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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

PAMR1 Gene

protein-coding GIFtS: 48
GCID: GC11M035453

peptidase domain containing associated with muscle regeneration...

Explore 3 diseases affiliated with
PAMR1 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Peptidase Domain Containing Associated With Muscle Regeneration 1¹ ²		Regeneration-Associated Muscle Protease Homolog² ³
RAMP¹ ² ³		Inactive Serine Protease PAMR1²
DKFZP586H2123¹ ²		Regeneration Associated Muscle Protease²
Peptidase Domain-Containing Protein Associated With Muscle Regeneration 1² ³

External Ids:	HGNC: 24554¹	Entrez Gene: 25891²	Ensembl: ENSG00000149090⁷	UniProtKB: Q6UXH9³

Export aliases for PAMR1 gene to outside databases

Previous GC identifers: GC11M035410 GC11M035152

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: PAMR1_HUMAN, Q6UXH9

Function: May play a role in regeneration of skeletal muscle (By similarity)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000011.9 NC_018922.1 NT_009237.18

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the PAMR1 gene promoter:
AML1a FOXF2 MIF-1 Nkx2-5 Nkx5-1 NF-AT NF-AT2 FOXO4 NF-AT3 NF-AT1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: PAMR1 promoter sequence

Search SABiosciences Chromatin IP Primers for PAMR1

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PAMR1

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11p13 Ensembl cytogenetic band: 11p13 HGNC cytogenetic band: 11p13

PAMR1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PAMR1 gene location

GeneLoc information about chromosome 11 GeneLoc Exon Structure

GeneLoc location for GC11M035453: view genomic region (about GC identifiers)

Start:	35,453,370 bp from pter	End:	35,551,848 bp from pter
Size:	98,479 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: PAMR1_HUMAN, Q6UXH9 (See protein sequence)

Recommended Name: Inactive serine protease PAMR1 precursor

Size: 720 amino acids; 80199 Da

Subcellular location: Secreted (Potential)

Caution: Although related to peptidase S1 family, lacks the conserved active Ser residue in position 665 which is

replaced by a Thr, suggesting that it has no protease activity

Sequence caution: Sequence=AAQ15224.1; Type=Frameshift; Positions=334;

Secondary accessions: Q5EBL7 Q5JPI4 Q6N062 Q71RE9 Q96JW2 Q9Y432

Alternative splicing: 2 isoforms: Q6UXH9-1 Q6UXH9-2

Explore the universe of human proteins at neXtProt for PAMR1: NX_Q6UXH9

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q6UXH9

PAMR1 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (2 alternative transcripts):

NP_001001991.1 NP_056245.2

ENSEMBL proteins:

ENSP00000278360 ENSP00000368158 ENSP00000433868 ENSP00000432591 ENSP00000433024

ENSP00000368156

Human Recombinant Protein Products:

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	Uscn Proteins for PAMR1

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005576	extracellular region	IEA	--

PAMR1 for ontologies About GeneDecksing

PAMR1 Antibody Products:

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	Uscn Antibodies for PAMR1
	Search ThermoFisher Antibodies for PAMR1

Assay Products for PAMR1:

	Browse Kits and Assays available from EMD Millipore
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	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for PAMR1
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for PAMR1

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

PAMR1 for domains About GeneDecksing

5/7 InterPro domains/families (see all 7):

IPR001314 Peptidase_S1A

IPR000742 EG-like_dom

IPR000436 Sushi_SCR_CCP

IPR001254 Peptidase_S1

IPR000859 CUB_dom

Graphical View of Domain Structure for InterPro Entry Q6UXH9

ProtoNet protein and cluster: Q6UXH9

5 Blocks protein families:

IPB000436 Sushi domain/SCR domain/CCP module

IPB001254 Serine protease

IPB001314 Chymotrypsin serine protease family (S1) signature

IPB001881 EGF-like calcium-binding

IPB006210 Type I EGF

UniProtKB/Swiss-Prot: PAMR1_HUMAN, Q6UXH9

Similarity: Belongs to the peptidase S1 family

Similarity: Contains 1 CUB domain

Similarity: Contains 1 EGF-like domain

Similarity: Contains 1 peptidase S1 domain

Similarity: Contains 2 Sushi (CCP/SCR) domains

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: PAMR1_HUMAN, Q6UXH9

Function: May play a role in regeneration of skeletal muscle (By similarity)

Induction: Strongly down-regulated in muscle cell lines derived from biopsies of 5 Duchenne muscular dystrophy (DMD)

patients compared to a normal muscle cell line

miRNA Products:		OriGene 3'-UTR Clone (see all 2): PAMR1 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat PAMR1
		1 QIAGEN miScript miRNA Assays for microRNA that regulate PAMR1:
		hsa-miR-4318
		SwitchGear 3'UTR luciferase reporter plasmid: PAMR1 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for PAMR1 (see all 4) OriGene shRNA RFP: PAMR1 OriGene siRNA: PAMR1
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Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for PAMR1

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
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		GenScript: all cDNA clones in your preferred vector (see all 2): PAMR1 (NM_015430)
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		DNA2.0 Custom Codon Optimized Gene Synthesis Service for PAMR1
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PAMR1

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for PAMR1
		Search LifeMap BioReagents cell lines for PAMR1

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PAMR1

Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003824	catalytic activity	IEA	--
GO:0004252	serine-type endopeptidase activity	--	--

PAMR1 for ontologies About GeneDecksing

2 GenomeRNAi human phenotypes for PAMR1:

Decreased cilium length after

Synthetic lethal with Ras

Animal Models:
Mouse knock-out Pamr1^tm1Lex for PAMR1
1 MGI phenotypic allele

for Pamr1 (no phenotypes)

PAMR1 for phenotypes About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for PAMR1

Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006508	proteolysis	--	--

PAMR1 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for PAMR1
Search CenterWatch for drugs/clinical trials and news about PAMR1

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for PAMR1 gene (2 alternative transcripts):

NM_001001991.1 NM_015430.2

Unigene Cluster for PAMR1:

Peptidase domain containing associated with muscle regeneration 1

Hs.55044 [show with all ESTs]

Unigene Representative Sequence: BX640676

8 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000278360(uc001mwf.3) ENST00000378880(uc001mwg.3 uc010rew.2)

ENST00000532848(uc010rex.2) ENST00000527605 ENST00000531219 ENST00000529303

ENST00000534803 ENST00000378878

miRNA Products:		OriGene 3'-UTR Clone (see all 2): PAMR1 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat PAMR1
		1 QIAGEN miScript miRNA Assays for microRNA that regulate PAMR1:
		hsa-miR-4318
		SwitchGear 3'UTR luciferase reporter plasmid: PAMR1 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for PAMR1 (see all 4) OriGene shRNA RFP: PAMR1 OriGene siRNA: PAMR1
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat PAMR1

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PAMR1 (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PAMR1 (see all 2) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 2): PAMR1 (NM_015430)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for PAMR1
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PAMR1

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PAMR1 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat PAMR1
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PAMR1
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PAMR1

Additional cDNA sequence:

AF370388.1 AK027841.1 AK297092.1 AK300185.1 AK316188.1 AL050214.1 AL832391.1 AY358346.1

BC038457.1 BC089434.1 BX640676.1

3 DOTS entries:

DT.99982487 DT.100751276 DT.75178838

24/75 AceView cDNA sequences (see all 75):

AI420902 AA812954 BU742789 AY358346 BX399905 AA433935 BX282717 NM_015430

NM_001001991 AL701986 BQ694586 BE048236 CD514783 AI057206 AA460698 AI579963

AA989716 BG403264 AW069518 BQ014545 AW957662 AW028008 AA375185 BX439313

GeneLoc Exon Structure

4 Alternative Splicing Database (ASD) splice patterns (SP) for PAMR1 About this scheme

ExUns:	1a	·	1b	·	1c	^	2	^	3	^	4	^	5	^	6	^	7	^	8	^	9	^	10	^	11a	·	11b	^	12a	·	12b	^	13
SP1:																	-								-
SP2:																	-		-						-
SP3:
SP4:

ECgene alternative splicing isoforms for PAMR1

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

PAMR1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GCCACAGTAC

About this image

PAMR1 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

10/26 LifeMap In Vivo Development Anatomical Compartments/Cells (see all 26)

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Bone

Sacral Vertebrae

Osteochondro Mesenchymal Cells

Bone, Cartilage

Cartilage

Cervical Intervertebral Disc

Intervertebral Disc Annulus Fibrosus Cells

Cartilage

Cervical Intervertebral Disc

Intervertebral Disc Nucleus Pulposus Cells

Cartilage

Limb

Stylopod Synovial Joint

Cartilage

Ovary

Ovary

Bone

Rostral Endochondral Facial Bones

Bone

Rostral Skull Membranous Bones

Bone

Brain

Medulla Oblongata

Brain

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

Stem Cell Differentiation: 7 LifeMap Cells

Name

Category

PureStem™ myogenic progenitor Z11 (Embryonic Progenitor Cell)

Heart, Myocardium, Smooth Muscle

PureStem™ mesenchymal progenitor 7SMOO32 (Embryonic Progenitor Cell)

Adipose, Bone, Cartilage

PureStem™ mesenchymal progenitor 7PEND24 (Embryonic Progenitor Cell)

Cartilage, Neural Crest

PureStem™ mesenchymal progenitor 4D20.8 (Embryonic Progenitor Cell)

Lateral Plate Mesoderm, Neural Crest

PureStem™ progenitor EN27 (Embryonic Progenitor Cell)

PureStem™ progenitor W8 (Embryonic Progenitor Cell)

PureStem™ progenitor Z1 (Embryonic Progenitor Cell)

See PAMR1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for PAMR1

SOURCE GeneReport for Unigene cluster: Hs.55044

SABiosciences Custom PCR Arrays for PAMR1

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PAMR1 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat PAMR1
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PAMR1
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PAMR1

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PAMR1

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for PAMR1 gene from 3/10 species (see all 10) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	PAMR1¹	peptidase domain containing associated with muscle more	75.66(n) 80.34(a)		423158 XM_421084.3 XP_421084.2
lizard (Anolis carolinensis)	Reptilia	PAMR1⁶	--	76(a)	1 ↔ 1	1(54550265-54652074)
zebrafish (Danio rerio)	Actinopterygii	CU207301.13⁶	--	49(a)	1 ↔ 1	25(38224190-38239458)

ENSEMBL Gene Tree for PAMR1 (if available)
TreeFam Gene Tree for PAMR1 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for PAMR1 gene

PROZ² C1S² C1R² C1RL² F9² MASP1² F10² F2²

HPR² HP² PROC² F7² MASP2²

5 SIMAP similar genes for PAMR1 using alignment to 5 protein entries: PAMR1_HUMAN (see all proteins):

MASP1 EGF F9 SNED1 DKFZp586F0824

PAMR1 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 11 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs199577438^1,2	C	--	35453799(-)	`AACTTG/TGNNNN`	1	--	ut3¹		0	--	--	--	--
rs77851638^1,2	C	--	35455317(+)	`TGGAT-/GGAT AGACG`	1	--	int¹		0	--	--	--	--
rs74408561^1,2	C,	--	35455318(+)	`TGGATA/GGACGG`	1	--	int¹		0	--	--	--	--
rs34951313^1,2	C	--	35458239(+)	`CACACAC/-TTTGC`	2	--	int¹		1		NA	2
rs144855778^1,2	C	--	35466939(+)	`AGTGA-/ATGAGA`	2	--	int¹		0	--	--	--	--
rs57349789^1,2	C	--	35467136(+)	`ATTTAGATA/- ATCAT`	2	--	int¹		1		NA	2
rs76154597^1,2	C,	--	35500102(+)	`AGGGA-/GCTGCGCT`	1	--	int¹		0	--	--	--	--
rs184967541^1,2		--	35500136(+)	`TTCAAC/TTCCCT`	1	--	int¹		0	--	--	--	--
rs80269637^1,2	C,F,	--	35500154(+)	`CTTGCC/TTCTAC`	1	--	int¹		2		WA EA	238
rs595334^1,2	C,F,A,H,	--	35500292(-)	`TCTTTC/AAGACT`	1	--	int¹		5		NS EA WA	534

HapMap Linkage Disequilibrium report for PAMR1 (35453370 - 35551848 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for PAMR1
3 CNVs: 3845 71308 71307

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PAMR1

DNA2.0 Custom Variant and Variant Library Synthesis for PAMR1

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

PAMR1 for disorders About GeneDecksing

3 diseases for PAMR1: About MalaCards

duchenne muscular dystrophy muscular dystrophy muscular atrophy

Human Genome Epidemiology (HuGE) Navigator: PAMR1 (1 document)

Export disorders for PAMR1 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for PAMR1 gene, integrated from 9 sources (see all 14):
(articles sorted by number of sources associating them with PAMR1)

Utopia: connect your pdf to the dynamic
world of online information

Cloning of cDNA encoding a regeneration-associated muscle protease whose expression is attenuated in cell lines derived from Duchenne muscular dystrophy patients. (PubMed id 15111323)^{1, 2, 3, 9} Nakayama Y.... Hara T. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)^{1, 2} Clark H.F.... Gray A.M. (2003)
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)¹ Rose J.E....Uhl G.R. (2010)
The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)² Bechtel S.... Schupp I. (2007)
Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. (PubMed id 16335952)² Liu T.... Smith R.D. (2005)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)² Gerhard D.S....Malek J. (2004)
Large-scale cDNA transfection screening for genes related to cancer development and progression. (PubMed id 15498874)² Wan D....Gu J. (2004)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)
[Regenerative medicine of skeletal muscle] (PubMed id 16447752)⁹ Hara T....Nara N. (2005)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 25891	HGNC: 24554	AceView: DKFZP586H2123	Ensembl:ENSG00000149090	euGenes: HUgn25891
ECgene: PAMR1	H-InvDB: PAMR1

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for PAMR1	Pharmacogenomics, SNPs, Pathways

Intellectual Property for PAMR1 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for PAMR1 gene:
Search GeneIP for patents involving PAMR1

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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peptidase domain containing associated with muscle regeneration...

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PAMR1 Gene

peptidase domain containing associated with muscle regeneration...

Aliasesfor PAMR1 gene

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Genomic Viewsfor PAMR1 gene

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External Searches for PAMR1 gene

Genome Databases showing PAMR1 gene

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Specialized Databases showing PAMR1 gene

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Aliases
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Summaries
for PAMR1 gene

Genomic Views
for PAMR1 gene

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for PAMR1 gene

Protein Domains /
Families
for PAMR1 gene

Function
for PAMR1 gene

Pathways & Interactions
for PAMR1 gene

Drugs & Compounds
for PAMR1 gene

Transcripts
for PAMR1 gene

Expression
for PAMR1 gene

Orthologs
for PAMR1 gene

Paralogs
for PAMR1 gene

Genomic Variants
for PAMR1 gene

Disorders / Diseases
for PAMR1 gene

Publications
for PAMR1 gene

Intellectual Property
for PAMR1 gene

Products
for PAMR1 gene