Aliases for PAQR3 Gene
External Ids for PAQR3 Gene
Previous GeneCards Identifiers for PAQR3 Gene
This gene encodes a seven-transmembrane protein localized in the Golgi apparatus in mammalian cells. The encoded protein belongs to the progestin and adipoQ receptor (PAQR) family. This protein functions as a tumor suppressor by inhibiting the Raf/MEK/ERK signaling cascade. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2017]
GeneCards Summary for PAQR3 Gene
PAQR3 (Progestin And AdipoQ Receptor Family Member 3) is a Protein Coding gene. Among its related pathways are RET signaling and Cytokine Signaling in Immune system. Gene Ontology (GO) annotations related to this gene include receptor activity. An important paralog of this gene is ADIPOR1.
UniProtKB/Swiss-Prot for PAQR3 Gene
Functions as a spatial regulator of RAF1 kinase by sequestrating it to the Golgi.