PAGE3 Gene
protein-coding GIFtS: 37
GCID: GC0XM055301
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P antigen family, member 3 (prostate associated)(Previous names: G antigen, family D, 1 )
(Previous symbol: GAGED1)
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Aliases
for PAGE3 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA
Quality score for the ORGUL clustered with this gene is 3
| Aliases |
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| P Antigen Family, Member 3 (Prostate Associated)1 2 | | G Antigen, Family D, 11 | | GAGED11 2 3 | | Prostate-Associated Gene 3 Protein3 | | PAGE-31 2 3 | | GAGEC15 | | CT16.61 2 | | |
| External Ids: | HGNC: 41101 | Entrez Gene: 1397932 | Ensembl: ENSG000002042797 | OMIM: 3007395 | UniProtKB: Q5JUK93 |
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| | ORGUL members: | |
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| NONCODE:n409271 | |
Export aliases for PAGE3 gene to outside databasesPrevious GC identifers: GC0XM055168 GC0XM052334
Summaries
for PAGE3 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
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Genomic Views
for PAGE3 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000023.10 NC_018934.1 NT_011630.14
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the PAGE3 gene promoter:
Nkx3-1 v2 Nkx3-1 Nkx3-1 v4 Nkx3-1 v3 Nkx3-1 v1 CUTL1
Other transcription factors
Search SABiosciences Chromatin IP Primers for PAGE3
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PAGE3 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: Xp11.21 Ensembl cytogenetic band: Xp11.21 HGNC cytogenetic band: Xp11PAGE3 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome X GeneLoc Exon Structure GeneLoc location for GC0XM055301: view genomic region
(about GC identifiers)
Start:
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55,284,848 bp from pter |
End:
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55,291,279 bp from pter |
Size:
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6,432 bases |
Orientation:
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minus strand |
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Proteins
for PAGE3 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
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UniProtKB/Swiss-Prot: GGED1_HUMAN, Q5JUK9 (See
protein sequence)Recommended Name: Putative G antigen family D member 1 Size: 113 amino acids; 12480 Da
Secondary accessions: A5D6Y1Explore the universe of human proteins at neXtProt for PAGE3: NX_Q5JUK9
PAGE3 Protein expression data from MOPED and PaxDb: About this image 
ENSEMBL proteins: ENSP00000364089 ENSP00000429571
Human Recombinant Protein Products:
PAGE3 Antibody Products:
Assay Products for PAGE3: |
Protein
Domains /
Families
for PAGE3 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
PAGE3 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q5JUK9ProtoNet protein and cluster: Q5JUK9 1 Blocks protein family: IPB008625 GAGE
UniProtKB/Swiss-Prot: GGED1_HUMAN, Q5JUK9Similarity: Belongs to the GAGE family |
Function
for PAGE3 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
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Pathways & Interactions
for PAGE3 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
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Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for PAGE3
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Drugs & Compounds
for PAGE3 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for PAGE3
Search CenterWatch for drugs/clinical trials and news about PAGE3 / GGED1 
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Transcripts
for PAGE3 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
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REFSEQ mRNAs for PAGE3 gene: NM_001017931.1 Unigene Cluster for PAGE3: P antigen family, member 3 (prostate associated) Hs.163473 [show with all ESTs]Unigene Representative Sequence: CD5590362 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000374951(uc022bxs.1 uc011mon.2) ENST00000519203
Additional cDNA sequence: BC140001.1 BC140741.1 BC144449.1 NR_033460.1 2 DOTS entries: DT.40245891 DT.100738252 5 AceView cDNA sequences: CD519391 CD559036 BX104655 AI392665 AA907594
GeneLoc Exon Structure
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Expression
for PAGE3 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| PAGE3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CAGTCTTTAT
About this image
See PAGE3 Protein Expression from SPIRE MOPED and PaxDB
SOURCE GeneReport for Unigene cluster: Hs.163473
SABiosciences Custom PCR Arrays for PAGE3
Primer
Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PAGE3
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat PAGE3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PAGE3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PAGE3 |
Orthologs
for PAGE3 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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ENSEMBL Gene Tree for PAGE3 (if available)
TreeFam Gene Tree for PAGE3 (if available) |
Paralogs
for PAGE3 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for PAGE3 gene
- PAGE22 GAGE2D2 GAGE42 XAGE32 GAGE102 GAGE12H2 GAGE12I2 XAGE52
- XAGE2B2 PAGE52 GAGE12C2 GAGE12E2 GAGE12D2 GAGE12 PAGE2B2 GAGE2E2
- GAGE2C2 GAGE12F2 PAGE12 GAGE132 XAGE22 GAGE12G2 GAGE2A2 GAGE2B2
- PAGE42 GAGE12J2
9 SIMAP similar genes for PAGE3 using alignment to 1 protein entry: GGED1_HUMAN:XAGE5 PAGE2 PAGE2B XAGE2 XAGE2B XAGE3
PAGE5 PAGE4 XAGE-4
PAGE3 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for PAGE3
PGOHUM00000239819
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Genomic Variants
for PAGE3 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
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| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr X pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
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HapMap Linkage Disequilibrium report for PAGE3 (55284848 - 55291279 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for PAGE3
1 CNV: 23256
Locus Specific Mutation Databases (LSDB): PAGE3
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PAGE3 |
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Disorders
/ Diseases
for PAGE3 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
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PAGE3 for disorders About GeneDecksing
OMIM gene information: 300739
OMIM disorders: --
1  disease for PAGE3: About MalaCardsprostatitis
Export disorders for PAGE3 gene to outside databases
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Publications
for PAGE3 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
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PubMed articles for PAGE3 gene integrated from 9 sources:
(articles sorted by number of sources associating them with PAGE3) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The DNA sequence of the human X chromosome. (PubMed id 15772651)1, 2 Ross M.T.... Bentley D.R. (2005)
- PAGE-1, an X chromosome-linked GAGE-like gene that is expressed in normal and neoplastic prostate, testis, and uterus. (PubMed id 9724777)1, 3 Brinkmann U....Pastan I. (1998)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
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External Searches for PAGE3 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing PAGE3 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
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Other Databases showing PAGE3 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing PAGE3 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for PAGE3 | Pharmacogenomics, SNPs, Pathways |
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About This Section
| Patent Information for PAGE3 gene:
Search GeneIP for patents involving PAGE3
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for PAGE3 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for PAGE3 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for PAGE3 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PAGE3 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for PAGE3 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PAGE3 | | Browse OriGene Myc/DDK tagged cDNA clones in CMV expression vector | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for PAGE3 | | OriGene Custom Protein Services for PAGE3 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat PAGE3 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PAGE3 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PAGE3 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat PAGE3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PAGE3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PAGE3 |
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| | | | Search Tocris compounds for PAGE3 |
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 | | | PAGE3 Proteins, Antibodies, CLIAs, and ELISAs |
| | | |  |  |  | | | | Search ThermoFisher Antibodies for PAGE3 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PAGE3 |
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Last full update: 18 Mar 2013 -
Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013
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