Free for academic non-profit institutions. Other users need a Commercial license

Aliases for PAGE5 Gene

Aliases for PAGE5 Gene

  • P Antigen Family, Member 5 (Prostate Associated) 2 3
  • Prostate-Associated Gene 5 Protein 3 4
  • G Antigen Family E Member 1 3 4
  • Cancer/Testis Antigen 16.1 3 4
  • CT16.1 3 4
  • GAGEE1 3 4
  • PAGE-5 3 4
  • Cancer/Testis Antigen Family 16, Member 1 3
  • Cancer/Testis Antigen Family 16, Member 2 3
  • Cancer/Testis Antigen Family 16 2
  • P Antigen Family Member 5 3
  • Member 1 2
  • Member 2 2
  • CT16.2 3
  • CT16 3

External Ids for PAGE5 Gene

Summaries for PAGE5 Gene

Entrez Gene Summary for PAGE5 Gene

  • This gene is a member of family of proteins that are expressed in a variety of tumors and in some fetal and reproductive tissues. The encoded protein may protect cells from programmed cell death. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found. [provided by RefSeq, Jan 2015]

GeneCards Summary for PAGE5 Gene

PAGE5 (P Antigen Family, Member 5 (Prostate Associated)) is a Protein Coding gene. Diseases associated with PAGE5 include hepatocellular fibrolamellar carcinoma. An important paralog of this gene is PAGE3.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PAGE5 Gene

Genomics for PAGE5 Gene

Genomic Location for PAGE5 Gene

Start:
55,089,045 bp from pter
End:
55,288,785 bp from pter
Size:
199,741 bases
Orientation:
Plus strand

Genomic View for PAGE5 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for PAGE5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PAGE5 Gene

No data available for Regulatory Elements for PAGE5 Gene

Proteins for PAGE5 Gene

  • Protein details for PAGE5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96GU1-PAGE5_HUMAN
    Recommended name:
    P antigen family member 5
    Protein Accession:
    Q96GU1
    Secondary Accessions:
    • Q2NL97
    • Q5JUL0
    • Q8WWL9

    Protein attributes for PAGE5 Gene

    Size:
    130 amino acids
    Molecular mass:
    14046 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for PAGE5 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for PAGE5 Gene

Proteomics data for PAGE5 Gene at MOPED

Post-translational modifications for PAGE5 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for PAGE5 Gene

No data available for DME Specific Peptides for PAGE5 Gene

Domains for PAGE5 Gene

Protein Domains for PAGE5 Gene

InterPro:
Blocks:
ProtoNet:

UniProtKB/Swiss-Prot:

PAGE5_HUMAN
Family:
  • Belongs to the GAGE family.:
    • Q96GU1
genes like me logo Genes that share domains with PAGE5: view

No data available for Gene Families for PAGE5 Gene

Function for PAGE5 Gene

genes like me logo Genes that share phenotypes with PAGE5: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for PAGE5 Gene

Localization for PAGE5 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for PAGE5 Gene COMPARTMENTS Subcellular localization image for PAGE5 gene
Compartment Confidence
cytosol 2
nucleus 2
extracellular 1

No data available for Gene Ontology (GO) - Cellular Components for PAGE5 Gene

Pathways for PAGE5 Gene

SuperPathways for PAGE5 Gene

No Data Available

Interacting Proteins for PAGE5 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000289619%0d%0a9606.ENSP00000350249%0d%0a
Selected Interacting proteins: ENSP00000289619 for PAGE5 Gene via STRING

Symbol External ID(s) Details
POT1

Gene Ontology (GO) - Biological Process for PAGE5 Gene

None

No data available for Pathways by source for PAGE5 Gene

Transcripts for PAGE5 Gene

mRNA/cDNA for PAGE5 Gene

Unigene Clusters for PAGE5 Gene

P antigen family, member 5 (prostate associated):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for PAGE5 Gene

No ASD Table

Relevant External Links for PAGE5 Gene

GeneLoc Exon Structure for
PAGE5
ECgene alternative splicing isoforms for
PAGE5

Expression for PAGE5 Gene

mRNA expression in normal human tissues for PAGE5 Gene

mRNA differential expression in normal tissues according to GTEx for PAGE5 Gene

This gene is overexpressed in Testis (47.4).

Integrated Proteomics: protein expression from ProteomicsDB, MOPED, and MaxQB for PAGE5 Gene

SOURCE GeneReport for Unigene cluster for PAGE5 Gene Hs.668491

genes like me logo Genes that share expressions with PAGE5: view

Orthologs for PAGE5 Gene

This gene was present in the common ancestor of mammals.

Orthologs for PAGE5 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia PAGE5 36
  • 99.23 (n)
  • 97.69 (a)
PAGE5 37
  • 98 (a)
OneToOne
dog
(Canis familiaris)
Mammalia -- 37
  • 44 (a)
ManyToMany
Species with no ortholog for PAGE5:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for PAGE5 Gene

ENSEMBL:
Gene Tree for PAGE5 (if available)
TreeFam:
Gene Tree for PAGE5 (if available)

Paralogs for PAGE5 Gene

Paralogs for PAGE5 Gene

Selected SIMAP similar genes for PAGE5 Gene using alignment to 2 proteins:

Pseudogenes.org Pseudogenes for PAGE5 Gene

genes like me logo Genes that share paralogs with PAGE5: view

Variants for PAGE5 Gene

Sequence variations from dbSNP and Humsavar for PAGE5 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs2148982 -- 55,222,616(-) CCTTA(A/G)AGATA intron-variant
rs4614133 -- 55,222,210(+) TTGCA(A/G/T)CTTCC intron-variant
rs4826274 -- 55,221,657(+) TCTCT(A/C)TATAT intron-variant
rs4826378 -- 55,219,263(+) TAATA(A/C)CTAGT upstream-variant-2KB
rs4826379 -- 55,220,109(+) TTGTC(C/T)GAAAC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for PAGE5 Gene

Variant ID Type Subtype PubMed ID
nsv435891 CNV Deletion 17901297
esv2740175 CNV Deletion 23290073
esv2740181 CNV Deletion 23290073

Relevant External Links for PAGE5 Gene

HapMap Linkage Disequilibrium report
PAGE5

Disorders for PAGE5 Gene

(1) University of Copenhagen DISEASES for PAGE5 Gene

genes like me logo Genes that share disorders with PAGE5: view

No data available for UniProtKB/Swiss-Prot for PAGE5 Gene

Publications for PAGE5 Gene

  1. The XAGE family of cancer/testis-associated genes: alignment and expression profile in normal tissues, melanoma lesions and Ewing's sarcoma. (PMID: 11992404) Zendman A.J.W. … van Muijen G.N.P. (Int. J. Cancer 2002) 2 3 4
  2. Identification of cancer/testis genes by database mining and mRNA expression analysis. (PMID: 11920606) Scanlan M.J. … Old L.J. (Int. J. Cancer 2002) 2 3
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 3 4
  5. Detection of melanoma-derived cancer-testis antigen CT16 in patient sera by a novel immunoassay. (PMID: 20658534) Rappu P. … Heino J. (Int. J. Cancer 2011) 3

Products for PAGE5 Gene

Sources for PAGE5 Gene

Back to Top

Content