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PAMR1 Gene

protein-coding   GIFtS: 49
GCID: GC11M035453

Peptidase Domain Containing Associated With Muscle Regeneration...

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Peptidase Domain Containing Associated With Muscle Regeneration 11 2     Regeneration-Associated Muscle Protease1
Peptidase Domain-Containing Protein Associated With Muscle Regeneration 12 3     DKFZP586H21232
Regeneration-Associated Muscle Protease Homolog2 3     Inactive Serine Protease PAMR12
RAMP2 3     Regeneration Associated Muscle Protease2

External Ids:    HGNC: 245541   Entrez Gene: 258912   Ensembl: ENSG000001490907   UniProtKB: Q6UXH93   

Export aliases for PAMR1 gene to outside databases

Previous GC identifers: GC11M035410 GC11M035152


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for PAMR1 Gene:
PAMR1 (peptidase domain containing associated with muscle regeneration 1) is a protein-coding gene. Diseases associated with PAMR1 include duchenne muscular dystrophy, and muscular atrophy.

UniProtKB/Swiss-Prot: PAMR1_HUMAN, Q6UXH9
Function: May play a role in regeneration of skeletal muscle (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000011.10  NC_018922.2  NT_009237.19  
Regulatory elements:
   Regulatory transcription factor binding sites in the PAMR1 gene promoter:
         AML1a   FOXF2   MIF-1   Nkx2-5   Nkx5-1   NF-AT   NF-AT2   FOXO4   NF-AT3   NF-AT1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidPAMR1 promoter sequence
   Search Chromatin IP Primers for PAMR1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat PAMR1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11p13   Ensembl cytogenetic band:  11p13   HGNC cytogenetic band: 11p13

PAMR1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PAMR1 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11M035453:  view genomic region     (about GC identifiers)

Start:
35,453,370 bp from pter      End:
35,551,848 bp from pter
Size:
98,479 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: PAMR1_HUMAN, Q6UXH9 (See protein sequence)
Recommended Name: Inactive serine protease PAMR1 precursor  
Size: 720 amino acids; 80199 Da
Caution: Although related to peptidase S1 family, lacks the conserved active Ser residue in position 665 which is
replaced by a Thr, suggesting that it has no protease activity
Sequence caution: Sequence=AAQ15224.1; Type=Frameshift; Positions=334;
Secondary accessions: Q5EBL7 Q5JPI4 Q6N062 Q71RE9 Q96JW2 Q9Y432
Alternative splicing: 2 isoforms:  Q6UXH9-1   Q6UXH9-2   

Explore the universe of human proteins at neXtProt for PAMR1: NX_Q6UXH9

Explore proteomics data for PAMR1 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn614
  • Modification sites at PhosphoSitePlus

  • See PAMR1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (4 alternative transcripts): 
    NP_001001991.1  NP_001269604.1  NP_001269605.1  NP_056245.2  

    ENSEMBL proteins: 
     ENSP00000278360   ENSP00000368158   ENSP00000433868   ENSP00000432591   ENSP00000433024  
     ENSP00000368156  

    PAMR1 Human Recombinant Protein Products:

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    Novus Biologicals PAMR1 Lysates
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    Browse ProSpec Recombinant Proteins
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    Selected InterPro protein domains (see all 7):
     IPR001314 Peptidase_S1A
     IPR000742 EG-like_dom
     IPR000436 Sushi_SCR_CCP
     IPR001254 Peptidase_S1
     IPR000859 CUB_dom

    Graphical View of Domain Structure for InterPro Entry Q6UXH9

    ProtoNet protein and cluster: Q6UXH9

    5 Blocks protein domains:
    IPB000436 Sushi domain/SCR domain/CCP module
    IPB001254 Serine protease
    IPB001314 Chymotrypsin serine protease family (S1) signature
    IPB001881 EGF-like calcium-binding
    IPB006210 Type I EGF


    UniProtKB/Swiss-Prot: PAMR1_HUMAN, Q6UXH9
    Similarity: Belongs to the peptidase S1 family
    Similarity: Contains 1 CUB domain
    Similarity: Contains 1 EGF-like domain
    Similarity: Contains 1 peptidase S1 domain
    Similarity: Contains 2 Sushi (CCP/SCR) domains


    PAMR1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: PAMR1_HUMAN, Q6UXH9
    Function: May play a role in regeneration of skeletal muscle (By similarity)
    Induction: Strongly down-regulated in muscle cell lines derived from biopsies of 5 Duchenne muscular dystrophy
    (DMD) patients compared to a normal muscle cell line

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003824catalytic activity IEA--
    GO:0004252serine-type endopeptidase activity ----
    GO:0005509calcium ion binding ----
    GO:0005515protein binding ----
         
    PAMR1 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for PAMR1:
     Decreased cilium length after   Synthetic lethal with Ras 

         1 MGI phenotypic allele for Pamr1 (no phenotypes)

    PAMR1 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Pamr1tm1Lex for PAMR1

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for PAMR1
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for PAMR1
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for PAMR1

    miRNA
    Products:
        
    miRTarBase miRNAs that target PAMR1:
    hsa-mir-93-3p (MIRT038765)

    Block miRNA regulation of human, mouse, rat PAMR1 using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate PAMR1:
    hsa-miR-4318
    SwitchGear 3'UTR luciferase reporter plasmidPAMR1 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for PAMR1
    Predesigned siRNA for gene silencing in human, mouse, rat PAMR1

    Gene Editing
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    GenScript: all cDNA clones in your preferred vector (see all 2): PAMR1 (NM_015430)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for PAMR1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PAMR1

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for PAMR1 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PAMR1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    PAMR1_HUMAN, Q6UXH9: Secreted (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    extracellular3
    endoplasmic reticulum1
    lysosome1
    mitochondrion1
    nucleus1
    plasma membrane1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region IEA--

    PAMR1 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for PAMR1
    Interactions:

        Search GeneGlobe Interaction Network for PAMR1

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006508proteolysis ----

    PAMR1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for PAMR1



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for PAMR1 gene (4 alternative transcripts): 
    NM_001001991.2  NM_001282675.1  NM_001282676.1  NM_015430.3  

    Unigene Cluster for PAMR1:

    Peptidase domain containing associated with muscle regeneration 1
    Hs.55044  [show with all ESTs]
    Unigene Representative Sequence: BX640676
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000278360(uc001mwf.3) ENST00000378880(uc001mwg.3 uc010rew.2)
    ENST00000532848(uc010rex.2) ENST00000527605 ENST00000531219 ENST00000529303
    ENST00000534803 ENST00000378878
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat PAMR1 using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate PAMR1:
    hsa-miR-4318
    SwitchGear 3'UTR luciferase reporter plasmidPAMR1 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for PAMR1
    Predesigned siRNA for gene silencing in human, mouse, rat PAMR1
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    GenScript: all cDNA clones in your preferred vector (see all 2): PAMR1 (NM_015430)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for PAMR1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PAMR1
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for PAMR1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat PAMR1
      QuantiTect SYBR Green Assays in human, mouse, rat PAMR1
      QuantiFast Probe-based Assays in human, mouse, rat PAMR1

    Additional mRNA sequence: 

    AF370388.1 AK027841.1 AK297092.1 AK300185.1 AK316188.1 AL050214.1 AL832391.1 AY358346.1 
    BC038457.1 BC089434.1 BX640676.1 

    3 DOTS entries:

    DT.99982487  DT.100751276  DT.75178838 

    Selected AceView cDNA sequences (see all 75):

    BX399905 AA989716 BX282717 NM_001001991 AI057206 BU742789 BQ694586 AA812954 
    AI579963 BE048236 NM_015430 AA433935 AY358346 CD514783 AA460698 AI420902 
    AL701986 BP381335 BM728083 AA430705 AI990243 AK027841 BC038457 AL050214 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for PAMR1    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11a · 11b ^ 12a · 12b ^ 13
    SP1:                                                  -                       -                           
    SP2:                                                  -     -                 -                           
    SP3:                                                                                                      
    SP4:                                                                                                      


    ECgene alternative splicing isoforms for PAMR1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    PAMR1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCCACAGTAC
    PAMR1 Expression
    About this image


    PAMR1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 16) fully expand
     
     Limb (Muscoskeletal System)    fully expand to see all 5 entries
             Interzone Cells Stylopod Synovial Joint
             Zeugopod
     
     Neural Tube (Nervous System)    fully expand to see all 3 entries
             Metencephalon
             Floor plate-like cells
     
     Cartilage (Muscoskeletal System)    fully expand to see all 3 entries
             Interzone Cells Stylopod Synovial Joint
             Intervertebral Disc
     
     Placenta (Extraembryonic Tissues)    fully expand to see all 3 entries
             Primordial Germ Cells Allantois
             Placenta-derived mesenchymal stem cells (family)
     
     Bone (Muscoskeletal System)    fully expand to see all 2 entries
             Osteochondro Mesenchymal Cells Vertebrae
             Autopod Long Bone
    PAMR1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    PAMR1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.55044
        Custom PCR Arrays for PAMR1
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PAMR1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for PAMR1 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Pamr11 , 5 peptidase domain containing associated with muscle more1, 5 86.11(n)1
    90.28(a)1
      2 (54.13 cM)5
    2106221  NM_173749.41  NP_776110.31 
     1025500125 
    chicken
    (Gallus gallus)
    Aves PAMR11 peptidase domain containing associated with muscle more 74.99(n)
    79.1(a)
      423158  XM_421084.4  XP_421084.3 
    lizard
    (Anolis carolinensis)
    Reptilia PAMR16
    peptidase domain containing associated with muscle...
    76(a)
    1 ↔ 1
    1(54550265-54652074)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia pamr11 peptidase domain containing associated with muscle more 68.47(n)
    67.22(a)
      448349  NM_001004944.1  NP_001004944.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5602951 inactive serine protease PAMR1-like 53.58(n)
    46.42(a)
      560295  XM_001919528.3  XP_001919563.3 


    ENSEMBL Gene Tree for PAMR1 (if available)
    TreeFam Gene Tree for PAMR1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for PAMR1 gene
    5 SIMAP similar genes for PAMR1 using alignment to 5 protein entries:     PAMR1_HUMAN (see all proteins):
    MASP1    EGF    F9    SNED1    DKFZp586F0824

    PAMR1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for PAMR1 (see all 2072)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1172020901,2
    F--35151939(+) CTTAAG/AGTGTC 2 -- ds50011Minor allele frequency- A:0.05EA 120
    rs1447423151,2
    --35152029(+) TTATAC/GACAAC 2 -- ds50010--------
    rs1900589251,2
    --35152068(+) AAACTG/TAGTGT 2 -- ds50010--------
    rs1826664531,2
    --35152155(+) GTGTTA/GGATCT 2 -- ds50010--------
    rs1481066931,2
    --35152176(+) AAGCAA/GAGGCA 2 -- ds50010--------
    rs1142967381,2
    F--35152206(+) CTCTGG/TTGTTT 2 -- ds50011Minor allele frequency- T:0.03WA 118
    rs1419482871,2
    --35152227(+) CTTATC/TGGAGG 2 -- ds50010--------
    rs14004871,2
    H--35152255(+) CCCCTG/AGCCCA 2 -- ds50015Minor allele frequency- A:0.00MN NS EA 602
    rs1880243471,2
    --35152283(+) AGAGTC/TGGTAT 2 -- ds50010--------
    rs14004881,2
    H--35152332(+) GGAATG/AATAGC 2 -- ds50015Minor allele frequency- A:0.00MN NS EA 602

    HapMap Linkage Disequilibrium report for PAMR1 (35453370 - 35551848 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for PAMR1:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv508624CNV Loss20534489
    esv23286CNV Gain19812545
    nsv832120CNV Gain17160897
    essv13578CNV CNV17122850

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing PAMR1
    DNA2.0 Custom Variant and Variant Library Synthesis for PAMR1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    5 diseases for PAMR1:    
    About MalaCards
    duchenne muscular dystrophy    muscular atrophy    muscular dystrophy    pulmonary function
    cervicitis


    PAMR1 for disorders           About GeneDecksing

    Genetic Association Database (GAD): PAMR1
    Human Genome Epidemiology (HuGE) Navigator: PAMR1 (1 document)

    Export disorders for PAMR1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for PAMR1 gene, integrated from 10 sources (see all 17):
    (articles sorted by number of sources associating them with PAMR1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning of cDNA encoding a regeneration-associated muscle protease whose expression is attenuated in cell lines derived from Duchenne muscular dystrophy patients. (PubMed id 15111323)1, 2, 3, 9 Nakayama Y.... Hara T. (Am. J. Pathol. 2004)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (Genome Res. 2003)
    5. A genome-wide association study (GWAS) for bronchopulmonary dysplasia. (PubMed id 23897914)1 Wang H....O'Brodovich H.M. (Pediatrics 2013)
    6. Common variants in left/right asymmetry genes and pathways are associated with relative hand skill. (PubMed id 24068947)1 Brandler W.M....Paracchini S. (PLoS Genet. 2013)
    7. Framingham Heart Study genome-wide association: results for pulmonary function measures. (PubMed id 17903307)4 Wilk J.B....O'Connor G.T. (BMC Med. Genet. 2007)
    8. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (BMC Genomics 2007)
    9. Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. (PubMed id 16335952)2 Liu T.... Smith R.D. (J. Proteome Res. 2005)
    10. Large-scale cDNA transfection screening for genes related to cancer development and progression. (PubMed id 15498874)2 Wan D....Gu J. (Proc. Natl. Acad. Sci. U.S.A. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 25891 HGNC: 24554 AceView: DKFZP586H2123 Ensembl:ENSG00000149090 euGenes: HUgn25891
    ECgene: PAMR1 H-InvDB: PAMR1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for PAMR1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for PAMR1 gene:
    Search GeneIP for patents involving PAMR1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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