Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

PAQR5 Gene

protein-coding   GIFtS: 46
GCID: GC15P069591

progestin and adipoQ receptor family member V
 Explore 3 diseases affiliated with
PAQR5 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for PAQR5    

Aliases
for PAQR5 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Progestin And AdipoQ Receptor Family Member V1 2 3
MPRG1 2 3 5
Progestin And AdipoQ Receptor Family Member 52 3
MPR Gamma2 3
FLJ201901
Membrane Progestin Receptor Gamma2

External Ids:    HGNC: 296451   Entrez Gene: 548522   Ensembl: ENSG000001378197   OMIM: 6077815   UniProtKB: Q9NXK63   

Export aliases for PAQR5 gene to outside databases

Previous GC identifers: GC15P067379 GC15P046424


Summaries
for PAQR5 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
UniProtKB/Swiss-Prot: MPRG_HUMAN, Q9NXK6
Function: Steroid membrane receptor. Binds progesterone. May be involved in oocyte maturation




Genomic Views
for PAQR5 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000015.9  NC_018926.1  NT_010194.17  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the PAQR5 gene promoter:
         SRF   CREB   AML1a   SRF (504 AA)   deltaCREB   Ik-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: PAQR5 promoter sequence
   Search SABiosciences Chromatin IP Primers for PAQR5

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PAQR5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q23   Ensembl cytogenetic band:  15q23   HGNC cytogenetic band: 15q22.31

PAQR5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PAQR5 gene location

GeneLoc information about chromosome 15         GeneLoc Exon Structure

GeneLoc location for GC15P069591:  view genomic region     (about GC identifiers)

Start:
 69,591,286 bp from pter      End:
 69,700,119 bp from pter
Size:
 108,834 bases      Orientation:
 plus strand

Proteins
for PAQR5 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: MPRG_HUMAN, Q9NXK6 (See protein sequence)
Recommended Name: Membrane progestin receptor gamma  
Size: 330 amino acids; 38014 Da
Subcellular location: Membrane; Multi-pass membrane protein (By similarity)
Secondary accessions: Q8IXU2

Explore the universe of human proteins at neXtProt for PAQR5: NX_Q9NXK6

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9NXK6

    • PAQR5 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_001098024.1  NP_060175.3  

    ENSEMBL proteins: 
     ENSP00000378803   ENSP00000453009   ENSP00000453526   ENSP00000343877  

    Human Recombinant Protein Products: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate (see all 2): PAQR5
    OriGene Custom Protein Services for PAQR5 
    GenScript Custom Purified and Recombinant Proteins Services for PAQR5
    Novus Biologicals PAQR5 Protein
    Novus Biologicals PAQR5 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Uscn

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral to membrane IEA--


    PAQR5 for ontologies           About GeneDecksing



    PAQR5 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for PAQR5 
    GenScript Custom Superior Antibodies Services for PAQR5
    Novus Biologicals PAQR5 Antibodies
    Search for Antibodies for PAQR5 at Abcam  
    Browse Antibodies at Uscn
    Search ThermoFisher Antibodies for PAQR5

    Assay Products for PAQR5: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Immunoassay Development
    Browse OriGene Fluorogenic Cell Assay Kits
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for PAQR5
    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs and CLIAs at Uscn

    Protein Domains /
    Families
    for PAQR5 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    PAQR5 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR004254 HlyIII-related

    Graphical View of Domain Structure for InterPro Entry Q9NXK6

    ProtoNet protein and cluster: Q9NXK6

    1 Blocks protein family: IPB004254 Hly-III related proteins

    UniProtKB/Swiss-Prot: MPRG_HUMAN, Q9NXK6
    Similarity: Belongs to the ADIPOR family


    Function
    for PAQR5 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: MPRG_HUMAN, Q9NXK6
    Function: Steroid membrane receptor. Binds progesterone. May be involved in oocyte maturation

    miRNA
    Products:            		 OriGene 3'-UTR Clone (see all 2): PAQR5
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat PAQR5
    8/38 QIAGEN miScript miRNA Assays for microRNAs that regulate PAQR5 (see all 38):
    hsa-miR-429 hsa-miR-200a hsa-miR-578 hsa-miR-519a hsa-miR-3916 hsa-miR-570 hsa-miR-374a* hsa-miR-141
    SwitchGear 3'UTR luciferase reporter plasmid: PAQR5 3' UTR sequence
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for PAQR5 (see all 7)
    OriGene shRNA RFP: PAQR5
    OriGene siRNA: PAQR5
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat PAQR5

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for PAQR5

    Clone
    Products:             		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PAQR5 (see all 4)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PAQR5 (see all 2)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector (see all 2): PAQR5 (NM_001104554)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for PAQR5
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PAQR5 

    Cell Line
    Products:             		GenScript Custom overexpressing Cell Line Services for PAQR5
    Search LifeMap BioReagents cell lines for PAQR5

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PAQR5

    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004872receptor activity ----
    GO:0005496steroid binding IEA--


    PAQR5 for ontologies           About GeneDecksing


    2 GenomeRNAi human phenotypes for PAQR5:
     Decreased cilium length  Decreased cilium length after  


    Pathways & Interactions
    for PAQR5 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for PAQR5

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007275multicellular organismal development IEA--
    GO:0030154cell differentiation IEA--
    GO:0048477oogenesis IEA--


    PAQR5 for ontologies           About GeneDecksing



    Drugs & Compounds
    for PAQR5 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for PAQR5
    Search CenterWatch for drugs/clinical trials and news about PAQR5 / MPRG 

    Transcripts
    for PAQR5 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for PAQR5 gene (2 alternative transcripts): 
    NM_001104554.1  NM_017705.3  

    Unigene Cluster for PAQR5:

    Progestin and adipoQ receptor family member V
    Hs.591096  [show with all ESTs]
    Unigene Representative Sequence: NM_001104554
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000395407(uc002arz.2) ENST00000558684 ENST00000561153 ENST00000561027
    ENST00000561250 ENST00000340965(uc002asa.2)

    miRNA
    Products:             		 OriGene 3'-UTR Clone (see all 2): PAQR5
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat PAQR5
    8/38 QIAGEN miScript miRNA Assays for microRNAs that regulate PAQR5 (see all 38):
    hsa-miR-429 hsa-miR-200a hsa-miR-578 hsa-miR-519a hsa-miR-3916 hsa-miR-570 hsa-miR-374a* hsa-miR-141
    SwitchGear 3'UTR luciferase reporter plasmid: PAQR5 3' UTR sequence
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for PAQR5 (see all 7)
    OriGene shRNA RFP: PAQR5
    OriGene siRNA: PAQR5
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat PAQR5
    Clone
    Products:             		 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PAQR5 (see all 4)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PAQR5 (see all 2)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector (see all 2): PAQR5 (NM_001104554)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for PAQR5
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PAQR5 
    Primer
    Products:            		 OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PAQR5
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat PAQR5
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PAQR5
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PAQR5

    Additional cDNA sequence: 

    AK000197.1 AY424283.1 BC039234.1 

    5 DOTS entries:

    DT.75134209  DT.100775777  DT.100677407  DT.65285895  DT.100732567 

    24/30 AceView cDNA sequences (see all 30):

    AW451937 AI203689 CR609133 AW263042 BG536358 BF434456 BC039234 BX497406 
    BX341442 AY424283 BG675011 BM906130 AK000197 BI824700 NM_017705 CA309136 
    BX114736 BX341441 AW779994 BQ021056 N78142 BG432621 BE747523 BQ010454 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for PAQR5    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8
    SP1:              -                                       
    SP2:                                                      


    ECgene alternative splicing isoforms for PAQR5

    Expression
    for PAQR5 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    PAQR5 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: AGCCACACTG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    PAQR5 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    1 LifeMap In Vivo Development Anatomical Compartment/Cell 
    Tissue Anatomical Compartment CellCategory (developmental path)
    BrainBlood Brain BarrierAdult Endothelial CellsBlood Brain Barrier, Endothelium
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See PAQR5 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for PAQR5

    SOURCE GeneReport for Unigene cluster: Hs.591096

    UniProtKB/Swiss-Prot: MPRG_HUMAN, Q9NXK6
    Tissue specificity: Expressed in the brain, lung, kidney, colon, adrenal and lung

        SABiosciences Custom PCR Arrays for PAQR5
    Primer
    Products:    		 OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PAQR5
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat PAQR5
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PAQR5
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PAQR5
    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PAQR5

    Orthologs
    for PAQR5 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of chordates.

    Orthologs for PAQR5 gene from 3/14 species (see all 14)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves PAQR56
    		 Uncharacterized protein
    		 52(a)
    		 1 ↔ 1
    		 10(21508053-21511017)
    lizard
    (Anolis carolinensis)    		 Reptilia PAQR56
    		 --
    		 53(a)
    		 1 ↔ 1
    		 GL343467.1(3555-9419)
    zebrafish
    (Danio rerio)    		 Actinopterygii zgc560162 hypothetical protein MGC56016 74.6(n)   393156  BC045864.1 


    ENSEMBL Gene Tree for PAQR5 (if available)
    TreeFam Gene Tree for PAQR5 (if available) 

    Paralogs
    for PAQR5 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for PAQR5 gene
    PAQR72  PAQR42  PAQR92  ADIPOR12  PAQR32  PAQR62  ADIPOR22  PAQR82  
    2 SIMAP similar genes for PAQR5 using alignment to 3 protein entries:     MPRG_HUMAN (see all proteins):
    PAQR6    PAQR7

    PAQR5 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for PAQR5
    PGOHUM00000261994


    Genomic Variants
    for PAQR5 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/2204 NCBI SNPs in PAQR5 are shown (see all 2204)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 15 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs752920361,2
    		--46522067(+) CCCAAG/ATCAGC 1 -- ds50011Minor allele frequency- A:0.01NA 120
    rs780258441,2
    		F,--46522659(+) AAATGC/TTTGTC 1 -- nc-transcript-variant3Minor allele frequency- T:0.06CSA WA 124
    rs1134104581,2
    		--46522704(+) TGTGCG/ATATGC 1 -- nc-transcript-variant1Minor allele frequency- A:0.50CSA 2
    rs734260121,2
    		C,--46523610(+) AAAGTC/TCACGC 1 -- int12Minor allele frequency- T:0.05WA 120
    rs1128412691,2
    		--46523671(+) GGCTAC/TGTGAC 1 -- int11Minor allele frequency- T:0.50CSA 2
    rs1115541691,2
    		--46523862(+) CCAGAG/TGGCAG 1 -- int11Minor allele frequency- T:0.50CSA 2
    rs745081581,2
    		F,--46523904(+) ACCCAG/ACAGCT 1 -- int11Minor allele frequency- A:0.02WA 118
    rs734260181,2
    		C,--46525689(+) GAATCC/ACATGA 1 -- int12Minor allele frequency- A:0.05WA 120
    rs734260201,2
    		C,--46525699(+) ATTAAG/ATGAAC 1 -- int12Minor allele frequency- A:0.05WA 120
    rs1125877281,2
    		C,--46526928(+) CTGTCC/TCATCC 1 -- int11Minor allele frequency- T:0.50NA 2

    HapMap Linkage Disequilibrium report for PAQR5 (69591286 - 69700119 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 2 variations for PAQR5
         2 CNVs: 43266 3966

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PAQR5
    DNA2.0 Custom Variant and Variant Library Synthesis for PAQR5

    Disorders / Diseases
    for PAQR5 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    PAQR5 for disorders           About GeneDecksing

    OMIM gene information: 607781    OMIM disorders: --

    3 diseases for PAQR5:    About MalaCards
    bipolar disorder    ovarian cancer    schizophrenia


    Export disorders for PAQR5 gene to outside databases

    Publications
    for PAQR5 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for PAQR5 gene, integrated from 9 sources (see all 12):
    (articles sorted by number of sources associating them with PAQR5)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. PAQR proteins: a novel membrane receptor family defined by an ancient 7-transmembrane pass motif. (PubMed id 16044242)1, 2 Tang Y.T....Funk W.D. (2005)
    2. Identification, classification, and partial characterization of genes in humans and other vertebrates homologous to a fish membrane progestin receptor. (PubMed id 12601167)1, 2 Zhu Y.... Thomas P. (2003)
    3. Cloning, expression, and characterization of a membrane progestin receptor and evidence it is an intermediary in meiotic maturation of fish oocytes. (PubMed id 12574519)1, 3 Zhu Y....Thomas P. (2003)
    4. Expression of membrane progesterone receptors (mPR/PA QR) in ovarian cancer cells: implications for progesterone-induced signaling ev ents. (PubMed id 21761364)1 Charles N.J....Lange C.A. (2010)
    5. A genome-wide meta-analysis identifies novel loci ass ociated with schizophrenia and bipolar disorder. (PubMed id 20889312)1 Wang K.S....Aragam N. (2010)
    6. Heterologous expression of human mPRalpha, mPRbeta and mPRgamma in yeast confirms their ability to function as membrane progesterone receptors. (PubMed id 18603275)1 Smith J.L....Lyons T.J. (2008)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    8. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
    9. The further redefining of steroid-mediated signaling. (PubMed id 12606724)2 Hammes S.R. (2003)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

    External Searches for PAQR5 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing PAQR5 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 54852 HGNC: 29645 AceView: MPRG Ensembl:ENSG00000137819 euGenes: HUgn54852
    ECgene: PAQR5 H-InvDB: PAQR5

    Other Databases showing PAQR5 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing PAQR5 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for PAQR5 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for PAQR5 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for PAQR5 gene:
    Search GeneIP for patents involving PAQR5

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    Products
    for PAQR5 gene

    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
    In Situ Hybridization Assays from
    Advanced Cell Diagnostics
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Phosphatase Activity Assays/Reagents   Browse Recombinant/Natural Proteins  
     Browse OriGene Antibodies   OriGene shRNA RFP for PAQR5  
     OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for PAQR5   OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PAQR5  
     OriGene Protein Over-expression Lysate for PAQR5   Browse OriGene Fluorogenic Cell Assay Kits  
     OriGene siRNA for PAQR5   OriGene 3'-UTR Clone for PAQR5  
     OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PAQR5   OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PAQR5  
     Browse OriGene GFP tagged cDNA clones in CMV expression vector   Browse OriGene MicroRNA Expression Plasmids  
     Browse OriGene basic RS shRNAs   Browse OriGene validated miRNA SYBR primer pairs  
     Browse OriGene full length recombinant human proteins expressed in human HEK293 cells   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for PAQR5   OriGene Custom Protein Services for PAQR5  
     OriGene Custom Immunoassay Development  

         		 
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat PAQR5
     QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PAQR5
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PAQR5
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat PAQR5
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PAQR5
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PAQR5
     GenScript Custom Purified and Recombinant Proteins Services for PAQR5 GenScript cDNA clones with any tag delivered in your preferred vector for PAQR5
     GenScript Custom Assay Services for PAQR5 GenScript Custom Superior Antibodies Services for PAQR5
     GenScript Custom overexpressing Cell Line Services for PAQR5 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in PAQR5 promoter
     Search Chromatin IP Primers for PAQR5
     RT2 qPCR Primer Assay in human, mouse, rat PAQR5
     Search GNC Networks for PAQR5
     SABiosciences Custom PCR Arrays for PAQR5
     Search Tocris compounds for PAQR5
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological cDNA Clones
     Antibodies/Proteins Production Services
     Rabbit Monoclonal Antibody Platform
     Bulk Purchasing
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     PAQR5 antibodies
     PAQR5 proteins
     PAQR5 lysates
     Search for Antibodies for PAQR5 at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for PAQR5
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Browse ELISAs, CLIAs, Proteins, and Antibodies at Uscn
     Search LifeMap BioReagents cell lines for PAQR5
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PAQR5
     SwitchGear 3'UTR luciferase reporter plasmids for PAQR5
     SwitchGear Promoter luciferase reporter plasmids for PAQR5
     Search ThermoFisher Antibodies for PAQR5
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PAQR5
           
    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

    View Random Gene

    Category
    VWF
    (GIFTS: 73)
    von Willebrand factor
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 

    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Copyright © 1996-2013 , Weizmann Institute of Science. All Rights Reserved.
    Hot genes      Disease genes      PAQR5 gene at Home site.
    hostname: 356977-web1.xennexinc.com index build: 100 solr: 1.4