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Aliases for PAGE3 Gene

Aliases for PAGE3 Gene

  • PAGE Family Member 3 2 3 5
  • P Antigen Family, Member 3 (Prostate Associated) 2 3
  • Prostate-Associated Gene 3 Protein 3 4
  • G Antigen Family D Member 1 3 4
  • G Antigen, Family D, 1 2 3
  • GAGED1 3 4
  • PAGE-3 3 4
  • CT16.6 3

External Ids for PAGE3 Gene

Previous HGNC Symbols for PAGE3 Gene

  • GAGED1

Previous GeneCards Identifiers for PAGE3 Gene

  • GC0XM055168
  • GC0XM052334

Summaries for PAGE3 Gene

Entrez Gene Summary for PAGE3 Gene

  • This gene is a member of family of proteins that are expressed in a variety of tumors and in some fetal and reproductive tissues. Multiple alternatively spliced transcript variants have been observed. [provided by RefSeq, Jan 2015]

GeneCards Summary for PAGE3 Gene

PAGE3 (PAGE Family Member 3) is a Protein Coding gene. An important paralog of this gene is PAGE5.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PAGE3 Gene

Genomics for PAGE3 Gene

Regulatory Elements for PAGE3 Gene

Enhancers for PAGE3 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around PAGE3 on UCSC Golden Path with GeneCards custom track

Genomic Location for PAGE3 Gene

55,258,412 bp from pter
55,463,452 bp from pter
205,041 bases
Minus strand

Genomic View for PAGE3 Gene

Genes around PAGE3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
PAGE3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PAGE3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PAGE3 Gene

Proteins for PAGE3 Gene

  • Protein details for PAGE3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    P antigen family member 3
    Protein Accession:
    Secondary Accessions:
    • A5D6Y1

    Protein attributes for PAGE3 Gene

    113 amino acids
    Molecular mass:
    12480 Da
    Quaternary structure:
    No Data Available

neXtProt entry for PAGE3 Gene

Proteomics data for PAGE3 Gene at MOPED

Post-translational modifications for PAGE3 Gene

No Post-translational modifications

Other Protein References for PAGE3 Gene

No data available for DME Specific Peptides for PAGE3 Gene

Domains & Families for PAGE3 Gene

Protein Domains for PAGE3 Gene


Suggested Antigen Peptide Sequences for PAGE3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the GAGE family.
  • Belongs to the GAGE family.
genes like me logo Genes that share domains with PAGE3: view

No data available for Gene Families for PAGE3 Gene

Function for PAGE3 Gene

Phenotypes for PAGE3 Gene

genes like me logo Genes that share phenotypes with PAGE3: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for PAGE3 Gene

Localization for PAGE3 Gene

Subcellular locations from

Jensen Localization Image for PAGE3 Gene COMPARTMENTS Subcellular localization image for PAGE3 gene
Compartment Confidence
mitochondrion 2
nucleus 2
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for PAGE3 Gene

Pathways & Interactions for PAGE3 Gene

SuperPathways for PAGE3 Gene

No Data Available

Interacting Proteins for PAGE3 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
Selected Interacting proteins: ENSP00000364089 Q5JUK9-PAGE3_HUMAN for PAGE3 Gene via STRING UniProtKB

Gene Ontology (GO) - Biological Process for PAGE3 Gene


No data available for Pathways by source and SIGNOR curated interactions for PAGE3 Gene

Drugs & Compounds for PAGE3 Gene

No Compound Related Data Available

Transcripts for PAGE3 Gene

mRNA/cDNA for PAGE3 Gene

(9) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(5) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for PAGE3 Gene

P antigen family, member 3 (prostate associated):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for PAGE3 Gene

No ASD Table

Relevant External Links for PAGE3 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for PAGE3 Gene

mRNA expression in normal human tissues for PAGE3 Gene

mRNA differential expression in normal tissues according to GTEx for PAGE3 Gene

This gene is overexpressed in Testis (x52.7).

SOURCE GeneReport for Unigene cluster for PAGE3 Gene Hs.163473

genes like me logo Genes that share expression patterns with PAGE3: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for PAGE3 Gene

Orthologs for PAGE3 Gene

This gene was present in the common ancestor of mammals.

Orthologs for PAGE3 Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia -- 36
  • 44 (a)
(Pan troglodytes)
Mammalia PAGE3 36
  • 98 (a)
Species with no ortholog for PAGE3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for PAGE3 Gene

Gene Tree for PAGE3 (if available)
Gene Tree for PAGE3 (if available)

Paralogs for PAGE3 Gene

Paralogs for PAGE3 Gene

(9) SIMAP similar genes for PAGE3 Gene using alignment to 1 proteins: Pseudogenes for PAGE3 Gene

genes like me logo Genes that share paralogs with PAGE3: view

Variants for PAGE3 Gene

Sequence variations from dbSNP and Humsavar for PAGE3 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs4826381 - 55,263,341(+) GTCAT(C/T)ACTGG reference, missense
rs2296807 - 55,263,287(+) TTGAC(A/C/T)AGGTG reference, missense
rs747673306 -- 55,447,790(+) TCCAT(A/G)CTCAT intron-variant
rs747676541 -- 55,300,911(+) TGTAC(C/T)GAGTA intron-variant
rs747677806 -- 55,362,387(+) AGGAA(C/T)GAGAT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for PAGE3 Gene

Variant ID Type Subtype PubMed ID
nsv435891 CNV Deletion 17901297
esv2740175 CNV Deletion 23290073
esv2740181 CNV Deletion 23290073

Variation tolerance for PAGE3 Gene

Gene Damage Index Score: 0.97; 19.98% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for PAGE3 Gene

Disorders for PAGE3 Gene

Relevant External Links for PAGE3

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for PAGE3 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for PAGE3 Gene

Publications for PAGE3 Gene

  1. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 3 4 67
  2. PAGE-1, an X chromosome-linked GAGE-like gene that is expressed in normal and neoplastic prostate, testis, and uterus. (PMID: 9724777) Brinkmann U. … Pastan I. (Proc. Natl. Acad. Sci. U.S.A. 1998) 2 3
  3. Genome-wide association study of smoking behaviours among Bangladeshi adults. (PMID: 24665060) Argos M. … Ahsan H. (J. Med. Genet. 2014) 3
  4. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for PAGE3 Gene

Sources for PAGE3 Gene