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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

PAQR3 Gene

protein-coding   GIFtS: 46
GCID: GC04M079808

Progestin And AdipoQ Receptor Family Member III

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Progestin And AdipoQ Receptor Family Member III1 2 3
RKTG2 3
Raf Kinase Trapping To Golgi2 3
Progestin And AdipoQ Receptor Family Member 32

External Ids:    HGNC: 301301   Entrez Gene: 1525592   Ensembl: ENSG000001632917   OMIM: 6145775   UniProtKB: Q6TCH73   

Export aliases for PAQR3 gene to outside databases

Previous GC identifers: GC04M080266 GC04M080297 GC04M080165 GC04M080027 GC04M075584


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for PAQR3 Gene: 
PAQR3 (progestin and adipoQ receptor family member III) is a protein-coding gene. Diseases associated with PAQR3 include melanoma, and colorectal cancer. An important paralog of this gene is PAQR4.

UniProtKB/Swiss-Prot: PAQR3_HUMAN, Q6TCH7
Function: Functions as a spatial regulator of RAF1 kinase by sequestrating it to the Golgi




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000004.11  NT_016354.19  NC_018915.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the PAQR3 gene promoter:
         COUP-TF1   ER-alpha   RP58   Tal-1   COUP   HNF-4alpha2   HNF-3beta   E47   HNF-4alpha1   COUP-TF   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for PAQR3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PAQR3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q21.21   Ensembl cytogenetic band:  4q21.21   HGNC cytogenetic band: 4q21

PAQR3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PAQR3 gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04M079808:  view genomic region     (about GC identifiers)

Start:
79,808,281 bp from pter      End:
79,860,592 bp from pter
Size:
52,312 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: PAQR3_HUMAN, Q6TCH7 (See protein sequence)
Recommended Name: Progestin and adipoQ receptor family member 3  
Size: 311 amino acids; 36217 Da
Subcellular location: Golgi apparatus membrane; Multi-pass membrane protein
Sequence caution: Sequence=BAG51571.1; Type=Erroneous initiation;
Secondary accessions: A8K5B7 B3KP59 Q6PIQ1 Q86X05 Q8NCP9
Alternative splicing: 4 isoforms:  Q6TCH7-1   Q6TCH7-2   Q6TCH7-3   Q6TCH7-4   (May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay)

Explore the universe of human proteins at neXtProt for PAQR3: NX_Q6TCH7

Explore proteomics data for PAQR3 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q6TCH7

  • PAQR3 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    PAQR3 Protein Expression
    REFSEQ proteins: NP_001035292.1  
    ENSEMBL proteins: 
     ENSP00000426875   ENSP00000344203   ENSP00000425080   ENSP00000421981   ENSP00000378959  
     ENSP00000422357   ENSP00000420848   ENSP00000370019   ENSP00000295462  

    Human Recombinant Protein Products for PAQR3: 
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    Browse OriGene Protein Over-expression Lysates
    OriGene Custom MassSpec 
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    Novus Biologicals PAQR3 Protein
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for PAQR3 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane IEA--
    GO:0016021integral to membrane IEA--

    PAQR3 for ontologies           About GeneDecksing



    PAQR3 Antibody Products: 
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    LSBio Antibodies in human, mouse, rat for PAQR3 

    Assay Products for PAQR3: 
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    Cloud-Clone Corp. ELISAs for PAQR3 
    Cloud-Clone Corp. CLIAs for PAQR3


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR004254 HlyIII-related

    Graphical View of Domain Structure for InterPro Entry Q6TCH7

    ProtoNet protein and cluster: Q6TCH7

    1 Blocks protein domain: IPB004254 Hly-III related proteins

    UniProtKB/Swiss-Prot: PAQR3_HUMAN, Q6TCH7
    Similarity: Belongs to the ADIPOR family


    PAQR3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: PAQR3_HUMAN, Q6TCH7
    Function: Functions as a spatial regulator of RAF1 kinase by sequestrating it to the Golgi

    Phenotypes:
         2 GenomeRNAi human phenotypes for PAQR3:

     Decreased cilium length  Decreased cilium length after  

         4 MGI mutant phenotypes (inferred from 1 allele(MGI details for Paqr3):
     cellular  homeostasis/metabolism  integument  tumorigenesis 

    PAQR3 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Paqr3tm1Ychn for PAQR3

       inGenious Targeting Laboratory - Custom generated mouse model solutions for PAQR3 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for PAQR3

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for PAQR3 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for PAQR3 

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat PAQR3
    8/43 QIAGEN miScript miRNA Assays for microRNAs that regulate PAQR3 (see all 43):
    hsa-miR-142-5p hsa-miR-607 hsa-miR-562 hsa-miR-199a-3p hsa-miR-15a hsa-miR-29a hsa-miR-374a hsa-miR-10b*
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    Gene Editing
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    Sirion Biotech Customized adenovirus for overexpression of PAQR3

    Clone
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    OriGene clones in human, mouse for PAQR3 (see all 8)
    OriGene ORF clones in mouse, rat for PAQR3
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: PAQR3 (NM_001040202)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for PAQR3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PAQR3
    Sirion Biotech Customized lentivirus for stable overexpression of PAQR3 
                         Customized lentivirus expression plasmids for stable overexpression of PAQR3 

    Cell Line
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    Search LifeMap BioReagents cell lines for PAQR3
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PAQR3


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for PAQR3

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    2 Interacting proteins for PAQR3 (ENSP000003700194) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RAF1ENSP000002518494STRING: ENSP00000251849
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for PAQR3

    Search CenterWatch for drugs/clinical trials and news about PAQR3

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for PAQR3 gene (2 alternative transcripts): 
    NM_177453.2  NM_001040202.1  

    Unigene Cluster for PAQR3:

    Progestin and adipoQ receptor family member III
    Hs.657312  [show with all ESTs]
    Unigene Representative Sequence: NM_001040202
    14 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000512760 ENST00000342820(uc003hlm.3 uc003hln.3) ENST00000511594
    ENST00000512733(uc003hlp.1 uc003hlq.1) ENST00000515541 ENST00000503343
    ENST00000395594 ENST00000515853 ENST00000505715 ENST00000512299 ENST00000505735
    ENST00000508599 ENST00000380645 ENST00000295462
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat PAQR3
    8/43 QIAGEN miScript miRNA Assays for microRNAs that regulate PAQR3 (see all 43):
    hsa-miR-142-5p hsa-miR-607 hsa-miR-562 hsa-miR-199a-3p hsa-miR-15a hsa-miR-29a hsa-miR-374a hsa-miR-10b*
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for PAQR3
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat PAQR3
    Clone
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    OriGene clones in human, mouse for PAQR3 (see all 8)
    OriGene ORF clones in mouse, rat for PAQR3
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: PAQR3 (NM_001040202)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for PAQR3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PAQR3
    Sirion Biotech Customized lentivirus for stable overexpression of PAQR3 
                         Customized lentivirus expression plasmids for stable overexpression of PAQR3 
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for PAQR3
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat PAQR3
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PAQR3
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PAQR3

    Additional mRNA sequence: 

    AK055774.1 AK126273.1 AK291232.1 AL080110.1 AY424281.1 BX648346.1 

    11 DOTS entries:

    DT.101982068  DT.101955948  DT.121256326  DT.86836949  DT.212016  DT.40127776  DT.121256234  DT.95280119 
    DT.99997657  DT.40121851  DT.75183646 

    24/99 AceView cDNA sequences (see all 99):

    CD108809 AA431680 BM984085 AI522291 AI024933 AL080110 AW954260 AK055774 
    BX105202 AY424281 AI123291 CR604581 CR606971 AW178412 AX775925 AL522824 
    BX648346 CB960485 BC047510 AI968693 BM546935 AV728911 BI091349 AA608718 

    GeneLoc Exon Structure

    5/9 Alternative Splicing Database (ASD) splice patterns (SP) for PAQR3 (see all 9)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10 ^ 11a · 11b · 11c ^ 12a · 12b ^ 13a · 13b ^ 14 ^ 15 ^ 16
    SP1:                                      -     -                                   -                       -     -     -                 -                     
    SP2:                                -     -     -                                   -     -     -           -     -     -                 -           -         
    SP3:                                      -     -                                   -     -                                                                     
    SP4:                                      -     -                                   -     -     -                                                               
    SP5:                                -     -     -                                   -     -     -                                                               


    ECgene alternative splicing isoforms for PAQR3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    PAQR3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ACAAAATATG
    PAQR3 Expression
    About this image


    See PAQR3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for PAQR3

    SOURCE GeneReport for Unigene cluster: Hs.657312

    UniProtKB/Swiss-Prot: PAQR3_HUMAN, Q6TCH7
    Tissue specificity: Widely expressed in a range of tissues

        SABiosciences Custom PCR Arrays for PAQR3
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PAQR3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for PAQR3 gene from 8/17 species (see all 17)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Paqr31 , 5 progestin and adipoQ receptor family member III1, 5 90.89(n)1
    97.75(a)1
      5 (47.29 cM)5
    2314741  NM_198422.21  NP_940814.11 
     970823295 
    chicken
    (Gallus gallus)
    Aves PAQR31 progestin and adipoQ receptor family member III 80.56(n)
    87.62(a)
      770386  XM_001233720.2  XP_001233721.1 
    lizard
    (Anolis carolinensis)
    Reptilia PAQR36
    Uncharacterized protein
    92(a)
    1 ↔ 1
    5(145396887-145409179)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.154542 Transcribed sequence with weak similarity to protein more 77.84(n)    BX714333.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc730982 hypothetical protein MGC73098 75.04(n)   393683  BC059466.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG75306
    --
    31(a)
    1 ↔ 1
    3R(10550482-10557231)
    worm
    (Caenorhabditis elegans)
    Secernentea paqr-36
    Protein PAQR-3
    29(a)
    1 ↔ 1
    IV(14379952-14383681)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes IZH16
    IZH26
    Membrane protein involved in zinc ion homeostasis,...
    Plasma membrane protein involved in zinc homeostas...
    22(a)
    20(a)
    many ↔ many
    many ↔ many
    IV(1434924-1435874)
    XV(323411-324364)


    ENSEMBL Gene Tree for PAQR3 (if available)
    TreeFam Gene Tree for PAQR3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for PAQR3 gene
    PAQR42  ADIPOR12  ADIPOR22  
    2 SIMAP similar genes for PAQR3 using alignment to 3 protein entries:     PAQR3_HUMAN (see all proteins):
    ADIPOR2    ADIPOR1

    PAQR3 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/446 SNPs in PAQR3 are shown (see all 446)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 4 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs12991291,2
    C,F,O,H--79838676(+) AGGACC/TGTATT 1 -- ds500128Minor allele frequency- T:0.10NS EA NA WA CSA 2497
    rs623080021,2
    C--79838691(+) CCTCTT/GTAGTG 1 -- ds50014Minor allele frequency- G:0.15NA WA EA 360
    rs773663041,2
    C--79838711(+) GTGAT-/TGAT  
            
    AATGC
    1 -- ds50010--------
    rs12750471,2
    C,F,O,A,H--79838762(+) AGCTGC/ATTCTT 1 -- ds500122Minor allele frequency- A:0.28NA NS EA WA CSA 1284
    rs93074461,2
    C,F,H--79838811(+) ATTTAG/CAGTGG 1 -- ds500124Minor allele frequency- C:0.15NS NA EA WA CSA 1042
    rs1502221581,2
    --79838820(+) GGACAC/GGGACC 1 -- ds50010--------
    rs1862022721,2
    --79838943(+) TTTTAC/TGGAAG 1 -- ds50010--------
    rs105182081,2
    C,F,H--79838944(+) TTTACG/AGAAGT 1 -- ds5001 ese317Minor allele frequency- A:0.13NS NA EA WA 1026
    rs1422606671,2
    C--79839277(+) TAAAA-/AAAA  
     TAAAAAC
    CAGCC
    1 -- ut310--------
    rs1113619571,2
    C--79839387(+) GTATAA/TTTTAA 1 -- ut310--------

    HapMap Linkage Disequilibrium report for PAQR3 (79808281 - 79860592 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for PAQR3:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2727859CNV Deletion23290073
    nsv879504CNV Loss21882294
    nsv829979CNV Gain17160897

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing PAQR3
    DNA2.0 Custom Variant and Variant Library Synthesis for PAQR3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 614577    OMIM disorders: --

    2 diseases for PAQR3:    About MalaCards
    melanoma    colorectal cancer


    PAQR3 for disorders           About GeneDecksing


    Export disorders for PAQR3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for PAQR3 gene, integrated from 9 sources (see all 13):
    (articles sorted by number of sources associating them with PAQR3)
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    1. PAQR proteins: a novel membrane receptor family defined by an ancient 7-transmembrane pass motif. (PubMed id 16044242)1, 2, 3 Tang Y.T....Funk W.D. (2005)
    2. Characterization of the topology and functional domains of RKTG. (PubMed id 18547165)1, 2 Luo X.... Chen Y. (2008)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. PAQR3 plays a suppressive role in the tumorigenesis of colorectal cancers. (PubMed id 22828136)1 Wang X....Chen Y. (2012)
    6. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    7. Regulation of G-protein signaling by RKTG via sequest ration of the G betagamma subunit to the Golgi apparatus. (PubMed id 19884349)1 Jiang Y....Chen Y. (2010)
    8. Adiponectin identified as an agonist for PAQR3/RKTG u sing a yeast-based assay system. (PubMed id 19519172)1 Garitaonandia I....Lyons T.J. (2009)
    9. RKTG sequesters B-Raf to the Golgi apparatus and inhibits the proliferation and tumorigenicity of human malignant melanoma cells. (PubMed id 18515281)1 Fan F....Chen Y. (2008)
    10. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 152559 HGNC: 30130 AceView: PAQR3 Ensembl:ENSG00000163291 euGenes: HUgn152559
    ECgene: PAQR3 H-InvDB: PAQR3

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for PAQR3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for PAQR3 gene:
    Search GeneIP for patents involving PAQR3

    GeneCards and IP:
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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