External Ids for PANX2 Gene
Previous GeneCards Identifiers for PANX2 Gene
The protein encoded by this gene belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 1 are abundantly expressed in central nervous system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 1 may form cell type-specific gap junctions with distinct properties. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
GeneCards Summary for PANX2 Gene
PANX2 (Pannexin 2) is a Protein Coding gene. Among its related pathways are Transmission across Electrical Synapses and Transmission across Chemical Synapses. Gene Ontology (GO) annotations related to this gene include channel activity and wide pore channel activity. An important paralog of this gene is PANX3.
UniProtKB/Swiss-Prot for PANX2 Gene
Structural component of the gap junctions and the hemichannels.