeqTarget long-range PCR primers for resequencing PAQR8
DNA2.0 Custom Variant and Variant Library Synthesis for PAQR8

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section
OMIM gene information: 607780    OMIM disorders: --

4 diseases for PAQR8:    About MalaCards
epilepsy with generalized tonic-clonic seizures    juvenile myoclonic epilepsy    retinitis    ovarian cancer

1 disease from the University of Copenhagen DISEASES database for PAQR8:
Epilepsy with generalized tonic-clonic seizures

PAQR8 for disorders           About GeneDecksing


Export disorders for PAQR8 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

PubMed articles for PAQR8 gene, integrated from 9 sources (see all 16):
(articles sorted by number of sources associating them with PAQR8)
    Utopia: connect your pdf to the dynamic
world of online information

  1. A novel gene in the chromosomal region for juvenile myoclonic epilepsy on 6p12 encodes a brain-specific lysosomal membrane protein. (PubMed id 11676489)1, 2, 3, 9 Suzuki T.... Yamakawa K. (2001)
  2. PAQR proteins: a novel membrane receptor family defined by an ancient 7-transmembrane pass motif. (PubMed id 16044242)1, 2 Tang Y.T....Funk W.D. (2005)
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
  5. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (2003)
  6. The further redefining of steroid-mediated signaling. (PubMed id 12606724)1, 2 Hammes S.R. (2003)
  7. Identification, classification, and partial characterization of genes in humans and other vertebrates homologous to a fish membrane progestin receptor. (PubMed id 12601167)1, 2 Zhu Y.... Thomas P. (2003)
  8. Cloning, expression, and characterization of a membrane progestin receptor and evidence it is an intermediary in meiotic maturation of fish oocytes. (PubMed id 12574519)1, 3 Zhu Y....Thomas P. (2003)
  9. Expression of membrane progesterone receptors (mPR/PA QR) in ovarian cancer cells: implications for progesterone-induced signaling ev ents. (PubMed id 21761364)1 Charles N.J....Lange C.A. (2010)
  10. Heterologous expression of human mPRalpha, mPRbeta and mPRgamma in yeast confirms their ability to function as membrane progesterone receptors. (PubMed id 18603275)1 Smith J.L....Lyons T.J. (2008)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section
 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section
Entrez Gene: 85315 HGNC: 15708 AceView: C6orf33 Ensembl:ENSG00000170915 euGenes: HUgn85315
ECgene: PAQR8 H-InvDB: PAQR8

(According to HUGE)
About This Section
  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
NameDescription
PharmGKB entry for PAQR8 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
About This Section
Patent Information for PAQR8 gene:
Search GeneIP for patents involving PAQR8

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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 EMD Millipore Custom Antibody & Bulk Services
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GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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Category
(GIFtS: 73)
transforming growth factor, beta 1
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The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

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