PALMD Gene
protein-coding GIFtS : 47
GCID: GC01 P100111
palmdelphin (Previous symbol: C1orf11 )
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Aliasesfor PALMD gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases Palmdelphin 1 C1orf111 2 3 PALML1 2 3 Paralemnin-Like Protein2 3 FLJ202711
Export aliases for PALMD gene to outside databases Previous GC identifers: GC01P100909 GC01P099237 GC01P099402 GC01P099574 GC01P099823 GC01P098233
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Summariesfor PALMD gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section --
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Genomic Viewsfor PALMD gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000001.10 NC_018912.1 NT_032977.9 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the PALMD gene promoter: GR FOXF2 GR-beta AP-4 PPAR-alpha POU2F1 POU2F1a FOXJ2 (long isoform) FOXJ2 GR-alpha Other transcription factors Search SABiosciences Chromatin IP Primers for PALMD Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PALMD
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 1p22-p21 Ensembl cytogenetic band: 1p21.2 HGNC cytogenetic band: 1p22-p21 PALMD Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc information about chromosome 1 GeneLoc Exon Structure
GeneLoc location for GC01P100111: view genomic region
(about GC identifiers )
Start:
100,111,431 bp from pter
End:
100,160,097 bp from pter
Size:
48,667 bases
Orientation:
plus strand
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Proteinsfor PALMD gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
Biochemical Assays by
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/Swiss-Prot: PALMD_HUMAN, Q9NP74 (See
protein sequence )Recommended Name: Palmdelphin Size : 551 amino acids; 62758 Da
Subunit : Interacts with GLUL (By similarity)
Subcellular location : Cytoplasm. Cell projection, dendrite. Cell projection, dendritic spine (By similarity)
Sequence caution : Sequence=CAC01336.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-Asequence;
Secondary accessions : Q9H7E6 Q9NPM5 Q9NPM6 Q9NPS0Alternative splicing : 3 isoforms : Q9NP74-1 Q9NP74-2 Q9NP74-3 Explore the universe of human proteins at neXtProt for PALMD: NX_Q9NP74 Post-translational modifications:
Phosphorylated (By similarity)1
View modification sites using PhosphoSitePlus 2 View neXtProt modification sites for NX_Q9NP74 PALMD Protein expression data from MOPED and PaxDb : About this image
REFSEQ proteins: NP_060204.1 ENSEMBL proteins: ENSP00000263174 Human Recombinant Protein Products: Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view) : About this table
PALMD for ontologies About GeneDecksing PALMD Antibody Products: Assay Products for PALMD:
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Protein
Domains / Familiesfor PALMD gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section
PALMD for domains About GeneDecksing 1 InterPro domain/family :
Graphical View of Domain Structure for InterPro Entry Q9NP74 ProtoNet protein and cluster: Q9NP74
UniProtKB/Swiss-Prot: PALMD_HUMAN, Q9NP74 Similarity : Belongs to the paralemmin family
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Functionfor PALMD gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences ,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Clone Products: Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for PALMD (see all 3 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for PALMD (see all 2 )OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: PALMD (NM_017734 ) Browse Sino Biological Human cDNA Clones DNA2.0 Custom Codon Optimized Gene
Synthesis Service for PALMD Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat PALMD
In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PALMD
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view) : About this table
GO ID Qualified GO term Evidence PubMed IDs GO:0005515 protein binding
-- --
PALMD for ontologies About GeneDecksing 1 GenomeRNAi human phenotype for PALMD :
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Pathways & Interactionsfor PALMD gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for PALMD STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)3 Interacting proteins for PALMD (Q9NP74 3 ENSP00000263174 4 ) via UniProtKB, MINT, STRING , and/or I2D About this table Gene Ontology (GO): 1 biological process term (GO ID links to tree view) : About this table
GO ID Qualified GO term Evidence PubMed IDs GO:0008360 regulation of cell shape
IEA --
PALMD for ontologies About GeneDecksing
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Drugs & Compoundsfor PALMD gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for PALMD Search CenterWatch for drugs/clinical trials and news about PALMD
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Transcriptsfor PALMD gene (Secondary structures according to
fRNAdb ,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
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siRNAs from
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
microRNA from QIAGEN ,
Tagged/untagged cDNA clones from
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GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for PALMD gene: NM_017734.4 Unigene Cluster for PALMD:
Palmdelphin Hs.483993 [show with all ESTs ] Unigene Representative Sequence: BX648213 2 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000263174 (uc001dsg.3 ) ENST00000496843 Clone Products: OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for PALMD (see all 3 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for PALMD (see all 2 )OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: PALMD (NM_017734 ) DNA2.0 Custom Codon Optimized Gene
Synthesis Service for PALMD Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat PALMD
Additional cDNA sequence: AF262379.1 AJ312214.1 AK000278.1 AK024654.1 AL390969.1 AL390970.1 AL390971.1 AL390972.1 AL390973.1 BC012570.1 BC058838.1 BX648213.1
7 DOTS entries : DT.80101445 DT.91828254
DT.40248245 DT.100812996 DT.95151846 DT.100813003 DT.92442173 24/178 AceView cDNA sequences (see all 178 ):
BU193265 AA336616 BM713006 AL390971 AI032975 AL390969 AL390973 BU623122 BC058838 AA777822 BU178612 N36894 CR603507 CA431306 BM989543 CK429905 AL545872 BM922152 AI347319 AA299103 AF262379 AI039717 AL390972 BM976645 GeneLoc Exon Structure
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Expression for PALMD gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,
PCR Arrays from
SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section PALMD expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: TGAATAAGTA
About this image PALMD expression in embryonic tissues and stem cells Expression by the Database of Embryonic development, Stem cell research, and
Regenerative medicine About this table See PALMD Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for PALMD SOURCE GeneReport for Unigene cluster: Hs.483993 UniProtKB/Swiss-Prot: PALMD_HUMAN, Q9NP74 Tissue specificity : Ubiquitous. Most abundant in cardiac and skeletal muscle SABiosciences Custom PCR Arrays for PALMD Primer Products: OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for PALMDBrowse OriGene validated miRNA SYBR primer pairs SABiosciences RT2 qPCR Primer Assay in human , mouse , rat PALMD QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat PALMD QIAGEN QuantiFast Probe-based Assays in human , mouse , rat PALMD In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PALMD
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Orthologsfor PALMD gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section
This gene was present in the common ancestor of chordates.
Orthologs for PALMD gene from 4/11 species (see all 11 ) About this table
Organism
Taxonomic classification
Gene
Description
Human Similarity
Orthology Type
Details
chicken (Gallus gallus)
Aves
PALMD1
palmdelphin
64.52(n) 57.46(a)
 
424475 XM_422318.3 XP_422318.1
lizard (Anolis carolinensis)
Reptilia
PALMD6
--
53(a)
1 ↔ 1
4(93265222-93294306)
African clawed frog (Xenopus laevis)
Amphibia
palmd-prov2
palmdelphin
75.47(n)
 
BC045267.1
zebrafish (Danio rerio)
Actinopterygii
palmda1
palmdelphin a
53.83(n) 43.95(a)
 
559824 XM_683200.4 XP_688292.4
ENSEMBL Gene Tree for PALMD (if available)TreeFam Gene Tree for PALMD (if available)
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Paralogsfor PALMD gene (Paralogs according to
1 HomoloGene , 2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section Paralogs for PALMD gene PALM 2 AKAP2 2 PALM2 2 PALM2-AKAP2 2
PALMD for paralogs About GeneDecksing
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Genomic Variantsfor PALMD gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section
Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical significance Chr 1 pos Sequence # AA Chg Type More # Allele freq Pop Total sample More
HapMap Linkage Disequilibrium report for PALMD (100111431 - 100160097 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 2 variations for PALMD 1 CNV : 4237 1 Indel : 97449
SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing PALMD
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Disorders
/ Diseasesfor PALMD gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section
PALMD for disorders About GeneDecksing
OMIM gene information: 610182
OMIM disorders : --1 disease for PALMD : About MalaCards vesicoureteral reflux Human Genome Epidemiology (HuGE) Navigator: PALMD (2 documents) Export disorders for PALMD gene to outside databases
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Publicationsfor PALMD gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for PALMD gene, integrated from 9 sources (see all 13 ): (articles sorted by number of sources associating them with PALMD) Utopia : connect your pdf to the dynamic world of online information
The paralemmin protein family: identification of paralemmin-2, an isoform differentially spliced to AKAP2/AKAP-KL, and of palmdelphin, a more distant cytosolic relative. (PubMed id 11478809) 1 , 2 , 3, 9 Hu B.... Kilimann M.W. (2001) Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983) 1 , 2 Olsen J.V....Mann M. (2006) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334) 1 , 2 Gerhard D.S....Malek J. (2004) Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039) 1 , 2 Ota T.... Sugano S. (2004) PALML, a novel paralemmin-related gene mapping on human chromosome 1p21. (PubMed id 11707320) 1 , 2 Andreu N.... Sumoy L. (2001) Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614) 1 Rose J.E....Uhl G.R. (2010) Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231) 2 Olsen J.V....Mann M. (2010) Genetic variants associated with cardiac structure an d function: a meta-analysis and replication of genome-wide association data. (PubMed id 19584346) 1 Vasan R.S....Blankenberg S. (2009) Proteins recruited by SH3 domains of Ruk/CIN85 adaptor identified by LC-MS/MS. (PubMed id 19531213) 1 Havrylov S....Redowicz M.J. (2009) Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis. (PubMed id 18220336) 2 Cantin G.T....Yates J.R. III (2008)
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External Searches for PALMD gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing PALMD gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
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Other Databases showing PALMD gene
(According to HUGE )
About This Section --
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Specialized Databases showing PALMD gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description
PharmGKB entry for PALMD Pharmacogenomics, SNPs, Pathways
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About This Section Patent Information for PALMD gene: Search GeneIP for patents involving PALMD GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor PALMD gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript and LifeMap BioReagents , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences ), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
Browse OriGene Antibodies OriGene shRNA RFP for PALMD OriGene 29mer shRNA kits in GFP-retroviral vector in human , mouse , rat for PALMD OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for PALMD OriGene Protein Over-expression Lysate for PALMD Browse OriGene Fluorogenic Cell Assay Kits OriGene siRNA for PALMD OriGene 3'-UTR Clone for PALMD OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for PALMD OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for PALMD Browse OriGene GFP tagged cDNA clones in CMV expression vector Browse OriGene MicroRNA Expression Plasmids Browse OriGene basic RS shRNAs Browse OriGene validated miRNA SYBR primer pairs OriGene Purified Protein for PALMD OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling OriGene Custom Antibody Services for PALMD OriGene Custom Protein Services for PALMD OriGene Custom Immunoassay Development
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat PALMD QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing PALMD QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PALMD QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human , mouse , rat PALMD QIAGEN QuantiFast Probe-based Assays in human , mouse , rat PALMD QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat PALMD
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PALMD Proteins, Antibodies, CLIAs, and ELISAs
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PALMD
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Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat PALMD
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Aliases for PALMD
Databases for PALMD
Disorders / Diseases for PALMD
Domains / Families for PALMD
Drugs / Compounds for PALMD
Expression for PALMD
Function for PALMD
Genomic Views for PALMD
Intellectual Property for PALMD
Orthologs for PALMD
Paralogs for PALMD
Pathways / Interactions for PALMD
Products for PALMD
Proteins for PALMD
Publications for PALMD
Search Box for PALMD
Summaries for PALMD
Transcripts for PALMD
Variants for PALMD
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